TWAS
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Traits
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Traits
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Lung FEV1/FVC ratio
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chr8:100,277,018-101,937,374
Best TWAS P=1.33e-07 · Best GWAS P=5.53e-07 conditioned to 0.298
100.2M
100.4M
100.6M
100.8M
101M
101.2M
101.4M
101.6M
101.8M
102M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Testis
SPAG1
0.15
0.07
enet
6
0.10
5.2e-05
3.9
-5.3
1.3e-07
0.84
0.03
0.96
TRUE
1
CommonMind
Brain Pre-frontal Cortex
RGS22
0.08
0.02
enet
14
0.04
6.3e-06
2.9
5.2
2.1e-07
-0.63
0.24
0.57
FALSE