Best TWAS P=1.44e-08 · Best GWAS P=8.31e-09 conditioned to 0.0308
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | HELLS | 0.05 | 0.02 | lasso | 3 | 0.00 | 0.1150 | 4.5 | 5.7 | 1.4e-08 | 0.78 | 0.02 | 0.94 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | HELLS | 0.02 | 0.01 | blup | 372 | 0.00 | 0.0688 | 4.6 | 5.1 | 2.8e-07 | 0.63 | 0.21 | 0.60 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | NOC3L | 0.03 | 0.01 | blup | 47 | 0.02 | 0.0026 | -3.5 | 5.4 | 6.9e-08 | 0.49 | 0.02 | 0.05 | FALSE |