TWAS hub - IFITM3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Whole Blood	0.0930	0.0400	7.0e-03	0.024	NA	0.070	NA	0.069	2.4e-03	NA	5.2e-07	NA	5.7e-07
2	METSIM	Adipose	0.1477	0.0416	1.3e-05	0.092	0.040	0.077	0.076	0.084	1.1e-13	1.0e-06	1.2e-11	1.5e-11	1.3e-12
3	NTR	Blood	0.1878	0.0280	0.0e+00	0.099	0.117	0.121	0.124	0.117	2.3e-30	8.3e-36	8.6e-37	9.4e-38	1.1e-35
4	ROSMAP	Brain Pre-frontal Cortex	0.1014	0.0326	4.5e-04	0.058	0.036	0.072	0.056	0.082	6.3e-08	1.6e-05	1.5e-09	9.8e-08	1.1e-10
5	YFS	Blood	0.6959	0.0233	0.0e+00	0.261	0.222	0.434	0.157	0.189	4.0e-85	3.8e-71	2.0e-158	6.4e-49	1.7e-59
6	TCGA	Breast Invasive Carcinoma	0.1012	0.0249	5.6e-17	0.100	0.098	0.100	NA	0.109	1.0e-19	1.9e-19	8.8e-20	NA	1.6e-21
7	TCGA	Colon Adenocarcinoma	0.1040	0.0440	3.6e-03	0.028	0.023	0.002	NA	0.007	9.6e-03	1.8e-02	2.4e-01	NA	1.1e-01
8	TCGA	Esophageal Carcinoma	0.1450	0.0600	4.8e-03	0.070	0.049	0.038	NA	0.087	3.0e-03	1.1e-02	2.3e-02	NA	1.0e-03
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0418	0.0192	5.5e-03	0.015	0.017	0.004	NA	0.015	6.6e-03	4.7e-03	1.0e-01	NA	7.6e-03
10	TCGA	Brain Lower Grade Glioma	0.0616	0.0233	1.8e-04	0.015	0.032	0.027	NA	0.024	7.0e-03	1.2e-04	4.7e-04	NA	8.7e-04
11	TCGA	Lung Squamous Cell Carcinoma	0.0386	0.0166	3.2e-03	0.008	0.012	0.004	NA	0.013	3.8e-02	1.4e-02	1.1e-01	NA	1.2e-02
12	TCGA	Prostate Adenocarcinoma	0.1385	0.0354	2.7e-10	0.091	0.067	0.120	NA	0.109	8.3e-10	1.5e-07	1.7e-12	NA	1.9e-11
13	TCGA	Thyroid Carcinoma	0.0840	0.0290	1.6e-04	0.008	0.032	0.032	NA	0.028	5.5e-02	3.9e-04	3.8e-04	NA	8.4e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Blood White Count	19.6	145.4	243.4	15.6	12.7	12.9	12.2	11.4	13.3	10.2	6.1	13.4	11.6	11.3	11.8	11.9
Eye problems/disorders: Cataract	7.5	8.7	13.2	3.1	3.5	3.3	3.2	3.6	3.6	2.6	0.8	2.8	2.0	3.3	2.8	2.6
Eye problems/disorders: None of the above	6.4	7.4	15.6	-2.8	-2.9	-4.0	-2.7	-3.8	-3.3	-2.5	-1.0	-2.5	-1.8	-2.4	-2.6	-1.8
Mouth/teeth dental problems: Mouth ulcers	5.8	9.2	19.0	-2.8	-2.6	-2.9	-3.3	-3.1	-3.0	-1.5	-1.8	-2.8	-3.6	-3.0	-3.5	-4.4
Hypothyroidism/myxoedema (self-reported)	5.4	10.6	18.7	-3.4	-2.1	-3.0	-3.9	-3.6	-3.4	-4.3	-1.5	-2.6	-3.0	-4.3	-4.2	0.4
Lung FEV1/FVC ratio	5.2	26.2	41.1	-5.3	-4.8	-6.4	-5.2	-5.2	-5.4	-4.3	-3.5	-5.0	-4.4	-5.8	-5.1	-5.5
Hypothyroidism (self reported)	5.0	11.4	21.7	-3.2	-2.2	-3.9	-3.9	-4.5	-3.7	-4.7	-0.4	-2.3	-2.3	-4.1	-4.3	0.7
Blood Platelet Count	4.4	51.6	185.0	-4.5	-6.3	-2.2	-7.0	0.1	-4.7	-13.6	-8.1	-9.6	3.2	-9.7	-8.2	-4.5
Medication: Allopurinol	4.1	5.5	10.6	-2.6	-1.9	-1.7	-2.6	-1.1	-1.9	-1.3	-2.9	-2.2	-2.8	-2.6	-2.5	-3.3
Pulse wave Arterial Stiffness index	4.0	4.6	8.9	2.4	1.8	3.0	2.2	2.4	1.9	1.9	1.2	2.1	2.2	1.8	2.6	2.0
Relative age of first facial hair	3.9	8.0	12.7	-2.6	-3.6	-2.8	-3.5	-2.3	-3.5	-2.8	-1.8	-1.9	-2.2	-3.1	-2.8	-3.1
Pulse wave peak to peak time	3.6	4.2	7.5	-2.4	-1.7	-2.7	-2.2	-2.1	-1.9	-1.9	-0.9	-1.9	-2.0	-1.9	-2.6	-1.8
Primary Biliary Cirrhosis	3.3	4.7	15.5	-2.8	-3.7	-3.6	-3.9	-3.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Commuting to job workplace: Cycle	3.2	3.9	6.8	-1.5	-1.6	-1.4	-2.4	-1.6	-1.8	-1.8	-2.6	-2.0	-2.6	-2.2	-2.3	-1.3
Gout (self-reported)	3.1	4.3	10.0	-1.2	-1.6	-1.5	-2.6	-1.1	-1.5	-1.2	-2.8	-2.1	-3.2	-1.5	-2.3	-2.7
Breast Cancer	2.9	6.9	13.6	2.0	2.8	3.7	3.0	2.0	3.0	3.1	1.1	2.6	1.7	2.6	2.8	2.5
Heel bone mineral density (BMD) T-score, automated (left)	2.9	6.7	15.1	2.8	1.9	3.0	2.9	3.0	2.6	2.1	1.0	1.6	2.2	3.9	3.4	1.5
Mouth/teeth dental problems	2.9	4.4	7.3	1.7	1.8	2.7	2.3	2.7	2.2	1.2	1.3	0.8	2.4	2.6	2.5	1.9
Financial situation satisfaction	2.9	3.6	8.1	-2.0	-0.5	-2.2	-1.3	-1.6	-1.5	-2.9	-0.4	-2.7	-2.2	-2.3	-2.1	-0.6
Ovarian Cancer	2.8	3.7	6.4	1.4	1.6	1.9	2.0	1.8	1.8	2.4	2.5	2.3	2.1	1.8	1.9	0.6
Heart attack	2.8	3.5	8.7	2.9	1.5	1.5	2.0	1.2	1.6	1.4	1.6	2.2	1.8	0.8	1.7	2.9
Medication: Levothyroxine sodium	2.6	4.4	11.7	-2.1	-1.3	-1.7	-2.4	-2.5	-2.3	-2.8	-0.1	-1.1	-1.5	-3.4	-2.6	0.8
Crohns Disease (2017)	2.5	5.5	18.8	2.6	1.2	4.3	2.0	3.8	2.1	0.5	-0.6	1.4	1.2	3.4	2.3	1.2
Sensitivity / hurt feelings	2.5	4.2	7.5	1.1	2.4	2.0	2.7	1.5	2.4	2.7	1.9	2.6	2.2	1.1	2.1	0.4
Blood Eosinophil Count	2.3	18.1	83.5	6.2	2.7	1.6	0.9	0.4	1.1	-2.2	3.7	8.2	4.1	0.1	-0.4	9.1
Blood Red Count	2.3	21.8	45.7	6.2	4.7	3.4	4.8	3.8	5.0	5.4	1.3	6.8	5.4	3.2	4.0	4.2
Maternal smoking around birth	2.3	3.4	9.1	-0.0	-3.0	-0.3	-2.8	-1.6	-2.7	-1.2	-2.0	-0.8	-1.8	-1.1	-2.2	1.1
Heel bone mineral density (BMD) T-score, automated (right)	2.3	5.4	11.4	2.4	2.0	2.8	2.6	3.1	2.6	1.7	1.0	1.1	2.1	3.4	2.6	1.2
Qualifications: A levels/AS levels or equivalent	2.3	5.0	11.8	1.3	2.0	0.9	2.8	1.5	1.8	3.4	2.6	1.7	3.4	1.5	3.0	-0.8
Heart attack/myocardial infarction (self-reported)	2.3	3.0	7.8	2.5	1.6	1.4	1.9	1.2	1.6	1.2	1.5	1.9	1.8	0.5	1.6	2.8
Taking other prescription medications	2.2	3.5	7.6	-0.8	-2.3	-0.6	-2.5	-1.7	-2.8	-2.4	-1.1	-1.6	-1.4	-2.3	-2.1	-0.7
Time employed in main current job	2.2	2.5	6.8	2.6	0.3	1.9	1.1	2.0	1.0	2.2	0.9	1.7	1.0	1.7	1.7	-0.4
Waist Hip Ratio (WHR)	2.1	9.7	15.1	1.5	3.5	3.4	3.1	2.8	3.4	3.9	2.0	3.4	3.7	3.0	3.2	2.6
Average weekly spirits intake	2.0	2.5	5.4	1.2	1.9	1.2	1.8	0.4	1.5	1.1	2.3	1.7	1.9	0.6	1.5	2.2
Pulse rate	2.0	3.4	7.1	1.0	2.3	1.1	2.7	1.4	2.0	1.6	1.4	2.0	2.4	1.5	2.3	1.1
Alcohol drinker status: Previous	2.0	2.3	5.5	-0.3	-1.4	-1.5	-2.2	-1.5	-1.8	-1.6	-1.9	-0.2	-0.9	-1.6	-2.3	-0.1
Exposure to tobacco smoke outside home	1.9	2.5	5.4	1.1	2.3	1.6	2.0	1.2	2.3	1.6	1.2	0.7	0.7	2.2	1.7	0.7
Pulse rate, automated reading	1.9	6.1	9.4	1.9	2.5	2.9	2.7	2.2	2.5	2.1	1.7	2.3	2.6	2.5	2.8	3.1
Tinnitus: Yes, now most or all of the time	1.9	2.2	5.5	1.8	0.4	0.6	1.0	1.7	1.1	0.9	2.1	2.0	2.3	1.5	0.8	1.2
Heart disease (siblings)	1.9	2.4	4.9	2.2	1.0	1.2	2.0	1.1	1.3	2.0	2.0	1.3	1.6	1.0	1.7	0.4
Age when periods started (menarche)	1.8	4.2	7.8	-2.8	-2.1	-2.7	-2.2	-2.8	-2.5	-0.0	-0.8	-0.6	-1.7	-2.8	-1.9	-1.2
Risk taking	1.8	2.6	6.7	-1.8	-1.3	-2.4	-1.2	-2.6	-1.5	-2.3	0.2	-1.4	-1.1	-1.9	-1.1	-0.3
Breast cancer (self-reported)	1.7	2.0	4.3	-2.1	-1.7	-0.9	-1.1	-0.8	-1.6	-1.9	-1.1	-1.3	-0.7	-1.4	-1.1	-2.0
Chronic bronchitis/emphysema (mother)	1.6	1.8	5.2	1.6	1.5	0.7	1.2	0.0	1.3	0.8	0.6	1.4	1.9	0.6	1.7	2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	2.0	4.9	-1.3	-0.9	-1.7	-1.2	-2.0	-1.3	-1.3	0.1	0.1	-1.1	-2.2	-2.1	0.8
Heel T-Score	1.5	11.6	22.6	4.8	2.8	3.5	3.8	3.2	4.0	3.9	0.6	3.5	1.7	4.4	3.9	1.5
Other serious medical condition/disability diagnosed by doctor	1.5	2.0	4.1	-1.2	-1.4	-0.0	-1.6	-0.8	-1.4	-1.9	-1.0	-1.5	-1.4	-0.9	-1.9	-2.0
Illnesses of siblings	1.5	2.1	3.9	-1.9	-1.6	-0.5	-1.8	-1.4	-1.6	-1.4	-1.0	-1.1	-1.7	-1.2	-2.0	-0.4
Noisy workplace	1.5	1.8	3.2	-0.2	-1.6	-1.2	-1.6	-1.6	-1.4	-1.2	-0.8	-1.2	-0.8	-1.8	-1.3	-1.7
Comparative height size at age 10	1.5	8.2	13.2	2.2	3.2	3.6	3.0	2.8	3.0	2.1	2.2	3.0	3.0	2.8	2.5	3.5
Ever had bowel cancer screening	1.5	1.7	7.5	2.7	0.4	2.1	1.0	1.4	0.7	0.9	-0.5	0.8	0.7	0.9	1.9	0.7
Myopia	1.5	2.2	4.3	0.7	1.2	1.0	1.7	1.5	1.7	2.0	-0.3	2.1	0.5	1.8	1.7	1.8
Suffer from ‘nerves’	1.4	2.2	5.9	-1.8	-1.2	-1.5	-1.0	-1.3	-1.4	-0.3	-1.9	-2.4	-2.2	-1.0	-0.2	-1.3
Chest pain or discomfort	1.4	2.1	7.2	1.5	0.5	1.7	1.8	0.9	0.8	1.1	2.7	0.3	0.8	1.9	1.8	0.8
Alcohol drinker status: Never	1.4	1.7	5.7	1.2	0.4	0.8	1.3	1.0	0.8	1.9	2.4	1.2	1.5	1.3	0.9	1.2
Vitamin and mineral supplements	1.3	1.8	5.5	-2.4	-1.2	-1.6	-1.1	-1.3	-1.2	-1.5	-0.3	-1.4	-1.1	-1.5	-1.1	-1.0
Waist circumference	1.3	4.8	9.1	2.1	2.2	2.5	2.3	1.4	2.1	0.7	1.4	2.8	2.6	2.2	2.1	3.0
Hair/balding pattern: Pattern 2	1.3	1.6	4.0	-0.1	-2.0	-0.6	-1.4	-1.2	-1.5	-1.5	-0.8	-1.4	-1.5	-0.2	-1.1	-1.7
Length of working week for main job	1.3	1.4	5.9	-1.0	-0.7	-1.5	-1.1	-0.9	-1.4	-2.4	0.1	-1.5	-0.2	-1.3	-1.0	0.2
Worry too long after embarrassment	1.3	2.2	4.9	0.6	1.5	1.1	1.9	0.9	1.3	1.9	2.2	0.9	1.2	1.3	2.0	1.2
Handedness (chirality/laterality): Left-handed	1.3	1.6	4.5	-1.1	-2.0	-1.4	-1.9	-1.0	-2.1	-0.7	-0.4	-0.4	-0.6	-1.2	-1.4	-0.3
Illnesses of father: High blood pressure	1.3	1.6	4.2	-0.2	2.1	0.2	1.9	0.6	1.6	1.4	0.9	1.0	1.6	0.7	1.5	1.0
Alzheimer’s Disease (in father)	1.2	1.3	3.0	0.7	1.5	-0.0	1.2	0.0	1.6	1.4	1.7	1.0	0.8	1.3	1.0	0.5
Supplements: Zinc	1.2	1.3	2.7	0.5	1.1	0.9	1.3	1.3	1.2	1.6	1.6	0.7	1.4	1.1	0.9	-0.1
Hair/balding pattern: Pattern 3	1.2	1.8	4.6	0.3	1.3	0.8	2.1	1.8	1.5	1.6	1.9	1.1	1.4	0.3	1.1	0.2
Number of full brothers	1.2	1.5	4.2	2.0	0.3	2.0	0.6	0.4	0.6	0.5	1.5	0.3	1.6	1.5	1.0	1.6
Shortness of breath walking on level ground	1.2	1.5	7.9	0.3	0.7	1.2	1.1	1.0	0.7	0.3	2.8	-0.2	1.7	1.4	1.1	0.4
Osteoporosis (self-reported)	1.2	1.4	2.8	1.4	1.7	1.2	1.0	0.4	1.6	1.1	1.1	1.5	0.4	1.6	0.5	0.9
Supplements: Fish oil (including cod liver oil)	1.2	1.6	3.2	0.9	1.6	0.5	1.5	1.5	1.7	1.5	1.1	1.1	1.2	1.8	0.9	-0.1
Alzheimer’s Disease (in mother)	1.1	1.2	3.6	-1.9	-1.3	-0.5	-1.4	0.0	-1.5	-1.4	-0.3	-1.2	0.0	-0.5	-1.1	-1.2
Prostate Cancer	1.1	1.5	4.8	-1.7	-0.8	-0.1	-0.9	-0.7	-1.1	-0.8	-2.2	-2.0	-0.8	-1.8	-0.5	-0.7
Medication: Co-codamol	1.1	1.3	4.6	-0.1	-1.5	1.0	-0.6	0.4	-1.0	-1.2	-1.1	-1.9	-1.0	-0.4	-0.2	-2.1
Mouth/teeth dental problems: Dentures	1.1	1.8	4.4	0.5	-2.1	-1.4	-1.6	-1.4	-1.9	-1.5	0.6	-0.1	-0.4	-1.8	-1.7	-0.3
Breastfed as a baby	1.1	1.4	3.0	1.0	0.4	1.7	1.1	1.6	1.1	0.7	-0.3	0.5	1.7	1.7	1.0	-1.1
Hair/balding pattern: Pattern 4	1.1	2.6	3.7	1.8	1.9	1.9	1.8	1.4	1.9	1.1	0.6	1.4	1.2	1.8	1.9	1.7
Illnesses of siblings: Diabetes	1.1	1.4	3.7	1.9	1.5	0.3	1.2	0.5	1.1	0.5	0.6	0.8	1.2	1.0	1.9	1.3
Number of self-reported non-cancer illnesses	1.1	1.9	6.0	-0.2	-1.5	0.0	-1.5	-0.9	-1.9	-2.1	-0.1	-2.5	-0.8	-1.8	-1.2	-0.1
Number of operations (self-reported)	1.1	1.6	5.2	-0.9	-1.9	-1.1	-1.4	-1.0	-1.6	-0.7	0.6	-1.2	-0.8	-0.8	-1.3	-2.3
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	5.8	0.8	-0.2	0.8	0.9	1.2	0.3	0.6	1.2	1.6	2.4	0.2	1.1	0.5
Pain all over the body in last month	1.0	1.0	2.4	-1.2	-1.6	-0.7	-1.0	-0.5	-1.2	-1.1	0.9	-1.4	-0.4	0.1	-1.1	-1.1
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	4.6	2.1	1.3	1.0	1.3	0.7	1.2	-0.4	1.7	0.1	1.1	1.1	1.1	0.0
Medication: Ramipril	1.0	1.3	5.2	-0.6	-1.2	-2.3	-0.8	-1.1	-1.1	-1.6	0.7	-0.3	0.1	-1.1	-1.4	-0.9
Father’s age at death	1.0	1.4	3.2	0.8	1.2	0.6	1.1	1.0	1.6	1.8	0.7	1.1	0.7	1.5	1.5	0.8
Lung cancer (father)	1.0	1.2	3.1	0.9	1.2	0.9	1.2	1.2	1.4	1.8	0.8	1.2	0.7	0.8	1.1	0.1
Medication: Omeprazole	1.0	1.2	3.3	-0.4	-1.0	-0.8	-1.3	-1.1	-1.1	-1.8	-1.4	-1.1	-1.3	-0.8	-1.1	-0.4
Medication: Aspirin	1.0	1.3	3.3	0.8	1.4	0.8	1.3	0.7	1.2	0.8	1.3	0.9	1.4	0.3	1.4	1.8
Mineral and other dietary supplements	1.0	1.3	2.6	-0.4	-1.1	-0.6	-1.5	-1.3	-1.3	-1.3	-1.1	-0.8	-1.1	-1.6	-1.3	0.5
Commuting to job workplace: Public transport	1.0	1.2	7.2	-0.5	1.0	-0.1	1.5	0.2	0.5	0.5	2.7	0.5	1.6	-0.0	1.4	0.4
Fractured/broken bones in last 5 years	1.0	1.2	5.8	0.6	-0.5	-2.4	-1.3	-1.7	-0.7	-0.7	-0.8	-0.2	-1.1	-0.1	-1.3	-0.8
Nervous feelings	0.9	1.7	5.8	0.8	1.1	0.9	2.0	1.0	1.1	2.1	0.7	0.8	1.0	0.6	2.4	-0.0
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	3.9	-0.2	2.0	-0.2	1.1	-0.1	1.5	1.6	-0.7	1.8	0.2	0.5	0.8	0.6
Medication: Ventolin 100micrograms inhaler	0.9	1.2	3.2	1.6	1.0	-0.3	0.7	-0.4	0.5	0.0	1.6	1.7	1.0	0.9	0.3	1.8
Forced vital capacity (FVC), Best measure	0.9	3.2	9.1	2.1	1.1	1.9	1.6	1.6	1.8	2.0	0.7	1.4	1.3	3.0	2.2	1.3
Medication: Ibuprofen	0.9	1.1	3.0	-0.9	1.7	-0.2	1.1	0.3	1.3	1.6	-0.4	1.6	0.5	0.7	0.7	1.0
Medication: Paracetamol	0.9	1.4	3.7	1.3	1.2	0.5	1.9	0.9	1.3	1.0	1.2	0.7	0.8	1.4	1.7	-0.0
Ever depressed for a whole week	0.9	1.1	2.3	-0.9	-1.2	-0.7	-1.4	-0.7	-1.4	-0.8	-1.5	-0.8	-1.0	-0.9	-1.1	-0.1
Irritable Bowel Disease (IBD)	0.8	2.0	10.4	1.8	0.4	3.2	0.4	1.9	1.0	0.4	-1.4	0.4	-0.5	1.9	0.9	-0.3
Medication for hormone replacement therapy	0.8	0.9	2.9	-1.7	-1.1	-0.2	-0.7	-0.1	-1.3	0.0	1.6	-0.9	-0.1	-0.6	-0.9	-1.2
Trunk fat percentage	0.8	3.2	5.6	1.4	2.4	2.1	2.0	1.6	1.9	0.6	1.2	1.4	2.3	1.4	1.8	2.0
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	3.2	-0.9	-1.2	0.3	-0.3	-0.3	-0.9	-0.8	-0.9	-1.6	-0.8	-0.4	0.4	-1.8
Had menopause	0.8	1.0	3.0	-0.4	-1.6	-0.6	-1.0	-0.2	-1.3	0.2	-0.0	-1.0	-1.7	-0.7	-0.6	-1.6
Diabetes (self-reported)	0.8	1.2	2.9	-0.9	-1.4	-1.3	-1.3	-1.2	-1.7	-1.3	-0.3	-0.1	-0.1	-1.3	-1.1	0.6
Worrier / anxious feelings	0.8	1.6	3.4	1.6	1.7	0.5	1.6	1.1	1.3	1.8	1.2	1.4	1.0	0.6	1.0	-0.1
Number of live births	0.8	1.1	2.3	0.4	-1.4	-1.3	-1.1	-1.5	-1.1	-0.9	1.0	-0.5	-0.2	-1.1	-1.1	-0.9
Birth weight of first child	0.8	1.5	5.6	1.5	0.4	1.9	0.5	1.0	0.8	2.4	0.6	1.5	0.5	1.4	0.8	0.3
Loud music exposure frequency	0.8	0.9	3.1	-0.0	0.7	1.4	0.9	0.9	1.3	0.9	-0.3	-0.3	-0.1	1.8	1.1	-0.6
Blood clot in the leg (DVT)	0.8	1.0	2.6	-1.4	-1.6	-0.9	-0.7	-1.2	-1.4	0.9	0.5	-0.6	-0.3	-0.0	-0.4	-1.3
Medication: Paracetamol	0.8	1.3	3.9	1.5	1.3	1.0	2.0	1.1	1.4	0.6	0.4	0.5	0.5	1.1	1.8	-0.2
Glaucoma (self-reported)	0.8	1.0	5.1	-1.3	-0.9	1.1	-0.3	0.4	-0.3	-0.7	-0.3	-1.7	0.0	-0.3	0.2	-2.3
High blood pressure (siblings)	0.8	1.2	2.9	0.9	1.2	0.3	1.5	1.0	1.2	1.3	1.1	0.7	1.4	0.4	1.7	0.3
Medication: Seretide 50 evohaler	0.8	1.0	2.9	-0.8	-1.5	-0.1	-1.0	-0.5	-1.4	-0.6	-0.5	-1.7	-0.8	-0.8	-1.0	-0.6
Heart disease (mother)	0.8	1.0	3.0	0.3	0.4	1.4	1.0	0.8	0.7	1.4	1.7	0.6	0.4	1.2	0.9	-0.5
Ever taken oral contraceptive pill	0.8	0.9	4.4	-1.0	-0.2	0.6	0.3	0.4	0.0	-0.4	1.9	1.1	0.8	-0.1	0.0	2.1
Mean Putamen Volume	0.7	0.8	1.9	-0.6	0.0	-0.8	-1.2	-1.0	-1.4	-1.0	-0.7	-0.7	-1.3	-0.8	-1.1	0.0
Neuroticism (2016)	0.7	1.1	3.8	1.9	0.6	0.3	0.8	0.7	0.5	1.9	1.0	1.2	1.1	-0.1	0.9	0.4
Allergy or Eczema	0.7	2.0	10.7	3.3	0.8	1.0	0.9	0.8	0.9	-0.9	0.5	0.8	1.4	1.4	0.9	2.1
Frequency of depressed mood in last 2 weeks	0.7	0.9	2.6	-0.4	-0.9	-0.3	-0.9	-1.0	-1.2	-0.6	0.0	-1.6	-1.4	-0.7	-1.0	-1.3
Ever used hormone-replacement therapy (HRT)	0.7	0.8	6.2	0.3	0.1	0.8	0.7	1.4	-0.1	0.6	2.5	-0.1	0.5	-0.2	0.8	0.5
Diabetes (mother)	0.7	0.9	4.0	0.9	0.6	2.0	0.1	1.6	0.9	-0.8	-0.8	0.8	0.4	1.0	-0.5	0.1
Relative age voice broke	0.7	1.1	2.2	-1.0	-1.4	-1.1	-1.2	-1.1	-1.5	-1.1	0.7	-0.1	-0.1	-1.4	-1.0	-0.6
Multivitamins +/- minerals	0.7	0.9	3.5	1.9	0.8	1.1	0.2	0.3	0.5	0.9	-0.3	0.7	0.3	1.4	0.3	1.2
Stomach or abdominal pain in last month	0.7	0.8	3.0	1.7	0.1	0.7	0.5	0.8	0.6	-0.5	0.9	-1.2	0.5	1.2	1.0	-1.0
Trunk fat mass	0.7	2.8	5.1	1.2	2.1	2.2	1.8	1.4	1.8	0.4	0.9	1.7	2.1	1.5	1.6	2.1
Falls in the last year	0.7	1.0	2.5	-1.3	-0.2	-1.6	-1.2	-1.1	-0.7	-1.1	-0.7	-0.8	-0.7	-0.6	-1.2	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.8	1.9	-1.3	1.4	-0.2	0.9	-0.1	1.1	1.4	-0.9	0.9	0.3	0.7	0.9	0.5
Medication: Lansoprazole	0.7	0.8	2.7	0.7	-0.7	0.8	0.1	0.3	-0.0	-1.0	-0.7	-1.6	-0.9	1.2	1.1	-0.6
Tense / ‘highly strung’	0.7	1.1	3.3	-1.0	-1.4	-0.8	-1.0	-0.9	-1.3	-0.1	-0.6	-0.6	-1.2	-1.2	-0.9	-1.8
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	2.2	0.6	0.8	0.7	1.5	1.4	0.7	1.4	1.0	0.9	1.5	0.6	1.2	-1.3
Long-standing illness, disability or infirmity	0.7	1.1	2.6	-0.8	-0.5	-0.6	-0.9	-1.0	-1.1	-1.6	-0.5	-1.4	-1.1	-1.0	-1.3	-1.3
Illnesses of father: None of the above (group 1)	0.7	0.8	3.8	1.1	-0.0	1.6	0.2	1.9	0.7	0.1	-0.3	0.9	0.7	1.1	0.3	0.0
Unable to work because of sickness or disability	0.7	0.9	3.2	1.3	-0.4	1.6	0.7	0.9	0.4	-0.1	1.2	-0.1	0.4	1.8	0.9	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.7	1.0	2.8	-1.2	-1.7	-1.0	-0.7	-1.2	-1.4	0.8	0.1	-0.7	-0.5	-0.0	-0.4	-1.3
Lupus	0.6	0.9	5.8	0.4	-0.1	0.2	-0.5	-0.4	-0.4	-0.5	2.4	0.5	1.1	0.3	-0.2	1.6
Number of incorrect matches in round	0.6	1.0	2.9	-0.2	0.6	1.3	0.8	0.8	0.7	1.4	1.7	0.6	1.4	0.7	0.6	0.8
Hip circumference	0.6	2.4	7.1	2.0	1.3	1.2	1.5	0.8	1.2	-0.5	1.0	2.0	1.8	1.4	1.3	2.7
Alcohol intake versus 10 years previously	0.6	0.9	3.5	1.4	-0.7	1.2	0.4	0.7	-0.4	-0.0	0.7	0.2	0.7	1.9	1.0	1.4
Body fat percentage	0.6	2.2	4.1	1.3	1.9	2.0	1.6	1.3	1.6	0.2	0.9	1.2	1.8	1.4	1.4	1.8
Number of children fathered	0.6	0.7	2.1	-1.0	-1.4	0.0	-0.7	0.1	-1.2	-1.3	-0.1	0.6	0.2	-0.9	-0.9	-0.0
Mouth/teeth dental problems: Loose teeth	0.6	0.7	5.1	-0.4	-0.1	-0.9	-0.2	-0.9	-0.1	0.0	-0.3	0.4	-0.4	-1.0	-0.8	-2.3
Smoking status: Previous	0.6	0.9	3.6	0.8	0.8	0.6	0.7	0.5	0.7	1.4	0.8	1.9	0.9	0.3	1.0	0.9
Osteoarthritis (self-reported)	0.6	0.8	3.0	0.9	-0.2	1.7	0.4	1.6	0.0	-0.6	0.2	-0.4	1.0	0.7	0.2	-1.3
Medication: Aspirin	0.6	0.8	2.4	0.5	1.1	0.6	0.9	0.5	0.9	0.7	0.8	0.6	1.0	0.2	1.1	1.6
Average weekly champagne plus white wine intake	0.6	0.9	2.5	-0.0	-1.2	1.1	-0.7	1.4	-0.6	-1.6	-1.0	-0.2	-0.7	-0.4	-1.2	-0.5
Leg fat percentage (left)	0.6	2.3	6.1	1.8	1.6	2.5	1.3	1.3	1.6	-0.2	0.0	1.0	1.5	1.9	1.5	1.8
Intelligence (Savage-Jansen 2018)	0.5	1.5	6.0	-2.4	-0.4	-0.9	-0.9	-0.6	-1.0	-1.0	-1.5	-1.8	-0.2	-1.4	-0.7	-0.9
Hair Pigment	0.5	13.5	26.3	-3.7	-4.9	-2.9	-4.5	-3.1	-5.1	-4.7	-1.6	-3.7	-3.1	-3.0	-4.0	-1.1
Hearing difficulty/problems: Yes	0.5	0.7	2.2	-1.5	-0.6	-1.5	-0.5	-0.0	-0.7	-0.0	0.3	0.4	-0.3	-1.0	-1.0	-1.4
Diabetes (father)	0.5	0.6	1.8	0.3	1.0	0.4	1.4	0.1	1.0	1.0	0.8	0.4	1.1	0.2	1.1	-0.1
Average weekly fortified wine intake	0.5	0.5	2.2	1.4	0.7	0.5	-0.0	0.7	0.7	-0.1	-1.5	0.6	-0.3	0.3	-0.0	0.8
High blood pressure (mother)	0.5	0.7	2.0	-1.4	-1.1	-1.0	-0.8	0.0	-0.9	-1.0	-1.1	-0.9	0.1	-0.7	-0.8	0.2
Past tobacco smoking	0.5	0.9	3.7	-0.3	-0.9	-0.6	-0.6	-0.5	-0.8	-1.3	-0.9	-1.9	-1.0	-0.1	-0.8	-1.4
Forced vital capacity (FVC)	0.5	1.8	4.0	1.4	1.3	1.5	0.9	0.9	1.5	1.5	-0.0	1.3	0.6	2.0	1.2	1.9
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.1	0.9	-0.3	-1.2	-0.1	-0.6	-0.5	0.2	1.1	0.5	1.4	-0.7	-0.2	1.0
Depression (self-reported)	0.5	0.6	2.8	0.2	-0.6	0.7	-0.2	-0.6	-0.5	0.5	-1.4	-0.3	-1.7	0.1	-0.3	1.2
Illnesses of mother	0.5	0.6	3.8	-0.3	0.2	-0.6	-0.2	-0.7	-0.2	0.5	-1.2	-0.3	-2.0	-0.5	-0.4	-1.2
Medication: Amlodipine	0.5	0.8	2.2	-0.0	0.9	-0.4	1.3	0.2	0.7	0.6	1.5	0.6	1.1	0.2	1.3	0.8
Birth weight	0.5	1.2	3.0	-1.5	-0.2	-0.4	-0.9	-0.6	-0.6	0.9	-1.7	-0.7	-1.5	-1.2	-0.6	-1.7
Comparative body size at age 10	0.5	1.3	3.3	0.1	-1.1	-1.2	-1.6	-1.0	-1.2	-1.2	-1.2	-0.5	-0.9	-0.8	-1.8	-1.2
Health satisfaction	0.5	0.7	2.0	-0.2	1.4	1.0	0.6	1.1	1.1	0.0	0.8	0.1	0.6	1.4	0.2	0.4
Emphysema/chronic bronchitis	0.5	0.5	2.0	-0.6	-1.4	-0.5	-0.5	-0.2	-1.3	-0.7	0.8	-0.7	-0.0	-0.6	0.3	0.6
Medication for pain relief, constipation, heartburn	0.5	0.8	3.1	-0.1	-1.3	-0.7	-1.5	-0.7	-1.2	-0.4	0.4	0.1	0.0	-0.8	-1.8	-0.4
Neck or shoulder pain in last month	0.5	0.7	2.0	-0.8	-0.9	-0.7	-0.2	-1.2	-0.8	-0.4	1.4	-0.9	-0.8	-0.2	-0.0	-0.8
Migraine (self-reported)	0.5	0.6	2.3	-0.0	0.1	-0.3	-0.2	0.4	-0.1	1.2	-1.5	-0.8	-0.5	-0.9	0.3	-1.2
Number of full sisters	0.5	0.6	2.9	0.2	0.4	-0.2	-0.1	-1.0	0.0	-1.5	0.7	-0.2	0.1	-0.1	-0.7	1.7
Overall health rating	0.5	1.2	4.2	0.6	2.1	1.1	1.4	0.2	1.2	0.1	1.4	0.9	0.7	0.6	0.4	1.4
Supplements: Vitamin C	0.5	0.6	1.4	1.2	0.8	0.8	0.9	1.0	0.9	0.6	0.2	0.5	1.1	-0.3	0.6	0.3
Mother’s age at death	0.5	0.6	2.7	-0.8	0.2	-1.1	0.0	-1.0	0.1	0.5	-0.9	0.1	0.1	-1.0	0.1	-1.6
Eye problems/disorders: Glaucoma	0.5	0.6	3.7	-0.3	-0.5	1.1	-0.5	0.6	-0.0	-0.7	-0.5	-1.1	-0.4	-0.1	-0.2	-1.9
Age started oral contraceptive pill	0.5	0.6	2.7	1.2	-0.7	-0.4	-0.9	-0.4	-0.7	0.7	-0.1	-0.1	-0.7	-1.6	-0.6	-0.0
Reaction Time	0.4	0.8	2.8	0.0	1.3	-0.8	0.4	-1.2	0.8	1.0	1.7	0.4	0.7	-0.6	-0.0	1.2
HbA1C	0.4	0.5	2.4	-1.3	0.1	-0.1	-0.0	-0.5	0.6	0.2	-0.8	0.2	-1.6	-0.2	-0.5	0.0
Height	0.4	8.6	18.6	0.5	2.9	4.0	3.0	2.6	2.9	2.7	2.6	4.3	3.9	0.9	2.2	3.1
Hand grip strength (right)	0.4	1.2	4.3	1.1	0.4	0.9	0.6	0.6	0.9	0.8	-0.3	2.1	1.6	1.4	0.6	1.4
Hayfever, allergic rhinitis or eczema	0.4	0.9	5.7	2.4	0.8	0.3	0.7	0.2	0.8	-0.8	0.5	-0.0	0.8	1.4	0.5	0.9
Medication: Atenolol	0.4	0.5	1.8	0.5	0.7	0.2	1.0	0.6	0.8	1.0	-0.7	0.0	0.3	0.7	1.3	0.3
Chronic bronchitis/emphysema (father)	0.4	0.5	2.5	-0.2	0.7	0.4	0.5	-0.2	0.5	0.1	1.1	0.8	0.3	0.5	0.3	1.6
Impedance of leg (left)	0.4	2.1	5.0	0.3	2.2	1.5	1.6	1.4	1.6	1.8	1.4	0.7	1.3	-0.5	1.5	1.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.3	-0.7	-0.7	-1.0	-0.4	-1.1	-0.9	-0.7	-0.4	-0.9	-0.4	-0.2	-0.0	-0.1
Qualifications: None of the above	0.4	0.8	5.1	2.3	0.3	1.4	0.3	-0.2	0.7	0.3	-0.2	-0.1	-0.8	1.1	0.8	0.5
Happiness	0.4	0.5	1.5	-0.9	1.0	-0.3	0.2	-1.1	0.3	0.5	-0.2	-1.2	-1.1	0.2	0.2	0.4
Peak expiratory flow (PEF)	0.4	0.8	4.6	-0.2	0.3	-1.3	-0.3	-1.4	-0.0	0.3	-2.1	0.3	-0.6	-0.4	0.5	1.2
Headache pain in last month	0.4	0.6	2.4	1.0	-0.1	0.9	0.6	0.1	0.0	1.2	0.3	-0.8	-0.6	0.4	1.0	-1.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.0	0.6	-0.4	-0.8	-0.8	0.2	-0.7	-0.3	-1.4	0.8	-0.0	-1.2	-0.4	0.1
Whole body fat mass	0.4	1.7	3.2	0.9	1.6	1.8	1.4	0.9	1.4	0.1	0.6	1.3	1.6	1.4	1.2	1.5
Family relationship satisfaction	0.4	0.5	1.0	-1.0	-0.7	-0.8	-0.4	0.4	-0.8	-0.7	-0.5	-0.7	-0.7	-0.4	-0.7	-0.9
Leg pain on walking	0.4	0.5	3.5	0.2	-0.2	-0.2	-0.2	-0.5	-0.4	-0.7	-0.6	-1.9	-0.9	-0.4	0.1	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.1	-0.4	1.0	0.2	0.5	-0.1	0.9	0.5	-1.5	0.1	-0.5	0.9	0.3	-0.6
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.8	1.0	-0.0	1.0	0.1	1.0	0.4	0.2	-0.3	1.3	0.4	0.8	-0.2	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.3	0.8	0.2	0.8	-0.2	0.0	0.2	-1.0	-1.1	-0.9	-1.0	0.9	0.4	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	1.8	-0.6	0.8	0.9	1.0	1.1	0.9	0.4	-0.0	0.9	1.2	0.9	1.3	1.2
Loneliness, isolation	0.4	0.5	1.9	0.3	-0.6	-0.0	-0.6	0.3	-0.7	-1.1	-0.9	-1.4	-0.8	-0.7	-0.1	-0.5
Medication: Gliclazide	0.4	0.4	2.9	0.9	0.0	-0.1	0.0	-1.3	-0.0	-0.0	-0.1	0.2	0.4	0.0	0.3	1.7
Ever smoked	0.4	0.6	3.1	0.1	1.0	-0.1	0.3	0.4	0.5	1.0	0.8	1.8	1.1	-0.3	0.1	1.0
Basal cell carcinoma (self-reported)	0.4	0.4	1.7	0.0	-0.2	-0.7	0.5	-0.5	0.0	1.1	0.9	1.3	0.7	0.2	0.5	0.2
Pack years of smoking	0.4	0.6	1.4	-0.6	-0.9	-1.1	-0.6	-0.9	-0.8	-0.8	0.9	0.1	-0.1	0.2	-1.2	0.5
Impedance of whole body	0.4	1.9	4.4	0.4	1.9	0.7	1.3	1.2	1.1	2.1	2.0	0.7	1.5	-0.8	1.0	1.8
Leg fat mass (left)	0.4	1.4	3.9	1.0	1.2	2.0	1.0	0.9	1.1	-0.5	0.1	1.0	1.3	1.5	1.0	1.5
Depressed Affect (Nagel 2018)	0.3	0.5	2.4	-0.4	-0.1	-0.7	-0.4	-0.6	-0.5	-1.0	-0.2	-0.8	-0.8	-1.5	-1.0	0.1
Age at First Birth	0.3	0.5	2.4	-0.8	-0.7	-0.1	-0.6	-0.4	-0.7	1.2	1.6	-0.1	0.0	-0.2	0.1	0.0
Respiratory disease	0.3	0.8	4.1	1.0	0.4	0.0	-0.1	0.5	-0.4	-0.7	1.3	0.5	1.0	-0.0	-0.6	2.0
Lung FVC	0.3	1.4	7.7	2.8	0.2	1.0	0.5	0.4	0.9	-0.2	-1.2	0.2	0.1	2.2	1.4	-0.1
Tanning	0.3	3.9	9.2	2.9	3.0	-0.3	2.6	0.6	3.0	1.1	0.1	1.8	1.5	2.2	2.5	0.1
Ever had hysterectomy (womb removed)	0.3	0.3	1.0	0.9	-0.0	0.4	0.3	0.6	0.4	0.6	0.4	0.2	1.0	0.5	0.6	-0.8
Pack years adult smoking proportion	0.3	0.5	1.2	-0.5	-0.7	-1.1	-0.5	-1.0	-0.7	-0.9	0.6	-0.0	-0.2	0.1	-1.1	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	3.2	0.1	0.4	1.0	-0.3	-0.3	-0.2	0.2	-0.2	-0.1	-0.8	-0.0	-0.5	1.8
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.1	0.5	0.2	1.1	0.1	0.8	0.1	0.3	0.0	-0.7	-0.8	0.2	-0.2	-0.7
Qualifications: CSEs or equivalent	0.3	0.4	1.8	-0.2	0.3	-0.8	0.2	-0.6	0.1	-0.3	-0.1	1.2	-0.3	-0.1	-0.5	1.3
Weight	0.3	1.7	3.5	0.8	1.3	1.7	1.3	0.8	1.3	-0.2	0.3	1.6	1.6	1.6	1.1	1.9
Asthma	0.3	0.6	2.4	0.1	0.4	-0.8	0.0	-0.5	-0.4	-0.9	1.6	-0.4	0.6	-0.1	-0.4	1.6
Medication: Cholesterol lowering	0.3	0.5	1.3	0.1	1.0	0.7	0.7	0.4	0.9	0.9	1.1	0.7	0.8	-0.4	0.2	0.4
Standing height	0.3	3.5	8.8	-0.3	1.9	1.9	2.0	1.7	1.6	2.0	1.2	2.6	2.2	0.5	1.6	3.0
Pulse wave reflection index	0.3	0.4	0.9	0.9	-0.8	0.5	-0.8	0.1	-0.7	-0.8	-0.2	-0.1	-0.1	-0.1	-0.5	0.7
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.9	0.1	0.1	0.5	0.6	0.6	0.4	0.3	1.1	-0.3	0.7	1.4	0.4	-0.3
Leg fat percentage (right)	0.3	1.1	4.3	1.2	1.0	2.1	0.8	1.1	1.0	-0.6	-0.2	0.6	0.9	1.1	0.9	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.0	0.0	-0.9	0.1	-0.8	-0.7	-0.5	-0.4	-0.9	0.2	-1.0	0.6	-1.0	-0.4
Wheeze or whistling in the chest in last year	0.3	0.4	2.8	-0.5	0.2	0.2	0.5	-0.1	-0.1	-0.5	1.7	-0.7	0.4	1.0	0.3	0.7
Age at first live birth	0.3	0.6	2.8	-1.2	-0.3	-0.6	-0.6	-0.4	-0.2	0.3	0.2	-0.4	-0.9	-0.7	-1.1	-1.7
Qualifications: College or University degree	0.3	1.0	6.5	-1.3	-0.6	-1.1	-0.6	0.1	-0.7	-0.5	0.5	-0.8	1.0	-0.8	-0.3	-2.5
Mean time to correctly identify matches	0.3	0.6	3.1	0.5	1.0	-0.7	0.4	-0.6	0.6	0.3	1.8	0.4	0.8	-0.8	-0.2	0.9
Leg fat mass (right)	0.3	1.0	3.1	0.9	1.0	1.8	0.8	0.8	0.9	-0.6	0.0	0.9	1.0	1.2	0.8	1.4
Average weekly red wine intake	0.3	0.4	1.5	0.5	1.2	-0.0	0.5	0.2	0.9	0.3	0.0	1.1	0.8	-0.4	0.3	0.5
Mood swings	0.3	0.5	2.2	1.0	1.5	-0.1	0.8	-0.3	0.7	0.0	0.7	0.5	0.1	-1.1	0.1	0.8
Diabetes diagnosed by doctor	0.3	0.5	1.2	-0.7	-0.8	-0.6	-0.6	-0.6	-1.1	-0.6	-0.1	0.4	0.4	-0.9	-0.4	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.3	-0.7	0.2	-0.0	0.5	-1.0	0.1	0.8	0.4	1.1	-0.1	-0.3	-0.1	-0.3
Back pain experienced in last month	0.3	0.4	2.0	-0.1	1.4	0.6	0.5	0.6	1.1	0.4	-0.0	-0.1	-0.3	0.7	0.4	-0.3
Asthma (self-reported)	0.3	0.5	2.6	0.3	0.6	-0.5	0.1	-0.5	-0.2	-0.7	1.4	-0.2	0.5	0.1	-0.4	1.6
Guilty feelings	0.3	0.4	1.8	-0.2	0.2	0.5	1.0	0.8	0.3	0.3	1.3	0.4	0.6	-0.0	0.8	-0.4
Wears glasses or contact lenses	0.3	0.3	1.7	-0.4	0.4	0.8	0.4	1.3	0.3	1.0	-0.1	0.3	-0.0	-0.3	0.1	-0.0
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.6	1.3	0.2	-0.0	0.5	-0.3	0.4	0.1	0.6	-0.0	-0.2	1.1	0.9	0.5
Medication: Lisinopril	0.3	0.4	2.6	0.4	0.1	0.3	0.6	0.0	-0.1	0.5	1.6	0.6	0.9	-0.2	0.8	0.5
Medication: Atorvastatin	0.3	0.4	1.2	-0.9	-0.9	0.1	-0.9	-0.2	-1.1	-0.4	0.1	-0.2	-0.4	-0.5	-0.6	0.3
Average weekly beer plus cider intake	0.3	0.4	1.8	-0.3	0.6	-0.9	0.2	-0.6	0.2	-1.3	-0.9	-0.7	-0.6	-0.7	-0.2	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.8	-0.2	-0.7	-0.3	-0.7	-0.2	-0.6	-1.3	-0.3	-0.9	-0.7	-0.2	-0.5	-0.6
Supplements: Calcium	0.3	0.3	1.3	-0.1	-0.0	-0.2	0.7	-0.3	0.1	0.8	1.1	-0.3	0.2	0.4	0.8	-0.7
Depression (Nagel 2018)	0.2	0.3	0.7	-0.2	-0.3	0.4	-0.4	-0.5	-0.8	0.1	-0.1	-0.6	-0.9	-0.7	-0.4	0.5
Worry (Nagel 2018)	0.2	0.4	1.3	0.2	-0.8	-0.5	-0.2	-0.0	-0.7	-0.5	0.1	-1.1	-1.0	-0.6	-0.3	-1.1
Alzheimer’s Disease (including proxy)	0.2	0.3	1.7	-1.3	-0.3	-0.5	-0.7	-0.1	-0.4	-0.5	0.3	-0.6	0.2	0.1	-0.5	-0.9
Ulcerative Colitis (UC)	0.2	0.4	1.3	1.1	-0.2	1.0	-0.6	-0.3	-0.2	0.6	-0.6	0.2	-0.8	0.2	-0.2	-0.7
Verbal and Numeric Reasoning (VNR)	0.2	0.5	2.6	-1.6	0.6	-0.0	0.4	0.8	0.1	-0.0	0.1	0.4	0.7	-0.6	-0.1	-1.3
HDL Cholesterol	0.2	0.4	2.7	0.0	0.0	-1.6	0.0	-1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Smoking Status	0.2	0.5	1.5	0.5	0.9	0.6	0.1	0.6	0.7	1.0	-0.1	0.6	0.9	0.4	0.7	1.2
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.9	-0.3	-0.7	-0.4	-0.5	-1.4	-0.8	-0.3	-0.4	0.2	0.2	-0.3	-0.0	1.3
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.9	-0.5	0.5	-0.3	-0.4	-0.5	0.0	0.2	-1.0	0.2	-0.3	-0.8	0.1	0.4
Angina	0.2	0.2	1.0	0.1	0.7	0.2	0.2	0.4	0.5	0.4	0.8	1.0	0.0	0.3	0.2	0.5
Medication: Metformin	0.2	0.2	1.3	0.1	-0.3	-0.0	-0.3	-0.4	-0.5	-0.5	0.4	0.3	0.7	-0.0	-0.1	1.2
Townsend deprivation index at recruitment	0.2	0.2	0.8	-0.3	-0.7	0.1	-0.6	-0.3	-0.8	-0.9	-0.3	-0.5	0.3	0.2	0.0	0.5
Current tobacco smoking	0.2	0.3	0.7	0.3	-0.5	-0.6	-0.8	-0.5	-0.7	-0.7	-0.9	-0.6	0.2	-0.4	-0.4	0.6
High blood pressure	0.2	0.6	1.6	-0.5	-0.2	-1.3	0.1	-0.8	-0.6	-1.2	0.6	-0.6	0.9	-1.3	0.2	-0.2
Supplements: Glucosamine	0.2	0.2	1.2	-0.3	-0.3	-0.7	0.1	-0.6	-0.2	0.0	0.2	-0.6	-0.4	-0.0	0.1	-1.1
Alcohol usually taken with meals	0.2	0.3	1.6	-0.1	-0.2	0.6	-0.3	0.9	-0.2	0.6	-0.5	0.4	-0.2	-0.2	-0.6	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	1.3	-1.1	0.3	-0.3	0.1	-0.4	0.1	-0.0	-0.5	-1.1	-0.9	0.2	-0.3	-0.9
Hearing difficulty/problems with background noise	0.2	0.3	1.2	0.7	0.4	0.1	0.5	0.7	0.6	-0.4	0.4	-0.8	-0.4	0.3	0.2	-1.1
Financial difficulties in last 2 years	0.2	0.2	1.6	-0.1	-0.2	0.4	0.2	0.3	-0.1	-1.3	0.7	-0.6	-0.3	0.2	-0.3	-0.3
Allergy	0.2	0.4	1.6	-1.3	-0.5	0.4	-0.3	0.2	0.1	0.4	-1.1	0.3	-0.5	-0.6	-0.1	-0.8
Medication: Simvastatin	0.2	0.3	1.0	-0.4	1.0	0.5	0.6	0.3	0.8	0.3	0.8	-0.2	0.2	-0.1	0.4	-0.7
Fluid intelligence score	0.2	0.4	1.7	-1.2	0.6	0.0	-0.0	0.3	0.2	-0.3	0.3	0.1	0.7	0.0	-0.4	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	2.1	0.1	-0.5	0.7	0.0	0.3	-0.3	-1.1	0.7	-1.5	-0.3	0.4	0.1	-0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	3.0	-0.3	-0.6	-0.6	-0.9	-0.8	-0.3	-0.1	-1.7	-0.7	-1.2	0.0	-0.5	-0.4
Prospective memory result	0.2	0.3	1.4	-0.5	0.0	-0.7	0.4	-0.6	0.0	0.5	1.2	-0.4	-0.3	0.0	0.1	0.7
Impedance of arm (left)	0.2	1.1	3.6	0.3	1.2	-0.2	0.7	0.8	0.4	1.9	1.8	0.6	1.1	-0.9	0.4	1.4
Exposure to tobacco smoke at home	0.2	0.2	0.7	-0.4	0.6	0.2	0.1	0.2	0.4	0.0	-0.8	-0.6	0.2	0.5	0.4	0.6
Arm fat-free mass (right)	0.2	0.9	2.8	-0.0	0.9	1.7	0.8	0.7	1.1	-0.5	-1.0	1.0	0.4	1.4	0.7	1.2
Angina (self-reported)	0.2	0.3	0.8	0.2	0.9	0.3	0.3	0.4	0.7	0.4	0.5	0.9	-0.0	0.4	0.4	0.4
Arm predicted mass (right)	0.2	1.1	3.2	0.1	0.9	1.8	0.9	0.7	1.1	-0.3	-0.9	1.2	0.5	1.5	0.9	1.4
Had major operations	0.2	0.2	0.7	-0.6	-0.1	-0.3	-0.4	-0.2	0.1	-0.3	-0.8	-0.4	-0.4	0.5	-0.1	-0.8
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.9	-0.8	0.4	-0.6	0.1	-0.9	0.3	1.0	0.5	0.2	-0.1	0.7	0.4	0.1
Hypertension (Self-reported)	0.2	0.6	2.1	-0.7	-0.3	-1.4	-0.1	-0.9	-0.7	-1.1	0.7	-0.5	0.7	-1.3	-0.1	-0.4
Illnesses of father: Heart disease	0.2	0.3	1.1	-0.6	-0.4	-1.0	0.1	-0.5	-0.4	-0.1	-0.7	-0.9	-0.7	-0.2	0.3	0.0
Leg fat-free mass (right)	0.2	0.8	3.2	0.0	0.9	0.9	1.0	0.4	0.9	-0.0	-0.0	1.1	1.1	1.8	0.9	1.0
Arm fat percentage (left)	0.2	0.6	1.3	0.9	0.8	1.0	0.6	0.5	0.6	-0.5	0.2	0.4	1.0	1.1	0.6	1.1
Qualifications: nursing, teaching	0.2	0.4	2.4	-1.0	-0.5	-0.7	-0.2	-0.1	-0.2	0.0	-0.6	-0.6	0.3	0.4	0.3	-1.5
Commuting to job workplace: Walk	0.2	0.3	0.9	0.2	0.1	-0.7	0.6	-0.1	0.1	-0.3	0.4	0.0	1.0	-0.1	1.0	0.6
Medication for cholesterol	0.2	0.4	1.7	0.6	0.2	0.9	0.1	-0.0	0.7	0.4	-1.3	0.8	0.1	0.7	-0.1	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.7	0.4	-0.5	0.9	-0.5	-0.1	-0.4	0.4	-0.3	-0.6	0.1	0.4	0.2	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	1.3	0.4	-0.3	-0.1	-0.4	0.1	-0.0	0.3	-1.1	-0.7	-1.1	0.2	-0.1	-0.9
Leg predicted mass (right)	0.2	0.8	3.3	0.0	0.9	0.9	1.0	0.4	0.9	-0.0	-0.1	1.1	1.1	1.8	0.9	1.0
Miserableness	0.2	0.4	2.3	0.2	0.6	-0.2	0.4	-0.4	0.1	0.1	1.0	0.3	0.5	-0.6	0.2	1.5
Hearing aid user	0.2	0.3	0.8	0.2	0.8	-0.7	0.4	-0.4	0.6	-0.2	-0.2	-0.1	-0.6	-0.4	-0.4	-0.9
Medication: Blood pressure	0.2	0.5	2.4	-0.1	0.0	-1.2	0.6	0.2	-0.2	-0.4	1.5	-0.6	0.6	-0.0	0.6	0.5
Irritability	0.2	0.3	0.8	-0.3	0.9	0.7	0.9	0.1	0.4	0.3	0.4	-0.5	-0.1	0.2	0.6	-0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.5	-0.2	0.6	0.5	-0.0	0.4	0.3	-0.4	-0.5	0.7	0.7	-0.7	-0.6	0.2
Diastolic blood pressure, automated reading	0.2	0.6	2.1	-0.3	1.4	0.5	0.8	0.0	1.2	0.9	-1.0	0.3	-0.1	1.0	0.6	-0.2
Pain experienced in last month	0.2	0.4	1.3	-0.3	0.2	-0.1	-0.0	0.0	0.1	0.7	-0.4	1.1	1.0	-0.7	-0.2	1.1
Bipolar Disorder or Schizophrenia	0.1	0.3	2.0	0.0	0.0	1.3	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Neuroticism (Nagel 2018)	0.1	0.3	0.9	0.7	0.5	0.5	0.9	0.8	0.5	-0.0	1.0	-0.3	0.1	-0.3	0.6	-0.0
Schizophrenia (2018)	0.1	0.3	2.0	0.0	0.0	-1.4	0.0	-1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.1	0.1	0.4	-0.4	-0.4	-0.1	0.1	-0.6	0.0	-0.3	0.6	-0.1	-0.2	0.6	-0.0	0.0
Rheumatoid Arthritis	0.1	0.1	0.6	0.0	0.0	0.7	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.1	0.1	1.1	0.0	0.0	-1.0	0.0	-0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Systolic Blood Pressure	0.1	0.6	1.8	-1.1	0.7	-1.3	0.3	-0.8	-0.1	0.2	0.6	0.4	-0.2	-1.1	-0.4	1.3
Cardiovascular Disease	0.1	0.3	1.4	0.4	1.2	-0.8	0.6	-0.3	0.6	-0.1	0.7	0.0	0.7	-0.4	0.5	0.4
Neuroticism	0.1	0.3	1.5	-0.4	-0.1	-0.3	0.2	-0.5	-0.5	-0.2	0.4	-0.8	-0.4	-1.2	0.0	-0.1
Chronotype (morning person)	0.1	0.3	1.6	-0.2	-0.1	-0.1	0.1	-0.2	-0.5	0.2	1.2	-0.6	-0.4	-0.7	-0.6	0.2
Hand grip strength (left)	0.1	0.2	0.7	0.5	-0.6	0.1	-0.5	-0.1	-0.2	0.3	-0.8	0.8	0.6	0.6	-0.3	-0.0
Number of treatments/medications taken	0.1	0.2	1.8	-0.0	0.0	0.1	-0.0	-0.1	-0.3	-0.2	1.3	0.1	0.3	-0.4	0.1	0.6
Systolic blood pressure, automated reading	0.1	0.4	2.2	-1.5	-0.1	-0.5	-0.3	-0.5	-0.4	-0.3	-0.6	-0.0	-0.8	-0.5	-0.7	-0.6
Severe depression (siblings)	0.1	0.2	1.0	0.1	-0.1	-0.5	-0.3	-0.5	-0.0	0.2	1.0	-0.3	-0.3	0.4	-0.0	-0.1
Impedance of leg (right)	0.1	0.7	2.8	-0.4	1.1	0.7	0.6	0.9	0.6	1.0	0.8	0.1	0.2	-1.7	0.3	1.0
Leg fat-free mass (left)	0.1	0.3	1.1	-0.2	0.4	0.6	0.4	0.2	0.3	-0.6	-0.6	0.8	0.4	1.0	0.2	0.9
Fed-up feelings	0.1	0.2	0.6	0.4	0.2	0.2	0.0	-0.6	0.0	0.8	0.7	0.1	-0.0	-0.2	0.2	0.7
Serious illness, injury or assault to yourself	0.1	0.2	0.9	0.3	0.2	-0.5	-0.3	-0.2	-0.0	-0.2	-0.2	0.9	-0.0	-0.4	-0.7	0.3
Sitting height	0.1	0.6	2.0	-1.2	-1.4	0.2	-0.5	-0.9	-1.4	-0.5	-0.5	-0.5	-0.5	-0.5	-0.0	0.8
Body mass index (BMI)	0.1	0.5	1.8	1.0	0.5	0.9	0.3	0.1	0.6	-1.2	-0.5	0.4	0.6	1.4	0.4	0.5
Leg predicted mass (left)	0.1	0.4	1.2	-0.2	0.4	0.7	0.5	0.3	0.4	-0.5	-0.5	0.9	0.5	1.1	0.3	0.9
Had other major operations	0.1	0.2	0.4	-0.5	0.1	0.5	0.3	0.5	0.1	-0.6	0.6	-0.1	0.2	0.3	0.1	-0.4
Neuroticism score	0.1	0.2	0.7	-0.4	-0.0	-0.2	0.3	-0.4	-0.4	0.2	-0.0	-0.5	-0.6	-0.8	0.1	-0.8
Impedance of arm (right)	0.1	0.7	3.6	-0.3	0.5	-0.5	0.0	0.3	-0.4	1.4	1.9	0.0	0.7	-1.3	-0.2	0.8
Arm fat percentage (right)	0.1	0.2	0.6	0.6	0.4	0.7	0.1	0.2	0.2	-0.8	-0.0	0.2	0.7	0.8	0.2	0.7
Trunk fat-free mass	0.1	0.5	2.3	-0.7	-0.1	1.2	0.1	0.3	0.2	-0.7	-1.5	0.8	-0.0	0.8	0.2	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.1	0.8	-0.2	0.3	0.0	0.3	0.4	0.5	-1.1	-0.2	-0.3	1.4	0.7	-0.2
Arm fat mass (right)	0.1	0.5	1.1	0.6	0.7	0.9	0.5	0.3	0.5	-0.8	0.0	0.6	1.0	1.1	0.4	0.9
Trunk predicted mass	0.1	0.5	2.4	-0.7	-0.1	1.2	0.1	0.3	0.2	-0.7	-1.6	0.9	-0.0	0.8	0.1	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.5	0.4	-0.3	-0.2	-0.1	-0.5	-0.1	0.7	-0.0	0.3	-0.6	0.5	-0.4	-0.3
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.5	-0.6	-0.4	-0.5	-0.7	-0.0	-0.5	-0.2	-0.7	-0.4	-0.7	0.5	-0.2	0.1
Medication: Blood pressure	0.1	0.2	1.0	-0.1	-0.2	-0.3	-0.0	-1.0	-0.2	0.2	0.2	0.4	0.8	-0.9	-0.1	-0.1
Alcohol intake frequency.	0.1	0.1	0.6	0.3	-0.0	0.1	-0.2	-0.1	-0.4	0.1	0.1	0.3	0.8	0.2	-0.4	0.7
Age at last live birth	0.1	0.2	0.9	-0.0	0.3	-0.5	0.1	-0.3	0.3	0.5	0.5	0.9	0.2	0.5	-0.5	-0.5
Whole body fat-free mass	0.1	0.5	1.2	-0.4	0.3	1.1	0.4	0.4	0.4	-0.5	-1.1	1.0	0.3	1.1	0.4	0.9
Friendships satisfaction	0.1	0.2	0.6	-0.5	0.8	-0.7	0.1	-0.2	0.1	-0.3	0.5	-0.1	0.4	-0.2	-0.2	0.5
Smoking status: Current	0.1	0.2	0.7	0.5	-0.2	-0.1	-0.5	-0.0	-0.3	-0.5	-0.9	-0.5	0.0	-0.0	-0.2	0.7
Whole body water mass	0.1	0.5	1.2	-0.4	0.3	1.1	0.4	0.3	0.4	-0.6	-1.0	1.0	0.3	1.1	0.3	0.8
Arm fat mass (left)	0.1	0.5	1.2	0.5	0.8	0.9	0.5	0.3	0.6	-0.8	-0.0	0.7	0.8	1.0	0.4	1.1
High cholesterol (Self-reported)	0.1	0.3	1.3	-0.7	0.4	1.2	0.4	0.3	0.5	0.3	-0.3	0.1	0.0	0.2	0.5	0.4
Medication: Bendroflumethiazide	0.1	0.2	0.7	0.3	0.4	0.8	0.3	0.2	0.2	0.0	-0.1	0.2	0.8	0.1	0.5	0.6
Basal metabolic rate	0.1	0.7	1.5	-0.2	0.6	1.2	0.7	0.5	0.7	-0.6	-0.7	1.1	0.7	1.2	0.5	1.2
Arm fat-free mass (left)	0.1	0.7	2.4	-0.3	0.7	1.6	0.7	0.5	0.9	-0.5	-0.7	1.1	0.6	1.3	0.6	1.0
Vascular/heart problems diagnosed by doctor	0.1	0.4	1.1	0.1	-0.1	1.1	-0.5	0.4	0.2	0.8	-0.8	0.4	-0.9	0.9	-0.5	0.3
Cholesterol lowering medication	0.1	0.2	0.5	-0.4	0.5	0.3	0.2	0.1	0.1	-0.1	0.7	-0.7	0.0	0.0	0.7	0.0
Arm predicted mass (left)	0.1	0.7	2.0	-0.2	0.5	1.4	0.5	0.5	0.6	-0.8	-1.0	1.0	0.2	1.2	0.4	1.1
Bipolar Disorder (2018)	0.0	0.0	0.5	0.0	0.0	0.7	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.4	0.0	0.0	0.6	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.5	0.0	0.0	0.7	0.0	-0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	-0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
BMI	0.0	0.2	0.5	-0.3	0.7	0.1	0.0	-0.7	0.3	-0.6	-0.4	0.2	0.1	0.5	-0.2	0.4
Knee pain experienced in last month	0.0	0.1	0.3	0.3	0.1	0.0	0.3	0.1	0.1	-0.6	0.2	-0.0	0.1	0.5	-0.0	-0.1

Hub : Genes

IFITM3

Models

Trait associations