TWAS
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About
Usage
Models
Genes
Traits
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Traits
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Lung FEV1/FVC ratio
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chr8:120,254,953-121,763,223
Best TWAS P=3.91e-11 · Best GWAS P=1.09e-10 conditioned to 0.000178
120.2M
120.4M
120.6M
120.8M
121M
121.2M
121.4M
121.6M
121.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Testicular Germ Cell Tumors
DEPDC6
0.19
0.04
blup
142
0.11
1.1e-04
-4.6
6.6
3.9e-11
0.48
0.27
0.50
TRUE
2
GTEx
Lung
DEPTOR
0.16
0.12
enet
28
0.15
1.3e-11
-5.0
-6.3
2.5e-10
-0.31
0.96
0.04
FALSE
3
GTEx
Thyroid
RP11-760H22.2
0.15
0.13
lasso
4
0.12
8.2e-10
-4.4
5.8
8.3e-09
0.55
0.90
0.10
FALSE
1
GTEx
Brain Cerebellar Hemisphere
DEPTOR
0.32
0.15
lasso
8
0.29
3.4e-08
-5.0
5.6
1.9e-08
0.19
0.59
0.05
FALSE