Best TWAS P=5.51e-12 · Best GWAS P=1.7e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MET | 0.08 | 0.07 | lasso | 4 | 0.07 | 4.5e-09 | -5.9 | 5.7 | 1.6e-08 | 0.56 | 0.82 | 0.18 | FALSE |
| 2 | GTEx | Artery Aorta | MET | 0.21 | 0.23 | lasso | 5 | 0.22 | 3.0e-12 | 6.3 | -6.9 | 5.5e-12 | -0.96 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Artery Tibial | MET | 0.13 | 0.11 | lasso | 8 | 0.10 | 6.4e-08 | 6.3 | -6.6 | 4.2e-11 | -0.91 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Brain Caudate basal ganglia | MET | 0.39 | 0.35 | enet | 25 | 0.30 | 2.1e-09 | -5.8 | 5.7 | 1.3e-08 | 0.57 | 0.83 | 0.17 | FALSE |
| 5 | GTEx | Brain Putamen basal ganglia | MET | 0.21 | 0.12 | lasso | 1 | 0.05 | 2.0e-02 | -6.0 | 6.0 | 2.6e-09 | 0.56 | 0.18 | 0.21 | FALSE |