Hub : Genes

STIM1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1210	0.0320	2.3e-05	0.025	0.050	0.060	0.049	0.049	4.6e-04	9.0e-07	7.9e-08	1.3e-06	1.3e-06
2	GTEx	Esophagus Muscularis	0.1200	0.0480	2.5e-03	0.008	NA	0.013	NA	0.001	1.0e-01	NA	4.8e-02	NA	2.7e-01
3	GTEx	Heart Left Ventricle	0.1745	0.0582	3.8e-04	0.092	NA	0.072	NA	0.081	1.4e-05	NA	1.2e-04	NA	4.1e-05
4	GTEx	Lung	0.1854	0.0474	2.6e-10	0.196	NA	0.183	NA	0.186	5.7e-15	NA	5.5e-14	NA	3.5e-14
5	GTEx	Thyroid	0.3260	0.0560	7.3e-15	0.276	NA	0.268	NA	0.266	3.0e-21	NA	1.2e-20	NA	1.8e-20
6	ROSMAP	Brain Pre-frontal Cortex	0.1219	0.0338	5.0e-06	0.052	0.055	0.058	0.055	0.053	2.4e-07	1.4e-07	5.9e-08	1.2e-07	1.8e-07
7	YFS	Blood	0.0251	0.0085	1.1e-05	0.021	0.015	0.020	0.017	0.020	1.2e-07	7.7e-06	2.8e-07	1.7e-06	3.4e-07
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0322	0.0150	2.2e-04	0.036	0.034	0.025	NA	0.023	6.3e-05	8.8e-05	6.6e-04	NA	1.0e-03
9	TCGA	Thyroid Carcinoma	0.1480	0.0510	1.3e-10	0.086	0.111	0.110	NA	0.097	1.0e-08	6.9e-11	7.5e-11	NA	1.2e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.1	0.2	0.6	0.2	0.6	-0.2	-0.8	0.1	0.0	-0.0	0.4	-0.6
Bipolar Disorder or Schizophrenia	0.2	0.5	1.7	0.9	0.6	0.4	0.0	-0.9	1.3	-0.6	0.2	-0.0
Depressed Affect (Nagel 2018)	0.4	0.9	2.9	-0.9	-1.1	-1.5	-0.0	-0.3	-1.7	-0.4	0.1	-0.8
Depression (Nagel 2018)	0.2	0.3	1.0	0.2	0.2	-0.9	-0.3	0.1	-0.5	-1.0	0.1	-0.6
Intelligence (Savage-Jansen 2018)	0.4	1.4	4.3	-1.4	-1.1	-0.4	-1.0	-0.6	-2.1	-1.0	0.8	-1.2
Neuroticism (Nagel 2018)	0.5	1.2	3.0	-1.2	-1.3	-1.2	-0.4	-0.2	-1.7	-0.8	0.6	-1.4
Schizophrenia (2018)	0.4	0.8	2.8	0.9	0.3	0.7	0.7	-1.2	1.7	-0.7	-0.1	0.4
Schizophrenia vs Biploar Disorder	0.8	1.0	3.5	1.4	-0.9	0.9	-0.1	-0.8	1.9	-1.2	0.4	-0.1
Worry (Nagel 2018)	0.5	1.1	3.1	-1.1	-1.0	-0.0	-0.9	-0.5	-0.9	-1.3	0.9	-1.8
Alzheimer’s Disease (in mother)	0.3	0.4	0.8	0.6	-0.6	0.8	0.5	-0.9	0.1	-0.9	-0.0	-0.4
Alzheimer’s Disease (in father)	0.7	0.8	1.8	-0.3	1.1	-1.0	1.3	0.8	0.4	0.9	-1.0	0.4
Alzheimer’s Disease (including proxy)	0.2	0.3	1.2	0.6	-0.0	0.4	0.8	-0.3	1.1	-0.2	-0.2	-0.2
Crohns Disease (2017)	0.4	0.9	3.8	-0.4	0.2	1.0	-1.9	-0.3	0.1	-0.2	1.6	-0.3
Irritable Bowel Disease (IBD)	0.7	1.6	5.0	-2.2	-1.5	0.6	-1.4	-0.2	-1.1	-0.7	1.3	-0.9
Ulcerative Colitis (UC)	0.6	1.1	4.0	-1.9	-2.0	-0.6	0.1	0.3	-0.9	-0.5	0.1	-0.9
Major Depression (MDD)	0.4	0.4	2.3	1.1	0.1	-0.2	-0.1	-1.5	0.4	-0.3	0.1	0.4
Reaction Time	0.1	0.2	0.6	0.4	0.4	-0.8	-0.5	-0.1	0.1	0.3	0.4	-0.3
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.7	-1.3	-0.6	-0.2	-0.7	-1.0	-1.2	-0.3	0.5	-0.2
Breast Cancer	0.9	2.1	3.9	1.4	1.9	2.0	-1.7	-0.5	1.4	-0.3	1.8	0.9
Ovarian Cancer	0.8	1.1	5.1	-2.3	0.3	0.1	-0.9	-0.6	-1.7	0.3	0.3	0.5
Prostate Cancer	1.1	1.6	2.6	1.5	1.6	-0.2	1.6	0.6	1.0	1.3	-1.4	1.2
Age at First Birth	0.5	0.8	2.8	-0.7	-0.4	-0.8	-1.3	-0.1	-1.7	-0.1	1.0	-0.4
Bipolar Disorder (2011)	0.8	0.8	2.3	-1.5	0.3	-0.7	1.0	0.6	-1.0	0.5	-0.8	1.0
Body Mass Index (BMI) (2010)	1.1	1.5	4.1	-0.3	2.0	1.8	0.9	1.1	-0.1	1.3	-0.4	1.5
Coronary Artery Disease (CAD)	0.7	0.9	2.6	0.1	-0.5	-1.5	-1.0	0.2	-1.6	-0.4	0.2	-1.3
Crohns Disease (2012)	0.4	0.7	3.2	0.2	-0.4	0.5	-1.8	-0.6	-0.0	-0.0	1.6	-0.0
Mean Putamen Volume	0.6	0.7	2.6	1.3	-0.6	-0.5	0.7	1.6	0.2	0.6	-0.4	0.6
Fasting Glucose	3.2	3.8	11.4	2.8	2.1	2.9	0.3	0.9	3.4	0.6	0.8	0.6
HbA1C	0.6	0.7	2.0	1.4	-1.1	-0.4	1.0	-0.2	0.9	-0.3	-0.7	-0.4
HDL Cholesterol	0.7	1.1	2.8	-1.0	-0.1	0.1	1.3	1.3	-1.5	0.7	-1.7	0.4
LDL Cholesterol	0.2	0.3	0.9	-0.4	0.3	-0.3	-0.9	-0.5	-0.8	-0.2	0.5	-0.9
Lupus	0.3	0.5	1.0	-0.5	-0.9	-1.0	0.4	0.7	-0.4	0.7	-0.9	0.3
Neuroticism (2016)	0.5	0.7	2.5	0.1	-1.6	-1.3	0.0	0.1	-0.3	-0.4	0.0	-1.2
Primary Biliary Cirrhosis	0.3	0.5	1.4	-1.2	0.2	-0.4	-0.1	0.8	-1.0	0.8	-0.2	-0.2
Rheumatoid Arthritis	2.6	3.6	13.0	-0.4	0.8	-3.6	2.3	2.1	-1.8	1.0	-2.1	0.8
Schizophrenia (2014)	0.3	0.7	1.5	1.2	0.4	0.4	1.2	-0.8	1.1	-0.2	-0.6	0.8
Triglycerides	0.8	1.2	5.1	1.4	0.1	0.3	-0.8	-1.5	2.2	-0.5	0.7	-0.6
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.6	1.1	-1.3	-1.1	-0.9	-1.0	0.2	-0.8	0.4	-1.3
Ulcerative Colitis	0.3	0.5	2.4	-1.5	-1.0	-0.1	0.1	-0.1	-0.6	-0.5	0.2	-0.4
Blood Eosinophil Count	0.3	2.1	9.4	-2.6	0.9	0.6	-0.3	1.0	-3.1	0.3	0.3	0.8
Blood Platelet Count	1.0	11.0	17.6	-3.4	-2.0	0.8	-4.0	-3.4	-2.9	-4.0	3.8	-4.2
Blood Red Count	0.3	2.5	6.6	-0.8	-0.5	-2.1	1.4	2.0	-1.4	2.6	-1.6	0.1
Blood White Count	0.2	1.1	6.5	-1.7	0.2	0.2	-0.2	0.3	-2.5	0.5	-0.1	0.8
Heel T-Score	0.4	3.0	12.1	3.5	0.0	2.2	-1.2	-0.7	2.6	0.2	1.1	-0.7
BMI	0.3	1.9	3.7	-1.0	0.4	1.1	1.5	1.4	-1.7	1.9	-0.9	1.9
Height	0.1	1.1	3.4	-1.3	-0.8	-1.3	-1.0	0.3	-1.8	-0.1	1.0	0.5
Waist Hip Ratio (WHR)	0.2	0.7	1.4	-1.1	0.4	1.2	-0.8	-0.6	0.4	-1.1	1.1	-0.2
Systolic Blood Pressure	0.4	2.1	9.5	0.6	3.1	0.4	0.9	0.8	0.6	1.3	-0.2	2.3
Smoking Status	0.4	0.8	2.4	-1.2	0.4	1.3	1.3	0.4	0.1	0.2	-0.3	1.6
Allergy or Eczema	0.2	0.6	3.3	-1.8	-0.5	0.2	0.1	0.5	-0.9	0.8	-0.2	0.6
Cardiovascular Disease	0.1	0.5	3.3	-0.5	0.0	1.8	-0.0	0.3	0.1	-0.3	0.6	0.0
Hypothyroidism (self reported)	0.7	1.6	3.6	-1.9	-0.7	-0.7	1.3	1.3	-1.5	1.0	-1.3	1.0
Respiratory disease	1.6	3.7	7.9	-1.2	-0.0	1.4	-2.8	-2.6	-1.4	-2.0	2.7	-1.3
Type 2 Diabetes (T2D) (2018)	0.9	1.7	4.9	1.0	0.1	-0.2	-1.9	-2.2	0.8	-1.2	1.5	-1.1
Lung FEV1/FVC ratio	3.0	15.2	40.2	0.2	1.1	-2.4	6.3	4.4	-0.6	4.5	-5.9	4.0
Lung FVC	0.9	4.6	11.8	-1.4	-1.2	2.5	-3.3	-1.2	0.1	-1.8	3.4	-2.0
Neuroticism	0.9	2.3	7.4	-0.7	-2.4	-0.4	-1.3	-1.0	-0.6	-1.5	1.1	-2.7
Chronotype (morning person)	0.7	1.6	4.5	-1.1	0.6	-1.1	2.1	0.1	-1.6	0.3	-1.8	0.9
Hair Pigment	0.1	2.0	8.0	2.8	0.6	0.9	0.5	-0.9	2.3	-1.3	0.2	-0.7
Tanning	0.2	2.2	9.3	0.8	0.6	3.0	-1.7	0.3	1.3	0.6	1.8	1.3
Hand grip strength (left)	0.2	0.5	1.7	-0.9	0.7	-0.9	0.1	-0.0	-1.3	0.6	0.2	0.5
Number of treatments/medications taken	0.4	0.8	1.9	-0.2	-0.5	0.3	-1.3	-0.7	-0.8	-1.4	0.9	-1.1
Average weekly spirits intake	1.5	1.9	9.9	-3.1	-1.0	0.5	-0.1	0.7	-2.1	0.7	-0.5	-0.1
Sensitivity / hurt feelings	1.1	2.0	6.8	-0.0	-1.0	-0.9	-0.9	-2.6	-0.0	-1.4	0.5	-2.4
Frequency of depressed mood in last 2 weeks	0.9	1.2	3.6	-0.3	0.7	-1.9	1.1	1.4	-0.6	0.9	-1.3	0.9
Hearing difficulty/problems: Yes	0.4	0.6	3.2	0.3	-1.8	1.0	0.2	0.4	0.7	0.0	-0.0	0.1
Relative age of first facial hair	0.3	0.6	2.1	-1.4	-0.5	0.4	1.1	0.8	-0.7	0.4	-0.6	0.7
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	3.7	-1.9	1.1	0.5	0.8	1.1	-1.4	1.5	-1.5	1.7
Ever used hormone-replacement therapy (HRT)	1.2	1.6	3.4	-0.5	-1.4	-0.4	1.2	1.5	-1.8	1.0	-1.3	1.4
Ever had hysterectomy (womb removed)	1.1	1.3	4.2	1.2	-0.6	1.4	-2.0	-0.3	-0.3	-0.3	1.5	-0.9
Systolic blood pressure, automated reading	0.5	1.6	4.5	0.3	1.6	0.3	1.0	1.2	-0.2	1.9	-0.8	2.1
Eye problems/disorders: Diabetes related eye disease	1.6	1.7	3.6	-1.3	0.4	-1.0	-1.7	-1.8	0.2	-1.4	1.9	-0.7
Angina	0.9	1.1	2.8	-0.3	-0.5	1.0	-1.4	-1.1	-0.6	-1.7	1.3	-0.8
Medication for hormone replacement therapy	1.0	1.1	6.7	-0.5	-0.6	-2.6	0.3	0.8	-1.2	0.2	-0.3	-0.1
Vitamin and mineral supplements	0.7	1.0	4.1	-1.5	-0.8	-1.1	0.4	0.6	-2.0	-0.2	-0.1	-0.5
Supplements: Zinc	1.1	1.2	4.3	1.8	-0.7	1.2	-0.1	-0.5	2.1	-0.7	0.7	-0.5
Medication: Co-codamol	0.9	1.0	3.2	0.9	-0.9	1.4	-0.2	-1.0	0.8	-1.8	0.7	-0.7
Medication: Metformin	0.6	0.8	2.9	-0.8	-0.5	-0.6	-0.9	-1.7	-0.6	-0.8	0.9	-0.3
Diabetes (father)	0.4	0.5	2.7	0.6	-0.4	1.6	0.8	0.0	0.2	-0.2	-0.2	0.1
Diabetes (mother)	1.0	1.3	2.8	-0.1	-1.4	-0.8	-1.5	-0.9	-1.2	-0.6	1.4	-1.7
Severe depression (siblings)	1.4	1.5	3.6	0.1	0.4	0.6	-1.6	-1.0	0.4	-1.7	1.7	-1.9
Pack years adult smoking proportion	0.2	0.4	0.9	0.3	-0.1	-0.8	-1.0	-0.4	0.6	-0.6	0.9	-0.1
Impedance of leg (right)	0.5	2.4	11.5	0.2	-1.8	-3.4	1.4	0.7	-0.5	-0.0	-1.9	-0.3
Leg fat-free mass (left)	0.2	1.2	2.7	-1.3	1.2	1.6	-0.4	0.3	-1.2	0.9	0.8	1.3
Trunk fat percentage	0.3	1.0	2.0	-0.8	-0.4	0.2	1.3	1.4	-0.9	1.0	-1.0	1.4
Hand grip strength (right)	0.1	0.3	0.9	-0.3	0.1	-0.3	-0.8	-0.6	-0.0	-0.6	0.9	-0.2
Townsend deprivation index at recruitment	0.4	0.5	1.1	-0.4	0.0	0.5	-0.9	-0.9	0.3	-1.1	1.0	-0.5
Current tobacco smoking	1.1	1.9	5.5	0.6	1.8	0.6	0.9	1.6	0.7	1.5	-0.9	2.4
Average weekly fortified wine intake	0.9	1.0	3.0	0.9	-0.8	-0.1	-1.7	-1.6	0.8	-0.6	0.9	-0.8
Maternal smoking around birth	0.5	0.7	1.7	0.4	0.9	1.3	-0.8	0.7	0.8	0.9	-0.1	1.3
Fed-up feelings	0.3	0.5	1.2	-0.0	-0.5	-1.1	-0.7	-0.7	-0.8	-0.8	0.8	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.8	0.7	0.7	-1.3	1.2	1.7	0.1	0.8	-1.5	1.3
Relative age voice broke	0.2	0.3	1.2	-0.8	1.1	0.1	-0.3	-0.6	-0.5	0.1	0.5	0.1
Taking other prescription medications	0.3	0.4	1.2	-1.1	-1.1	0.2	-0.3	0.5	-0.7	0.6	-0.2	0.2
Age when periods started (menarche)	0.2	0.5	2.1	1.4	-0.2	-1.2	-0.0	0.5	0.4	-0.5	-0.1	-0.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.4	1.2	-0.6	0.4	-0.6	0.8	-0.7	0.6	0.3	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.2	10.8	3.3	-0.4	2.1	-2.0	-2.0	2.2	-1.6	1.9	-1.8
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.8	-1.2	-0.8	-0.7	0.4	0.3	-1.1	-1.3	0.3	-0.9
Qualifications: CSEs or equivalent	0.3	0.5	1.7	0.3	0.4	-0.8	-0.7	0.2	-0.2	-1.0	0.2	-1.3
Serious illness, injury or assault to yourself	0.2	0.2	0.6	0.0	0.8	-0.3	0.3	-0.4	-0.4	-0.3	-0.4	0.6
High blood pressure	0.3	0.9	2.2	-0.9	0.8	0.6	0.8	1.5	-0.9	1.1	-0.3	1.2
Hayfever, allergic rhinitis or eczema	0.3	0.6	3.1	-1.8	-0.2	0.4	-0.0	0.3	-1.2	0.8	0.0	0.5
Multivitamins +/- minerals	1.0	1.2	4.1	1.9	0.5	1.0	-1.0	-0.7	2.0	-0.0	0.9	-0.4
Stomach or abdominal pain in last month	0.7	0.9	4.5	1.2	2.1	-0.9	-0.1	0.2	0.6	0.0	0.1	0.8
Supplements: Glucosamine	0.5	0.7	1.8	-0.7	-1.3	-1.3	-0.1	-0.7	-0.0	-0.9	-0.4	-0.8
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.2	0.5	0.7	-1.0	0.3	-1.1	0.1	-0.2	-0.4	0.3
Medication: Atenolol	0.6	0.8	3.1	-0.8	1.8	0.4	0.3	-0.6	-1.0	-1.3	0.5	-0.3
Medication: Levothyroxine sodium	1.1	1.9	3.6	-1.4	-0.1	-0.4	1.9	1.8	-0.9	1.3	-1.8	1.4
Sitting height	0.1	0.7	2.3	-0.2	0.9	0.1	-1.4	-0.3	-0.2	0.6	1.5	0.8
Chronic bronchitis/emphysema (father)	0.6	0.7	1.8	-0.4	-0.8	0.3	-0.8	-0.8	0.5	-1.2	1.3	-1.1
High blood pressure (mother)	0.3	0.4	1.2	-0.9	0.3	-0.4	-0.3	0.0	-1.1	0.7	-0.3	-0.6
Body mass index (BMI)	0.4	1.9	4.3	-0.9	0.7	1.5	1.6	1.3	-1.0	1.7	-1.1	2.1
Impedance of leg (left)	0.4	1.9	10.2	1.1	-1.2	-3.2	1.3	0.6	0.4	-0.2	-1.6	-0.1
Leg predicted mass (left)	0.2	1.2	2.8	-1.3	1.1	1.7	-0.3	0.4	-1.2	1.0	0.7	1.4
Trunk fat mass	0.3	1.1	2.3	-1.0	-0.1	0.4	1.2	1.2	-1.1	1.2	-0.8	1.5
Waist circumference	0.4	1.3	3.7	-1.2	0.7	1.0	0.8	1.2	-1.0	1.3	-0.6	1.9
Number of incorrect matches in round	0.6	1.0	5.5	-0.3	-2.4	-0.7	-0.0	-1.1	-0.9	-0.3	-0.2	-0.8
Past tobacco smoking	0.4	0.7	2.5	0.8	0.6	-1.6	0.2	0.6	-0.0	1.0	-1.0	0.0
Alcohol usually taken with meals	1.0	1.5	3.8	1.9	0.1	1.1	-0.6	-1.4	1.8	-1.5	0.8	-0.7
Nervous feelings	0.1	0.3	0.7	-0.3	-0.1	-0.4	-0.8	-0.1	0.0	-0.6	0.8	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	3.5	1.0	0.1	-1.9	-0.1	-0.3	-0.7	-0.4	-0.2	-1.1
Hearing difficulty/problems with background noise	0.8	1.3	2.9	-0.5	-0.9	-0.4	1.6	1.2	-1.1	1.2	-1.7	0.8
Hair/balding pattern: Pattern 2	0.6	0.8	1.6	-1.1	-0.9	-0.5	0.3	1.1	-1.0	1.2	-0.5	0.9
Had menopause	0.8	1.0	3.7	-0.8	-1.9	1.9	-0.8	-0.1	-0.4	-0.3	0.4	0.1
Had other major operations	1.7	2.1	6.2	-1.2	0.4	-2.5	0.9	1.9	-1.2	1.4	-1.5	1.0
Forced vital capacity (FVC)	0.3	1.0	4.7	0.0	0.4	0.8	-2.2	-0.1	-0.0	-0.0	1.8	0.5
Heel bone mineral density (BMD) T-score, automated (right)	2.3	5.2	10.3	3.2	-0.5	1.5	-2.3	-2.9	2.1	-2.4	2.1	-2.5
Ever unenthusiastic/disinterested for a whole week	1.6	1.9	3.6	-0.3	0.8	-0.0	1.9	1.9	-1.3	1.5	-1.5	1.8
Qualifications: None of the above	0.1	0.2	0.5	-0.4	-0.0	-0.2	-0.2	0.5	-0.7	0.6	0.5	0.3
Financial difficulties in last 2 years	1.3	1.7	4.7	-0.8	-0.9	0.1	2.0	1.9	-1.0	0.8	-2.2	0.8
Mouth/teeth dental problems	0.7	1.0	3.6	0.5	-0.4	-0.4	-0.6	-1.8	0.2	-1.2	0.2	-1.9
Heart attack	0.3	0.4	1.2	0.6	1.0	0.5	-0.2	0.1	0.4	-1.1	0.6	-0.2
Allergy	0.5	1.2	4.5	2.1	0.5	-1.0	1.3	0.7	1.3	0.3	-1.1	0.3
Pain all over the body in last month	0.7	0.8	4.2	-0.8	-0.1	-0.3	-0.5	0.5	-2.1	1.1	-0.2	0.4
Diabetes (self-reported)	0.4	0.6	1.7	-0.8	-0.6	-0.4	-1.0	-1.3	-0.3	-0.6	0.7	-0.3
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	4.5	0.6	0.2	2.1	-0.7	0.2	0.6	0.3	0.9	0.2
Medication: Ramipril	1.4	1.8	5.0	2.2	0.8	1.0	-1.0	-0.7	1.6	-1.8	1.3	-0.7
Medication: Simvastatin	2.0	3.0	6.0	-1.6	-1.3	-0.3	-1.6	-2.3	-1.5	-2.5	1.1	-2.3
Fluid intelligence score	0.2	0.4	0.9	0.1	-0.0	0.9	-1.0	-0.5	-0.2	-0.7	0.8	-0.5
Illnesses of siblings	1.2	1.7	2.8	-1.3	-1.6	-1.4	1.1	0.6	-1.4	1.1	-1.7	1.2
Neuroticism score	0.2	0.5	2.3	0.2	-1.1	-0.4	-0.1	-0.4	-0.2	-0.6	-0.0	-1.5
Weight	0.3	1.6	4.2	-1.2	0.7	0.9	1.0	1.1	-1.4	1.6	-0.5	2.1
Impedance of arm (right)	0.2	0.8	3.3	0.6	-0.7	-1.8	-0.7	-0.2	0.8	-1.2	0.3	-0.9
Arm fat percentage (right)	0.3	1.1	2.8	-0.6	0.8	0.9	1.1	1.1	-0.3	1.2	-0.9	1.7
Trunk fat-free mass	0.2	1.0	2.2	-1.2	1.1	1.1	-0.3	-0.0	-1.2	1.1	0.6	1.5
Hip circumference	0.7	3.1	6.6	-1.3	0.9	0.3	1.8	2.1	-1.7	2.5	-1.5	2.6
Time employed in main current job	0.4	0.4	1.4	1.2	-0.0	-1.1	0.1	-0.4	0.8	-0.4	0.0	-0.3
Alcohol intake versus 10 years previously	0.4	0.6	1.9	0.4	1.4	1.3	-0.1	0.1	0.5	0.2	0.6	0.9
Father’s age at death	0.7	0.9	2.5	0.3	1.6	1.1	-0.8	-0.9	1.2	-0.3	1.1	-0.6
Worrier / anxious feelings	0.6	1.1	3.9	1.2	-0.5	0.3	-0.7	-1.0	1.0	-1.2	0.6	-2.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.9	0.4	-0.4	-0.3	-0.7	-0.2	0.2	-0.9	0.9	-1.4
Falls in the last year	1.0	1.4	7.4	-2.7	-0.3	0.2	0.3	0.5	-0.9	1.2	-0.9	1.3
Hair/balding pattern: Pattern 3	1.5	2.2	5.9	1.1	-2.3	-1.0	0.2	-1.3	1.1	-1.9	-0.1	-2.4
Number of live births	0.3	0.5	2.5	0.5	-0.3	1.6	-0.7	-0.1	0.9	-0.1	0.5	0.0
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	3.3	-0.6	0.8	-0.3	-0.1	1.3	-1.1	1.4	-0.4	1.8
Pulse rate	1.9	3.2	6.3	-0.9	-0.2	-2.0	2.4	1.8	-1.1	2.0	-2.5	2.0
Happiness	2.4	2.9	7.2	1.0	-1.8	2.7	-1.4	-0.7	0.8	-2.1	2.0	-1.8
Noisy workplace	1.5	1.9	4.5	-1.4	1.1	-1.0	0.9	2.1	-2.0	1.4	-1.1	0.5
Qualifications: A levels/AS levels or equivalent	0.5	1.1	5.2	-0.1	0.4	2.3	-0.8	0.2	1.6	-0.4	0.9	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	2.5	-0.5	1.6	-1.3	-0.4	0.1	-0.2	0.3	0.1	0.3
Mouth/teeth dental problems: Dentures	0.7	1.2	3.4	-0.7	0.4	-0.9	1.1	1.9	-0.9	1.0	-1.1	1.3
Asthma	1.8	3.5	6.7	-2.2	0.4	1.8	-2.6	-1.9	-1.6	-1.6	2.6	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.2	1.3	1.5	-0.1	-0.1	0.1	0.6	0.1	0.0	0.2
Medication: Cholesterol lowering	1.6	2.5	8.2	-0.7	-1.5	1.4	-1.3	-2.0	0.2	-2.9	1.4	-1.4
Depression (self-reported)	0.2	0.3	0.6	0.8	-0.2	-0.7	0.4	-0.4	-0.3	-0.7	-0.5	0.3
Medication: Lansoprazole	0.6	0.7	2.0	-0.1	0.4	0.1	1.1	0.5	1.2	0.6	-1.4	1.0
Prospective memory result	0.4	0.5	1.4	0.3	-0.4	0.5	-0.7	-0.8	0.4	-0.8	1.2	-0.7
Lung cancer (father)	0.4	0.5	1.5	1.2	-0.6	-0.2	0.7	0.6	-0.5	0.9	-0.7	0.3
Illnesses of mother	1.2	1.5	3.4	0.6	1.6	0.1	1.6	1.1	0.8	0.8	-1.3	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	4.6	-1.3	0.6	-0.3	0.0	1.5	-2.1	1.3	-0.5	1.3
Pulse wave Arterial Stiffness index	2.9	3.4	8.6	1.7	2.1	0.9	1.2	1.9	1.2	2.7	-0.8	2.9
Impedance of arm (left)	0.1	0.6	4.0	0.6	-0.6	-2.0	-0.1	0.6	0.3	-0.3	-0.4	-0.5
Arm fat mass (right)	0.3	1.4	3.9	-0.7	0.8	1.0	1.2	1.2	-0.8	1.6	-0.8	2.0
Trunk predicted mass	0.2	1.0	2.2	-1.3	1.1	1.1	-0.4	-0.0	-1.2	1.1	0.6	1.5
Standing height	0.1	0.6	1.2	-0.7	0.3	-1.0	-1.1	-0.1	-0.9	0.2	1.1	0.5
Length of working week for main job	0.4	0.4	1.9	-0.0	0.3	-0.7	-0.4	-0.3	-0.3	-1.0	0.4	-1.4
Exposure to tobacco smoke at home	0.3	0.3	0.8	0.9	0.3	-0.5	0.8	0.2	0.5	-0.1	-0.3	0.6
Breastfed as a baby	1.4	1.8	3.9	1.9	1.8	1.6	0.7	-0.2	2.0	0.2	-0.3	1.3
Tense / ‘highly strung’	0.4	0.6	1.7	-0.4	-0.2	-1.3	0.9	0.4	-1.2	0.2	-0.9	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.8	-0.2	0.9	0.7	0.0	0.6	0.2	0.6	-0.5	0.5
Hair/balding pattern: Pattern 4	0.5	1.3	3.8	-0.0	1.9	1.0	-1.9	-0.0	0.2	-0.5	1.6	-0.4
Birth weight of first child	0.4	0.7	2.2	1.4	0.8	0.1	-0.1	-0.5	1.5	-0.8	0.4	-0.6
Peak expiratory flow (PEF)	1.7	4.0	10.0	-1.6	2.0	-0.2	1.0	2.1	-2.1	2.6	-1.7	3.2
Pulse wave reflection index	1.5	1.9	3.9	2.0	1.9	1.0	0.3	1.1	0.9	1.8	-0.2	1.6
Ever highly irritable/argumentative for 2 days	1.3	1.6	5.4	-0.4	0.5	0.5	0.8	1.3	-1.2	2.3	-0.8	2.0
Loud music exposure frequency	0.3	0.3	1.5	-1.2	0.4	0.2	0.2	0.3	-0.9	-0.1	0.2	0.6
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.9	0.2	1.4	-0.2	1.3	0.2	0.5	-0.6	-0.4	-0.7
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.4	-0.8	-1.6	1.4	0.2	0.5	-0.3	0.6	-0.2	-0.2
Blood clot in the leg (DVT)	0.4	0.5	1.6	-0.6	0.6	0.4	0.5	0.6	-1.0	0.7	-0.6	1.3
Medication: Paracetamol	0.3	0.5	1.5	-1.0	-0.7	-0.3	1.2	-0.1	-0.2	-0.9	-1.0	0.1
Headache pain in last month	1.0	1.6	3.4	0.9	-1.6	-1.8	1.3	1.3	0.3	1.2	-1.8	0.3
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.1	0.6	0.1	-1.4	-0.3	0.2	-0.2	1.4	-0.2	-0.2
Glaucoma (self-reported)	1.4	1.6	3.4	-1.1	-1.4	0.3	-1.1	-1.8	-0.6	-1.6	1.4	-1.5
Gout (self-reported)	0.5	0.7	1.5	-1.2	0.4	0.2	-1.2	-1.1	-0.0	-0.9	0.9	-0.9
Hypothyroidism/myxoedema (self-reported)	1.8	3.6	7.1	-1.6	0.2	-1.1	2.7	2.2	-1.5	1.8	-2.5	2.2
Medication: Amlodipine	0.1	0.1	0.6	0.6	0.5	-0.1	0.1	-0.1	0.8	0.3	0.2	-0.2
Medication: Ventolin 100micrograms inhaler	1.9	2.4	6.6	-0.6	1.6	2.6	-2.1	-1.5	0.7	-1.0	2.1	0.1
Birth weight	0.8	1.7	3.6	-1.7	-1.9	0.1	-1.0	-1.0	-1.4	-1.1	0.7	-1.9
Chronic bronchitis/emphysema (mother)	2.3	2.7	6.7	0.3	-1.5	1.2	-1.7	-1.4	1.4	-1.9	1.9	-2.6
High blood pressure (siblings)	0.3	0.4	1.3	0.8	1.0	1.2	0.3	0.2	0.6	-0.1	0.1	0.1
Forced vital capacity (FVC), Best measure	0.3	1.0	3.1	-1.1	0.3	0.5	-1.8	0.0	-1.6	0.0	1.2	0.3
Body fat percentage	0.4	1.5	3.0	-0.9	-0.4	0.2	1.7	1.5	-0.9	1.3	-1.4	1.5
Leg fat percentage (right)	0.9	3.2	7.3	-1.6	-1.1	-0.7	2.7	1.7	-1.6	1.7	-2.5	1.6
Arm fat-free mass (right)	0.2	1.0	2.4	-0.8	1.0	1.2	0.3	0.6	-1.2	1.3	0.1	1.6
Exposure to tobacco smoke outside home	0.5	0.6	2.5	1.1	0.4	0.1	-0.4	-0.6	1.6	-0.1	1.0	-0.1
Comparative body size at age 10	0.7	1.9	6.8	-2.6	0.0	0.8	0.4	1.6	-1.7	1.4	-0.2	1.3
Number of full brothers	0.8	1.0	5.1	0.1	-2.2	0.1	-0.2	-0.9	-0.7	-0.8	0.2	-1.4
Worry too long after embarrassment	0.7	1.2	5.4	-0.2	-2.3	-1.6	-0.2	0.6	-0.9	0.6	-0.3	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	1.1	-0.5	0.0	-1.1	-0.3	0.1	-0.1	0.5	-0.1	-0.2
Wheeze or whistling in the chest in last year	0.5	1.0	5.1	-1.1	2.3	-0.1	-0.8	0.2	-0.9	-0.1	0.9	0.2
Number of children fathered	2.0	2.3	6.9	-2.6	0.1	1.1	0.3	0.8	-2.6	1.3	-0.9	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.8	-0.5	0.5	0.4	-0.8	-0.2	-0.1	-0.1	0.9	-0.2
Age at first live birth	0.3	0.5	1.8	-0.2	0.7	-0.7	0.2	-1.3	0.1	-1.1	0.0	0.3
Pulse wave peak to peak time	2.8	3.3	7.8	-1.7	-2.0	-1.0	-1.3	-1.8	-1.2	-2.7	0.9	-2.8
Health satisfaction	0.2	0.2	0.7	0.3	-0.7	0.8	-0.5	-0.2	-0.0	0.4	0.3	-0.3
Shortness of breath walking on level ground	0.4	0.5	2.0	0.6	-0.1	-1.4	0.2	0.6	-0.2	0.5	-0.5	-1.1
Qualifications: College or University degree	0.4	1.4	2.8	0.9	1.6	0.9	-1.7	-1.0	1.2	-0.8	1.5	0.3
Eye problems/disorders: None of the above	1.1	1.3	3.0	0.5	-0.2	0.4	1.7	1.2	0.4	1.2	-1.6	1.7
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.6	0.7	0.8	1.0	-0.2	0.2	1.3	0.6	0.4	0.9
Emphysema/chronic bronchitis	1.4	1.5	4.8	0.8	-1.6	-0.3	-1.2	-1.1	0.9	-1.2	0.8	-2.2
Medication for pain relief, constipation, heartburn	0.2	0.3	1.2	0.5	0.5	-0.4	-0.6	-0.1	1.1	0.6	0.5	-0.2
Neck or shoulder pain in last month	0.9	1.3	4.3	1.3	0.5	-0.1	2.1	0.8	1.0	0.3	-1.8	0.6
Medication: Blood pressure	0.5	0.8	3.1	0.3	1.1	0.3	1.8	1.1	0.6	-0.1	-0.6	1.0
Angina (self-reported)	1.0	1.4	3.6	-0.5	-0.8	1.0	-1.4	-1.3	-0.7	-1.9	1.3	-1.0
Migraine (self-reported)	0.9	1.1	2.1	-0.2	-1.1	-1.2	-1.1	-1.1	-1.0	-1.4	0.4	-1.3
Medication: Ibuprofen	0.4	0.5	2.8	0.7	1.7	-0.2	-0.5	0.1	0.3	0.3	0.5	0.5
Medication: Allopurinol	0.7	0.9	2.0	-1.4	-0.7	-1.3	1.0	0.3	-0.9	0.5	-1.2	-0.0
Medication: Omeprazole	0.9	1.1	3.1	-1.8	-1.4	-0.6	0.5	0.6	-1.7	0.2	-0.9	-0.1
Medication: Seretide 50 evohaler	0.6	0.7	1.6	-1.1	0.7	0.8	-1.2	-0.9	-0.3	-0.3	0.9	-0.0
Mean time to correctly identify matches	0.0	0.1	0.4	0.2	0.2	-0.0	-0.1	0.3	0.0	0.6	0.1	0.0
Heart disease (mother)	0.4	0.4	1.3	0.4	-1.2	0.9	-0.4	1.0	0.3	0.6	-0.0	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.8	0.9	0.9	0.3	0.1	-0.2	1.3	-0.7	-0.1	0.5
Whole body fat mass	0.3	1.3	2.3	-1.0	-0.2	0.5	1.5	1.2	-1.1	1.3	-1.1	1.5
Leg fat mass (right)	0.5	2.0	4.2	-1.3	-0.0	-0.0	2.0	1.4	-1.5	1.6	-1.6	1.8
Arm predicted mass (right)	0.2	1.2	3.0	-0.8	1.0	1.1	0.3	0.7	-1.4	1.5	0.0	1.7
Pulse rate, automated reading	0.9	2.7	5.7	-1.5	-1.8	-0.9	2.4	1.2	-1.2	1.7	-2.3	1.3
Alcohol intake frequency.	0.2	0.4	0.6	0.5	0.6	0.6	-0.4	-0.7	0.6	-0.8	0.8	-0.2
Comparative height size at age 10	0.4	2.0	4.5	-1.9	-1.1	-1.4	-0.2	1.1	-2.1	1.9	-0.2	1.5
Number of full sisters	1.3	1.6	4.2	-0.1	-0.6	-1.9	-1.2	-1.3	0.0	-1.3	1.0	-2.0
Suffer from ‘nerves’	0.6	0.9	3.0	-1.7	-1.1	-0.5	-0.0	-0.1	-1.7	0.2	-0.1	-0.8
Overall health rating	0.4	0.8	2.6	0.4	-0.4	-1.0	-0.3	-0.4	0.2	-1.6	0.7	-1.5
Chest pain or discomfort	1.6	2.3	5.1	1.2	0.6	1.6	-2.3	-1.3	1.6	-1.2	2.2	-0.9
Had major operations	2.2	2.6	6.5	2.5	1.3	1.7	-0.7	-1.0	2.5	-1.6	1.5	-0.3
Age at last live birth	0.9	1.3	3.3	0.7	0.0	1.4	-0.9	-1.5	1.3	-1.8	0.9	-0.7
Family relationship satisfaction	1.8	2.2	6.7	2.6	0.5	1.3	-1.2	-0.5	1.4	-1.7	1.8	-1.1
Leg pain on walking	0.6	0.8	5.2	-0.1	0.7	2.3	0.1	0.4	0.8	-0.1	0.5	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	5.0	-1.0	-2.2	0.4	-0.5	-0.5	-0.7	-0.3	0.6	-0.4
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.6	0.4	-0.7	-0.1	0.3	-0.3	0.1	-0.7	-0.2	-0.4
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	3.2	1.8	-1.2	0.4	-0.7	-0.9	1.4	-0.9	0.6	-1.5
Medication: Aspirin	0.3	0.4	0.9	0.2	-0.5	1.0	-0.9	0.1	-0.8	-0.1	0.9	0.2
Supplements: Vitamin C	0.4	0.5	1.2	0.2	1.1	-0.1	0.9	-0.5	0.4	0.5	-1.1	0.6
Knee pain experienced in last month	0.3	0.4	2.6	-0.2	-0.7	1.6	-0.2	0.3	-0.2	-0.2	0.2	-0.3
Hypertension (Self-reported)	0.4	1.2	2.6	-0.9	0.7	0.6	1.1	1.6	-0.9	1.4	-0.6	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	6.8	0.9	-0.3	-0.9	2.6	0.7	0.7	-0.0	-2.4	0.7
Illnesses of father: Heart disease	1.1	1.5	7.3	-2.0	-0.1	-0.5	-1.1	-0.2	-2.7	-0.0	1.0	0.0
Illnesses of siblings: Diabetes	0.1	0.1	0.2	0.1	0.4	-0.3	-0.4	-0.5	0.2	0.1	0.3	0.2
Smoking status: Previous	0.7	1.1	2.5	-0.2	-1.1	1.3	-0.4	-1.4	0.4	-1.6	1.3	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	1.6	1.3	0.7	0.2	0.3	0.4	1.0	0.2	-0.5	1.1
Whole body fat-free mass	0.2	1.1	2.2	-1.2	1.2	1.5	-0.5	-0.0	-1.1	0.9	0.8	1.4
Leg fat-free mass (right)	0.2	1.3	3.7	-0.8	1.6	1.9	-0.6	0.2	-0.6	0.7	1.1	1.4
Arm fat percentage (left)	0.4	1.5	3.3	-0.7	0.7	0.9	1.5	1.5	-0.6	1.6	-1.2	1.8
Average weekly red wine intake	0.7	1.0	2.2	0.9	-1.5	0.1	-1.3	-1.3	1.3	-0.4	0.7	-0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	-0.8	-0.2	-0.3	0.6	-0.8	-0.1	-0.3	0.2	0.3
Mood swings	0.3	0.5	1.2	-0.7	-0.5	-0.9	0.4	0.5	-1.1	1.0	-0.7	0.3
Loneliness, isolation	0.5	0.7	3.7	-0.7	0.7	-1.9	0.4	0.4	-0.4	0.9	-0.5	0.3
Long-standing illness, disability or infirmity	1.5	2.2	5.7	0.7	0.6	1.4	-1.9	-1.9	0.7	-2.4	1.6	-1.2
Ever had bowel cancer screening	1.4	1.6	4.2	-1.4	-2.1	-1.7	1.1	-0.0	-0.8	1.0	-1.4	0.9
Diabetes diagnosed by doctor	0.7	1.2	3.0	-1.0	-0.5	0.2	-1.7	-1.5	-1.0	-0.8	1.5	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	2.7	2.9	5.5	-0.0	-1.7	1.2	-1.9	-2.4	0.4	-2.0	1.8	-2.2
Friendships satisfaction	2.3	2.8	4.8	1.9	-2.2	0.7	-1.2	-1.1	1.7	-1.9	1.7	-2.1
Qualifications: nursing, teaching	0.3	0.5	1.9	1.4	-0.0	1.1	-0.3	-0.0	0.6	-0.5	0.3	0.7
Commuting to job workplace: Walk	0.6	0.6	1.7	-1.1	1.3	-0.4	0.1	-0.1	-1.0	0.6	-0.1	0.9
Eye problems/disorders: Cataract	0.3	0.4	0.8	0.9	0.9	0.2	-0.7	0.2	0.5	-0.4	0.6	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.0	0.6	0.3	-1.3	1.4	0.4	0.4	0.6	-1.0	1.3
Medication for cholesterol	0.5	0.8	3.9	0.9	-0.2	1.3	0.4	-0.2	2.0	-0.5	-0.1	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.1	-0.2	0.1	-1.1	0.0	-0.7	-1.0	0.6	-0.4	0.6
Back pain experienced in last month	0.7	1.0	3.3	-1.4	-0.8	0.4	0.1	-0.5	-1.8	-1.3	-0.3	-1.0
Mineral and other dietary supplements	1.0	1.3	4.1	-0.8	0.8	1.7	-1.4	-0.6	-0.7	-0.6	2.0	-0.8
Breast cancer (self-reported)	5.1	6.0	11.8	-2.0	-1.6	-2.3	2.7	2.5	-2.8	2.6	-3.4	1.7
Asthma (self-reported)	1.5	3.1	5.4	-2.3	0.5	1.5	-2.3	-1.9	-1.8	-1.4	2.3	-0.6
Osteoporosis (self-reported)	1.5	1.8	7.9	-0.5	-0.4	-0.1	-1.5	-1.5	-0.3	-1.5	1.2	-2.8
Osteoarthritis (self-reported)	2.4	3.1	6.5	0.8	-0.3	2.2	-2.2	-1.9	1.3	-2.5	1.3	-1.9
Medication: Aspirin	0.3	0.4	1.1	0.0	-0.5	0.7	-0.9	0.0	-0.8	-0.2	1.1	0.2
Medication: Gliclazide	0.7	0.8	2.0	-1.4	-1.0	0.5	1.2	0.1	-1.4	-0.1	-0.9	-0.2
Illnesses of father: None of the above (group 1)	0.6	0.8	1.7	1.0	-0.3	-0.9	1.0	-0.0	1.1	-0.5	-1.3	-0.9
Smoking status: Current	1.7	2.7	7.8	0.3	2.1	0.6	1.5	2.0	0.6	1.9	-1.3	2.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.7	-0.8	0.8	0.4	-0.2	0.0	-0.3	0.6	-0.0	0.7
Whole body water mass	0.2	1.1	2.6	-1.0	1.2	1.6	-0.4	0.1	-1.0	0.9	0.7	1.4
Leg predicted mass (right)	0.2	1.3	3.6	-0.9	1.6	1.9	-0.6	0.2	-0.7	0.7	1.1	1.4
Arm fat mass (left)	0.4	1.7	4.2	-0.9	0.7	0.9	1.3	1.4	-0.9	1.8	-1.0	2.0
Number of self-reported non-cancer illnesses	1.0	1.7	3.0	-1.7	-1.4	1.2	-1.7	-0.7	-1.2	-1.2	1.1	-1.1
Average weekly champagne plus white wine intake	0.3	0.5	1.0	-1.0	0.9	0.9	0.1	-0.7	-0.6	-0.1	0.2	0.8
Miserableness	0.3	0.5	1.1	-0.7	0.3	-0.9	0.0	0.8	-1.1	0.8	-0.3	0.7
Guilty feelings	0.7	1.0	3.3	1.2	-1.1	-1.8	0.7	0.1	0.4	-0.9	-0.8	-1.1
Wears glasses or contact lenses	0.6	0.7	1.8	-0.7	-0.6	0.8	0.2	1.3	-0.5	1.0	-1.0	0.8
Ever taken oral contraceptive pill	0.3	0.3	0.7	-0.6	-0.7	0.8	-0.4	-0.0	-0.3	-0.8	0.7	0.2
Hearing aid user	1.2	1.3	3.6	-0.2	-0.9	1.8	-1.5	-0.5	0.2	-0.8	1.0	-1.9
Mother’s age at death	0.4	0.5	2.5	0.2	-0.7	-1.6	0.6	0.5	-0.3	0.2	-0.6	-0.6
Financial situation satisfaction	0.2	0.2	0.7	-0.2	0.1	0.6	0.4	-0.3	0.4	-0.8	-0.0	-0.7
Tinnitus: Yes, now most or all of the time	1.5	1.7	7.2	-0.2	-1.0	-0.6	2.1	1.1	-0.5	0.8	-2.7	0.8
Commuting to job workplace: Public transport	0.3	0.4	1.0	-0.8	0.3	0.7	-1.0	-0.3	0.6	0.2	0.9	0.0
Eye problems/disorders: Glaucoma	2.7	3.2	6.1	-0.9	-1.3	1.3	-1.7	-2.5	-0.0	-2.2	2.1	-2.5
Medication: Blood pressure	0.3	0.5	2.3	-0.6	0.5	0.4	-0.8	0.2	-1.5	0.7	0.8	0.0
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.3	-0.8	-1.5	0.7	-0.3	0.0	-0.8	-0.4	0.1	-0.7
Supplements: Fish oil (including cod liver oil)	2.7	3.5	8.9	0.5	-0.5	-2.7	2.5	1.5	-0.1	1.9	-3.0	1.7
High cholesterol (Self-reported)	1.7	3.1	7.9	-1.3	-2.2	0.0	-1.0	-2.2	-0.3	-2.8	0.8	-2.5
Medication: Bendroflumethiazide	0.8	1.2	2.1	1.1	0.2	0.4	-0.9	-1.4	1.3	-1.4	1.2	-1.1
Medication: Paracetamol	0.2	0.2	0.5	-0.4	0.2	0.6	0.7	0.1	0.7	-0.2	-0.6	0.5
Medication: Lisinopril	1.1	1.4	3.6	0.5	-1.1	-1.1	1.9	1.5	0.6	0.9	-1.6	0.5
Medication: Atorvastatin	0.8	1.0	3.2	-1.8	-0.1	1.7	-0.9	-0.5	0.5	-0.9	0.9	-0.3
Illnesses of father: High blood pressure	0.5	0.6	2.1	-0.6	-0.2	-0.2	-0.2	0.7	-0.7	1.2	0.3	1.5
Alcohol drinker status: Never	0.2	0.2	0.6	0.8	-0.5	-0.7	0.3	-0.2	0.3	0.1	-0.3	0.3
Ever smoked	0.6	1.1	6.6	-0.6	0.8	2.6	-0.1	0.2	0.5	-0.2	0.9	1.0
Basal metabolic rate	0.2	1.1	2.8	-1.1	1.1	1.4	-0.1	0.4	-1.2	1.2	0.4	1.7
Leg fat percentage (left)	0.7	2.7	6.8	-1.1	-0.6	-0.6	2.6	1.6	-1.1	1.8	-2.3	1.8
Arm fat-free mass (left)	0.2	0.8	2.1	-0.7	0.9	1.3	-0.2	0.0	-0.9	1.0	0.5	1.4
Number of operations (self-reported)	0.3	0.5	1.9	1.4	0.4	-0.5	-0.7	-0.3	0.9	-0.5	0.6	-0.3
Average weekly beer plus cider intake	0.2	0.4	1.0	-1.0	0.4	0.4	-0.4	0.0	0.2	-0.8	0.9	-0.5
Irritability	0.3	0.6	2.8	-0.8	1.1	1.7	0.0	0.1	-0.6	-0.1	0.2	0.4
Risk taking	0.8	1.2	3.5	-0.9	0.1	0.0	0.9	1.3	-1.9	1.3	-1.1	1.0
Ever had prostate specific antigen (PSA) test	2.1	2.5	6.2	-0.7	-0.4	-2.2	1.7	2.5	-1.3	1.7	-1.8	0.4
Fractured/broken bones in last 5 years	0.2	0.2	0.6	-0.4	-0.3	-0.1	0.3	0.4	0.3	0.5	-0.6	0.8
Age started oral contraceptive pill	0.2	0.2	0.8	-0.5	0.2	0.1	0.9	0.1	-0.5	0.4	-0.7	0.3
Diastolic blood pressure, automated reading	1.2	3.8	9.7	0.5	1.6	1.4	2.0	1.8	-0.2	3.0	-1.9	3.1
Ever depressed for a whole week	0.1	0.1	0.3	0.5	-0.3	0.4	0.4	-0.4	0.1	-0.2	-0.4	0.4
Unable to work because of sickness or disability	0.4	0.5	2.0	-0.1	0.6	0.7	0.3	-0.1	-1.1	0.7	-0.4	1.4
Commuting to job workplace: Cycle	0.4	0.5	1.8	0.6	0.4	-1.4	1.0	0.4	0.0	-0.0	-0.6	0.7
Myopia	0.2	0.3	0.9	0.6	-1.0	-0.5	-0.3	-0.1	0.3	0.8	-0.0	0.5
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.6	0.4	-0.4	-0.8	-0.3	-0.7	0.4	-0.1	-0.3	-0.5
Cholesterol lowering medication	0.6	0.9	2.8	-1.7	-0.7	-0.1	-1.3	-0.6	-1.3	-0.2	0.5	-0.9
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	3.1	-1.8	-0.8	-1.0	1.5	1.3	-1.4	0.9	-1.7	0.8
Pain experienced in last month	0.7	1.2	2.8	0.8	1.2	1.7	-0.8	-0.5	1.3	0.5	1.3	1.1
Supplements: Calcium	0.3	0.4	1.0	0.4	0.1	-0.5	0.3	0.9	-0.3	0.6	-1.0	-0.7
Basal cell carcinoma (self-reported)	0.4	0.4	1.7	0.7	-1.3	0.2	-0.1	0.3	1.0	-0.2	0.1	-0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.3	1.1	0.4	0.9	0.4	-0.3	0.0	0.3	-1.0	0.6	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.8	-0.9	0.4	0.3	0.6	0.8	-1.2	0.6	-0.7	1.3
Heart disease (siblings)	0.8	1.0	4.7	-1.7	0.1	1.0	-0.2	-0.1	-2.2	0.5	0.2	-0.2
Alcohol drinker status: Previous	1.3	1.4	3.0	0.4	0.7	1.7	-1.1	-1.7	0.7	-1.6	1.3	-0.9
Pack years of smoking	0.6	0.8	1.8	0.3	-0.6	-0.9	-1.2	-1.1	0.6	-1.2	1.3	-0.5
Impedance of whole body	0.3	1.4	8.7	0.7	-1.1	-2.9	0.1	0.3	0.4	-0.7	-0.6	-0.8
Leg fat mass (left)	0.5	2.1	4.4	-1.1	0.2	-0.1	2.1	1.4	-1.2	1.7	-1.6	2.0
Arm predicted mass (left)	0.2	0.8	2.1	-0.6	1.1	1.4	-0.2	0.2	-0.9	0.9	0.5	1.4