TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Lung FEV1/FVC ratio
:
←
→
chr10:21,123,825-22,724,472
Best TWAS P=1.27e-10 · Best GWAS P=5.66e-15 conditioned to 1e-13
21.2M
21.4M
21.6M
21.8M
22M
22.2M
22.4M
22.6M
22.8M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
YFS
Blood
MLLT10
0.02
0.01
bslmm
298
0.01
0.0021
3.3
-6.4
1.3e-10
-0.06
0.08
0.08
TRUE
2
GTEx
Spleen
MLLT10
0.16
0.02
lasso
7
0.02
0.1030
5.6
-6.0
1.9e-09
-0.15
0.03
0.56
FALSE
1
GTEx
Skin Sun Exposed Lower leg
MLLT10
0.06
0.02
lasso
4
0.03
0.0008
5.4
-5.4
8.5e-08
-0.14
0.01
0.98
FALSE