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Lung FEV1/FVC ratio
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chr10:95,606,207-97,070,115
Best TWAS P=1.44e-08 · Best GWAS P=8.31e-09 conditioned to 0.0308
95.6M
95.8M
96M
96.2M
96.4M
96.6M
96.8M
97M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Skin Sun Exposed Lower leg
HELLS
0.05
0.02
lasso
3
0.00
0.1150
4.5
5.7
1.4e-08
0.78
0.02
0.94
TRUE
3
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
NOC3L
0.03
0.01
blup
47
0.02
0.0026
-3.5
5.4
6.9e-08
0.49
0.02
0.05
FALSE
2
ROSMAP
Brain Pre-frontal Cortex
HELLS
0.02
0.01
blup
372
0.00
0.0688
4.6
5.1
2.8e-07
0.63
0.21
0.60
FALSE