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Traits
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Lung FEV1/FVC ratio
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chr10:103,527,782-104,956,035
Best TWAS P=2.41e-08 · Best GWAS P=1.54e-11 conditioned to 0.000298
103.6M
103.8M
104M
104.2M
104.4M
104.6M
104.8M
105M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
TMEM180
0.21
0.07
lasso
6
0.14
1.9e-16
-3.5
-5.6
2.4e-08
0.73
0.01
0.99
TRUE
2
GTEx
Liver
ACTR1A
0.15
0.00
lasso
10
0.00
4.6e-01
-3.6
-5.2
1.9e-07
0.04
0.07
0.08
TRUE