Best TWAS P=1.23e-08 · Best GWAS P=5.32e-06 conditioned to 0.664
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | GNPTAB | 0.08 | 0.02 | enet | 13 | 0.03 | 8.2e-04 | -4.0 | 5.4 | 6.6e-08 | -0.70 | 0.02 | 0.52 | FALSE |
| 2 | GTEx | Artery Tibial | GNPTAB | 0.25 | 0.15 | lasso | 5 | 0.21 | 4.1e-16 | -4.3 | 5.3 | 1.2e-07 | -0.83 | 0.01 | 0.94 | FALSE |
| 3 | GTEx | Prostate | DRAM1 | 0.57 | 0.08 | lasso | 20 | 0.00 | 2.7e-01 | 0.9 | -5.7 | 1.2e-08 | 0.19 | 0.01 | 0.04 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GNPTAB | 0.04 | 0.03 | blup | 62 | 0.04 | 9.7e-05 | -4.5 | 5.3 | 9.6e-08 | -0.91 | 0.01 | 0.81 | TRUE |