TWAS
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Traits
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Traits
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Lung FEV1/FVC ratio
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chr8:102,002,608-103,832,256
Best TWAS P=8.77e-11 · Best GWAS P=4.8e-16 conditioned to 1.6e-12
102M
102.5M
103M
103.5M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Testis
KB-1107E3.1
0.26
0.08
enet
31
0.10
2.8e-05
-6.6
6.5
8.8e-11
-0.18
0.56
0.07
TRUE
1
GTEx
Testis
NCALD
0.24
0.20
lasso
5
0.19
9.2e-09
-6.6
6.2
7.0e-10
0.10
0.95
0.02
FALSE