Best TWAS P=2.11e-10 · Best GWAS P=6.39e-10 conditioned to 0.554
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C7orf63 | 0.19 | 0.20 | enet | 9 | 0.19 | 3.8e-23 | -5.7 | 5.5 | 3.8e-08 | -0.78 | 0.19 | 0.81 | FALSE |
| 2 | GTEx | Pituitary | GTPBP10 | 0.22 | 0.01 | enet | 8 | 0.01 | 1.6e-01 | -3.8 | 5.2 | 1.6e-07 | -0.77 | 0.07 | 0.48 | FALSE |
| 3 | GTEx | Prostate | GTPBP10 | 0.20 | 0.00 | lasso | 6 | 0.00 | 2.4e-01 | -5.7 | 5.4 | 7.0e-08 | -0.77 | 0.06 | 0.69 | FALSE |
| 4 | NTR | Blood | GTPBP10 | 0.01 | 0.02 | lasso | 3 | 0.01 | 3.8e-05 | -6.0 | 6.0 | 1.8e-09 | -0.83 | 0.03 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | STEAP1 | 0.01 | 0.00 | blup | 40 | 0.01 | 1.1e-02 | -4.0 | -5.4 | 5.2e-08 | 0.87 | 0.03 | 0.80 | FALSE |
| 6 | The Cancer Genome Atlas | Colon Adenocarcinoma | STEAP1 | 0.04 | 0.03 | blup | 40 | 0.04 | 2.9e-03 | -5.6 | -5.9 | 3.5e-09 | 0.96 | 0.01 | 0.75 | FALSE |
| 7 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | STEAP1 | 0.09 | 0.02 | lasso | 7 | 0.01 | 1.3e-01 | -4.0 | -5.4 | 8.4e-08 | 0.85 | 0.02 | 0.82 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DPY19L2P4 | 0.07 | 0.03 | lasso | 3 | 0.02 | 1.9e-03 | -6.1 | 6.3 | 2.1e-10 | -0.94 | 0.00 | 0.98 | TRUE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | STEAP1 | 0.02 | 0.01 | blup | 40 | 0.01 | 1.8e-02 | -6.1 | -6.1 | 8.6e-10 | 0.94 | 0.01 | 0.86 | FALSE |