TWAS hub - NCBP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Liver	0.405	0.142	0.0037	-0.010	NA	0.029	NA	0.025	0.790	NA	0.054	NA	0.068
2	TCGA	Pheochromocytoma and Paraganglioma	0.162	0.096	0.0021	0.022	0.064	0.032	NA	0.036	0.045	0.0015	0.020	NA	0.014

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Hypothyroidism/myxoedema (self-reported)	10.3	20.0	39.3	-0.9	6.3
Hypothyroidism (self reported)	9.7	22.2	44.4	-0.3	6.7
Medication: Levothyroxine sodium	8.6	14.5	28.7	0.5	5.4
Hearing aid user	5.2	5.9	8.8	3.0	1.7
Medication: Lisinopril	4.8	6.2	12.3	0.3	-3.5
Medication: Atenolol	4.0	5.0	10.0	-3.2	0.1
Number of full sisters	3.7	4.5	8.4	-2.9	0.8
Lung FEV1/FVC ratio	3.3	16.7	28.7	-2.2	-5.4
Alcohol drinker status: Never	3.3	4.0	7.7	2.8	0.6
Noisy workplace	3.1	3.9	4.1	-2.0	1.9
Depression (self-reported)	2.8	3.4	6.7	-2.6	0.1
Had menopause	2.7	3.4	6.0	0.8	-2.5
Lupus	2.6	4.0	5.4	2.3	-1.6
Vitamin and mineral supplements	2.6	3.5	4.5	1.6	2.1
Reason for reducing amount of alcohol drunk: Health precaution	2.6	3.0	5.4	-0.7	2.3
Myopia	2.6	3.8	4.2	-2.1	-1.8
Diabetes (father)	2.5	3.1	5.5	-2.3	0.9
Medication: Ramipril	2.5	3.3	5.8	0.8	2.4
Medication: Ibuprofen	2.1	2.6	3.0	1.7	-1.4
Had major operations	2.1	2.4	4.2	-0.8	2.1
Shortness of breath walking on level ground	1.9	2.3	4.6	2.1	0.0
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	2.2	1.5	-1.4
High blood pressure (mother)	1.7	2.3	4.0	-0.8	-2.0
Exposure to tobacco smoke at home	1.7	1.9	3.5	-1.9	-0.4
Tense / ‘highly strung’	1.7	2.8	5.5	-2.4	-0.4
Loud music exposure frequency	1.7	1.9	2.4	-1.2	1.5
High blood pressure (siblings)	1.7	2.4	2.6	1.5	-1.6
Worry too long after embarrassment	1.7	2.8	4.6	-2.1	-1.0
Medication for pain relief, constipation, heartburn	1.7	2.8	5.5	2.4	-0.3
Suffer from ‘nerves’	1.7	2.6	4.5	-2.1	-0.8
Medication: Omeprazole (e.g. Zanprol)	1.7	2.0	3.5	-0.8	-1.9
Neuroticism	1.6	3.8	4.0	-1.9	-2.0
Breastfed as a baby	1.6	2.0	3.6	-1.9	-0.6
Guilty feelings	1.6	2.4	4.2	0.8	-2.1
Average weekly beer plus cider intake	1.6	2.3	4.6	-0.3	2.1
Ever had prostate specific antigen (PSA) test	1.6	1.9	3.4	-0.6	-1.8
Neuroticism (Nagel 2018)	1.5	3.6	5.0	-1.5	-2.2
Type 2 Diabetes (T2D) (2012)	1.5	1.8	1.9	1.3	1.4
Type 2 Diabetes (T2D) (2018)	1.5	2.8	4.9	-2.2	-0.8
Diabetes (mother)	1.5	1.9	2.9	-1.7	-1.0
Fluid intelligence score	1.5	3.0	4.5	1.2	-2.1
Medication: Lansoprazole	1.5	1.7	3.1	0.5	-1.8
Supplements: Vitamin C	1.5	1.7	3.0	-0.7	-1.7
Financial situation satisfaction	1.5	1.8	2.4	1.1	-1.6
HbA1C	1.4	1.6	3.2	-1.8	-0.1
LDL Cholesterol	1.4	2.2	4.4	-2.1	-0.2
Age when periods started (menarche)	1.4	3.5	4.5	2.1	1.6
Fasting Glucose	1.3	1.6	2.2	-1.0	-1.5
Multivitamins +/- minerals	1.3	1.6	3.2	-0.1	-1.8
Had other major operations	1.3	1.6	3.2	-0.1	1.8
Number of live births	1.3	1.8	2.6	-1.0	1.6
Neck or shoulder pain in last month	1.3	1.9	3.8	2.0	-0.1
Comparative height size at age 10	1.3	7.4	14.4	0.7	-3.8
Miserableness	1.3	2.2	2.4	-1.5	-1.4
Worry (Nagel 2018)	1.2	2.5	4.0	-2.0	-1.0
Mean Putamen Volume	1.2	1.3	2.4	1.6	-0.5
Maternal smoking around birth	1.2	1.7	2.9	1.7	-0.7
Happiness	1.2	1.5	2.1	-1.0	-1.4
Birth weight of first child	1.2	2.1	2.6	1.3	1.6
Number of full brothers	1.2	1.5	2.9	1.7	-0.2
Crohns Disease (2017)	1.1	2.4	3.5	1.1	-1.9
Chronic bronchitis/emphysema (father)	1.1	1.3	2.6	1.6	-0.1
Diabetes (self-reported)	1.1	1.8	3.5	-1.9	0.0
Number of children fathered	1.1	1.2	1.9	0.7	1.4
Emphysema/chronic bronchitis	1.1	1.2	2.3	1.5	-0.2
Alcohol intake frequency.	1.1	2.6	5.2	2.3	-0.2
Handedness (chirality/laterality): Left-handed	1.1	1.3	1.8	-0.9	-1.3
Diabetes diagnosed by doctor	1.1	1.7	3.5	-1.9	0.1
Pain type(s) experienced in last month: Hip pain	1.1	1.4	1.6	1.1	-1.3
Pain experienced in last month	1.1	1.8	3.5	-0.4	1.9
Alcohol drinker status: Previous	1.1	1.2	2.3	0.3	-1.5
Bipolar Disorder (2011)	1.0	1.0	1.1	-1.0	0.9
Chronotype (morning person)	1.0	2.2	2.6	1.4	-1.6
Serious illness, injury or assault to yourself	1.0	1.2	1.3	1.0	-1.1
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	1.9	-1.4	0.6
Hearing difficulty/problems with background noise	1.0	1.6	2.9	0.6	-1.7
Mouth/teeth dental problems: Dentures	1.0	1.7	3.3	-0.3	-1.8
Chronic bronchitis/emphysema (mother)	1.0	1.2	2.3	0.4	1.5
Knee pain experienced in last month	1.0	1.5	1.6	-1.2	-1.3
Illnesses of father: None of the above (group 1)	1.0	1.2	2.0	-0.7	-1.4
Risk taking	1.0	1.5	3.0	-1.7	-0.1
Irritable Bowel Disease (IBD)	0.9	2.1	2.4	1.4	-1.6
Medication: Metformin	0.9	1.3	1.4	-1.2	-1.1
Qualifications: CSEs or equivalent	0.9	1.1	2.1	1.5	-0.4
Alcohol usually taken with meals	0.9	1.4	1.7	1.3	-1.1
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	1.8	0.6	-1.4
Financial difficulties in last 2 years	0.9	1.2	1.3	-1.1	-1.2
Mouth/teeth dental problems	0.9	1.4	2.5	0.5	1.6
Allergy	0.9	2.0	2.4	-1.2	-1.6
Neuroticism score	0.9	1.8	2.4	-1.6	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	1.6	0.6	-1.3
Illnesses of mother	0.9	1.1	1.6	0.8	1.3
Leg fat percentage (right)	0.9	3.2	5.1	1.1	2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	1.3	-0.9	1.1
Commuting to job workplace: Car/motor vehicle	0.9	1.1	2.1	-0.2	1.4
Illnesses of father: Heart disease	0.9	1.2	1.8	1.3	0.8
Wears glasses or contact lenses	0.9	1.0	2.0	-0.3	1.4
Reaction Time	0.8	1.6	1.9	1.1	-1.4
Body Mass Index (BMI) (2010)	0.8	1.0	1.9	1.4	-0.4
Crohns Disease (2012)	0.8	1.2	2.4	0.1	-1.6
Neuroticism (2016)	0.8	1.1	2.2	-0.2	-1.5
Primary Biliary Cirrhosis	0.8	1.2	2.3	0.2	-1.5
Height	0.8	15.0	29.2	0.9	-5.4
Systolic Blood Pressure	0.8	4.2	8.5	-2.9	-0.0
Impedance of leg (right)	0.8	3.8	7.7	-0.1	2.8
Stomach or abdominal pain in last month	0.8	0.9	1.2	1.1	-0.8
Asthma	0.8	1.5	2.3	1.5	0.9
Glaucoma (self-reported)	0.8	1.0	1.3	-0.8	1.1
Health satisfaction	0.8	1.1	1.7	1.3	0.7
Leg fat-free mass (right)	0.8	4.4	7.5	1.2	-2.7
Asthma (self-reported)	0.8	1.6	2.6	1.6	0.8
Leg predicted mass (right)	0.8	4.3	7.2	1.2	-2.7
Average weekly champagne plus white wine intake	0.8	1.1	2.0	0.5	-1.4
Medication: Blood pressure	0.8	1.4	1.5	-1.2	-1.2
Leg fat percentage (left)	0.8	3.0	4.1	1.4	2.0
Number of operations (self-reported)	0.8	1.3	2.5	0.1	1.6
Depressed Affect (Nagel 2018)	0.7	1.4	2.8	-0.0	-1.7
Major Depression (MDD)	0.7	0.8	1.0	-1.0	-0.8
Breast Cancer	0.7	1.7	3.4	1.8	0.2
HDL Cholesterol	0.7	1.2	2.4	1.6	0.1
Blood White Count	0.7	4.9	5.8	-2.0	2.4
Sensitivity / hurt feelings	0.7	1.2	1.3	-1.1	-1.0
Systolic blood pressure, automated reading	0.7	1.9	3.8	-1.9	-0.3
Fed-up feelings	0.7	1.3	2.4	1.6	-0.5
High blood pressure	0.7	2.1	2.7	-1.2	-1.6
Impedance of leg (left)	0.7	3.5	6.7	0.5	2.6
Number of incorrect matches in round	0.7	1.1	2.0	-1.4	0.5
Alcohol intake versus 10 years previously	0.7	1.0	1.3	1.2	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	2.4	-0.2	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	1.9	-1.4	0.6
Pulse wave reflection index	0.7	0.8	1.6	-1.3	0.1
Medication: Blood pressure	0.7	1.3	1.8	-0.9	-1.3
Pulse rate, automated reading	0.7	2.3	2.9	1.7	-1.3
Hypertension (Self-reported)	0.7	2.1	2.6	-1.2	-1.6
Qualifications: nursing, teaching	0.7	1.1	1.5	-1.2	0.9
Mother’s age at death	0.7	0.9	1.4	-0.6	1.2
Ever depressed for a whole week	0.7	0.8	1.6	-0.3	-1.3
Basal cell carcinoma (self-reported)	0.7	0.8	1.1	-1.0	0.8
Deep venous thrombosis (DVT) (self-reported)	0.7	0.8	1.6	-0.3	1.3
Arm predicted mass (left)	0.7	3.3	4.5	1.5	-2.1
Coronary Artery Disease (CAD)	0.6	0.7	1.2	-0.5	-1.1
Average weekly spirits intake	0.6	0.7	1.2	-0.5	-1.1
Hearing difficulty/problems: Yes	0.6	0.8	1.5	1.2	-0.4
Medication: Co-codamol	0.6	0.7	1.3	1.1	0.3
Leg fat-free mass (left)	0.6	3.0	5.2	0.9	-2.3
Average weekly fortified wine intake	0.6	0.7	1.1	1.0	0.5
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.1	0.6	1.5
Worrier / anxious feelings	0.6	1.2	1.4	-0.9	-1.2
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	3.5	0.5	-1.9
Lung cancer (father)	0.6	0.7	0.8	0.9	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	3.4	0.4	-1.8
Wheeze or whistling in the chest in last year	0.6	1.1	2.1	1.4	-0.3
Migraine (self-reported)	0.6	0.8	1.6	-1.3	-0.0
Arm predicted mass (right)	0.6	3.1	3.9	1.5	-2.0
Overall health rating	0.6	1.4	1.6	1.3	1.0
Medication: Aspirin	0.6	0.8	1.5	-0.4	1.2
Whole body fat-free mass	0.6	3.2	5.7	0.8	-2.4
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	1.3	0.8	1.1
Whole body water mass	0.6	3.2	5.6	0.9	-2.4
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.6	0.2	-1.3
Arm fat-free mass (left)	0.6	2.8	4.0	1.3	-2.0
Bipolar Disorder (2018)	0.5	0.9	1.7	1.3	-0.0
Verbal and Numeric Reasoning (VNR)	0.5	1.2	2.3	-0.4	-1.5
Age at First Birth	0.5	0.7	1.0	0.6	-1.0
Triglycerides	0.5	0.8	1.1	-1.1	0.6
Heel T-Score	0.5	4.0	6.1	-1.4	2.5
BMI	0.5	3.0	5.3	2.3	-0.8
Allergy or Eczema	0.5	1.4	2.7	-0.1	1.6
Ever used hormone-replacement therapy (HRT)	0.5	0.6	0.8	0.9	0.6
Leg predicted mass (left)	0.5	2.9	5.0	0.8	-2.2
Past tobacco smoking	0.5	0.9	1.1	0.9	1.1
Nervous feelings	0.5	1.0	1.8	-0.3	-1.4
Hair/balding pattern: Pattern 2	0.5	0.6	1.2	-1.1	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.1	-1.4	0.2
Heart attack	0.5	0.6	0.9	0.9	0.5
Illnesses of siblings	0.5	0.7	0.8	-0.9	0.8
Pulse rate	0.5	0.9	1.4	1.2	-0.6
Trunk predicted mass	0.5	2.6	5.0	0.4	-2.2
Length of working week for main job	0.5	0.6	1.1	1.1	0.2
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.4	0.4	1.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.4	-0.1	-1.2
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.1	0.7	1.0
Body fat percentage	0.5	1.8	3.0	1.7	0.8
Arm fat-free mass (right)	0.5	2.5	3.3	1.3	-1.8
Age at first live birth	0.5	1.0	1.9	0.2	-1.4
Pulse wave peak to peak time	0.5	0.6	1.1	-0.2	-1.0
Medication: Omeprazole	0.5	0.6	0.8	-0.6	-0.9
Medication: Aspirin	0.5	0.6	1.2	-0.2	1.1
Smoking status: Current	0.5	0.7	1.3	-0.4	-1.1
Number of self-reported non-cancer illnesses	0.5	0.8	1.5	-0.4	1.2
Eye problems/disorders: Glaucoma	0.5	0.5	1.0	-1.0	0.3
High cholesterol (Self-reported)	0.5	0.8	1.5	0.4	1.2
Basal metabolic rate	0.5	2.8	4.7	1.0	-2.2
Unable to work because of sickness or disability	0.5	0.7	1.3	-1.1	-0.1
Vascular/heart problems diagnosed by doctor	0.5	1.4	1.7	1.3	1.1
Supplements: Calcium	0.5	0.5	0.9	-0.9	0.4
Heart attack/myocardial infarction (self-reported)	0.5	0.6	0.9	0.9	0.6
Lung FVC	0.4	2.2	3.5	1.0	1.9
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	1.1	-0.1	-1.1
Supplements: Zinc	0.4	0.5	0.8	0.4	0.9
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	0.8	-0.9	-0.2
Weight	0.4	1.8	2.2	1.5	-1.1
Trunk fat-free mass	0.4	2.4	4.7	0.4	-2.2
Standing height	0.4	4.2	7.8	0.7	-2.8
Blood clot in the leg (DVT)	0.4	0.5	0.9	0.3	1.0
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.6	0.6	0.8
Leg fat mass (right)	0.4	1.6	2.3	1.5	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	1.8	-1.3	0.2
Ever taken oral contraceptive pill	0.4	0.4	0.6	-0.4	0.8
Commuting to job workplace: Cycle	0.4	0.5	0.7	0.8	-0.5
Pack years of smoking	0.4	0.7	0.7	-0.8	0.8
Leg fat mass (left)	0.4	1.6	2.7	1.6	0.7
Bipolar Disorder or Schizophrenia	0.3	0.7	1.5	1.2	0.1
Ulcerative Colitis (UC)	0.3	0.6	0.8	0.9	-0.6
Respiratory disease	0.3	0.7	1.3	0.2	1.1
Medication for hormone replacement therapy	0.3	0.4	0.7	0.8	-0.2
Trunk fat percentage	0.3	1.3	2.5	1.6	0.1
Supplements: Glucosamine	0.3	0.4	0.8	0.9	-0.1
Sitting height	0.3	2.1	2.8	1.2	-1.7
Trunk fat mass	0.3	1.3	2.4	1.6	-0.3
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.6	0.8	0.5
Father’s age at death	0.3	0.4	0.6	-0.8	0.4
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.2	-1.1	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.6	0.8	-0.4
Prospective memory result	0.3	0.4	0.7	0.9	-0.2
Arm fat mass (right)	0.3	1.2	1.9	1.4	-0.6
Hair/balding pattern: Pattern 4	0.3	0.8	0.9	0.9	-0.9
Peak expiratory flow (PEF)	0.3	0.7	0.9	0.6	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.6	0.8	-0.4
Gout (self-reported)	0.3	0.4	0.6	0.8	-0.4
Medication: Allopurinol	0.3	0.5	0.8	0.9	-0.3
Medication: Seretide 50 evohaler	0.3	0.4	0.5	-0.4	0.7
Whole body fat mass	0.3	1.4	2.8	1.7	-0.3
Chest pain or discomfort	0.3	0.4	0.8	0.9	0.3
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.7	-0.1	0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	0.9	-0.6	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.4	0.6	0.4
Friendships satisfaction	0.3	0.4	0.7	-0.8	-0.2
Commuting to job workplace: Walk	0.3	0.3	0.5	0.7	-0.4
Mineral and other dietary supplements	0.3	0.5	0.8	-0.4	0.9
Medication: Bendroflumethiazide	0.3	0.4	0.8	0.3	-0.9
Illnesses of father: High blood pressure	0.3	0.4	0.4	-0.6	-0.6
Ever smoked	0.3	0.6	0.8	-0.9	-0.6
Age started oral contraceptive pill	0.3	0.4	0.8	0.9	0.1
Depression (Nagel 2018)	0.2	0.3	0.5	-0.7	-0.3
Intelligence (Savage-Jansen 2018)	0.2	0.5	0.5	0.7	-0.7
Alzheimer’s Disease (in mother)	0.2	0.2	0.3	-0.6	0.2
Alzheimer’s Disease (in father)	0.2	0.2	0.3	0.4	0.5
Ovarian Cancer	0.2	0.2	0.3	-0.5	0.4
Blood Platelet Count	0.2	2.6	4.0	-2.0	1.1
Smoking Status	0.2	0.5	1.0	-0.2	-1.0
Cardiovascular Disease	0.2	0.6	1.2	-1.1	-0.3
Hair Pigment	0.2	7.0	12.9	1.1	3.6
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.4	-0.4	-0.6
Ever had hysterectomy (womb removed)	0.2	0.2	0.4	-0.6	-0.2
Angina	0.2	0.2	0.2	-0.5	0.5
Severe depression (siblings)	0.2	0.3	0.3	0.5	0.6
Pack years adult smoking proportion	0.2	0.4	0.5	-0.5	0.7
Townsend deprivation index at recruitment	0.2	0.2	0.3	0.4	0.5
Current tobacco smoking	0.2	0.4	0.7	-0.2	-0.8
Taking other prescription medications	0.2	0.2	0.5	-0.1	0.7
Body mass index (BMI)	0.2	0.7	1.4	1.2	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.6	-0.1	0.8
Forced vital capacity (FVC)	0.2	0.9	1.3	1.1	-0.8
Pain all over the body in last month	0.2	0.3	0.3	-0.4	-0.6
Medication: Simvastatin	0.2	0.2	0.4	-0.3	-0.6
Arm fat percentage (right)	0.2	0.8	1.5	1.2	0.3
Hip circumference	0.2	0.7	1.3	1.1	0.2
Hair/balding pattern: Pattern 3	0.2	0.3	0.4	0.7	0.3
Medication: Cholesterol lowering	0.2	0.4	0.7	-0.0	-0.9
Pulse wave Arterial Stiffness index	0.2	0.3	0.4	0.3	0.7
Medication: Paracetamol	0.2	0.4	0.8	-0.9	-0.1
Medication: Amlodipine	0.2	0.3	0.5	0.7	0.3
Birth weight	0.2	0.5	1.0	-1.0	0.2
Comparative body size at age 10	0.2	0.6	0.6	0.7	-0.8
Qualifications: College or University degree	0.2	0.7	1.0	-1.0	0.7
Eye problems/disorders: None of the above	0.2	0.3	0.4	-0.4	-0.6
Angina (self-reported)	0.2	0.3	0.5	-0.7	0.4
Mean time to correctly identify matches	0.2	0.4	0.6	-0.4	-0.8
Heart disease (mother)	0.2	0.2	0.4	0.6	0.1
Arm fat percentage (left)	0.2	0.9	1.5	1.2	0.6
Average weekly red wine intake	0.2	0.2	0.4	0.6	0.3
Mood swings	0.2	0.3	0.5	0.3	-0.7
Ever had bowel cancer screening	0.2	0.2	0.2	-0.5	-0.4
Eye problems/disorders: Cataract	0.2	0.2	0.4	0.4	0.6
Breast cancer (self-reported)	0.2	0.2	0.4	-0.6	0.1
Medication: Gliclazide	0.2	0.2	0.2	-0.5	-0.4
Arm fat mass (left)	0.2	1.0	1.8	1.3	-0.5
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.3	0.6	0.2
Commuting to job workplace: Public transport	0.2	0.2	0.3	-0.1	-0.6
Medication: Paracetamol	0.2	0.3	0.5	0.3	-0.7
Medication: Atorvastatin	0.2	0.3	0.6	-0.2	0.8
Fractured/broken bones in last 5 years	0.2	0.3	0.5	0.4	0.7
Diastolic blood pressure, automated reading	0.2	0.6	0.8	0.6	0.9
Impedance of whole body	0.2	0.9	1.8	0.3	1.3
Schizophrenia (2018)	0.1	0.1	0.2	0.5	0.2
Schizophrenia vs Biploar Disorder	0.1	0.1	0.2	-0.4	-0.3
Rheumatoid Arthritis	0.1	0.1	0.2	-0.3	-0.5
Schizophrenia (2014)	0.1	0.2	0.3	0.3	0.6
Ulcerative Colitis	0.1	0.1	0.1	-0.2	-0.4
Blood Eosinophil Count	0.1	0.4	0.8	0.2	-0.9
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.3	0.5	-0.1
Hand grip strength (right)	0.1	0.3	0.4	-0.4	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.4	-0.6	0.1
Waist circumference	0.1	0.4	0.8	0.9	0.3
Forced vital capacity (FVC), Best measure	0.1	0.4	0.5	0.7	-0.6
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.3	0.5	-0.2
Age at last live birth	0.1	0.2	0.3	0.0	-0.6
Family relationship satisfaction	0.1	0.1	0.1	-0.4	-0.2
Leg pain on walking	0.1	0.1	0.1	-0.4	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	0.3	-0.4
Illnesses of siblings: Diabetes	0.1	0.1	0.3	0.5	0.1
Smoking status: Previous	0.1	0.2	0.4	-0.6	-0.2
Loneliness, isolation	0.1	0.1	0.1	0.3	-0.2
Long-standing illness, disability or infirmity	0.1	0.1	0.1	0.4	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.2	-0.5	-0.2
Back pain experienced in last month	0.1	0.1	0.2	0.1	-0.5
Osteoporosis (self-reported)	0.1	0.1	0.2	-0.2	-0.4
Osteoarthritis (self-reported)	0.1	0.1	0.2	-0.5	0.2
Irritability	0.1	0.2	0.3	-0.6	0.3
Cholesterol lowering medication	0.1	0.2	0.2	-0.3	0.5
Heart disease (siblings)	0.1	0.1	0.2	0.5	-0.1
Alzheimer’s Disease (including proxy)	0.0	0.0	0.0	0.1	0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.1	0.2	0.1	-0.4
Waist Hip Ratio (WHR)	0.0	0.0	0.1	0.1	-0.3
Tanning	0.0	0.1	0.1	-0.3	-0.3
Hand grip strength (left)	0.0	0.0	0.1	-0.2	0.1
Number of treatments/medications taken	0.0	0.0	0.1	0.1	-0.2
Relative age of first facial hair	0.0	0.0	0.0	0.1	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.0	0.0	0.1	0.0
Relative age voice broke	0.0	0.1	0.1	-0.3	0.1
Qualifications: None of the above	0.0	0.0	0.0	-0.0	-0.2
Impedance of arm (right)	0.0	0.0	0.1	-0.3	0.0
Time employed in main current job	0.0	0.0	0.0	-0.1	0.2
Falls in the last year	0.0	0.0	0.0	0.1	0.2
Impedance of arm (left)	0.0	0.2	0.3	-0.6	0.4
Headache pain in last month	0.0	0.0	0.1	0.3	-0.0
Exposure to tobacco smoke outside home	0.0	0.0	0.0	-0.1	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.0	0.1	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	0.2	0.1
Medication for cholesterol	0.0	0.0	0.0	0.2	-0.2

Hub : Genes

NCBP1

Models

Trait associations