[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr8:108,515,373-110,190,556

Best TWAS P=3.04e-16 · Best GWAS P=1.56e-15 conditioned to 0.00171

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	YFS	Blood	EIF3E	0.01	0.00	blup	452	0.01	1.4e-04	-6.9	8.2	3.0e-16	0.70	0.21	0.68	TRUE
1	CommonMind	Brain Pre-frontal Cortex	EIF3E	0.07	0.07	bslmm	401	0.09	1.5e-11	-6.9	8.1	3.8e-16	0.75	0.83	0.17	FALSE
7	The Cancer Genome Atlas	Lung Adenocarcinoma	EIF3E	0.02	0.01	blup	38	0.01	6.0e-02	-6.9	7.7	1.8e-14	0.65	0.09	0.36	FALSE
4	GTEx	Muscle Skeletal	EMC2	0.05	0.04	lasso	3	0.02	2.7e-03	7.3	7.3	2.1e-13	0.93	0.19	0.74	FALSE
5	GTEx	Testis	EMC2	0.28	0.06	enet	70	0.03	2.3e-02	-6.2	6.8	7.9e-12	0.52	0.11	0.58	FALSE
3	GTEx	Esophagus Gastroesophageal Junction	EMC2	0.09	0.10	enet	13	0.03	2.2e-02	6.5	-6.7	2.2e-11	-0.85	0.10	0.64	FALSE
2	GTEx	Brain Cerebellum	EIF3E	0.16	0.04	lasso	9	0.10	7.9e-04	7.1	6.2	6.7e-10	0.52	0.09	0.34	FALSE
8	The Cancer Genome Atlas	Prostate Adenocarcinoma	EIF3E	0.02	0.02	blup	38	0.01	1.5e-02	-6.9	6.1	8.6e-10	0.69	0.10	0.24	FALSE
9	The Cancer Genome Atlas	Prostate Adenocarcinoma	TTC35	0.04	0.02	blup	52	0.03	2.8e-04	7.4	5.6	1.8e-08	0.84	0.05	0.87	FALSE