[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr12:27,172,878-28,607,631

Best TWAS P=2.46e-12 · Best GWAS P=3.61e-11 conditioned to 0.0495

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Esophagus Mucosa	MRPS35	0.18	0.00	enet	20	0.01	6.6e-02	-3.6	5.6	2.2e-08	-0.31	0.07	0.36	FALSE
2	YFS	Blood	MRPS35	0.04	0.02	enet	8	0.03	3.3e-09	-3.7	6.3	2.7e-10	-0.79	0.06	0.94	FALSE
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC100133893	0.04	0.08	blup	33	0.10	3.6e-19	-6.0	-6.7	2.9e-11	0.79	0.02	0.98	FALSE
4	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC100133893	0.07	0.03	blup	33	0.07	7.1e-05	-5.8	-6.0	2.6e-09	0.72	0.02	0.94	FALSE
5	The Cancer Genome Atlas	Glioblastoma Multiforme	LOC100133893	0.12	0.05	lasso	4	0.07	3.5e-03	-6.0	-6.5	5.6e-11	0.82	0.02	0.55	FALSE
6	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LOC100133893	0.07	0.10	blup	33	0.11	1.2e-12	-6.4	-7.0	2.5e-12	0.76	0.01	0.99	TRUE
7	The Cancer Genome Atlas	Lung Adenocarcinoma	LOC100133893	0.09	0.19	lasso	7	0.18	2.8e-20	-6.4	-6.7	3.0e-11	0.75	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LOC100133893	0.03	0.03	blup	33	0.03	5.4e-04	-4.9	-6.2	5.4e-10	0.68	0.04	0.95	FALSE
9	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LOC100133893	0.04	0.01	blup	33	0.03	2.1e-03	-5.0	-5.7	1.3e-08	0.70	0.02	0.64	FALSE
10	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LOC100133893	0.06	0.04	blup	33	0.04	1.0e-02	-6.0	-6.8	9.7e-12	0.77	0.01	0.75	FALSE
11	The Cancer Genome Atlas	Stomach Adenocarcinoma	KLHDC5	0.06	0.04	blup	55	0.02	6.3e-03	-5.8	6.6	4.3e-11	-0.58	0.02	0.94	FALSE
12	The Cancer Genome Atlas	Stomach Adenocarcinoma	LOC100133893	0.08	0.09	lasso	2	0.08	2.8e-06	-5.0	-5.3	1.3e-07	0.47	0.15	0.80	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	LOC100133893	0.06	0.06	lasso	4	0.06	2.1e-06	-6.4	-6.6	4.9e-11	0.80	0.01	0.99	FALSE