[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr11:198,510-1,479,601

Best TWAS P=1.44e-10 · Best GWAS P=2e-08 conditioned to 0.848

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	NTR	Blood	IFITM3	0.19	0.10	bslmm	303	0.12	9.4e-38	-5.6	-6.4	1.4e-10	0.87	0.00	1.00	TRUE
8	The Cancer Genome Atlas	Lung Adenocarcinoma	TSPAN4	0.09	0.04	enet	9	0.03	1.9e-04	4.6	5.7	1.2e-08	-0.02	0.00	0.95	TRUE
9	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IFITM3	0.04	0.01	lasso	4	0.01	1.2e-02	-5.3	-5.8	8.6e-09	0.68	0.01	0.77	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	IFITM3	0.08	0.01	enet	16	0.03	3.8e-04	-2.9	-5.5	4.5e-08	0.44	0.02	0.55	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	IFITM3	0.10	0.10	lasso	3	0.11	1.6e-21	4.7	-5.4	5.6e-08	0.60	0.11	0.89	FALSE
1	GTEx	Brain Cerebellar Hemisphere	AP006621.5	0.52	0.14	enet	38	0.13	3.6e-04	3.9	5.3	1.1e-07	-0.02	0.15	0.22	FALSE
2	GTEx	Whole Blood	IFITM3	0.09	0.02	enet	12	0.07	5.2e-07	-4.0	-5.3	1.1e-07	0.62	0.02	0.92	FALSE
5	ROSMAP	Brain Pre-frontal Cortex	RP11-326C3.7	0.07	0.06	lasso	2	0.04	2.9e-06	-5.3	5.3	1.5e-07	-0.67	0.01	0.99	FALSE
4	ROSMAP	Brain Pre-frontal Cortex	IFITM3	0.10	0.06	lasso	5	0.08	1.1e-10	4.7	-5.2	2.1e-07	0.53	0.03	0.97	FALSE
6	YFS	Blood	IFITM3	0.70	0.26	enet	78	0.43	2.0e-158	-5.6	-5.2	2.1e-07	0.72	0.00	1.00	FALSE