Best TWAS P=1.27e-10 · Best GWAS P=5.66e-15 conditioned to 1e-13
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 0.0008 | 5.4 | -5.4 | 8.5e-08 | -0.14 | 0.01 | 0.98 | FALSE |
2 | GTEx | Spleen | MLLT10 | 0.16 | 0.02 | lasso | 7 | 0.02 | 0.1030 | 5.6 | -6.0 | 1.9e-09 | -0.15 | 0.03 | 0.56 | FALSE |
3 | YFS | Blood | MLLT10 | 0.02 | 0.01 | bslmm | 298 | 0.01 | 0.0021 | 3.3 | -6.4 | 1.3e-10 | -0.06 | 0.08 | 0.08 | TRUE |