[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr9:14,857,740-16,758,776

Best TWAS P=1.51e-11 · Best GWAS P=2.81e-12 conditioned to 0.0481

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Cortex	CCDC171	0.26	0.15	lasso	2	0.16	2.8e-05	-6.6	-6.8	1.5e-11	0.92	0.15	0.77	TRUE
7	GTEx	Nerve Tibial	CCDC171	0.25	0.16	lasso	6	0.14	2.1e-10	-6.5	-6.6	5.6e-11	0.89	0.10	0.90	FALSE
3	GTEx	Brain Cerebellum	CCDC171	0.46	0.22	lasso	7	0.15	3.4e-05	-6.3	-6.5	1.0e-10	0.88	0.14	0.85	FALSE
1	GTEx	Brain Caudate basal ganglia	CCDC171	0.30	0.18	lasso	4	0.23	2.4e-07	6.3	-6.4	1.7e-10	0.85	0.23	0.76	FALSE
9	GTEx	Pituitary	CCDC171	0.28	0.16	enet	29	0.12	5.2e-04	6.5	-6.4	1.8e-10	0.85	0.15	0.80	FALSE
2	GTEx	Brain Cerebellar Hemisphere	CCDC171	0.46	0.19	lasso	7	0.23	1.3e-06	-6.0	-6.2	6.6e-10	0.84	0.21	0.75	FALSE
8	GTEx	Ovary	CCDC171	0.21	0.19	lasso	4	0.16	7.7e-05	5.9	6.1	9.8e-10	-0.76	0.17	0.47	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	CCDC171	0.14	0.11	enet	21	0.11	8.3e-14	6.2	-5.9	4.3e-09	0.74	0.37	0.63	FALSE
5	GTEx	Brain Frontal Cortex BA9	CCDC171	0.27	0.18	enet	10	0.19	8.3e-06	6.3	-5.5	2.9e-08	0.76	0.21	0.62	FALSE
6	GTEx	Brain Hypothalamus	CCDC171	0.32	0.17	enet	6	0.09	4.0e-03	-6.0	-5.5	3.5e-08	0.82	0.12	0.60	FALSE
10	METSIM	Adipose	CCDC171	0.03	0.00	blup	828	0.01	4.0e-02	6.3	-5.5	4.8e-08	0.77	0.11	0.77	FALSE