Best TWAS P=2.28e-10 · Best GWAS P=2.41e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Putamen basal ganglia | RRM1 | 0.20 | 0.11 | lasso | 4 | 0.10 | 2.2e-03 | 4.1 | 6.0 | 2.4e-09 | 0.96 | 0.03 | 0.88 | FALSE |
| 2 | GTEx | Lung | STIM1 | 0.19 | 0.20 | lasso | 5 | 0.19 | 3.5e-14 | 6.3 | 6.3 | 2.3e-10 | 1.00 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | STIM1 | 0.03 | 0.04 | blup | 142 | 0.03 | 8.8e-05 | 5.8 | -5.9 | 4.8e-09 | -0.93 | 0.03 | 0.97 | FALSE |