TWAS
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Traits
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Lung FEV1/FVC ratio
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chr10:120,269,685-121,907,055
Best TWAS P=3.72e-08 · Best GWAS P=2.57e-08 conditioned to 6.81e-08
120.2M
120.4M
120.6M
120.8M
121M
121.2M
121.4M
121.6M
121.8M
122M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
GRK5
0.12
0.03
lasso
8
0.06
1e-08
-3.4
5.5
3.7e-08
-0.03
0.68
0.2
TRUE