[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr9:99,707,397-102,521,881

Best TWAS P=4.59e-18 · Best GWAS P=2.94e-14 conditioned to 0.531

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	COL15A1	0.07	0.01	enet	8	0.02	1.2e-02	7.1	8.7	4.6e-18	-0.68	0.02	0.79	TRUE
6	GTEx	Muscle Skeletal	XPA	0.07	0.04	enet	10	0.04	1.4e-04	6.7	6.7	1.6e-11	-0.02	0.01	0.99	TRUE
2	GTEx	Adrenal Gland	TSTD2	0.24	0.11	lasso	4	0.07	1.2e-03	6.8	6.3	3.0e-10	-0.03	0.01	0.96	TRUE
23	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	XPA	0.12	0.14	lasso	1	0.11	5.2e-04	6.2	-6.2	4.8e-10	0.01	0.04	0.45	TRUE
19	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NCBP1	0.16	0.02	blup	40	0.06	1.5e-03	-2.1	-5.4	8.5e-08	0.01	0.02	0.44	TRUE
7	GTEx	Ovary	C9orf156	0.39	0.23	enet	15	0.18	3.9e-05	-3.3	-5.3	1.3e-07	0.02	0.27	0.07	TRUE
16	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	COL15A1	0.12	0.14	enet	12	0.13	1.9e-14	7.2	8.3	7.3e-17	-0.44	0.04	0.96	FALSE
21	The Cancer Genome Atlas	Stomach Adenocarcinoma	COL15A1	0.05	0.00	enet	7	0.02	2.0e-02	7.1	8.3	9.1e-17	-0.46	0.05	0.58	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	COL15A1	0.12	0.12	enet	19	0.13	3.9e-25	7.2	7.8	7.7e-15	-0.45	0.03	0.97	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	COL15A1	0.05	0.04	enet	13	0.03	6.1e-04	6.8	7.7	2.1e-14	-0.38	0.09	0.75	FALSE
8	GTEx	Thyroid	COL15A1	0.10	0.06	lasso	5	0.04	2.2e-04	6.6	7.5	5.8e-14	-0.32	0.06	0.92	FALSE
18	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	COL15A1	0.18	0.06	blup	115	0.08	4.7e-04	6.9	7.4	1.0e-13	-0.54	0.02	0.90	FALSE
9	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	COL15A1	0.05	0.04	lasso	3	0.04	3.8e-04	7.2	7.2	5.8e-13	-0.23	0.05	0.88	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	COL15A1	0.05	0.05	lasso	1	0.04	1.7e-05	7.2	7.2	8.3e-13	-0.24	0.04	0.96	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	COL15A1	0.06	0.06	enet	10	0.06	5.5e-07	7.1	7.0	1.9e-12	-0.30	0.05	0.95	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	COL15A1	0.07	0.01	blup	115	0.03	2.8e-04	3.6	6.7	3.0e-11	-0.45	0.04	0.87	FALSE
5	GTEx	Lung	COL15A1	0.08	0.05	lasso	1	0.03	1.1e-03	6.6	6.6	3.1e-11	-0.24	0.08	0.58	FALSE
1	GTEx	Adipose Visceral Omentum	TSTD2	0.12	0.00	lasso	6	0.02	2.8e-02	6.1	6.6	4.7e-11	-0.01	0.05	0.68	FALSE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	COL15A1	0.17	0.10	blup	114	0.11	9.3e-13	7.1	6.4	1.2e-10	-0.38	0.04	0.96	FALSE
4	GTEx	Cells Transformed fibroblasts	COL15A1	0.09	0.06	enet	22	0.05	1.2e-04	2.1	6.2	4.9e-10	-0.35	0.19	0.78	FALSE
3	GTEx	Artery Tibial	TSTD2	0.08	0.04	lasso	2	0.05	4.3e-05	6.8	6.1	1.4e-09	-0.03	0.02	0.98	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	COL15A1	0.20	0.07	blup	115	0.09	8.3e-06	6.6	5.7	1.0e-08	-0.25	0.07	0.86	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	XPA	0.03	0.01	blup	43	0.03	2.0e-04	6.2	5.7	1.3e-08	-0.03	0.03	0.82	FALSE