Best TWAS P=2.41e-08 · Best GWAS P=1.54e-11 conditioned to 0.000298
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TMEM180 | 0.21 | 0.07 | lasso | 6 | 0.14 | 1.9e-16 | -3.5 | -5.6 | 2.4e-08 | 0.73 | 0.01 | 0.99 | TRUE |
2 | GTEx | Liver | ACTR1A | 0.15 | 0.00 | lasso | 10 | 0.00 | 4.6e-01 | -3.6 | -5.2 | 1.9e-07 | 0.04 | 0.07 | 0.08 | TRUE |