TWAS hub - GTF2IRD2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1290	0.0470	8.5e-05	-0.002	NA	0.003	NA	-0.001	5.6e-01	NA	1.8e-01	NA	4.1e-01
2	GTEx	Breast Mammary Tissue (Male)	0.2523	0.1306	5.4e-03	0.100	NA	-0.008	NA	0.038	2.6e-03	NA	5.5e-01	NA	4.7e-02
3	GTEx	Breast Mammary Tissue (Female)	0.0214	0.0288	2.5e-01	0.019	NA	0.030	NA	-0.008	8.9e-02	NA	4.3e-02	NA	6.3e-01
4	GTEx	Lung	0.1901	0.0726	6.9e-04	0.007	NA	-0.003	NA	-0.002	9.1e-02	NA	5.8e-01	NA	4.8e-01
5	GTEx	Muscle Skeletal	0.0501	0.0255	6.5e-03	0.018	NA	-0.001	NA	0.008	6.4e-03	NA	4.9e-01	NA	4.5e-02
6	GTEx	Nerve Tibial	0.0849	0.0407	1.9e-03	0.088	NA	0.073	NA	0.075	8.6e-07	NA	7.5e-06	NA	5.4e-06
7	GTEx	Skin Sun Exposed Lower leg	0.0710	0.0300	1.1e-03	0.045	NA	0.021	NA	0.050	1.3e-04	NA	6.6e-03	NA	5.2e-05
8	GTEx	Testis	0.1710	0.0810	5.8e-03	0.000	NA	0.003	NA	0.003	3.1e-01	NA	2.4e-01	NA	2.3e-01
9	GTEx	Thyroid	0.0770	0.0370	4.5e-03	0.066	NA	0.007	NA	0.045	9.4e-06	NA	8.0e-02	NA	2.4e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	2	3	4	5	6	7	8	9
Alcohol drinker status: Previous	5.2	5.9	11.5	1.9	1.9	1.4	2.1	3.4	3.2	2.7	3.3
Relative age voice broke	4.3	6.5	14.2	1.9	1.6	2.7	-0.1	-3.8	-2.6	-3.4	-3.5
Other serious medical condition/disability diagnosed by doctor	4.1	5.3	13.2	-0.9	-1.5	-0.8	1.0	3.6	2.9	3.2	3.4
Number of self-reported non-cancer illnesses	4.0	7.0	17.4	-1.2	-0.3	-3.0	-1.1	4.2	2.3	3.8	3.7
Age when periods started (menarche)	3.9	9.4	28.1	-0.6	-1.1	1.4	0.2	-5.3	-3.3	-4.4	-4.7
Impedance of leg (right)	3.6	17.2	43.7	-0.7	1.5	0.4	-3.3	-6.6	-6.0	-4.3	-6.6
Number of treatments/medications taken	3.5	6.4	14.1	-2.3	0.7	-3.6	-1.1	3.8	2.2	2.5	3.5
Irritable Bowel Disease (IBD)	3.4	8.1	21.5	1.1	0.6	0.7	-1.3	-4.5	-3.4	-4.6	-4.0
Mean time to correctly identify matches	3.4	6.5	14.8	1.2	1.0	0.6	1.7	3.9	3.3	3.7	3.7
Alcohol intake frequency.	3.4	7.8	22.2	-0.2	-0.6	-2.2	0.1	4.7	3.1	3.9	4.3
Mouth/teeth dental problems: Dentures	3.3	5.5	14.2	-0.7	-0.0	-1.3	0.7	3.7	2.7	3.8	3.4
Illnesses of siblings: Diabetes	3.3	4.1	12.4	-0.6	-0.6	-0.6	0.5	3.2	2.2	3.5	2.8
BMI	3.2	18.4	44.4	-3.2	-1.6	-4.3	0.7	6.7	5.0	4.6	6.6
Impedance of whole body	3.2	16.3	42.4	-0.2	2.0	0.5	-2.9	-6.5	-5.8	-4.0	-6.5
Body mass index (BMI)	3.1	13.3	31.9	-1.7	-1.7	-4.4	-0.3	5.7	3.9	4.3	5.4
Diabetes (self-reported)	3.1	4.8	16.8	-1.6	1.3	-1.6	-1.4	3.1	1.3	4.1	2.5
Long-standing illness, disability or infirmity	3.1	4.7	12.9	-2.0	0.9	-2.6	-1.2	2.9	1.4	3.6	2.4
Impedance of leg (left)	3.0	14.4	36.9	-0.5	1.1	0.2	-2.9	-6.1	-5.5	-4.0	-6.1
Vascular/heart problems diagnosed by doctor	3.0	8.3	18.7	-0.7	-2.3	3.2	1.5	-4.3	-2.2	-4.3	-3.8
Cardiovascular Disease	2.9	9.5	25.4	0.1	1.2	-2.4	-0.3	5.0	3.2	4.6	4.6
Lung FEV1/FVC ratio	2.9	14.6	31.1	1.1	0.7	2.1	4.6	5.3	5.6	3.9	5.4
Hypertension (Self-reported)	2.9	8.1	21.3	1.1	2.1	-2.9	-1.4	4.3	2.1	4.6	3.6
Diabetes diagnosed by doctor	2.9	4.8	16.1	-2.1	1.1	-1.3	-1.1	3.2	1.5	4.0	2.5
Average weekly beer plus cider intake	2.9	4.2	9.0	0.1	2.6	-1.3	-2.9	-2.2	-3.0	0.6	-2.7
Taking other prescription medications	2.8	4.3	10.8	-0.1	1.2	-2.3	-1.2	3.2	1.5	3.3	2.7
Ever taken oral contraceptive pill	2.8	3.1	9.3	-0.9	-0.3	-2.8	-3.1	-1.4	-2.2	-0.6	-1.5
Ulcerative Colitis (UC)	2.7	5.0	12.1	0.3	1.5	0.6	-1.4	-3.4	-2.8	-3.5	-3.1
Type 2 Diabetes (T2D) (2018)	2.7	5.0	18.3	-2.4	1.1	0.2	0.1	3.2	1.9	4.3	2.6
High blood pressure	2.7	7.7	19.0	0.9	1.6	-3.0	-1.3	4.2	2.2	4.4	3.6
Mouth/teeth dental problems	2.6	4.0	17.7	-0.0	0.4	1.2	0.2	-3.0	-1.6	-4.2	-2.3
Medication for cholesterol, blood pressure or diabetes	2.6	4.3	9.2	0.8	-2.2	2.8	1.5	-3.0	-1.5	-1.9	-2.8
Medication: Metformin	2.5	3.5	10.9	-2.5	-0.4	-0.5	-0.9	2.7	1.2	3.3	2.1
Medication: Ramipril	2.5	3.2	9.4	-0.0	0.4	-1.5	0.3	3.1	2.3	1.6	3.0
Arm fat percentage (right)	2.5	9.7	23.5	-2.3	-0.5	-4.8	-1.1	4.3	2.6	3.8	4.1
Medication: Blood pressure	2.5	4.4	9.2	0.4	2.4	-2.7	-1.7	3.0	1.4	2.1	2.7
Waist circumference	2.4	8.9	21.5	-0.3	-1.2	-4.2	-0.6	4.6	3.1	3.1	4.5
Impedance of arm (right)	2.4	11.1	27.7	0.4	3.0	0.2	-2.5	-5.2	-4.7	-2.8	-5.3
Arm fat percentage (left)	2.4	9.6	23.3	-2.2	-0.7	-4.8	-1.2	4.3	2.5	3.9	4.0
Risk taking	2.4	3.5	9.4	-3.1	-0.7	-2.8	-2.3	-1.4	-1.9	-0.7	-1.5
Unable to work because of sickness or disability	2.4	3.1	8.1	-0.7	-0.5	-2.3	0.2	2.8	2.1	1.3	2.8
Crohns Disease (2017)	2.3	5.0	12.9	1.9	-0.1	1.0	-0.2	-3.5	-2.3	-3.6	-3.1
Reaction Time	2.3	4.4	8.9	1.7	0.4	1.4	1.5	3.0	2.6	2.9	2.9
Illnesses of mother	2.3	2.8	6.7	-1.9	-0.3	-0.9	-0.5	-2.6	-1.8	-2.4	-2.2
Medication: Paracetamol	2.3	3.8	8.2	-1.9	-1.4	-1.0	1.7	2.7	2.7	1.6	2.9
Medication: Amlodipine	2.3	3.2	8.7	0.9	0.8	-1.5	-0.1	2.9	2.1	1.9	2.9
Medication: Paracetamol	2.3	3.5	7.6	-2.2	-0.6	-1.3	1.5	2.6	2.5	1.4	2.8
Impedance of arm (left)	2.2	10.3	26.9	0.3	2.6	0.6	-2.3	-5.1	-4.6	-2.6	-5.2
Headache pain in last month	2.2	3.7	9.0	-0.8	-0.4	-0.3	1.3	3.0	2.4	2.9	2.7
Cholesterol lowering medication	2.2	3.3	9.0	-0.5	-0.6	-1.1	0.8	3.0	2.4	2.0	2.9
Arm fat mass (right)	2.1	8.8	19.8	-1.4	-1.0	-4.4	-0.7	4.5	2.9	3.2	4.3
Overall health rating	2.1	4.5	12.7	-1.0	-0.2	-1.6	-1.4	3.6	1.7	3.2	3.0
Arm fat mass (left)	2.1	8.6	20.0	-1.4	-1.0	-4.5	-1.0	4.4	2.7	3.3	4.1
Medication: Lisinopril	2.1	2.7	8.4	-0.5	0.4	-0.6	0.1	2.9	2.1	1.6	2.8
Number of operations (self-reported)	2.1	3.1	8.8	-1.0	0.1	0.2	1.0	2.9	2.5	1.4	3.0
Leg fat mass (left)	2.1	8.1	21.9	-1.4	-1.8	-4.7	-1.6	4.0	2.1	3.1	3.7
Diabetes (mother)	2.0	2.5	5.3	-0.1	-2.2	0.2	1.1	2.3	2.0	1.3	2.3
Medication: Atenolol	2.0	2.5	5.8	-1.3	-0.8	-1.7	-0.2	2.4	1.6	1.8	2.3
Qualifications: O levels/GCSEs or equivalent	2.0	3.2	7.8	1.8	-0.8	0.7	-0.2	-2.8	-1.9	-2.5	-2.5
Leg fat mass (right)	2.0	7.7	22.6	-1.6	-1.9	-4.8	-1.8	3.7	1.8	3.0	3.4
Mood swings	2.0	3.7	6.7	-2.0	0.1	-2.0	-2.4	-2.1	-2.6	-1.5	-2.4
Mother’s age at death	2.0	2.5	5.1	1.0	2.0	2.3	1.1	-2.1	-0.9	-1.5	-1.8
Leg fat percentage (left)	2.0	7.3	20.0	-2.3	-1.8	-4.5	-1.7	3.5	1.7	3.1	3.2
Chronotype (morning person)	1.9	4.4	11.1	-1.2	-0.9	0.7	3.1	2.6	3.3	0.3	3.0
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.4	11.0	-1.1	-0.7	-0.9	-1.2	-3.3	-2.7	-2.8	-3.1
Heart disease (mother)	1.9	2.3	6.5	2.5	0.3	0.6	0.0	2.1	1.3	2.0	1.8
Handedness (chirality/laterality): Left-handed	1.9	2.3	5.3	0.9	1.3	0.5	-0.6	-2.3	-1.7	-2.3	-2.1
Medication: Gliclazide	1.9	2.1	6.1	-0.9	-0.2	1.1	1.5	1.8	1.7	2.5	1.6
Supplements: Fish oil (including cod liver oil)	1.9	2.5	5.0	-1.5	1.5	-1.8	-2.2	-1.5	-1.8	-1.4	-1.4
Commuting to job workplace: Car/motor vehicle	1.8	2.1	3.5	-1.6	-0.2	-1.9	-1.5	-1.7	-1.8	-1.1	-1.7
Osteoarthritis (self-reported)	1.8	2.4	6.1	-0.4	-0.7	-1.5	-0.7	2.4	1.2	2.5	2.1
Age started oral contraceptive pill	1.8	2.3	4.9	2.1	2.2	0.1	1.1	1.6	1.7	0.8	1.8
Major Depression (MDD)	1.7	2.1	6.8	-2.5	0.0	-2.6	-1.9	-0.3	-1.1	0.4	-0.5
HbA1C	1.7	1.9	3.3	-1.0	1.4	1.6	-0.8	-1.7	-1.6	-1.4	-1.8
Neuroticism (2016)	1.7	2.4	5.4	-2.3	-0.7	0.2	-1.4	-2.1	-2.0	-1.0	-2.1
Relative age of first facial hair	1.7	3.4	7.1	2.5	0.9	2.7	1.8	-2.3	-0.8	-1.9	-1.9
Diabetes (father)	1.7	2.1	5.1	-0.1	-1.6	0.5	1.0	2.1	1.7	2.2	1.8
Maternal smoking around birth	1.7	2.5	10.2	-2.9	-0.6	-3.2	-1.9	0.3	-0.5	-0.1	0.3
Qualifications: CSEs or equivalent	1.7	2.2	4.3	-1.0	-1.4	-2.1	-1.9	-1.4	-1.7	-1.5	-1.4
Body fat percentage	1.7	6.9	24.5	-2.1	-0.8	-5.0	-2.1	3.2	1.3	2.9	2.8
Leg fat percentage (right)	1.7	6.1	19.0	-2.4	-1.5	-4.4	-2.0	2.9	1.1	2.7	2.5
Breast Cancer	1.6	3.8	11.0	-1.0	-2.6	1.4	1.2	-2.6	-1.0	-3.3	-2.0
Qualifications: None of the above	1.6	3.3	8.0	-2.4	0.3	-2.8	-1.6	2.1	0.7	2.5	1.7
Medication: Lansoprazole	1.6	1.8	4.4	0.4	0.7	-2.1	-1.3	2.0	0.8	1.4	1.7
Ever highly irritable/argumentative for 2 days	1.6	1.9	8.2	-2.0	0.0	-2.9	-1.2	1.2	0.2	1.1	0.9
Medication: Omeprazole	1.6	1.9	4.3	0.6	1.8	-0.3	0.6	2.1	1.6	1.7	1.8
Whole body fat mass	1.6	6.8	20.2	-1.1	-1.2	-4.5	-1.7	3.6	1.8	2.8	3.3
Medication: Blood pressure	1.6	3.1	8.8	0.4	-0.2	-1.1	-0.1	2.8	1.8	3.0	2.5
Commuting to job workplace: Cycle	1.6	2.0	3.7	0.6	0.3	1.2	1.8	1.9	1.9	1.6	1.8
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.4	8.9	-0.9	-1.1	-0.6	-0.6	-2.9	-2.0	-3.0	-2.5
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	11.0	-0.1	-3.3	0.3	1.5	1.0	1.5	0.2	1.2
Pulse rate	1.5	2.5	9.5	-0.4	-0.5	-2.9	-3.1	-0.7	-1.7	-0.5	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	8.4	-2.1	1.0	-2.9	-2.4	0.2	-0.9	0.4	-0.1
Medication for cholesterol	1.5	2.3	5.2	1.1	0.2	1.9	0.4	-2.3	-1.3	-2.3	-1.9
Trunk fat percentage	1.4	5.6	23.7	-1.6	-0.5	-4.9	-2.2	2.5	0.8	2.4	2.3
Townsend deprivation index at recruitment	1.4	2.0	5.3	-2.3	1.5	-1.3	-0.6	1.9	1.1	0.2	1.9
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	4.0	-0.5	-0.5	0.5	1.2	2.0	1.8	1.6	1.8
Hip circumference	1.4	6.1	15.6	0.2	-0.8	-2.9	-0.6	4.0	2.5	3.3	3.6
Noisy workplace	1.4	1.7	3.4	-0.5	1.0	-1.5	0.4	1.8	1.4	1.8	1.7
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	4.2	1.3	1.0	0.8	-0.6	-1.6	-1.3	-2.0	-1.5
Medication: Cholesterol lowering	1.4	2.2	6.8	-1.7	1.5	-2.6	-2.2	1.2	-0.0	0.3	1.0
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	7.3	-0.2	-1.8	-1.1	-1.0	1.5	0.4	2.7	1.0
Qualifications: College or University degree	1.4	4.5	15.6	2.2	0.1	2.5	3.9	1.4	2.8	0.2	1.9
Eye problems/disorders: None of the above	1.4	1.6	6.5	0.0	0.1	0.3	2.5	1.1	2.0	0.2	1.5
Medication for pain relief, constipation, heartburn	1.4	2.4	5.3	1.8	0.2	1.7	-0.5	-2.2	-1.9	-1.2	-2.3
Alcohol drinker status: Never	1.4	1.6	4.0	0.8	0.7	-1.8	-0.5	2.0	1.2	1.0	1.9
Basal cell carcinoma (self-reported)	1.4	1.7	2.8	-1.7	1.5	-0.3	0.5	1.7	1.4	1.6	1.7
Alzheimer’s Disease (in mother)	1.3	1.5	3.6	-0.1	0.5	0.0	-1.3	-1.7	-1.9	-1.2	-1.9
Body Mass Index (BMI) (2010)	1.3	1.8	4.4	-0.7	1.2	0.0	0.4	2.1	1.6	1.6	2.1
Sensitivity / hurt feelings	1.3	2.2	14.1	-0.7	-0.0	3.8	1.6	-0.7	0.1	-1.5	-0.7
Systolic blood pressure, automated reading	1.3	3.7	11.3	1.2	1.9	-1.5	-1.2	2.7	1.1	3.4	2.1
Pack years adult smoking proportion	1.3	2.0	4.5	-0.0	-1.6	-1.0	-1.9	2.0	0.3	2.1	1.4
Trunk fat mass	1.3	5.7	22.9	-0.9	-0.9	-4.8	-1.9	3.0	1.3	2.3	2.7
Wheeze or whistling in the chest in last year	1.3	2.3	8.0	-0.8	0.1	-2.7	-2.8	1.1	-0.6	1.7	0.6
Shortness of breath walking on level ground	1.3	1.5	3.9	0.3	-0.2	-2.0	-0.6	1.8	1.0	1.4	1.7
Pulse rate, automated reading	1.3	4.1	10.2	-2.4	-0.4	-3.2	-1.9	2.5	0.9	2.4	2.2
Back pain experienced in last month	1.3	1.9	4.3	-0.8	0.0	-1.1	0.4	2.1	1.6	2.0	2.0
Diastolic blood pressure, automated reading	1.3	4.1	7.5	2.4	2.2	-1.9	-1.7	2.7	0.9	2.7	2.1
Prostate Cancer	1.2	1.7	4.3	0.6	1.2	0.7	-0.4	-2.1	-1.6	-1.6	-2.0
Lupus	1.2	1.8	6.0	-2.4	-1.2	-2.4	-1.3	0.7	0.2	-0.5	0.9
Frequency of depressed mood in last 2 weeks	1.2	1.7	8.4	-2.9	0.2	-2.1	-1.5	-0.3	-0.8	0.1	-0.4
Fed-up feelings	1.2	2.1	5.1	-1.0	-0.5	-1.6	-2.3	-1.5	-2.0	-1.0	-1.7
Weight	1.2	6.1	17.6	0.4	-1.3	-4.2	-1.2	3.6	2.0	2.2	3.4
Hair/balding pattern: Pattern 3	1.2	1.8	4.1	1.2	1.6	2.0	1.3	1.3	1.5	0.5	1.3
Average weekly champagne plus white wine intake	1.2	1.6	6.6	-0.1	-0.9	1.4	-0.1	-1.6	-0.9	-2.6	-1.2
High cholesterol (Self-reported)	1.2	2.2	9.2	-0.2	0.1	-3.0	-1.7	1.9	0.6	1.0	1.6
Medication: Bendroflumethiazide	1.2	1.8	4.4	1.1	0.6	-1.9	-1.2	1.7	0.5	2.1	1.3
Pack years of smoking	1.2	1.8	5.0	0.1	-1.2	-1.1	-1.9	1.9	0.2	2.2	1.2
Ulcerative Colitis	1.1	1.5	4.5	0.0	1.6	0.0	-0.3	-1.7	-1.2	-2.1	-1.5
Smoking Status	1.1	2.7	7.7	-2.8	-0.3	-1.3	-2.2	-1.3	-1.8	-1.8	-1.4
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	2.4	0.8	1.6	0.2	1.1	1.2	1.3	1.4	1.2
High blood pressure (mother)	1.1	1.6	4.9	1.7	-0.7	0.4	0.6	1.6	1.2	2.2	1.3
Alcohol usually taken with meals	1.1	1.7	4.3	2.0	0.4	2.1	1.4	-0.6	0.4	-2.1	-0.1
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	3.5	-1.9	-0.2	-1.5	-1.5	-0.9	-1.4	-0.4	-1.1
Medication: Simvastatin	1.1	1.6	4.8	-0.4	0.2	-1.1	-0.6	2.2	1.3	1.2	2.1
Illnesses of siblings	1.1	1.5	5.3	0.8	-1.1	0.6	0.9	-1.7	-0.6	-2.3	-1.3
Depression (self-reported)	1.1	1.3	5.5	-0.8	0.7	-2.4	-2.0	-0.0	-0.9	0.6	-0.3
Medication: Allopurinol	1.1	1.4	5.3	-0.5	-0.4	-2.1	-2.3	-0.5	-1.2	-0.8	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	3.5	0.6	-1.9	-1.8	-1.8	-0.5	-1.1	-0.4	-0.6
Smoking status: Current	1.1	1.7	7.5	-0.4	-0.4	-1.6	-2.7	-0.6	-1.6	-1.2	-0.8
Ever smoked	1.1	2.0	5.3	-2.3	1.7	1.5	1.4	1.2	1.4	0.4	1.2
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	2.9	0.2	1.7	-0.5	0.3	1.7	1.1	1.7	1.4
Crohns Disease (2012)	1.0	1.6	3.9	1.6	0.0	0.0	0.5	-2.0	-1.1	-1.9	-1.8
Respiratory disease	1.0	2.3	6.5	-2.6	-2.3	-1.8	-2.1	-0.0	-0.9	-0.0	-0.2
Supplements: Zinc	1.0	1.1	3.1	1.1	-0.2	0.6	-0.0	-1.6	-0.9	-1.7	-1.3
Current tobacco smoking	1.0	1.7	7.4	-0.4	0.1	-1.7	-2.7	-0.4	-1.4	-1.3	-0.6
Pain all over the body in last month	1.0	1.1	3.7	-1.9	-0.3	-1.7	-1.1	-0.2	-0.4	-1.2	-0.0
Father’s age at death	1.0	1.4	3.9	-0.7	0.3	-0.3	-0.8	-1.9	-1.7	-0.8	-2.0
Qualifications: A levels/AS levels or equivalent	1.0	2.2	4.6	1.4	0.0	2.0	1.1	-2.1	-0.8	-2.1	-1.7
Standing height	1.0	10.1	19.4	4.1	0.7	0.1	-2.2	-4.2	-3.8	-4.4	-4.1
Birth weight	1.0	2.1	4.3	1.9	-0.9	1.0	-0.2	-2.1	-1.4	-1.7	-1.9
Chronic bronchitis/emphysema (mother)	1.0	1.2	4.9	-2.2	-1.1	-1.5	0.0	0.9	0.7	0.1	1.0
Number of children fathered	1.0	1.1	7.9	-2.8	-0.9	-0.8	0.0	-0.4	-0.1	-0.6	-0.2
Medication: Aspirin	1.0	1.3	2.9	-0.4	1.3	-1.6	-0.5	1.7	1.1	0.8	1.7
Guilty feelings	1.0	1.6	8.3	-2.9	1.9	-0.5	-0.5	-0.7	-0.6	-0.6	-0.6
Commuting to job workplace: Public transport	1.0	1.2	2.9	0.6	1.2	1.7	1.2	1.0	1.2	1.1	1.0
Fractured/broken bones in last 5 years	1.0	1.3	3.1	-0.7	-0.6	0.7	-0.6	-1.8	-1.5	-1.2	-1.8
Stomach or abdominal pain in last month	0.9	1.1	2.4	0.6	-0.0	0.6	1.1	1.5	1.5	1.2	1.5
Hair/balding pattern: Pattern 2	0.9	1.2	2.7	0.2	-0.7	1.0	1.6	1.2	1.6	0.9	1.3
Allergy	0.9	2.1	4.4	0.3	1.7	2.1	1.5	-1.9	-0.6	-1.9	-1.5
Hair/balding pattern: Pattern 4	0.9	2.3	5.1	-2.2	-1.7	-1.7	-1.8	-1.1	-1.6	-0.7	-1.3
Peak expiratory flow (PEF)	0.9	2.2	7.5	-0.5	-0.4	-2.7	-1.9	-1.4	-1.6	-1.4	-1.3
Loud music exposure frequency	0.9	1.0	3.5	0.2	1.9	-1.2	-0.4	0.6	0.2	1.8	0.4
Chest pain or discomfort	0.9	1.2	3.1	-0.7	0.4	-1.1	0.0	1.8	1.1	1.6	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	2.6	0.2	1.2	-1.6	-0.4	1.6	0.9	0.5	1.5
Illnesses of father: High blood pressure	0.9	1.1	3.0	1.3	1.7	1.1	-0.9	-0.7	-1.1	0.8	-1.1
Intelligence (Savage-Jansen 2018)	0.8	2.5	8.5	-0.5	0.0	1.9	1.2	-2.2	-0.9	-2.9	-1.8
Ovarian Cancer	0.8	1.0	2.8	0.6	-0.6	1.7	0.8	-1.3	-0.5	-1.4	-1.1
Primary Biliary Cirrhosis	0.8	1.1	2.7	-0.3	-0.1	1.1	-0.3	-1.6	-1.2	-1.4	-1.6
Systolic Blood Pressure	0.8	4.1	9.9	2.2	1.4	-0.9	-0.4	3.1	1.9	2.7	2.8
Hand grip strength (left)	0.8	2.1	5.2	0.7	-1.1	-0.6	-1.4	-2.1	-2.2	-0.9	-2.3
Ever had hysterectomy (womb removed)	0.8	0.9	1.8	0.9	0.3	-1.2	-1.4	1.2	0.2	1.2	1.0
Serious illness, injury or assault to yourself	0.8	0.9	2.5	-1.6	-0.9	-1.4	-1.2	0.6	-0.2	1.2	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	6.3	-2.5	0.8	-0.7	-0.8	0.9	0.2	1.4	0.6
Alcohol intake versus 10 years previously	0.8	1.1	4.6	-2.1	-1.2	-1.3	-0.2	1.0	0.5	0.8	0.8
Asthma	0.8	1.6	5.0	-1.6	-1.3	-2.1	-2.2	0.2	-0.8	0.5	0.0
Worry too long after embarrassment	0.8	1.4	4.3	-0.8	-0.3	-0.6	-2.1	-1.1	-1.8	-0.6	-1.4
Age at first live birth	0.8	1.3	5.2	2.0	0.3	0.5	1.2	-0.9	0.2	-2.3	-0.3
Angina (self-reported)	0.8	1.1	2.8	0.3	1.0	-1.2	-0.2	1.7	1.2	0.6	1.7
Medication: Aspirin	0.8	1.0	2.4	-0.5	0.6	-1.6	-0.4	1.5	1.0	0.6	1.5
Illnesses of father: Heart disease	0.8	1.1	3.5	0.4	1.3	-1.9	-1.6	-0.5	-0.9	-0.9	-0.5
Leg fat-free mass (right)	0.8	4.1	9.6	1.5	-1.8	-2.4	0.1	3.1	2.3	1.4	3.1
Average weekly red wine intake	0.8	1.1	2.8	0.2	1.6	1.7	0.5	-1.1	-0.4	-1.6	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	6.9	-0.2	-2.6	-0.1	-0.2	-0.5	-0.3	-0.7	-0.3
Mineral and other dietary supplements	0.8	1.0	2.2	0.5	-1.5	0.7	0.9	1.3	1.1	1.2	1.1
Asthma (self-reported)	0.8	1.6	5.2	-1.4	-1.3	-2.1	-2.3	0.1	-0.9	0.6	-0.1
Leg predicted mass (right)	0.8	4.1	9.6	1.5	-1.7	-2.4	0.0	3.1	2.3	1.4	3.1
Pain experienced in last month	0.8	1.4	5.0	1.0	0.9	2.2	0.1	-1.3	-1.0	-1.0	-1.4
Depression (Nagel 2018)	0.7	1.0	5.2	-2.3	0.0	-1.2	-1.1	-0.4	-0.7	0.2	-0.5
Height	0.7	12.9	22.8	3.9	1.5	-0.3	-3.4	-4.7	-4.7	-4.5	-4.8
Average weekly spirits intake	0.7	0.8	4.0	-2.0	-0.4	-1.7	-0.6	-0.2	-0.3	0.0	-0.2
Angina	0.7	1.0	2.1	0.2	1.3	-1.1	-0.3	1.5	1.0	0.6	1.5
Medication for hormone replacement therapy	0.7	0.8	1.8	-1.2	0.6	-1.3	-1.1	-0.4	-0.9	0.6	-0.7
Leg fat-free mass (left)	0.7	3.8	8.9	1.1	-1.6	-2.5	-0.2	3.0	2.1	1.4	3.0
Average weekly fortified wine intake	0.7	0.9	2.7	-1.6	-1.0	1.0	1.6	-0.5	0.4	-0.1	-0.3
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.4	-1.5	1.4	-1.1	-1.0	-0.2	-0.5	0.0	-0.2
Multivitamins +/- minerals	0.7	0.9	2.1	-1.1	0.4	-1.4	-1.3	-0.9	-1.0	-1.0	-0.6
Medication: Levothyroxine sodium	0.7	1.2	2.1	-1.1	-1.5	-1.5	0.3	1.4	1.1	0.5	1.4
Leg predicted mass (left)	0.7	3.9	9.1	1.1	-1.6	-2.6	-0.2	3.0	2.1	1.4	3.0
Number of incorrect matches in round	0.7	1.1	4.0	1.1	-1.1	-1.7	-2.0	0.1	-0.8	0.6	-0.1
Past tobacco smoking	0.7	1.2	8.2	2.9	-1.6	-0.2	0.0	-0.4	-0.2	-0.2	-0.3
Fluid intelligence score	0.7	1.5	4.7	0.4	-0.7	2.2	1.0	-1.3	-0.4	-2.0	-1.0
Time employed in main current job	0.7	0.8	2.2	0.4	0.3	0.7	-0.8	-1.3	-1.4	0.1	-1.5
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	4.0	-2.0	-1.2	-1.5	-1.2	0.6	-0.2	0.5	0.4
Prospective memory result	0.7	0.9	6.0	0.2	-2.4	0.5	0.5	-0.6	-0.2	-1.1	-0.4
Pulse wave reflection index	0.7	0.8	1.9	1.4	1.0	1.0	1.3	0.5	0.9	0.5	0.6
High blood pressure (siblings)	0.7	1.0	4.2	-0.4	0.9	-0.8	-1.3	1.1	0.0	2.0	0.7
Arm predicted mass (right)	0.7	3.5	8.6	1.2	-2.4	-1.5	0.5	2.8	2.3	0.6	2.9
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.0	0.4	-0.1	0.6	1.2	1.3	1.4	0.7	1.3
Wears glasses or contact lenses	0.7	0.8	1.8	0.3	0.9	0.4	-1.3	-1.1	-1.3	-0.7	-1.2
Ever depressed for a whole week	0.7	0.9	3.7	-1.9	-0.6	-0.6	0.2	0.9	0.6	1.3	0.8
Schizophrenia (2018)	0.6	1.3	5.6	0.0	1.0	0.0	-2.4	0.9	-0.6	1.9	0.4
Alzheimer’s Disease (including proxy)	0.6	0.9	2.0	-1.0	1.4	-0.4	-0.6	-1.2	-1.1	-0.4	-1.2
Age at First Birth	0.6	0.9	5.2	2.3	0.4	1.1	0.9	0.1	0.5	0.2	0.2
Mean Putamen Volume	0.6	0.7	1.9	-0.8	0.6	0.0	-0.1	-1.4	-0.8	-1.2	-1.1
Neuroticism	0.6	1.4	2.7	-1.1	1.2	0.5	-1.5	-1.4	-1.6	-1.0	-1.5
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.4	-0.6	1.5	0.2	-0.2	1.0	0.5	1.2	0.7
Had menopause	0.6	0.7	4.3	1.1	0.4	2.1	0.4	0.2	0.1	0.8	-0.1
Heart attack	0.6	0.7	1.5	-0.7	1.1	-1.1	-0.3	1.1	0.8	0.4	1.2
Neuroticism score	0.6	1.3	2.8	-1.2	0.7	0.1	-1.6	-1.3	-1.7	-0.8	-1.5
Number of live births	0.6	0.9	3.1	0.5	-0.5	1.7	0.8	-0.8	-0.0	-1.8	-0.4
Happiness	0.6	0.8	2.0	1.2	0.3	-0.5	-0.8	1.2	0.3	1.4	0.8
Arm fat-free mass (right)	0.6	3.0	7.2	1.2	-2.2	-1.5	0.3	2.6	2.1	0.5	2.7
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	4.2	-2.0	0.6	-0.4	0.5	0.6	0.7	0.4	0.7
Emphysema/chronic bronchitis	0.6	0.7	1.9	-1.1	0.1	-1.4	-0.3	0.9	0.6	0.8	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	1.2	-0.9	0.7	-0.3	-0.8	-1.1	-1.0	-0.9	-1.0
Knee pain experienced in last month	0.6	0.9	1.7	-1.0	-0.9	-0.6	0.5	1.3	1.1	1.1	1.3
Friendships satisfaction	0.6	0.7	4.8	0.4	-2.2	0.0	-0.2	0.2	0.1	-1.1	0.2
Financial situation satisfaction	0.6	0.7	3.6	0.2	0.1	0.3	0.2	1.2	0.8	1.9	0.9
Medication: Atorvastatin	0.6	0.8	1.7	-1.3	0.8	-1.1	-0.5	1.1	0.6	0.7	1.0
Basal metabolic rate	0.6	3.3	7.2	1.2	-1.7	-2.6	-0.3	2.6	1.8	0.8	2.7
Arm fat-free mass (left)	0.6	3.0	7.7	1.0	-1.8	-2.0	0.2	2.6	2.1	0.4	2.8
Heart disease (siblings)	0.6	0.7	2.2	-1.5	1.5	-0.6	-0.8	-0.4	-0.5	-0.9	-0.3
Arm predicted mass (left)	0.6	3.0	7.3	0.8	-1.8	-2.2	-0.0	2.6	2.0	0.6	2.7
Depressed Affect (Nagel 2018)	0.5	1.0	2.7	-0.9	0.0	-0.7	-1.6	-1.0	-1.4	-0.8	-1.2
Schizophrenia (2014)	0.5	1.2	7.7	0.0	0.4	0.0	-2.8	0.4	-1.0	1.2	-0.0
Heel T-Score	0.5	3.6	10.6	0.5	0.1	1.9	1.0	-3.2	-1.6	-2.9	-2.6
Hypothyroidism (self reported)	0.5	1.1	4.0	-1.3	-2.0	-0.7	0.5	1.0	1.0	-0.3	1.1
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.7	-1.6	-0.7	-1.0	-0.3	0.3	0.0	0.9	0.2
Medication: Co-codamol	0.5	0.6	2.0	-0.6	-0.6	-0.6	-1.4	-0.1	-0.6	-1.3	-0.2
Hand grip strength (right)	0.5	1.4	2.5	0.4	-1.5	-1.2	-1.4	-1.3	-1.6	-0.4	-1.5
Hayfever, allergic rhinitis or eczema	0.5	1.1	2.7	0.8	-1.6	-0.9	-0.9	1.4	0.6	1.2	1.2
Supplements: Glucosamine	0.5	0.7	3.4	-1.8	-0.5	-0.4	-0.7	-0.7	-0.7	-0.5	-0.6
Sitting height	0.5	3.2	9.5	1.6	0.9	-1.4	-1.8	-2.0	-1.9	-3.1	-1.8
Chronic bronchitis/emphysema (father)	0.5	0.6	1.7	-1.3	-0.6	-0.6	-0.7	-0.5	-0.8	1.0	-0.8
Forced vital capacity (FVC)	0.5	2.0	3.4	-0.2	0.7	-1.8	-1.7	-1.7	-1.8	-1.4	-1.7
Number of full brothers	0.5	0.7	3.0	-1.7	0.6	-1.4	-0.6	0.3	0.1	0.2	0.4
Neck or shoulder pain in last month	0.5	0.7	3.4	-1.3	-0.6	-1.8	-0.0	0.4	0.4	0.3	0.6
Migraine (self-reported)	0.5	0.6	2.9	-1.7	-0.0	-1.4	-0.7	0.2	-0.3	0.4	0.0
Medication: Ibuprofen	0.5	0.6	3.6	-1.9	0.4	-0.9	0.5	0.2	0.4	0.2	0.3
Medication: Seretide 50 evohaler	0.5	0.6	2.9	0.4	0.0	-0.3	-0.1	1.1	0.6	1.7	0.9
Age at last live birth	0.5	0.7	4.5	0.7	0.5	-0.4	0.7	-0.9	0.1	-2.1	-0.3
Smoking status: Previous	0.5	0.8	5.0	-2.2	1.2	0.7	0.6	-0.1	0.2	-0.3	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	3.8	0.3	-1.5	-0.9	-0.4	-1.2	-0.8	-2.0	-0.9
Whole body fat-free mass	0.5	2.7	6.1	1.7	-1.8	-1.8	0.1	2.4	1.8	0.4	2.5
Whole body water mass	0.5	3.0	7.0	1.6	-1.7	-1.9	0.2	2.5	2.0	0.6	2.6
Irritability	0.5	0.8	1.3	-0.9	0.7	-0.7	-1.0	-1.0	-1.1	-0.8	-1.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.2	1.5	0.4	-0.9	-0.6	0.4	0.2	-1.2	0.6
Supplements: Calcium	0.5	0.6	1.3	1.1	0.9	1.2	1.0	0.3	0.8	0.1	0.5
Alzheimer’s Disease (in father)	0.4	0.4	1.2	-0.1	1.1	-0.7	0.5	0.6	0.7	0.5	0.7
Fasting Glucose	0.4	0.4	1.1	-0.6	-0.4	-1.1	-0.6	0.7	0.2	1.0	0.6
Rheumatoid Arthritis	0.4	0.6	2.1	0.0	-0.2	0.0	-0.8	1.5	0.7	0.0	1.4
Blood Red Count	0.4	3.7	7.7	-2.4	-1.0	-2.8	-0.3	2.6	1.8	1.6	2.6
Allergy or Eczema	0.4	1.2	3.4	0.0	-0.6	-1.0	-1.1	1.6	0.5	1.9	1.3
Lung FVC	0.4	2.0	7.2	-1.9	0.4	-2.0	-0.6	1.3	0.5	2.7	0.9
Nervous feelings	0.4	0.7	4.4	0.1	-0.4	0.6	0.1	1.1	0.5	2.1	0.6
Had other major operations	0.4	0.5	1.3	-0.1	0.4	0.7	0.6	1.0	1.1	-0.1	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.6	-1.6	0.3	-0.9	0.3	-0.6	-0.2	-0.2	-0.4
Lung cancer (father)	0.4	0.4	1.3	0.1	-0.2	0.3	0.2	1.2	0.9	0.7	1.1
Pulse wave Arterial Stiffness index	0.4	0.5	2.0	1.4	0.9	0.7	0.4	0.4	0.4	0.4	0.3
Birth weight of first child	0.4	0.8	2.3	-0.4	0.5	1.5	0.7	-1.3	-0.6	-0.6	-1.2
Blood clot in the leg (DVT)	0.4	0.5	0.8	-0.5	-0.2	0.5	0.8	0.9	0.9	0.8	0.8
Glaucoma (self-reported)	0.4	0.5	1.2	-0.3	-0.2	0.7	-1.1	-0.5	-1.1	0.5	-0.9
Exposure to tobacco smoke outside home	0.4	0.6	2.2	-0.9	1.1	-0.6	-0.5	0.3	-0.2	1.5	0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.7	-1.0	1.0	-1.3	-1.0	0.1	-0.3	0.5	0.0
Health satisfaction	0.4	0.5	1.1	-0.5	1.0	-0.7	-0.1	1.1	0.6	0.6	0.9
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.5	0.1	1.2	0.0	1.0	0.6	0.8	1.0	0.6
Comparative height size at age 10	0.4	2.0	5.1	1.9	0.5	-2.2	-1.3	1.9	0.7	0.8	1.6
Family relationship satisfaction	0.4	0.5	2.3	1.0	-1.5	-0.2	-0.6	0.1	-0.3	0.6	-0.2
Leg pain on walking	0.4	0.5	1.6	0.1	-0.0	-0.6	0.1	0.9	0.7	1.3	0.9
Loneliness, isolation	0.4	0.6	1.3	0.2	-1.1	0.1	-0.8	-0.9	-1.0	-0.7	-1.0
Eye problems/disorders: Cataract	0.4	0.4	1.1	-0.5	0.7	-0.7	-1.0	-0.5	-0.7	-0.8	-0.5
Illnesses of father: None of the above (group 1)	0.4	0.4	1.4	-0.5	-0.1	0.2	1.2	0.6	1.1	-0.2	0.9
Miserableness	0.4	0.8	2.0	-1.1	0.3	-1.4	-1.4	-0.5	-1.0	-0.2	-0.7
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.5	-1.6	0.7	-0.2	-1.0	-0.2	-0.6	0.5	-0.4
Eye problems/disorders: Glaucoma	0.4	0.5	1.2	1.1	-0.8	0.8	-0.8	0.1	-0.6	0.9	-0.4
Heart attack/myocardial infarction (self-reported)	0.4	0.6	1.3	-0.5	1.0	-0.8	-0.0	1.0	0.8	0.4	1.1
Neuroticism (Nagel 2018)	0.3	0.7	1.4	-1.1	0.0	0.6	-1.1	-0.8	-1.2	-0.7	-1.0
Verbal and Numeric Reasoning (VNR)	0.3	0.8	4.4	0.7	-0.2	0.9	0.9	-0.7	0.1	-2.1	-0.3
Financial difficulties in last 2 years	0.3	0.4	2.9	-1.7	0.5	-0.4	-0.5	-0.1	-0.3	0.5	-0.2
Trunk fat-free mass	0.3	1.7	4.1	2.0	-1.5	-1.3	0.1	1.6	1.3	-0.2	1.7
Worrier / anxious feelings	0.3	0.6	1.4	-0.5	0.9	1.2	-0.9	-0.6	-0.9	-0.2	-0.9
Trunk predicted mass	0.3	1.7	3.9	2.0	-1.4	-1.4	0.0	1.6	1.3	-0.3	1.7
Length of working week for main job	0.3	0.3	1.2	-0.9	1.1	0.1	-0.1	-0.3	-0.4	0.3	-0.5
Exposure to tobacco smoke at home	0.3	0.3	1.4	0.5	0.9	-0.5	-1.2	0.1	-0.5	-0.0	-0.1
Tense / ‘highly strung’	0.3	0.4	1.3	-1.1	-0.1	0.6	-0.5	-0.3	-0.6	1.0	-0.6
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.0	-1.1	-1.4	-1.2	-0.3	0.5	0.3	-0.2	0.6
Pulse wave peak to peak time	0.3	0.4	0.8	-0.9	-0.9	-0.5	-0.5	-0.6	-0.6	-0.6	-0.5
Suffer from ‘nerves’	0.3	0.4	2.4	-0.1	0.7	1.5	0.3	0.1	0.1	0.9	0.0
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	3.8	-0.1	1.9	0.6	0.6	-0.3	0.0	-0.0	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	2.4	-1.6	0.1	-0.3	0.3	0.4	0.5	-0.5	0.5
Osteoporosis (self-reported)	0.3	0.4	1.1	0.1	-0.8	-0.2	0.2	1.0	0.7	0.7	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.1	-0.0	0.3	-1.5	-1.2	-0.0	-0.7	1.2	-0.4
Hearing aid user	0.3	0.3	2.1	-0.2	-1.4	0.0	0.5	-0.2	0.2	-0.5	-0.0
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.2	0.2	-0.3	0.3	-1.1	-0.6	-0.9	-0.3	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.8	-0.3	-0.6	0.3	0.4	0.9	0.6	0.9	0.7
Bipolar Disorder or Schizophrenia	0.2	0.5	2.8	0.0	0.5	0.0	-1.7	0.4	-0.5	1.1	0.2
Worry (Nagel 2018)	0.2	0.4	1.4	0.4	0.0	1.0	-1.2	-0.1	-0.8	0.7	-0.5
Blood Eosinophil Count	0.2	1.3	4.2	-0.7	-0.8	1.6	1.7	-0.4	0.7	-2.0	0.1
Blood White Count	0.2	1.2	4.5	-2.1	0.5	-1.5	0.4	1.0	1.1	-0.0	1.3
Hair Pigment	0.2	6.8	16.6	-4.1	-0.5	0.1	-2.8	-3.2	-3.6	-0.6	-3.6
Hearing difficulty/problems: Yes	0.2	0.4	1.1	-0.1	-0.7	-1.0	-1.1	-0.1	-0.5	-0.7	-0.2
Vitamin and mineral supplements	0.2	0.3	0.7	0.7	-0.3	0.8	0.4	-0.5	-0.3	-0.0	-0.7
Severe depression (siblings)	0.2	0.2	0.7	-0.6	0.2	-0.8	-0.8	0.3	-0.1	0.1	0.3
Falls in the last year	0.2	0.3	1.2	0.7	1.1	0.6	0.0	0.4	0.2	-0.0	0.2
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	2.7	0.0	0.3	-1.6	-0.7	-0.6	-0.7	-0.6	-0.6
Breastfed as a baby	0.2	0.3	0.8	0.9	0.5	-0.1	-0.6	-0.4	-0.7	0.2	-0.6
Gout (self-reported)	0.2	0.3	1.2	-0.2	-0.2	-1.1	-0.9	0.1	-0.2	-0.4	0.2
Forced vital capacity (FVC), Best measure	0.2	0.7	1.3	0.0	0.3	-1.0	-0.7	-1.1	-1.1	-0.9	-1.2
Number of full sisters	0.2	0.3	1.4	-0.3	-0.2	-0.7	0.2	-0.6	-0.2	-1.2	-0.3
Ever had bowel cancer screening	0.2	0.2	0.4	0.2	-0.6	0.6	0.6	0.4	0.6	-0.3	0.5
Qualifications: nursing, teaching	0.2	0.2	0.7	0.9	-0.6	0.0	0.5	-0.6	-0.2	-0.4	-0.5
Commuting to job workplace: Walk	0.2	0.2	0.7	0.1	0.1	0.9	0.4	0.6	0.5	0.4	0.4
Breast cancer (self-reported)	0.2	0.2	0.8	0.3	0.9	-0.1	-0.7	0.4	0.0	-0.1	0.4
Myopia	0.2	0.3	0.9	-0.1	0.2	0.3	0.1	-0.9	-0.6	-0.9	-0.8
HDL Cholesterol	0.1	0.2	0.5	0.2	0.1	0.0	0.3	-0.7	-0.4	-0.5	-0.7
Waist Hip Ratio (WHR)	0.1	0.5	1.9	0.5	-1.1	-0.3	0.7	-0.5	0.2	-1.4	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.7	-0.8	-0.0	-0.4	-0.6	-0.3	-0.4	0.2	-0.3
Hearing difficulty/problems with background noise	0.1	0.2	0.5	0.5	0.7	0.1	-0.7	-0.3	-0.6	-0.2	-0.5
Comparative body size at age 10	0.1	0.3	1.0	1.0	0.2	0.6	1.0	-0.3	0.3	-0.4	-0.1
Had major operations	0.1	0.1	0.5	-0.0	-0.7	0.1	0.2	0.4	0.4	-0.2	0.4
Supplements: Vitamin C	0.1	0.1	0.4	-0.2	0.1	-0.6	-0.2	0.6	0.3	0.5	0.5
Bipolar Disorder (2018)	0.0	0.0	0.2	0.0	-0.4	0.0	0.2	-0.4	-0.1	0.0	-0.2
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.5	1.9	-0.4	0.7	-0.5	0.6	0.7	0.7	1.4	0.7
Tanning	0.0	0.6	2.9	-0.3	0.7	-1.7	0.2	0.7	0.7	0.1	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.6	0.3	0.2	-0.7	0.1	-0.3	-0.2	0.0	-0.3
Medication: Ventolin 100micrograms inhaler	0.0	0.1	0.2	-0.1	0.1	0.4	-0.1	-0.4	-0.3	-0.2	-0.4

Hub : Genes

GTF2IRD2

Models

Trait associations