Best TWAS P=3.91e-11 · Best GWAS P=1.09e-10 conditioned to 0.000178
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | DEPTOR | 0.32 | 0.15 | lasso | 8 | 0.29 | 3.4e-08 | -5.0 | 5.6 | 1.9e-08 | 0.19 | 0.59 | 0.05 | FALSE |
| 2 | GTEx | Lung | DEPTOR | 0.16 | 0.12 | enet | 28 | 0.15 | 1.3e-11 | -5.0 | -6.3 | 2.5e-10 | -0.31 | 0.96 | 0.04 | FALSE |
| 3 | GTEx | Thyroid | RP11-760H22.2 | 0.15 | 0.13 | lasso | 4 | 0.12 | 8.2e-10 | -4.4 | 5.8 | 8.3e-09 | 0.55 | 0.90 | 0.10 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | DEPDC6 | 0.19 | 0.04 | blup | 142 | 0.11 | 1.1e-04 | -4.6 | 6.6 | 3.9e-11 | 0.48 | 0.27 | 0.50 | TRUE |