Hub : Genes

STIM1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1210 0.0320 2.3e-05 0.025 0.050 0.060 0.049 0.049 4.6e-04 9.0e-07 7.9e-08 1.3e-06 1.3e-06
2 GTEx Esophagus Muscularis 0.1200 0.0480 2.5e-03 0.008 NA 0.013 NA 0.001 1.0e-01 NA 4.8e-02 NA 2.7e-01
3 GTEx Heart Left Ventricle 0.1745 0.0582 3.8e-04 0.092 NA 0.072 NA 0.081 1.4e-05 NA 1.2e-04 NA 4.1e-05
4 GTEx Lung 0.1854 0.0474 2.6e-10 0.196 NA 0.183 NA 0.186 5.7e-15 NA 5.5e-14 NA 3.5e-14
5 GTEx Thyroid 0.3260 0.0560 7.3e-15 0.276 NA 0.268 NA 0.266 3.0e-21 NA 1.2e-20 NA 1.8e-20
6 ROSMAP Brain Pre-frontal Cortex 0.1219 0.0338 5.0e-06 0.052 0.055 0.058 0.055 0.053 2.4e-07 1.4e-07 5.9e-08 1.2e-07 1.8e-07
7 YFS Blood 0.0251 0.0085 1.1e-05 0.021 0.015 0.020 0.017 0.020 1.2e-07 7.7e-06 2.8e-07 1.7e-06 3.4e-07
8 TCGA Kidney Renal Clear Cell Carcinoma 0.0322 0.0150 2.2e-04 0.036 0.034 0.025 NA 0.023 6.3e-05 8.8e-05 6.6e-04 NA 1.0e-03
9 TCGA Thyroid Carcinoma 0.1480 0.0510 1.3e-10 0.086 0.111 0.110 NA 0.097 1.0e-08 6.9e-11 7.5e-11 NA 1.2e-09

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.1 0.2 0.6 0.2 0.6 -0.2 -0.8 0.1 0.0 -0.0 0.4 -0.6
Bipolar Disorder or Schizophrenia 0.2 0.5 1.7 0.9 0.6 0.4 0.0 -0.9 1.3 -0.6 0.2 -0.0
Depressed Affect (Nagel 2018) 0.4 0.9 2.9 -0.9 -1.1 -1.5 -0.0 -0.3 -1.7 -0.4 0.1 -0.8
Depression (Nagel 2018) 0.2 0.3 1.0 0.2 0.2 -0.9 -0.3 0.1 -0.5 -1.0 0.1 -0.6
Intelligence (Savage-Jansen 2018) 0.4 1.4 4.3 -1.4 -1.1 -0.4 -1.0 -0.6 -2.1 -1.0 0.8 -1.2
Neuroticism (Nagel 2018) 0.5 1.2 3.0 -1.2 -1.3 -1.2 -0.4 -0.2 -1.7 -0.8 0.6 -1.4
Schizophrenia (2018) 0.4 0.8 2.8 0.9 0.3 0.7 0.7 -1.2 1.7 -0.7 -0.1 0.4
Schizophrenia vs Biploar Disorder 0.8 1.0 3.5 1.4 -0.9 0.9 -0.1 -0.8 1.9 -1.2 0.4 -0.1
Worry (Nagel 2018) 0.5 1.1 3.1 -1.1 -1.0 -0.0 -0.9 -0.5 -0.9 -1.3 0.9 -1.8
Alzheimer’s Disease (in mother) 0.3 0.4 0.8 0.6 -0.6 0.8 0.5 -0.9 0.1 -0.9 -0.0 -0.4
Alzheimer’s Disease (in father) 0.7 0.8 1.8 -0.3 1.1 -1.0 1.3 0.8 0.4 0.9 -1.0 0.4
Alzheimer’s Disease (including proxy) 0.2 0.3 1.2 0.6 -0.0 0.4 0.8 -0.3 1.1 -0.2 -0.2 -0.2
Crohns Disease (2017) 0.4 0.9 3.8 -0.4 0.2 1.0 -1.9 -0.3 0.1 -0.2 1.6 -0.3
Irritable Bowel Disease (IBD) 0.7 1.6 5.0 -2.2 -1.5 0.6 -1.4 -0.2 -1.1 -0.7 1.3 -0.9
Ulcerative Colitis (UC) 0.6 1.1 4.0 -1.9 -2.0 -0.6 0.1 0.3 -0.9 -0.5 0.1 -0.9
Major Depression (MDD) 0.4 0.4 2.3 1.1 0.1 -0.2 -0.1 -1.5 0.4 -0.3 0.1 0.4
Reaction Time 0.1 0.2 0.6 0.4 0.4 -0.8 -0.5 -0.1 0.1 0.3 0.4 -0.3
Verbal and Numeric Reasoning (VNR) 0.2 0.6 1.7 -1.3 -0.6 -0.2 -0.7 -1.0 -1.2 -0.3 0.5 -0.2
Breast Cancer 0.9 2.1 3.9 1.4 1.9 2.0 -1.7 -0.5 1.4 -0.3 1.8 0.9
Ovarian Cancer 0.8 1.1 5.1 -2.3 0.3 0.1 -0.9 -0.6 -1.7 0.3 0.3 0.5
Prostate Cancer 1.1 1.6 2.6 1.5 1.6 -0.2 1.6 0.6 1.0 1.3 -1.4 1.2
Age at First Birth 0.5 0.8 2.8 -0.7 -0.4 -0.8 -1.3 -0.1 -1.7 -0.1 1.0 -0.4
Bipolar Disorder (2011) 0.8 0.8 2.3 -1.5 0.3 -0.7 1.0 0.6 -1.0 0.5 -0.8 1.0
Body Mass Index (BMI) (2010) 1.1 1.5 4.1 -0.3 2.0 1.8 0.9 1.1 -0.1 1.3 -0.4 1.5
Coronary Artery Disease (CAD) 0.7 0.9 2.6 0.1 -0.5 -1.5 -1.0 0.2 -1.6 -0.4 0.2 -1.3
Crohns Disease (2012) 0.4 0.7 3.2 0.2 -0.4 0.5 -1.8 -0.6 -0.0 -0.0 1.6 -0.0
Mean Putamen Volume 0.6 0.7 2.6 1.3 -0.6 -0.5 0.7 1.6 0.2 0.6 -0.4 0.6
Fasting Glucose 3.2 3.8 11.4 2.8 2.1 2.9 0.3 0.9 3.4 0.6 0.8 0.6
HbA1C 0.6 0.7 2.0 1.4 -1.1 -0.4 1.0 -0.2 0.9 -0.3 -0.7 -0.4
HDL Cholesterol 0.7 1.1 2.8 -1.0 -0.1 0.1 1.3 1.3 -1.5 0.7 -1.7 0.4
LDL Cholesterol 0.2 0.3 0.9 -0.4 0.3 -0.3 -0.9 -0.5 -0.8 -0.2 0.5 -0.9
Lupus 0.3 0.5 1.0 -0.5 -0.9 -1.0 0.4 0.7 -0.4 0.7 -0.9 0.3
Neuroticism (2016) 0.5 0.7 2.5 0.1 -1.6 -1.3 0.0 0.1 -0.3 -0.4 0.0 -1.2
Primary Biliary Cirrhosis 0.3 0.5 1.4 -1.2 0.2 -0.4 -0.1 0.8 -1.0 0.8 -0.2 -0.2
Rheumatoid Arthritis 2.6 3.6 13.0 -0.4 0.8 -3.6 2.3 2.1 -1.8 1.0 -2.1 0.8
Schizophrenia (2014) 0.3 0.7 1.5 1.2 0.4 0.4 1.2 -0.8 1.1 -0.2 -0.6 0.8
Triglycerides 0.8 1.2 5.1 1.4 0.1 0.3 -0.8 -1.5 2.2 -0.5 0.7 -0.6
Type 2 Diabetes (T2D) (2012) 0.8 0.9 1.6 1.1 -1.3 -1.1 -0.9 -1.0 0.2 -0.8 0.4 -1.3
Ulcerative Colitis 0.3 0.5 2.4 -1.5 -1.0 -0.1 0.1 -0.1 -0.6 -0.5 0.2 -0.4
Blood Eosinophil Count 0.3 2.1 9.4 -2.6 0.9 0.6 -0.3 1.0 -3.1 0.3 0.3 0.8
Blood Platelet Count 1.0 11.0 17.6 -3.4 -2.0 0.8 -4.0 -3.4 -2.9 -4.0 3.8 -4.2
Blood Red Count 0.3 2.5 6.6 -0.8 -0.5 -2.1 1.4 2.0 -1.4 2.6 -1.6 0.1
Blood White Count 0.2 1.1 6.5 -1.7 0.2 0.2 -0.2 0.3 -2.5 0.5 -0.1 0.8
Heel T-Score 0.4 3.0 12.1 3.5 0.0 2.2 -1.2 -0.7 2.6 0.2 1.1 -0.7
BMI 0.3 1.9 3.7 -1.0 0.4 1.1 1.5 1.4 -1.7 1.9 -0.9 1.9
Height 0.1 1.1 3.4 -1.3 -0.8 -1.3 -1.0 0.3 -1.8 -0.1 1.0 0.5
Waist Hip Ratio (WHR) 0.2 0.7 1.4 -1.1 0.4 1.2 -0.8 -0.6 0.4 -1.1 1.1 -0.2
Systolic Blood Pressure 0.4 2.1 9.5 0.6 3.1 0.4 0.9 0.8 0.6 1.3 -0.2 2.3
Smoking Status 0.4 0.8 2.4 -1.2 0.4 1.3 1.3 0.4 0.1 0.2 -0.3 1.6
Allergy or Eczema 0.2 0.6 3.3 -1.8 -0.5 0.2 0.1 0.5 -0.9 0.8 -0.2 0.6
Cardiovascular Disease 0.1 0.5 3.3 -0.5 0.0 1.8 -0.0 0.3 0.1 -0.3 0.6 0.0
Hypothyroidism (self reported) 0.7 1.6 3.6 -1.9 -0.7 -0.7 1.3 1.3 -1.5 1.0 -1.3 1.0
Respiratory disease 1.6 3.7 7.9 -1.2 -0.0 1.4 -2.8 -2.6 -1.4 -2.0 2.7 -1.3
Type 2 Diabetes (T2D) (2018) 0.9 1.7 4.9 1.0 0.1 -0.2 -1.9 -2.2 0.8 -1.2 1.5 -1.1
Lung FEV1/FVC ratio 3.0 15.2 40.2 0.2 1.1 -2.4 6.3 4.4 -0.6 4.5 -5.9 4.0
Lung FVC 0.9 4.6 11.8 -1.4 -1.2 2.5 -3.3 -1.2 0.1 -1.8 3.4 -2.0
Neuroticism 0.9 2.3 7.4 -0.7 -2.4 -0.4 -1.3 -1.0 -0.6 -1.5 1.1 -2.7
Chronotype (morning person) 0.7 1.6 4.5 -1.1 0.6 -1.1 2.1 0.1 -1.6 0.3 -1.8 0.9
Hair Pigment 0.1 2.0 8.0 2.8 0.6 0.9 0.5 -0.9 2.3 -1.3 0.2 -0.7
Tanning 0.2 2.2 9.3 0.8 0.6 3.0 -1.7 0.3 1.3 0.6 1.8 1.3
Hand grip strength (left) 0.2 0.5 1.7 -0.9 0.7 -0.9 0.1 -0.0 -1.3 0.6 0.2 0.5
Number of treatments/medications taken 0.4 0.8 1.9 -0.2 -0.5 0.3 -1.3 -0.7 -0.8 -1.4 0.9 -1.1
Average weekly spirits intake 1.5 1.9 9.9 -3.1 -1.0 0.5 -0.1 0.7 -2.1 0.7 -0.5 -0.1
Sensitivity / hurt feelings 1.1 2.0 6.8 -0.0 -1.0 -0.9 -0.9 -2.6 -0.0 -1.4 0.5 -2.4
Frequency of depressed mood in last 2 weeks 0.9 1.2 3.6 -0.3 0.7 -1.9 1.1 1.4 -0.6 0.9 -1.3 0.9
Hearing difficulty/problems: Yes 0.4 0.6 3.2 0.3 -1.8 1.0 0.2 0.4 0.7 0.0 -0.0 0.1
Relative age of first facial hair 0.3 0.6 2.1 -1.4 -0.5 0.4 1.1 0.8 -0.7 0.4 -0.6 0.7
Other serious medical condition/disability diagnosed by doctor 1.4 1.8 3.7 -1.9 1.1 0.5 0.8 1.1 -1.4 1.5 -1.5 1.7
Ever used hormone-replacement therapy (HRT) 1.2 1.6 3.4 -0.5 -1.4 -0.4 1.2 1.5 -1.8 1.0 -1.3 1.4
Ever had hysterectomy (womb removed) 1.1 1.3 4.2 1.2 -0.6 1.4 -2.0 -0.3 -0.3 -0.3 1.5 -0.9
Systolic blood pressure, automated reading 0.5 1.6 4.5 0.3 1.6 0.3 1.0 1.2 -0.2 1.9 -0.8 2.1
Eye problems/disorders: Diabetes related eye disease 1.6 1.7 3.6 -1.3 0.4 -1.0 -1.7 -1.8 0.2 -1.4 1.9 -0.7
Angina 0.9 1.1 2.8 -0.3 -0.5 1.0 -1.4 -1.1 -0.6 -1.7 1.3 -0.8
Medication for hormone replacement therapy 1.0 1.1 6.7 -0.5 -0.6 -2.6 0.3 0.8 -1.2 0.2 -0.3 -0.1
Vitamin and mineral supplements 0.7 1.0 4.1 -1.5 -0.8 -1.1 0.4 0.6 -2.0 -0.2 -0.1 -0.5
Supplements: Zinc 1.1 1.2 4.3 1.8 -0.7 1.2 -0.1 -0.5 2.1 -0.7 0.7 -0.5
Medication: Co-codamol 0.9 1.0 3.2 0.9 -0.9 1.4 -0.2 -1.0 0.8 -1.8 0.7 -0.7
Medication: Metformin 0.6 0.8 2.9 -0.8 -0.5 -0.6 -0.9 -1.7 -0.6 -0.8 0.9 -0.3
Diabetes (father) 0.4 0.5 2.7 0.6 -0.4 1.6 0.8 0.0 0.2 -0.2 -0.2 0.1
Diabetes (mother) 1.0 1.3 2.8 -0.1 -1.4 -0.8 -1.5 -0.9 -1.2 -0.6 1.4 -1.7
Severe depression (siblings) 1.4 1.5 3.6 0.1 0.4 0.6 -1.6 -1.0 0.4 -1.7 1.7 -1.9
Pack years adult smoking proportion 0.2 0.4 0.9 0.3 -0.1 -0.8 -1.0 -0.4 0.6 -0.6 0.9 -0.1
Impedance of leg (right) 0.5 2.4 11.5 0.2 -1.8 -3.4 1.4 0.7 -0.5 -0.0 -1.9 -0.3
Leg fat-free mass (left) 0.2 1.2 2.7 -1.3 1.2 1.6 -0.4 0.3 -1.2 0.9 0.8 1.3
Trunk fat percentage 0.3 1.0 2.0 -0.8 -0.4 0.2 1.3 1.4 -0.9 1.0 -1.0 1.4
Hand grip strength (right) 0.1 0.3 0.9 -0.3 0.1 -0.3 -0.8 -0.6 -0.0 -0.6 0.9 -0.2
Townsend deprivation index at recruitment 0.4 0.5 1.1 -0.4 0.0 0.5 -0.9 -0.9 0.3 -1.1 1.0 -0.5
Current tobacco smoking 1.1 1.9 5.5 0.6 1.8 0.6 0.9 1.6 0.7 1.5 -0.9 2.4
Average weekly fortified wine intake 0.9 1.0 3.0 0.9 -0.8 -0.1 -1.7 -1.6 0.8 -0.6 0.9 -0.8
Maternal smoking around birth 0.5 0.7 1.7 0.4 0.9 1.3 -0.8 0.7 0.8 0.9 -0.1 1.3
Fed-up feelings 0.3 0.5 1.2 -0.0 -0.5 -1.1 -0.7 -0.7 -0.8 -0.8 0.8 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 2.8 0.7 0.7 -1.3 1.2 1.7 0.1 0.8 -1.5 1.3
Relative age voice broke 0.2 0.3 1.2 -0.8 1.1 0.1 -0.3 -0.6 -0.5 0.1 0.5 0.1
Taking other prescription medications 0.3 0.4 1.2 -1.1 -1.1 0.2 -0.3 0.5 -0.7 0.6 -0.2 0.2
Age when periods started (menarche) 0.2 0.5 2.1 1.4 -0.2 -1.2 -0.0 0.5 0.4 -0.5 -0.1 -0.3
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 1.4 1.2 -0.6 0.4 -0.6 0.8 -0.7 0.6 0.3 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 1.8 4.2 10.8 3.3 -0.4 2.1 -2.0 -2.0 2.2 -1.6 1.9 -1.8
Tinnitus: Yes, but not now, but have in the past 0.7 0.7 1.8 -1.2 -0.8 -0.7 0.4 0.3 -1.1 -1.3 0.3 -0.9
Qualifications: CSEs or equivalent 0.3 0.5 1.7 0.3 0.4 -0.8 -0.7 0.2 -0.2 -1.0 0.2 -1.3
Serious illness, injury or assault to yourself 0.2 0.2 0.6 0.0 0.8 -0.3 0.3 -0.4 -0.4 -0.3 -0.4 0.6
High blood pressure 0.3 0.9 2.2 -0.9 0.8 0.6 0.8 1.5 -0.9 1.1 -0.3 1.2
Hayfever, allergic rhinitis or eczema 0.3 0.6 3.1 -1.8 -0.2 0.4 -0.0 0.3 -1.2 0.8 0.0 0.5
Multivitamins +/- minerals 1.0 1.2 4.1 1.9 0.5 1.0 -1.0 -0.7 2.0 -0.0 0.9 -0.4
Stomach or abdominal pain in last month 0.7 0.9 4.5 1.2 2.1 -0.9 -0.1 0.2 0.6 0.0 0.1 0.8
Supplements: Glucosamine 0.5 0.7 1.8 -0.7 -1.3 -1.3 -0.1 -0.7 -0.0 -0.9 -0.4 -0.8
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.2 0.5 0.7 -1.0 0.3 -1.1 0.1 -0.2 -0.4 0.3
Medication: Atenolol 0.6 0.8 3.1 -0.8 1.8 0.4 0.3 -0.6 -1.0 -1.3 0.5 -0.3
Medication: Levothyroxine sodium 1.1 1.9 3.6 -1.4 -0.1 -0.4 1.9 1.8 -0.9 1.3 -1.8 1.4
Sitting height 0.1 0.7 2.3 -0.2 0.9 0.1 -1.4 -0.3 -0.2 0.6 1.5 0.8
Chronic bronchitis/emphysema (father) 0.6 0.7 1.8 -0.4 -0.8 0.3 -0.8 -0.8 0.5 -1.2 1.3 -1.1
High blood pressure (mother) 0.3 0.4 1.2 -0.9 0.3 -0.4 -0.3 0.0 -1.1 0.7 -0.3 -0.6
Body mass index (BMI) 0.4 1.9 4.3 -0.9 0.7 1.5 1.6 1.3 -1.0 1.7 -1.1 2.1
Impedance of leg (left) 0.4 1.9 10.2 1.1 -1.2 -3.2 1.3 0.6 0.4 -0.2 -1.6 -0.1
Leg predicted mass (left) 0.2 1.2 2.8 -1.3 1.1 1.7 -0.3 0.4 -1.2 1.0 0.7 1.4
Trunk fat mass 0.3 1.1 2.3 -1.0 -0.1 0.4 1.2 1.2 -1.1 1.2 -0.8 1.5
Waist circumference 0.4 1.3 3.7 -1.2 0.7 1.0 0.8 1.2 -1.0 1.3 -0.6 1.9
Number of incorrect matches in round 0.6 1.0 5.5 -0.3 -2.4 -0.7 -0.0 -1.1 -0.9 -0.3 -0.2 -0.8
Past tobacco smoking 0.4 0.7 2.5 0.8 0.6 -1.6 0.2 0.6 -0.0 1.0 -1.0 0.0
Alcohol usually taken with meals 1.0 1.5 3.8 1.9 0.1 1.1 -0.6 -1.4 1.8 -1.5 0.8 -0.7
Nervous feelings 0.1 0.3 0.7 -0.3 -0.1 -0.4 -0.8 -0.1 0.0 -0.6 0.8 -0.7
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.7 3.5 1.0 0.1 -1.9 -0.1 -0.3 -0.7 -0.4 -0.2 -1.1
Hearing difficulty/problems with background noise 0.8 1.3 2.9 -0.5 -0.9 -0.4 1.6 1.2 -1.1 1.2 -1.7 0.8
Hair/balding pattern: Pattern 2 0.6 0.8 1.6 -1.1 -0.9 -0.5 0.3 1.1 -1.0 1.2 -0.5 0.9
Had menopause 0.8 1.0 3.7 -0.8 -1.9 1.9 -0.8 -0.1 -0.4 -0.3 0.4 0.1
Had other major operations 1.7 2.1 6.2 -1.2 0.4 -2.5 0.9 1.9 -1.2 1.4 -1.5 1.0
Forced vital capacity (FVC) 0.3 1.0 4.7 0.0 0.4 0.8 -2.2 -0.1 -0.0 -0.0 1.8 0.5
Heel bone mineral density (BMD) T-score, automated (right) 2.3 5.2 10.3 3.2 -0.5 1.5 -2.3 -2.9 2.1 -2.4 2.1 -2.5
Ever unenthusiastic/disinterested for a whole week 1.6 1.9 3.6 -0.3 0.8 -0.0 1.9 1.9 -1.3 1.5 -1.5 1.8
Qualifications: None of the above 0.1 0.2 0.5 -0.4 -0.0 -0.2 -0.2 0.5 -0.7 0.6 0.5 0.3
Financial difficulties in last 2 years 1.3 1.7 4.7 -0.8 -0.9 0.1 2.0 1.9 -1.0 0.8 -2.2 0.8
Mouth/teeth dental problems 0.7 1.0 3.6 0.5 -0.4 -0.4 -0.6 -1.8 0.2 -1.2 0.2 -1.9
Heart attack 0.3 0.4 1.2 0.6 1.0 0.5 -0.2 0.1 0.4 -1.1 0.6 -0.2
Allergy 0.5 1.2 4.5 2.1 0.5 -1.0 1.3 0.7 1.3 0.3 -1.1 0.3
Pain all over the body in last month 0.7 0.8 4.2 -0.8 -0.1 -0.3 -0.5 0.5 -2.1 1.1 -0.2 0.4
Diabetes (self-reported) 0.4 0.6 1.7 -0.8 -0.6 -0.4 -1.0 -1.3 -0.3 -0.6 0.7 -0.3
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 4.5 0.6 0.2 2.1 -0.7 0.2 0.6 0.3 0.9 0.2
Medication: Ramipril 1.4 1.8 5.0 2.2 0.8 1.0 -1.0 -0.7 1.6 -1.8 1.3 -0.7
Medication: Simvastatin 2.0 3.0 6.0 -1.6 -1.3 -0.3 -1.6 -2.3 -1.5 -2.5 1.1 -2.3
Fluid intelligence score 0.2 0.4 0.9 0.1 -0.0 0.9 -1.0 -0.5 -0.2 -0.7 0.8 -0.5
Illnesses of siblings 1.2 1.7 2.8 -1.3 -1.6 -1.4 1.1 0.6 -1.4 1.1 -1.7 1.2
Neuroticism score 0.2 0.5 2.3 0.2 -1.1 -0.4 -0.1 -0.4 -0.2 -0.6 -0.0 -1.5
Weight 0.3 1.6 4.2 -1.2 0.7 0.9 1.0 1.1 -1.4 1.6 -0.5 2.1
Impedance of arm (right) 0.2 0.8 3.3 0.6 -0.7 -1.8 -0.7 -0.2 0.8 -1.2 0.3 -0.9
Arm fat percentage (right) 0.3 1.1 2.8 -0.6 0.8 0.9 1.1 1.1 -0.3 1.2 -0.9 1.7
Trunk fat-free mass 0.2 1.0 2.2 -1.2 1.1 1.1 -0.3 -0.0 -1.2 1.1 0.6 1.5
Hip circumference 0.7 3.1 6.6 -1.3 0.9 0.3 1.8 2.1 -1.7 2.5 -1.5 2.6
Time employed in main current job 0.4 0.4 1.4 1.2 -0.0 -1.1 0.1 -0.4 0.8 -0.4 0.0 -0.3
Alcohol intake versus 10 years previously 0.4 0.6 1.9 0.4 1.4 1.3 -0.1 0.1 0.5 0.2 0.6 0.9
Father’s age at death 0.7 0.9 2.5 0.3 1.6 1.1 -0.8 -0.9 1.2 -0.3 1.1 -0.6
Worrier / anxious feelings 0.6 1.1 3.9 1.2 -0.5 0.3 -0.7 -1.0 1.0 -1.2 0.6 -2.0
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 1.9 0.4 -0.4 -0.3 -0.7 -0.2 0.2 -0.9 0.9 -1.4
Falls in the last year 1.0 1.4 7.4 -2.7 -0.3 0.2 0.3 0.5 -0.9 1.2 -0.9 1.3
Hair/balding pattern: Pattern 3 1.5 2.2 5.9 1.1 -2.3 -1.0 0.2 -1.3 1.1 -1.9 -0.1 -2.4
Number of live births 0.3 0.5 2.5 0.5 -0.3 1.6 -0.7 -0.1 0.9 -0.1 0.5 0.0
Forced expiratory volume in 1-second (FEV1) 0.3 1.1 3.3 -0.6 0.8 -0.3 -0.1 1.3 -1.1 1.4 -0.4 1.8
Pulse rate 1.9 3.2 6.3 -0.9 -0.2 -2.0 2.4 1.8 -1.1 2.0 -2.5 2.0
Happiness 2.4 2.9 7.2 1.0 -1.8 2.7 -1.4 -0.7 0.8 -2.1 2.0 -1.8
Noisy workplace 1.5 1.9 4.5 -1.4 1.1 -1.0 0.9 2.1 -2.0 1.4 -1.1 0.5
Qualifications: A levels/AS levels or equivalent 0.5 1.1 5.2 -0.1 0.4 2.3 -0.8 0.2 1.6 -0.4 0.9 -0.2
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.5 2.5 -0.5 1.6 -1.3 -0.4 0.1 -0.2 0.3 0.1 0.3
Mouth/teeth dental problems: Dentures 0.7 1.2 3.4 -0.7 0.4 -0.9 1.1 1.9 -0.9 1.0 -1.1 1.3
Asthma 1.8 3.5 6.7 -2.2 0.4 1.8 -2.6 -1.9 -1.6 -1.6 2.6 -0.7
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 2.2 1.3 1.5 -0.1 -0.1 0.1 0.6 0.1 0.0 0.2
Medication: Cholesterol lowering 1.6 2.5 8.2 -0.7 -1.5 1.4 -1.3 -2.0 0.2 -2.9 1.4 -1.4
Depression (self-reported) 0.2 0.3 0.6 0.8 -0.2 -0.7 0.4 -0.4 -0.3 -0.7 -0.5 0.3
Medication: Lansoprazole 0.6 0.7 2.0 -0.1 0.4 0.1 1.1 0.5 1.2 0.6 -1.4 1.0
Prospective memory result 0.4 0.5 1.4 0.3 -0.4 0.5 -0.7 -0.8 0.4 -0.8 1.2 -0.7
Lung cancer (father) 0.4 0.5 1.5 1.2 -0.6 -0.2 0.7 0.6 -0.5 0.9 -0.7 0.3
Illnesses of mother 1.2 1.5 3.4 0.6 1.6 0.1 1.6 1.1 0.8 0.8 -1.3 1.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.4 4.6 -1.3 0.6 -0.3 0.0 1.5 -2.1 1.3 -0.5 1.3
Pulse wave Arterial Stiffness index 2.9 3.4 8.6 1.7 2.1 0.9 1.2 1.9 1.2 2.7 -0.8 2.9
Impedance of arm (left) 0.1 0.6 4.0 0.6 -0.6 -2.0 -0.1 0.6 0.3 -0.3 -0.4 -0.5
Arm fat mass (right) 0.3 1.4 3.9 -0.7 0.8 1.0 1.2 1.2 -0.8 1.6 -0.8 2.0
Trunk predicted mass 0.2 1.0 2.2 -1.3 1.1 1.1 -0.4 -0.0 -1.2 1.1 0.6 1.5
Standing height 0.1 0.6 1.2 -0.7 0.3 -1.0 -1.1 -0.1 -0.9 0.2 1.1 0.5
Length of working week for main job 0.4 0.4 1.9 -0.0 0.3 -0.7 -0.4 -0.3 -0.3 -1.0 0.4 -1.4
Exposure to tobacco smoke at home 0.3 0.3 0.8 0.9 0.3 -0.5 0.8 0.2 0.5 -0.1 -0.3 0.6
Breastfed as a baby 1.4 1.8 3.9 1.9 1.8 1.6 0.7 -0.2 2.0 0.2 -0.3 1.3
Tense / ‘highly strung’ 0.4 0.6 1.7 -0.4 -0.2 -1.3 0.9 0.4 -1.2 0.2 -0.9 -0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 0.8 -0.2 0.9 0.7 0.0 0.6 0.2 0.6 -0.5 0.5
Hair/balding pattern: Pattern 4 0.5 1.3 3.8 -0.0 1.9 1.0 -1.9 -0.0 0.2 -0.5 1.6 -0.4
Birth weight of first child 0.4 0.7 2.2 1.4 0.8 0.1 -0.1 -0.5 1.5 -0.8 0.4 -0.6
Peak expiratory flow (PEF) 1.7 4.0 10.0 -1.6 2.0 -0.2 1.0 2.1 -2.1 2.6 -1.7 3.2
Pulse wave reflection index 1.5 1.9 3.9 2.0 1.9 1.0 0.3 1.1 0.9 1.8 -0.2 1.6
Ever highly irritable/argumentative for 2 days 1.3 1.6 5.4 -0.4 0.5 0.5 0.8 1.3 -1.2 2.3 -0.8 2.0
Loud music exposure frequency 0.3 0.3 1.5 -1.2 0.4 0.2 0.2 0.3 -0.9 -0.1 0.2 0.6
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 1.9 0.2 1.4 -0.2 1.3 0.2 0.5 -0.6 -0.4 -0.7
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 2.4 -0.8 -1.6 1.4 0.2 0.5 -0.3 0.6 -0.2 -0.2
Blood clot in the leg (DVT) 0.4 0.5 1.6 -0.6 0.6 0.4 0.5 0.6 -1.0 0.7 -0.6 1.3
Medication: Paracetamol 0.3 0.5 1.5 -1.0 -0.7 -0.3 1.2 -0.1 -0.2 -0.9 -1.0 0.1
Headache pain in last month 1.0 1.6 3.4 0.9 -1.6 -1.8 1.3 1.3 0.3 1.2 -1.8 0.3
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 2.1 0.6 0.1 -1.4 -0.3 0.2 -0.2 1.4 -0.2 -0.2
Glaucoma (self-reported) 1.4 1.6 3.4 -1.1 -1.4 0.3 -1.1 -1.8 -0.6 -1.6 1.4 -1.5
Gout (self-reported) 0.5 0.7 1.5 -1.2 0.4 0.2 -1.2 -1.1 -0.0 -0.9 0.9 -0.9
Hypothyroidism/myxoedema (self-reported) 1.8 3.6 7.1 -1.6 0.2 -1.1 2.7 2.2 -1.5 1.8 -2.5 2.2
Medication: Amlodipine 0.1 0.1 0.6 0.6 0.5 -0.1 0.1 -0.1 0.8 0.3 0.2 -0.2
Medication: Ventolin 100micrograms inhaler 1.9 2.4 6.6 -0.6 1.6 2.6 -2.1 -1.5 0.7 -1.0 2.1 0.1
Birth weight 0.8 1.7 3.6 -1.7 -1.9 0.1 -1.0 -1.0 -1.4 -1.1 0.7 -1.9
Chronic bronchitis/emphysema (mother) 2.3 2.7 6.7 0.3 -1.5 1.2 -1.7 -1.4 1.4 -1.9 1.9 -2.6
High blood pressure (siblings) 0.3 0.4 1.3 0.8 1.0 1.2 0.3 0.2 0.6 -0.1 0.1 0.1
Forced vital capacity (FVC), Best measure 0.3 1.0 3.1 -1.1 0.3 0.5 -1.8 0.0 -1.6 0.0 1.2 0.3
Body fat percentage 0.4 1.5 3.0 -0.9 -0.4 0.2 1.7 1.5 -0.9 1.3 -1.4 1.5
Leg fat percentage (right) 0.9 3.2 7.3 -1.6 -1.1 -0.7 2.7 1.7 -1.6 1.7 -2.5 1.6
Arm fat-free mass (right) 0.2 1.0 2.4 -0.8 1.0 1.2 0.3 0.6 -1.2 1.3 0.1 1.6
Exposure to tobacco smoke outside home 0.5 0.6 2.5 1.1 0.4 0.1 -0.4 -0.6 1.6 -0.1 1.0 -0.1
Comparative body size at age 10 0.7 1.9 6.8 -2.6 0.0 0.8 0.4 1.6 -1.7 1.4 -0.2 1.3
Number of full brothers 0.8 1.0 5.1 0.1 -2.2 0.1 -0.2 -0.9 -0.7 -0.8 0.2 -1.4
Worry too long after embarrassment 0.7 1.2 5.4 -0.2 -2.3 -1.6 -0.2 0.6 -0.9 0.6 -0.3 -1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 1.1 -0.5 0.0 -1.1 -0.3 0.1 -0.1 0.5 -0.1 -0.2
Wheeze or whistling in the chest in last year 0.5 1.0 5.1 -1.1 2.3 -0.1 -0.8 0.2 -0.9 -0.1 0.9 0.2
Number of children fathered 2.0 2.3 6.9 -2.6 0.1 1.1 0.3 0.8 -2.6 1.3 -0.9 1.4
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 0.8 -0.5 0.5 0.4 -0.8 -0.2 -0.1 -0.1 0.9 -0.2
Age at first live birth 0.3 0.5 1.8 -0.2 0.7 -0.7 0.2 -1.3 0.1 -1.1 0.0 0.3
Pulse wave peak to peak time 2.8 3.3 7.8 -1.7 -2.0 -1.0 -1.3 -1.8 -1.2 -2.7 0.9 -2.8
Health satisfaction 0.2 0.2 0.7 0.3 -0.7 0.8 -0.5 -0.2 -0.0 0.4 0.3 -0.3
Shortness of breath walking on level ground 0.4 0.5 2.0 0.6 -0.1 -1.4 0.2 0.6 -0.2 0.5 -0.5 -1.1
Qualifications: College or University degree 0.4 1.4 2.8 0.9 1.6 0.9 -1.7 -1.0 1.2 -0.8 1.5 0.3
Eye problems/disorders: None of the above 1.1 1.3 3.0 0.5 -0.2 0.4 1.7 1.2 0.4 1.2 -1.6 1.7
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.6 0.7 0.8 1.0 -0.2 0.2 1.3 0.6 0.4 0.9
Emphysema/chronic bronchitis 1.4 1.5 4.8 0.8 -1.6 -0.3 -1.2 -1.1 0.9 -1.2 0.8 -2.2
Medication for pain relief, constipation, heartburn 0.2 0.3 1.2 0.5 0.5 -0.4 -0.6 -0.1 1.1 0.6 0.5 -0.2
Neck or shoulder pain in last month 0.9 1.3 4.3 1.3 0.5 -0.1 2.1 0.8 1.0 0.3 -1.8 0.6
Medication: Blood pressure 0.5 0.8 3.1 0.3 1.1 0.3 1.8 1.1 0.6 -0.1 -0.6 1.0
Angina (self-reported) 1.0 1.4 3.6 -0.5 -0.8 1.0 -1.4 -1.3 -0.7 -1.9 1.3 -1.0
Migraine (self-reported) 0.9 1.1 2.1 -0.2 -1.1 -1.2 -1.1 -1.1 -1.0 -1.4 0.4 -1.3
Medication: Ibuprofen 0.4 0.5 2.8 0.7 1.7 -0.2 -0.5 0.1 0.3 0.3 0.5 0.5
Medication: Allopurinol 0.7 0.9 2.0 -1.4 -0.7 -1.3 1.0 0.3 -0.9 0.5 -1.2 -0.0
Medication: Omeprazole 0.9 1.1 3.1 -1.8 -1.4 -0.6 0.5 0.6 -1.7 0.2 -0.9 -0.1
Medication: Seretide 50 evohaler 0.6 0.7 1.6 -1.1 0.7 0.8 -1.2 -0.9 -0.3 -0.3 0.9 -0.0
Mean time to correctly identify matches 0.0 0.1 0.4 0.2 0.2 -0.0 -0.1 0.3 0.0 0.6 0.1 0.0
Heart disease (mother) 0.4 0.4 1.3 0.4 -1.2 0.9 -0.4 1.0 0.3 0.6 -0.0 0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.8 0.9 0.9 0.3 0.1 -0.2 1.3 -0.7 -0.1 0.5
Whole body fat mass 0.3 1.3 2.3 -1.0 -0.2 0.5 1.5 1.2 -1.1 1.3 -1.1 1.5
Leg fat mass (right) 0.5 2.0 4.2 -1.3 -0.0 -0.0 2.0 1.4 -1.5 1.6 -1.6 1.8
Arm predicted mass (right) 0.2 1.2 3.0 -0.8 1.0 1.1 0.3 0.7 -1.4 1.5 0.0 1.7
Pulse rate, automated reading 0.9 2.7 5.7 -1.5 -1.8 -0.9 2.4 1.2 -1.2 1.7 -2.3 1.3
Alcohol intake frequency. 0.2 0.4 0.6 0.5 0.6 0.6 -0.4 -0.7 0.6 -0.8 0.8 -0.2
Comparative height size at age 10 0.4 2.0 4.5 -1.9 -1.1 -1.4 -0.2 1.1 -2.1 1.9 -0.2 1.5
Number of full sisters 1.3 1.6 4.2 -0.1 -0.6 -1.9 -1.2 -1.3 0.0 -1.3 1.0 -2.0
Suffer from ‘nerves’ 0.6 0.9 3.0 -1.7 -1.1 -0.5 -0.0 -0.1 -1.7 0.2 -0.1 -0.8
Overall health rating 0.4 0.8 2.6 0.4 -0.4 -1.0 -0.3 -0.4 0.2 -1.6 0.7 -1.5
Chest pain or discomfort 1.6 2.3 5.1 1.2 0.6 1.6 -2.3 -1.3 1.6 -1.2 2.2 -0.9
Had major operations 2.2 2.6 6.5 2.5 1.3 1.7 -0.7 -1.0 2.5 -1.6 1.5 -0.3
Age at last live birth 0.9 1.3 3.3 0.7 0.0 1.4 -0.9 -1.5 1.3 -1.8 0.9 -0.7
Family relationship satisfaction 1.8 2.2 6.7 2.6 0.5 1.3 -1.2 -0.5 1.4 -1.7 1.8 -1.1
Leg pain on walking 0.6 0.8 5.2 -0.1 0.7 2.3 0.1 0.4 0.8 -0.1 0.5 0.5
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.9 5.0 -1.0 -2.2 0.4 -0.5 -0.5 -0.7 -0.3 0.6 -0.4
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.6 0.4 -0.7 -0.1 0.3 -0.3 0.1 -0.7 -0.2 -0.4
Illness, injury, bereavement, stress in last 2 years 1.0 1.2 3.2 1.8 -1.2 0.4 -0.7 -0.9 1.4 -0.9 0.6 -1.5
Medication: Aspirin 0.3 0.4 0.9 0.2 -0.5 1.0 -0.9 0.1 -0.8 -0.1 0.9 0.2
Supplements: Vitamin C 0.4 0.5 1.2 0.2 1.1 -0.1 0.9 -0.5 0.4 0.5 -1.1 0.6
Knee pain experienced in last month 0.3 0.4 2.6 -0.2 -0.7 1.6 -0.2 0.3 -0.2 -0.2 0.2 -0.3
Hypertension (Self-reported) 0.4 1.2 2.6 -0.9 0.7 0.6 1.1 1.6 -0.9 1.4 -0.6 1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.5 1.8 6.8 0.9 -0.3 -0.9 2.6 0.7 0.7 -0.0 -2.4 0.7
Illnesses of father: Heart disease 1.1 1.5 7.3 -2.0 -0.1 -0.5 -1.1 -0.2 -2.7 -0.0 1.0 0.0
Illnesses of siblings: Diabetes 0.1 0.1 0.2 0.1 0.4 -0.3 -0.4 -0.5 0.2 0.1 0.3 0.2
Smoking status: Previous 0.7 1.1 2.5 -0.2 -1.1 1.3 -0.4 -1.4 0.4 -1.6 1.3 -0.8
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.5 1.6 1.3 0.7 0.2 0.3 0.4 1.0 0.2 -0.5 1.1
Whole body fat-free mass 0.2 1.1 2.2 -1.2 1.2 1.5 -0.5 -0.0 -1.1 0.9 0.8 1.4
Leg fat-free mass (right) 0.2 1.3 3.7 -0.8 1.6 1.9 -0.6 0.2 -0.6 0.7 1.1 1.4
Arm fat percentage (left) 0.4 1.5 3.3 -0.7 0.7 0.9 1.5 1.5 -0.6 1.6 -1.2 1.8
Average weekly red wine intake 0.7 1.0 2.2 0.9 -1.5 0.1 -1.3 -1.3 1.3 -0.4 0.7 -0.1
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.7 -0.8 -0.2 -0.3 0.6 -0.8 -0.1 -0.3 0.2 0.3
Mood swings 0.3 0.5 1.2 -0.7 -0.5 -0.9 0.4 0.5 -1.1 1.0 -0.7 0.3
Loneliness, isolation 0.5 0.7 3.7 -0.7 0.7 -1.9 0.4 0.4 -0.4 0.9 -0.5 0.3
Long-standing illness, disability or infirmity 1.5 2.2 5.7 0.7 0.6 1.4 -1.9 -1.9 0.7 -2.4 1.6 -1.2
Ever had bowel cancer screening 1.4 1.6 4.2 -1.4 -2.1 -1.7 1.1 -0.0 -0.8 1.0 -1.4 0.9
Diabetes diagnosed by doctor 0.7 1.2 3.0 -1.0 -0.5 0.2 -1.7 -1.5 -1.0 -0.8 1.5 -0.6
Ever had stillbirth, spontaneous miscarriage or termination 2.7 2.9 5.5 -0.0 -1.7 1.2 -1.9 -2.4 0.4 -2.0 1.8 -2.2
Friendships satisfaction 2.3 2.8 4.8 1.9 -2.2 0.7 -1.2 -1.1 1.7 -1.9 1.7 -2.1
Qualifications: nursing, teaching 0.3 0.5 1.9 1.4 -0.0 1.1 -0.3 -0.0 0.6 -0.5 0.3 0.7
Commuting to job workplace: Walk 0.6 0.6 1.7 -1.1 1.3 -0.4 0.1 -0.1 -1.0 0.6 -0.1 0.9
Eye problems/disorders: Cataract 0.3 0.4 0.8 0.9 0.9 0.2 -0.7 0.2 0.5 -0.4 0.6 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 2.0 0.6 0.3 -1.3 1.4 0.4 0.4 0.6 -1.0 1.3
Medication for cholesterol 0.5 0.8 3.9 0.9 -0.2 1.3 0.4 -0.2 2.0 -0.5 -0.1 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.4 1.1 -0.2 0.1 -1.1 0.0 -0.7 -1.0 0.6 -0.4 0.6
Back pain experienced in last month 0.7 1.0 3.3 -1.4 -0.8 0.4 0.1 -0.5 -1.8 -1.3 -0.3 -1.0
Mineral and other dietary supplements 1.0 1.3 4.1 -0.8 0.8 1.7 -1.4 -0.6 -0.7 -0.6 2.0 -0.8
Breast cancer (self-reported) 5.1 6.0 11.8 -2.0 -1.6 -2.3 2.7 2.5 -2.8 2.6 -3.4 1.7
Asthma (self-reported) 1.5 3.1 5.4 -2.3 0.5 1.5 -2.3 -1.9 -1.8 -1.4 2.3 -0.6
Osteoporosis (self-reported) 1.5 1.8 7.9 -0.5 -0.4 -0.1 -1.5 -1.5 -0.3 -1.5 1.2 -2.8
Osteoarthritis (self-reported) 2.4 3.1 6.5 0.8 -0.3 2.2 -2.2 -1.9 1.3 -2.5 1.3 -1.9
Medication: Aspirin 0.3 0.4 1.1 0.0 -0.5 0.7 -0.9 0.0 -0.8 -0.2 1.1 0.2
Medication: Gliclazide 0.7 0.8 2.0 -1.4 -1.0 0.5 1.2 0.1 -1.4 -0.1 -0.9 -0.2
Illnesses of father: None of the above (group 1) 0.6 0.8 1.7 1.0 -0.3 -0.9 1.0 -0.0 1.1 -0.5 -1.3 -0.9
Smoking status: Current 1.7 2.7 7.8 0.3 2.1 0.6 1.5 2.0 0.6 1.9 -1.3 2.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.3 0.7 -0.8 0.8 0.4 -0.2 0.0 -0.3 0.6 -0.0 0.7
Whole body water mass 0.2 1.1 2.6 -1.0 1.2 1.6 -0.4 0.1 -1.0 0.9 0.7 1.4
Leg predicted mass (right) 0.2 1.3 3.6 -0.9 1.6 1.9 -0.6 0.2 -0.7 0.7 1.1 1.4
Arm fat mass (left) 0.4 1.7 4.2 -0.9 0.7 0.9 1.3 1.4 -0.9 1.8 -1.0 2.0
Number of self-reported non-cancer illnesses 1.0 1.7 3.0 -1.7 -1.4 1.2 -1.7 -0.7 -1.2 -1.2 1.1 -1.1
Average weekly champagne plus white wine intake 0.3 0.5 1.0 -1.0 0.9 0.9 0.1 -0.7 -0.6 -0.1 0.2 0.8
Miserableness 0.3 0.5 1.1 -0.7 0.3 -0.9 0.0 0.8 -1.1 0.8 -0.3 0.7
Guilty feelings 0.7 1.0 3.3 1.2 -1.1 -1.8 0.7 0.1 0.4 -0.9 -0.8 -1.1
Wears glasses or contact lenses 0.6 0.7 1.8 -0.7 -0.6 0.8 0.2 1.3 -0.5 1.0 -1.0 0.8
Ever taken oral contraceptive pill 0.3 0.3 0.7 -0.6 -0.7 0.8 -0.4 -0.0 -0.3 -0.8 0.7 0.2
Hearing aid user 1.2 1.3 3.6 -0.2 -0.9 1.8 -1.5 -0.5 0.2 -0.8 1.0 -1.9
Mother’s age at death 0.4 0.5 2.5 0.2 -0.7 -1.6 0.6 0.5 -0.3 0.2 -0.6 -0.6
Financial situation satisfaction 0.2 0.2 0.7 -0.2 0.1 0.6 0.4 -0.3 0.4 -0.8 -0.0 -0.7
Tinnitus: Yes, now most or all of the time 1.5 1.7 7.2 -0.2 -1.0 -0.6 2.1 1.1 -0.5 0.8 -2.7 0.8
Commuting to job workplace: Public transport 0.3 0.4 1.0 -0.8 0.3 0.7 -1.0 -0.3 0.6 0.2 0.9 0.0
Eye problems/disorders: Glaucoma 2.7 3.2 6.1 -0.9 -1.3 1.3 -1.7 -2.5 -0.0 -2.2 2.1 -2.5
Medication: Blood pressure 0.3 0.5 2.3 -0.6 0.5 0.4 -0.8 0.2 -1.5 0.7 0.8 0.0
Pain type(s) experienced in last month: Hip pain 0.4 0.5 2.3 -0.8 -1.5 0.7 -0.3 0.0 -0.8 -0.4 0.1 -0.7
Supplements: Fish oil (including cod liver oil) 2.7 3.5 8.9 0.5 -0.5 -2.7 2.5 1.5 -0.1 1.9 -3.0 1.7
High cholesterol (Self-reported) 1.7 3.1 7.9 -1.3 -2.2 0.0 -1.0 -2.2 -0.3 -2.8 0.8 -2.5
Medication: Bendroflumethiazide 0.8 1.2 2.1 1.1 0.2 0.4 -0.9 -1.4 1.3 -1.4 1.2 -1.1
Medication: Paracetamol 0.2 0.2 0.5 -0.4 0.2 0.6 0.7 0.1 0.7 -0.2 -0.6 0.5
Medication: Lisinopril 1.1 1.4 3.6 0.5 -1.1 -1.1 1.9 1.5 0.6 0.9 -1.6 0.5
Medication: Atorvastatin 0.8 1.0 3.2 -1.8 -0.1 1.7 -0.9 -0.5 0.5 -0.9 0.9 -0.3
Illnesses of father: High blood pressure 0.5 0.6 2.1 -0.6 -0.2 -0.2 -0.2 0.7 -0.7 1.2 0.3 1.5
Alcohol drinker status: Never 0.2 0.2 0.6 0.8 -0.5 -0.7 0.3 -0.2 0.3 0.1 -0.3 0.3
Ever smoked 0.6 1.1 6.6 -0.6 0.8 2.6 -0.1 0.2 0.5 -0.2 0.9 1.0
Basal metabolic rate 0.2 1.1 2.8 -1.1 1.1 1.4 -0.1 0.4 -1.2 1.2 0.4 1.7
Leg fat percentage (left) 0.7 2.7 6.8 -1.1 -0.6 -0.6 2.6 1.6 -1.1 1.8 -2.3 1.8
Arm fat-free mass (left) 0.2 0.8 2.1 -0.7 0.9 1.3 -0.2 0.0 -0.9 1.0 0.5 1.4
Number of operations (self-reported) 0.3 0.5 1.9 1.4 0.4 -0.5 -0.7 -0.3 0.9 -0.5 0.6 -0.3
Average weekly beer plus cider intake 0.2 0.4 1.0 -1.0 0.4 0.4 -0.4 0.0 0.2 -0.8 0.9 -0.5
Irritability 0.3 0.6 2.8 -0.8 1.1 1.7 0.0 0.1 -0.6 -0.1 0.2 0.4
Risk taking 0.8 1.2 3.5 -0.9 0.1 0.0 0.9 1.3 -1.9 1.3 -1.1 1.0
Ever had prostate specific antigen (PSA) test 2.1 2.5 6.2 -0.7 -0.4 -2.2 1.7 2.5 -1.3 1.7 -1.8 0.4
Fractured/broken bones in last 5 years 0.2 0.2 0.6 -0.4 -0.3 -0.1 0.3 0.4 0.3 0.5 -0.6 0.8
Age started oral contraceptive pill 0.2 0.2 0.8 -0.5 0.2 0.1 0.9 0.1 -0.5 0.4 -0.7 0.3
Diastolic blood pressure, automated reading 1.2 3.8 9.7 0.5 1.6 1.4 2.0 1.8 -0.2 3.0 -1.9 3.1
Ever depressed for a whole week 0.1 0.1 0.3 0.5 -0.3 0.4 0.4 -0.4 0.1 -0.2 -0.4 0.4
Unable to work because of sickness or disability 0.4 0.5 2.0 -0.1 0.6 0.7 0.3 -0.1 -1.1 0.7 -0.4 1.4
Commuting to job workplace: Cycle 0.4 0.5 1.8 0.6 0.4 -1.4 1.0 0.4 0.0 -0.0 -0.6 0.7
Myopia 0.2 0.3 0.9 0.6 -1.0 -0.5 -0.3 -0.1 0.3 0.8 -0.0 0.5
Vascular/heart problems diagnosed by doctor 0.1 0.2 0.6 0.4 -0.4 -0.8 -0.3 -0.7 0.4 -0.1 -0.3 -0.5
Cholesterol lowering medication 0.6 0.9 2.8 -1.7 -0.7 -0.1 -1.3 -0.6 -1.3 -0.2 0.5 -0.9
Medication: Omeprazole (e.g. Zanprol) 1.4 1.7 3.1 -1.8 -0.8 -1.0 1.5 1.3 -1.4 0.9 -1.7 0.8
Pain experienced in last month 0.7 1.2 2.8 0.8 1.2 1.7 -0.8 -0.5 1.3 0.5 1.3 1.1
Supplements: Calcium 0.3 0.4 1.0 0.4 0.1 -0.5 0.3 0.9 -0.3 0.6 -1.0 -0.7
Basal cell carcinoma (self-reported) 0.4 0.4 1.7 0.7 -1.3 0.2 -0.1 0.3 1.0 -0.2 0.1 -0.6
Heart attack/myocardial infarction (self-reported) 0.3 0.3 1.1 0.4 0.9 0.4 -0.3 0.0 0.3 -1.0 0.6 -0.1
Deep venous thrombosis (DVT) (self-reported) 0.5 0.7 1.8 -0.9 0.4 0.3 0.6 0.8 -1.2 0.6 -0.7 1.3
Heart disease (siblings) 0.8 1.0 4.7 -1.7 0.1 1.0 -0.2 -0.1 -2.2 0.5 0.2 -0.2
Alcohol drinker status: Previous 1.3 1.4 3.0 0.4 0.7 1.7 -1.1 -1.7 0.7 -1.6 1.3 -0.9
Pack years of smoking 0.6 0.8 1.8 0.3 -0.6 -0.9 -1.2 -1.1 0.6 -1.2 1.3 -0.5
Impedance of whole body 0.3 1.4 8.7 0.7 -1.1 -2.9 0.1 0.3 0.4 -0.7 -0.6 -0.8
Leg fat mass (left) 0.5 2.1 4.4 -1.1 0.2 -0.1 2.1 1.4 -1.2 1.7 -1.6 2.0
Arm predicted mass (left) 0.2 0.8 2.1 -0.6 1.1 1.4 -0.2 0.2 -0.9 0.9 0.5 1.4