[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr9:14,857,740-16,758,776

Best TWAS P=1.51e-11 · Best GWAS P=2.81e-12 conditioned to 0.0481

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia CCDC171 0.30 0.18 lasso 4 0.23 2.4e-07 6.3 -6.4 1.7e-10 0.85 0.23 0.76 FALSE
2 GTEx Brain Cerebellar Hemisphere CCDC171 0.46 0.19 lasso 7 0.23 1.3e-06 -6.0 -6.2 6.6e-10 0.84 0.21 0.75 FALSE
3 GTEx Brain Cerebellum CCDC171 0.46 0.22 lasso 7 0.15 3.4e-05 -6.3 -6.5 1.0e-10 0.88 0.14 0.85 FALSE
4 GTEx Brain Cortex CCDC171 0.26 0.15 lasso 2 0.16 2.8e-05 -6.6 -6.8 1.5e-11 0.92 0.15 0.77 TRUE
5 GTEx Brain Frontal Cortex BA9 CCDC171 0.27 0.18 enet 10 0.19 8.3e-06 6.3 -5.5 2.9e-08 0.76 0.21 0.62 FALSE
6 GTEx Brain Hypothalamus CCDC171 0.32 0.17 enet 6 0.09 4.0e-03 -6.0 -5.5 3.5e-08 0.82 0.12 0.60 FALSE
7 GTEx Nerve Tibial CCDC171 0.25 0.16 lasso 6 0.14 2.1e-10 -6.5 -6.6 5.6e-11 0.89 0.10 0.90 FALSE
8 GTEx Ovary CCDC171 0.21 0.19 lasso 4 0.16 7.7e-05 5.9 6.1 9.8e-10 -0.76 0.17 0.47 FALSE
9 GTEx Pituitary CCDC171 0.28 0.16 enet 29 0.12 5.2e-04 6.5 -6.4 1.8e-10 0.85 0.15 0.80 FALSE
10 METSIM Adipose CCDC171 0.03 0.00 blup 828 0.01 4.0e-02 6.3 -5.5 4.8e-08 0.77 0.11 0.77 FALSE
11 ROSMAP Brain Pre-frontal Cortex CCDC171 0.14 0.11 enet 21 0.11 8.3e-14 6.2 -5.9 4.3e-09 0.74 0.37 0.63 FALSE