TWAS hub - GNPTAB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1010	0.0360	2.2e-03	0.035	0.026	0.029	0.030	0.038	3.6e-05	3.4e-04	1.7e-04	1.4e-04	1.7e-05
2	GTEx	Adipose Subcutaneous	0.0780	0.0320	6.5e-03	0.021	NA	0.034	NA	0.021	7.2e-03	NA	8.2e-04	NA	6.9e-03
3	GTEx	Artery Aorta	0.2580	0.0740	2.9e-04	0.108	NA	0.026	NA	0.087	1.5e-06	NA	1.3e-02	NA	1.6e-05
4	GTEx	Artery Tibial	0.2548	0.0473	4.3e-10	0.151	NA	0.200	NA	0.207	7.2e-12	NA	1.3e-15	NA	4.1e-16
5	GTEx	Colon Sigmoid	0.2880	0.0780	7.7e-04	0.203	NA	0.092	NA	0.138	1.0e-07	NA	3.9e-04	NA	1.4e-05
6	GTEx	Colon Transverse	0.2370	0.0660	1.1e-04	0.184	NA	0.123	NA	0.188	4.0e-09	NA	2.0e-06	NA	2.6e-09
7	GTEx	Esophagus Mucosa	0.2180	0.0600	3.7e-04	-0.004	NA	0.003	NA	0.000	8.0e-01	NA	2.0e-01	NA	3.2e-01
8	GTEx	Esophagus Muscularis	0.2680	0.0570	4.5e-08	0.219	NA	0.196	NA	0.196	1.9e-13	NA	4.8e-12	NA	4.7e-12
9	GTEx	Thyroid	0.0920	0.0350	5.3e-04	0.026	NA	0.017	NA	0.035	3.9e-03	NA	1.7e-02	NA	1.0e-03
10	YFS	Blood	0.0340	0.0122	3.7e-04	0.017	0.010	0.016	0.011	0.017	2.3e-06	2.0e-04	5.3e-06	8.9e-05	2.5e-06
11	TCGA	Breast Invasive Carcinoma	0.0415	0.0197	3.7e-04	0.004	0.016	0.017	NA	0.011	4.7e-02	2.3e-04	1.6e-04	NA	2.2e-03
12	TCGA	Esophageal Carcinoma	0.1320	0.0670	4.7e-03	0.002	0.021	0.019	NA	0.005	2.7e-01	6.9e-02	7.9e-02	NA	2.1e-01
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0528	0.0269	1.7e-03	-0.001	0.011	0.006	NA	0.000	3.9e-01	1.9e-02	6.3e-02	NA	2.8e-01
14	TCGA	Brain Lower Grade Glioma	0.0868	0.0344	1.1e-05	0.043	0.046	0.044	NA	0.044	1.2e-05	5.2e-06	8.0e-06	NA	7.9e-06
15	TCGA	Lung Adenocarcinoma	0.0641	0.0314	8.8e-04	0.018	0.036	0.032	NA	0.017	3.2e-03	4.0e-05	1.1e-04	NA	3.9e-03
16	TCGA	Lung Squamous Cell Carcinoma	0.0607	0.0305	2.2e-03	0.010	0.021	0.017	NA	0.005	2.1e-02	1.6e-03	4.5e-03	NA	7.6e-02
17	TCGA	Prostate Adenocarcinoma	0.0427	0.0229	6.7e-04	0.026	0.036	0.024	NA	0.026	8.7e-04	9.7e-05	1.4e-03	NA	8.6e-04
18	TCGA	Rectum Adenocarcinoma	0.3190	0.1390	6.4e-03	-0.001	0.116	0.137	NA	0.089	3.5e-01	1.2e-03	4.3e-04	NA	4.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Chronic bronchitis/emphysema (mother)	6.0	7.0	15.3	-3.4	-3.4	-3.8	-3.6	-3.5	-1.9	-3.9	-2.2	0.0	-2.5	-2.3	-0.8	-1.8	-1.6	-2.1	-2.7	-2.8	-1.4
Hearing aid user	4.7	5.3	10.9	-1.7	-2.8	-3.3	-2.7	-3.1	-2.7	-0.7	-2.8	2.5	-3.2	-1.6	-2.5	-1.4	-1.5	-0.0	-1.9	-2.5	-0.9
Diabetes (father)	4.3	5.3	11.2	-1.9	-2.7	-3.0	-2.9	-3.3	-2.7	-1.9	-2.7	1.4	-2.5	-2.0	-1.9	-1.5	-1.6	-1.1	-2.6	-2.7	-0.9
Family relationship satisfaction	4.2	5.2	9.2	2.2	2.5	3.0	3.0	2.7	2.2	2.9	2.3	-0.3	2.4	2.2	2.7	1.1	1.1	1.6	2.6	2.7	0.7
Number of full sisters	3.7	4.5	13.9	0.9	3.7	2.3	2.9	2.3	2.6	1.1	2.4	1.0	1.8	1.5	3.2	-0.4	-0.2	2.2	1.9	2.8	-0.2
Alcohol usually taken with meals	3.6	5.8	14.7	-2.3	-1.1	-2.2	-2.4	-2.2	-2.8	-1.4	-3.0	1.2	-1.8	-3.4	-3.8	-1.4	-1.5	-2.8	-2.9	-3.0	-2.0
Alzheimer’s Disease (in mother)	3.1	3.7	6.8	1.7	2.4	2.5	2.6	2.4	1.8	2.6	1.8	-0.5	2.3	2.1	1.6	1.5	1.4	0.9	1.9	2.0	0.6
Ever had stillbirth, spontaneous miscarriage or termination	3.0	3.2	5.0	1.7	1.9	1.9	2.0	2.0	1.8	1.4	1.9	-1.3	1.7	1.6	1.7	2.0	1.9	1.1	2.2	1.6	1.8
Lung FEV1/FVC ratio	2.9	14.5	29.2	3.0	5.4	4.2	5.3	4.6	4.6	3.4	4.6	-2.1	2.8	3.3	4.5	0.9	1.1	3.3	3.7	5.3	1.9
Migraine (self-reported)	2.8	3.5	7.3	1.7	1.7	2.5	2.4	2.4	2.1	0.6	2.3	-2.0	1.9	1.6	2.0	0.6	0.5	1.3	1.9	2.7	1.4
Hypothyroidism/myxoedema (self-reported)	2.7	5.2	10.1	2.7	2.1	3.2	3.0	2.8	2.2	1.5	2.4	-0.9	2.9	2.5	1.6	1.8	1.8	1.5	2.7	2.6	1.3
Average weekly red wine intake	2.7	4.0	8.3	-2.1	-1.6	-2.0	-2.2	-2.0	-1.9	-1.2	-2.1	-0.1	-2.1	-2.6	-2.9	-1.0	-1.3	-2.4	-2.7	-2.3	-1.3
Forced vital capacity (FVC)	2.6	10.2	25.6	-1.2	-4.7	-3.0	-4.2	-3.0	-3.9	-4.1	-3.9	2.0	-3.7	-1.7	-4.2	0.9	0.5	-2.5	-2.2	-5.1	-0.9
Illness, injury, bereavement, stress in last 2 years	2.6	3.2	7.8	-1.3	-1.3	-1.6	-1.4	-2.1	-2.2	-0.0	-2.2	1.1	-2.3	-1.8	-1.5	-2.5	-2.8	-0.1	-1.6	-1.0	-2.2
Ever taken oral contraceptive pill	2.6	2.9	8.5	-2.4	-0.8	-2.9	-2.0	-2.7	-1.2	-1.4	-1.4	0.6	-2.3	-1.4	-0.4	-2.0	-2.0	-0.1	-1.9	-1.4	-0.7
Bipolar Disorder (2011)	2.5	2.4	5.7	2.4	2.1	1.4	2.1	1.5	1.7	0.6	1.8	0.5	0.1	2.4	0.8	0.5	0.6	2.0	1.0	1.8	1.6
Forced vital capacity (FVC), Best measure	2.3	8.4	21.2	-0.6	-4.6	-2.8	-3.9	-2.7	-3.0	-3.9	-3.1	1.5	-4.0	-0.8	-3.8	1.4	1.1	-1.8	-1.8	-4.6	0.6
Shortness of breath walking on level ground	2.3	2.7	7.8	-1.6	-0.1	-1.8	-0.8	-1.9	-1.2	-0.5	-1.1	2.4	-2.2	-1.3	0.0	-2.8	-2.7	0.5	-1.7	-0.7	-2.1
Average weekly spirits intake	2.2	2.7	5.7	-1.7	-1.9	-1.8	-2.2	-1.6	-1.4	-1.4	-1.7	-0.8	-2.1	-1.5	-1.7	-0.3	-0.5	-2.3	-2.4	-1.9	-0.2
Diabetes (mother)	2.1	2.6	5.4	-1.2	-1.2	-2.1	-1.5	-2.0	-1.9	-0.7	-1.8	1.7	-1.5	-1.0	-1.4	-2.1	-1.9	-0.2	-2.3	-1.6	-1.3
Heart disease (mother)	2.1	2.6	4.8	-1.9	-1.4	-2.0	-1.6	-2.1	-1.4	-1.2	-1.6	1.3	-2.1	-1.7	-0.9	-2.2	-2.0	-0.2	-1.7	-1.1	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.5	11.8	-0.8	-3.4	-2.2	-2.7	-2.2	-2.1	-2.6	-2.3	1.4	-2.6	-0.9	-2.7	0.2	0.3	-1.6	-1.9	-3.4	-0.1
Leg predicted mass (left)	2.0	10.5	19.7	-2.5	-3.5	-4.0	-3.7	-4.3	-3.6	-3.0	-3.9	4.4	-4.4	-2.2	-2.3	-2.1	-2.1	-0.6	-2.4	-3.9	-2.3
Happiness	2.0	2.4	5.4	1.7	1.3	1.8	1.8	1.7	1.6	2.3	1.5	0.4	1.8	1.5	1.6	1.3	1.2	1.2	1.7	1.5	0.7
Leg fat-free mass (right)	2.0	10.8	20.2	-2.7	-3.5	-4.1	-3.7	-4.3	-3.7	-2.8	-4.0	4.5	-4.4	-2.3	-2.4	-2.1	-2.2	-0.7	-2.5	-4.0	-2.5
Alzheimer’s Disease (including proxy)	1.9	2.8	6.7	0.8	2.4	2.3	2.2	2.2	1.4	2.1	1.6	-1.3	2.6	1.4	2.0	1.0	1.0	-0.3	1.0	1.8	0.1
Sensitivity / hurt feelings	1.9	3.2	6.7	-2.4	-2.1	-2.4	-2.6	-1.9	-1.3	-2.3	-1.6	-0.4	-2.1	-2.5	0.2	-1.1	-1.1	-1.6	-1.4	-1.8	-0.9
Leg fat-free mass (left)	1.9	10.3	19.5	-2.5	-3.6	-4.0	-3.6	-4.3	-3.6	-2.9	-3.9	4.4	-4.3	-2.2	-2.2	-2.1	-2.1	-0.6	-2.4	-3.8	-2.3
Relative age voice broke	1.9	2.9	5.9	1.6	1.4	1.7	1.6	1.8	2.4	0.3	2.3	-2.3	1.8	1.5	1.2	1.5	1.7	0.4	1.6	1.6	2.1
Osteoarthritis (self-reported)	1.9	2.5	4.9	2.2	2.1	2.0	1.6	1.4	1.1	1.8	1.1	0.2	1.5	1.9	1.0	1.6	1.6	1.5	2.2	0.9	1.0
Leg predicted mass (right)	1.9	10.3	19.9	-2.6	-3.5	-4.0	-3.6	-4.2	-3.7	-2.7	-3.9	4.5	-4.3	-2.2	-2.4	-2.0	-2.1	-0.7	-2.4	-3.9	-2.5
Sitting height	1.8	13.0	32.5	-1.7	-5.2	-4.2	-4.4	-3.9	-3.8	-4.9	-3.9	4.0	-5.7	-1.7	-4.1	-0.8	-0.7	-0.9	-2.6	-4.7	-0.6
Whole body fat-free mass	1.8	10.1	20.8	-2.0	-3.8	-3.9	-3.7	-4.1	-3.7	-2.8	-4.0	4.4	-4.6	-1.8	-2.6	-1.5	-1.7	-0.4	-2.1	-4.1	-2.0
Whole body water mass	1.8	10.2	21.0	-2.0	-3.8	-3.9	-3.7	-4.1	-3.7	-2.8	-4.0	4.5	-4.6	-1.8	-2.7	-1.6	-1.7	-0.4	-2.0	-4.1	-2.0
Ever had prostate specific antigen (PSA) test	1.8	2.0	5.0	-1.2	-2.0	-2.2	-2.2	-1.7	-1.1	-0.8	-1.4	-0.5	-1.3	-1.3	-1.8	-0.5	-0.7	-1.1	-1.6	-1.7	-0.2
Alcohol intake versus 10 years previously	1.7	2.5	8.7	0.5	2.8	1.3	2.1	1.1	1.7	1.6	1.7	-0.2	1.0	1.0	2.9	-0.4	-0.3	1.7	1.1	2.6	0.4
Arm fat-free mass (right)	1.7	8.9	19.3	-1.8	-3.7	-3.7	-3.5	-3.8	-3.4	-2.3	-3.7	4.3	-4.4	-1.5	-2.4	-1.3	-1.5	-0.3	-1.8	-4.0	-1.9
Illnesses of siblings: Diabetes	1.7	2.1	4.4	-1.5	-1.3	-2.0	-1.5	-1.7	-1.6	-0.9	-1.5	1.2	-1.4	-2.1	-0.9	-1.7	-1.8	0.1	-1.5	-0.9	-0.9
Medication: Aspirin	1.7	2.3	6.0	-1.2	-1.7	-1.2	-2.1	-1.1	-1.7	-1.1	-1.7	-0.8	-1.5	-1.3	-2.0	0.5	0.3	-2.5	-1.5	-2.2	-0.9
Basal metabolic rate	1.7	9.3	18.7	-2.2	-3.6	-3.9	-3.5	-4.0	-3.4	-2.8	-3.7	4.0	-4.3	-1.9	-2.2	-1.6	-1.7	-0.6	-2.1	-3.9	-2.0
Arm predicted mass (right)	1.6	8.0	18.0	-1.6	-3.4	-3.4	-3.2	-3.5	-3.4	-1.8	-3.6	4.2	-4.2	-1.4	-2.4	-1.5	-1.6	-0.1	-1.7	-3.7	-1.9
Comparative height size at age 10	1.6	8.7	32.9	-0.3	-5.7	-3.1	-3.9	-2.8	-2.4	-4.6	-2.6	1.9	-4.3	-0.2	-3.6	1.5	1.4	-0.9	-1.1	-4.0	1.1
Hypothyroidism (self reported)	1.5	3.5	7.3	2.2	2.0	2.7	2.4	2.4	1.7	1.1	1.9	-0.9	2.3	2.0	1.4	1.9	1.9	0.5	2.0	1.9	1.0
Ever had hysterectomy (womb removed)	1.5	1.6	4.8	0.2	2.2	1.5	1.4	1.6	1.4	1.1	1.4	-1.7	1.9	-0.1	1.0	1.1	1.1	-0.8	1.0	1.2	-0.1
Hearing difficulty/problems with background noise	1.5	2.4	5.2	-1.1	-1.6	-1.9	-2.0	-2.3	-1.8	-0.6	-1.9	0.9	-1.9	-1.3	-1.8	-1.1	-1.1	-0.7	-1.7	-1.9	-0.6
Trunk fat-free mass	1.5	8.7	18.9	-1.5	-3.8	-3.5	-3.5	-3.7	-3.4	-2.6	-3.7	4.1	-4.3	-1.4	-2.7	-1.0	-1.2	-0.4	-1.7	-4.0	-1.6
Trunk predicted mass	1.5	8.8	18.8	-1.5	-3.7	-3.5	-3.5	-3.7	-3.5	-2.6	-3.8	4.2	-4.3	-1.4	-2.8	-1.1	-1.3	-0.4	-1.8	-4.0	-1.7
Standing height	1.5	14.5	44.4	-0.5	-6.7	-4.0	-4.9	-3.6	-4.0	-5.7	-4.1	3.3	-4.8	-1.3	-4.9	0.7	0.9	-1.6	-2.1	-5.7	0.0
Medication: Paracetamol	1.5	2.4	5.7	1.1	1.6	1.1	1.5	1.0	2.4	1.5	2.1	-1.1	1.5	2.0	2.2	0.5	0.7	1.4	1.9	1.7	1.2
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	8.3	-0.5	0.1	-0.8	-0.2	-1.1	-1.8	0.8	-1.6	2.9	-1.1	-0.8	-1.3	-1.9	-1.9	0.8	-1.1	-0.9	-1.5
Medication: Aspirin	1.5	1.9	5.9	-0.8	-1.7	-0.9	-2.0	-0.8	-1.5	-0.8	-1.6	-1.0	-1.3	-0.9	-1.9	0.9	0.8	-2.4	-1.0	-2.1	-0.5
Wears glasses or contact lenses	1.5	1.7	3.6	1.7	1.2	1.8	1.1	1.6	0.9	0.1	1.2	-0.8	1.7	1.1	0.5	1.9	1.9	0.2	1.5	1.0	1.3
Arm fat-free mass (left)	1.5	7.4	15.8	-1.8	-3.3	-3.3	-3.1	-3.4	-3.2	-2.2	-3.4	3.7	-4.0	-1.5	-2.3	-1.2	-1.4	-0.5	-1.8	-3.6	-1.8
Neck or shoulder pain in last month	1.4	1.9	3.7	-1.8	-1.6	-1.8	-1.9	-1.4	-1.1	-1.6	-1.1	-1.3	-0.9	-1.6	-0.1	-0.5	-0.6	-1.8	-1.7	-1.5	-0.8
Risk taking	1.4	2.0	3.5	-1.6	-0.8	-1.6	-1.6	-1.5	-1.7	-0.3	-1.7	0.7	-1.9	-1.2	-1.4	-1.3	-1.3	-1.2	-1.7	-1.7	-1.4
Height	1.3	25.8	86.8	-0.6	-9.3	-5.2	-6.9	-4.6	-5.4	-7.6	-5.4	3.7	-6.0	-0.8	-6.5	1.7	1.8	-2.2	-2.2	-7.6	0.4
Financial difficulties in last 2 years	1.3	1.7	4.2	1.3	0.3	1.0	1.0	1.4	1.5	0.9	1.6	-1.1	1.3	1.6	1.6	1.8	2.0	0.2	1.3	0.6	1.5
Noisy workplace	1.3	1.6	5.9	1.6	0.2	1.4	0.7	1.4	0.4	0.5	0.6	-1.0	1.5	1.6	0.4	2.4	2.3	-0.5	1.7	0.0	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	1.9	5.1	-1.6	-1.1	-1.8	-1.4	-2.1	-1.2	-0.5	-1.4	1.2	-2.3	-1.2	-0.9	-1.7	-1.8	0.2	-1.4	-1.0	-0.3
Mood swings	1.3	2.4	7.1	-1.8	-2.0	-2.3	-1.8	-2.1	-1.0	-0.6	-1.3	1.3	-2.7	-1.2	0.4	-1.7	-1.6	0.0	-1.5	-1.3	-0.6
Tinnitus: Yes, now most or all of the time	1.3	1.5	5.9	1.8	1.2	1.2	1.1	1.1	0.1	2.4	0.1	0.9	0.7	1.6	-0.6	1.3	1.0	1.5	1.4	0.6	0.9
Unable to work because of sickness or disability	1.3	1.7	4.4	-2.1	-0.5	-2.0	-1.7	-1.6	-0.8	-1.3	-1.0	-0.1	-0.9	-1.3	0.4	-1.3	-1.2	-1.2	-1.5	-1.3	-1.2
Hearing difficulty/problems: Yes	1.2	1.9	9.0	-0.6	-0.4	-1.3	-0.7	-1.6	-1.5	0.2	-1.4	3.0	-2.1	-0.7	-0.9	-2.0	-1.7	1.1	-0.9	-0.6	-0.6
Medication: Metformin	1.2	1.8	3.9	-1.2	-0.8	-1.9	-1.1	-1.7	-0.9	0.7	-1.1	1.7	-2.0	-1.1	-0.1	-1.8	-2.0	1.1	-0.7	-0.5	-1.4
Impedance of leg (right)	1.2	5.6	16.6	2.4	0.6	2.2	1.7	2.8	2.7	-0.4	3.0	-4.1	2.4	2.1	1.2	2.6	2.9	0.2	1.7	1.9	3.3
Stomach or abdominal pain in last month	1.2	1.5	6.5	-1.0	0.8	-0.9	-0.1	-0.8	-0.8	0.3	-0.8	2.5	-0.8	-0.4	0.9	-2.3	-2.1	0.8	-0.7	0.0	-1.8
Qualifications: None of the above	1.2	2.7	7.4	2.6	0.7	1.4	1.3	1.3	1.5	1.3	1.5	-0.2	0.6	2.2	1.2	1.5	1.6	2.4	2.7	1.2	1.8
Weight	1.2	6.1	11.1	-2.4	-3.0	-3.3	-2.9	-3.3	-2.6	-2.7	-2.8	2.5	-3.2	-2.0	-1.0	-1.8	-1.8	-0.8	-1.9	-2.8	-1.8
Wheeze or whistling in the chest in last year	1.2	2.1	5.6	-1.1	-2.0	-2.4	-1.6	-2.3	-1.2	0.3	-1.3	1.1	-2.0	-1.0	-0.3	-1.7	-1.6	0.8	-1.5	-1.0	0.4
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	3.8	0.9	0.8	1.3	1.1	1.5	1.5	0.5	1.3	-1.9	1.6	0.8	1.0	1.1	1.1	-0.1	1.2	1.1	1.1
Back pain experienced in last month	1.2	1.7	6.6	0.3	1.8	0.5	1.7	0.6	1.9	1.0	1.7	-0.9	0.5	1.1	2.6	-1.1	-0.8	1.4	0.6	2.0	0.7
Arm predicted mass (left)	1.2	6.3	13.6	-1.6	-3.0	-3.1	-2.9	-3.2	-3.0	-1.8	-3.2	3.6	-3.7	-1.3	-2.1	-1.2	-1.4	-0.3	-1.5	-3.3	-1.7
Hand grip strength (left)	1.1	2.9	9.0	-0.3	-1.8	-1.6	-1.8	-1.8	-1.9	-1.5	-2.0	2.1	-3.0	0.1	-3.0	-0.1	-0.3	-0.2	-1.3	-2.2	-0.3
Tinnitus: Yes, but not now, but have in the past	1.1	1.1	6.3	-0.5	-1.7	-1.4	-1.3	-1.0	-0.4	-2.5	-0.6	-0.1	-1.1	-0.6	-1.1	0.3	0.3	-0.5	-0.9	-1.1	0.6
Medication: Levothyroxine sodium	1.1	1.8	4.1	1.6	1.4	2.0	2.0	1.8	1.0	1.2	1.1	0.6	1.6	1.3	0.7	1.2	1.1	0.8	1.7	1.2	0.2
Mouth/teeth dental problems	1.1	1.7	4.0	-2.0	-1.3	-1.6	-1.3	-1.8	-1.1	-1.0	-1.1	1.0	-1.1	-1.9	-0.6	-1.2	-1.4	-0.6	-1.4	-0.8	-0.9
Mouth/teeth dental problems: Dentures	1.1	1.8	4.4	1.6	1.9	1.9	1.4	1.8	0.9	1.4	1.1	-1.0	1.0	1.0	1.2	0.9	0.8	0.9	2.1	1.1	-0.1
Medication: Lansoprazole	1.1	1.3	3.8	0.3	1.9	1.6	1.2	1.5	0.9	0.9	0.9	-1.6	1.9	0.9	1.2	0.3	0.4	-0.5	0.5	1.1	-0.2
Medication: Ibuprofen	1.1	1.3	5.8	-1.4	-0.4	-1.0	-1.1	-1.1	-0.7	-1.1	-0.9	-0.6	-0.7	-0.9	-0.4	-0.8	-0.7	-2.4	-2.0	-1.3	-1.0
Supplements: Fish oil (including cod liver oil)	1.1	1.5	3.0	1.3	1.7	1.5	1.0	1.4	1.1	1.6	1.1	-0.7	1.5	0.8	0.3	1.5	1.7	-0.3	1.0	0.7	1.0
Illnesses of father: High blood pressure	1.1	1.4	3.9	-1.2	-2.0	-1.6	-1.8	-1.7	-0.8	-1.4	-1.0	-0.1	-1.0	-1.1	-1.1	0.2	-0.1	-0.9	-1.0	-1.5	0.3
Ulcerative Colitis (UC)	1.0	1.8	5.2	-1.3	-0.3	-1.7	-1.0	-1.8	-1.5	-0.7	-1.4	1.1	-1.6	-0.8	-0.1	-2.0	-2.3	0.6	-1.3	-0.9	-1.6
Impedance of leg (left)	1.0	5.1	16.4	2.1	0.6	2.1	1.7	2.8	2.7	-0.1	3.0	-4.0	2.5	1.8	1.2	2.4	2.7	-0.0	1.5	1.9	2.9
Hip circumference	1.0	4.5	9.8	-2.5	-2.2	-3.0	-2.3	-3.1	-1.8	-2.6	-2.1	1.5	-2.7	-1.9	0.1	-2.1	-2.0	-0.6	-1.8	-1.9	-1.5
Number of children fathered	1.0	1.1	3.8	-1.4	-0.7	-1.9	-1.2	-1.8	-0.1	-1.3	-0.5	-1.3	-1.1	-1.0	-0.6	-0.7	-1.0	0.1	-1.0	-0.5	0.3
Angina (self-reported)	1.0	1.3	3.2	-0.7	-1.8	-1.7	-1.6	-1.8	-1.4	0.2	-1.5	0.5	-1.0	-0.4	-1.7	-0.1	-0.4	-0.1	-1.1	-1.3	-0.0
Friendships satisfaction	1.0	1.2	2.3	1.1	1.1	1.5	1.3	1.5	1.4	0.0	1.2	-0.7	1.5	1.0	1.2	0.8	0.7	0.4	1.3	1.1	0.2
Financial situation satisfaction	1.0	1.2	5.0	0.9	1.6	1.5	1.7	1.6	0.7	2.2	0.9	0.1	1.6	0.6	0.6	-0.1	0.1	0.3	0.3	1.2	0.1
Medication: Bendroflumethiazide	1.0	1.5	8.0	-0.1	1.5	0.9	0.9	0.9	1.8	0.4	1.6	-2.8	0.6	0.5	1.9	1.0	0.8	-0.4	0.8	1.5	0.5
Medication: Atorvastatin	1.0	1.2	4.1	-0.5	-2.0	-0.9	-1.7	-1.0	-1.3	-1.0	-1.5	0.6	-0.0	-0.3	-1.4	0.5	0.3	-0.9	-0.3	-1.9	-0.7
Schizophrenia vs Biploar Disorder	0.9	1.1	6.2	0.2	-0.1	1.5	0.5	1.3	0.8	-0.2	0.9	-2.5	1.6	-0.0	0.5	1.3	1.1	-0.6	0.9	0.9	0.9
Crohns Disease (2017)	0.9	2.0	6.9	-2.0	-0.8	-1.8	-1.2	-1.5	-0.6	-1.1	-0.5	-0.0	-2.0	-1.0	0.4	-2.1	-2.0	-0.9	-2.6	-0.7	-1.1
Major Depression (MDD)	0.9	1.1	3.8	-0.7	0.7	-0.4	0.6	-0.3	1.2	-0.6	1.4	-1.7	-0.2	-0.6	2.0	-1.2	-1.2	1.0	-0.0	1.6	0.3
Number of treatments/medications taken	0.9	1.6	4.2	-0.9	-1.3	-1.8	-2.0	-1.5	-0.8	-0.8	-0.9	-1.9	-1.1	-0.7	-1.0	0.4	0.3	-1.8	-1.5	-1.7	0.5
High blood pressure (mother)	0.9	1.3	3.4	-0.7	-1.4	-1.7	-1.6	-1.5	-0.8	-1.1	-0.9	0.1	-1.5	-0.9	-1.8	-0.2	-0.2	-0.5	-1.4	-1.4	0.5
Birth weight of first child	0.9	1.6	8.8	0.4	1.0	1.0	0.7	1.2	1.5	-1.2	1.5	-3.0	1.5	0.7	1.6	1.2	1.1	-1.2	0.0	0.6	0.7
Glaucoma (self-reported)	0.9	1.1	3.0	1.6	0.4	1.7	0.9	1.2	-0.3	1.4	-0.1	0.8	1.2	1.1	-0.9	1.5	1.4	0.0	1.1	0.1	0.3
Medication: Ventolin 100micrograms inhaler	0.9	1.1	3.1	1.3	0.8	0.1	0.6	0.0	1.4	0.5	1.3	-0.1	0.1	1.5	1.4	0.7	0.8	1.8	1.1	0.9	1.6
Supplements: Vitamin C	0.9	1.1	6.9	-0.6	2.6	0.1	1.0	0.1	1.1	1.1	1.0	-0.4	0.1	0.3	1.9	-1.0	-0.8	0.1	-0.2	1.5	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	4.0	0.3	0.7	0.8	1.0	0.5	1.5	1.4	1.3	-1.8	0.6	0.7	2.0	0.5	0.4	-0.0	0.3	1.2	0.7
Qualifications: nursing, teaching	0.9	1.3	3.7	-1.3	-1.9	-1.7	-1.1	-1.5	-1.0	-0.3	-1.1	1.0	-0.9	-1.0	-1.1	-1.4	-1.4	0.2	-1.5	-0.6	0.1
Mineral and other dietary supplements	0.9	1.2	2.9	-0.9	-1.7	-1.2	-1.0	-1.1	-1.5	-1.3	-1.3	1.3	-1.1	-0.4	-0.9	-0.9	-1.1	0.2	-0.8	-1.1	-1.2
Eye problems/disorders: Glaucoma	0.9	1.0	2.4	1.5	0.1	1.4	0.6	0.9	-0.1	1.4	-0.0	1.1	1.0	1.2	-1.2	1.4	1.3	0.5	1.3	0.1	0.4
Pain experienced in last month	0.9	1.6	4.6	-0.8	-1.1	-0.0	-0.9	-0.1	-2.1	-0.7	-1.7	1.2	-0.5	-1.4	-2.2	0.3	0.1	-1.9	-0.8	-1.4	-1.9
Basal cell carcinoma (self-reported)	0.9	1.1	2.2	0.8	1.3	0.7	1.0	0.6	1.2	1.3	1.0	-1.2	1.0	0.8	0.9	0.9	0.8	0.8	1.0	1.1	1.5
Ovarian Cancer	0.8	1.1	7.9	-1.2	-1.1	-1.1	-1.4	-0.9	-0.3	-2.8	-0.5	-0.5	-1.2	-0.4	0.2	0.1	0.1	-1.1	-0.7	-1.0	-0.3
Lupus	0.8	1.3	4.8	0.8	1.5	1.6	1.4	1.6	0.5	0.2	0.9	0.6	2.2	0.8	1.0	0.7	0.8	0.6	1.4	1.1	-0.1
Eye problems/disorders: Diabetes related eye disease	0.8	0.8	2.6	-0.2	0.3	0.2	0.1	-0.4	-1.3	1.3	-1.2	1.4	-0.3	-0.4	-0.9	-1.2	-1.4	0.2	-0.6	-0.1	-1.6
Townsend deprivation index at recruitment	0.8	1.1	3.2	0.9	0.5	0.5	0.7	0.3	1.4	0.4	1.3	-0.6	-0.7	1.8	1.6	1.1	1.0	1.0	1.0	0.8	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.7	1.4	0.7	1.1	1.0	0.8	0.5	0.9	0.6	1.4	0.5	1.6	1.4	0.5	0.6	1.6	1.5	0.7	0.4
Hair/balding pattern: Pattern 3	0.8	1.2	5.0	0.6	2.2	1.8	1.3	1.4	0.7	0.9	0.6	-0.4	1.4	-0.1	1.0	1.3	1.1	-0.0	1.3	0.8	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	3.1	-1.3	-0.2	-1.0	-1.0	-1.2	-0.5	-0.8	-0.8	-0.1	-1.1	-0.6	-0.3	-1.1	-0.9	-1.7	-1.8	-1.1	-0.8
Exposure to tobacco smoke at home	0.8	0.8	2.6	-1.1	0.7	-0.9	0.1	-0.6	1.0	-0.6	0.7	-1.6	-1.2	-0.4	1.6	-1.1	-1.2	0.5	-0.3	0.9	-0.1
Loud music exposure frequency	0.8	0.9	3.2	1.0	1.0	0.2	0.8	0.2	0.5	1.6	0.6	-0.1	-0.3	1.3	1.2	0.5	0.4	1.8	1.7	0.8	0.5
Eye problems/disorders: None of the above	0.8	1.0	2.9	-1.4	-0.6	-1.0	-0.7	-0.8	-0.7	-0.4	-0.7	-0.5	-0.8	-0.9	0.1	-1.7	-1.5	-1.2	-1.2	-0.5	-1.4
Mouth/teeth dental problems: Loose teeth	0.8	0.9	3.6	0.5	1.9	1.0	1.5	1.0	0.4	1.0	0.8	0.6	1.1	0.6	1.0	-0.1	0.1	0.8	0.9	1.4	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	4.9	-0.1	0.5	1.6	0.5	1.5	-0.8	1.1	-0.5	0.0	1.2	-0.6	0.0	-0.2	-0.1	-2.2	-0.7	-0.1	-1.9
Chest pain or discomfort	0.8	1.2	4.9	0.5	1.8	-0.3	0.9	-0.5	0.8	2.1	0.5	1.3	-0.2	0.5	1.4	-1.0	-1.0	2.2	0.5	0.8	0.2
Bipolar Disorder (2018)	0.7	1.1	5.7	1.6	1.6	0.3	1.1	0.4	0.6	0.9	0.6	2.4	-0.1	1.3	0.3	0.3	0.3	1.9	1.0	0.5	0.1
Depressed Affect (Nagel 2018)	0.7	1.5	5.5	-0.8	-2.3	-1.9	-1.7	-1.5	-1.1	-0.6	-1.1	0.8	-2.2	-0.5	-0.1	-0.8	-0.7	0.3	-0.8	-1.2	0.1
Irritable Bowel Disease (IBD)	0.7	1.7	4.6	-1.6	-0.6	-1.8	-1.1	-1.7	-1.0	-0.8	-0.9	0.3	-1.7	-0.7	0.1	-2.0	-2.2	-0.1	-2.0	-0.7	-1.4
Waist Hip Ratio (WHR)	0.7	3.1	11.2	1.5	0.8	2.0	1.1	2.3	1.4	-0.4	1.6	-2.5	3.4	1.1	0.7	2.6	2.8	-1.3	1.2	0.5	1.1
Frequency of depressed mood in last 2 weeks	0.7	1.0	3.4	1.7	-0.7	0.6	0.3	0.5	-0.1	-0.0	0.0	1.0	0.5	1.6	0.0	1.6	1.8	0.5	1.1	-0.4	1.5
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	3.0	-1.0	0.3	-0.8	-0.5	-1.1	-0.6	0.2	-0.7	1.4	-1.0	-0.8	-0.1	-1.7	-1.6	-0.1	-1.1	-0.5	-1.2
Angina	0.7	0.9	2.7	-0.6	-1.6	-1.5	-1.3	-1.5	-1.1	0.3	-1.2	0.2	-0.8	-0.3	-1.4	0.0	-0.3	-0.0	-1.0	-1.0	0.1
Medication: Atenolol	0.7	0.9	3.6	1.0	-0.5	0.1	-0.4	0.4	0.7	0.6	0.6	-1.0	0.9	1.1	-0.2	1.9	1.8	0.3	0.8	-0.3	1.4
Diabetes (self-reported)	0.7	1.0	4.6	-1.1	0.8	-0.4	0.2	-0.6	-0.3	1.4	-0.3	0.6	-0.4	-0.7	0.6	-1.9	-2.1	1.0	-0.4	0.9	-1.6
Impedance of arm (right)	0.7	3.0	8.8	1.3	0.8	1.9	1.5	2.3	2.1	-1.1	2.4	-3.0	2.6	0.7	1.3	1.1	1.6	-0.3	0.9	2.0	1.9
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	3.6	-1.7	-0.8	-1.9	-1.1	-1.4	-0.3	-0.5	-0.5	0.5	-1.2	-0.5	0.7	-1.8	-1.5	0.2	-1.5	-0.4	-0.2
Depression (self-reported)	0.7	0.9	4.0	-0.7	-0.3	-1.4	-0.9	-1.4	-0.4	-0.6	-0.8	1.7	-2.0	-0.5	0.0	-0.6	-0.6	0.7	-0.6	-0.6	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.1	7.1	0.2	-2.0	-1.3	-1.7	-1.1	-1.0	-2.2	-1.2	0.4	-2.7	0.3	-1.7	1.5	1.3	-0.7	-0.5	-2.2	1.1
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.2	-1.0	-1.2	-0.9	-1.1	-0.9	-1.4	-1.5	-1.3	0.0	-0.4	-1.1	-1.0	-0.2	-0.2	-1.4	-1.2	-1.4	-0.9
Exposure to tobacco smoke outside home	0.7	0.9	2.9	-0.8	-0.3	-0.7	-0.3	-0.8	-1.2	-0.2	-1.2	1.5	-0.4	-0.5	-0.5	-1.7	-1.7	0.2	-0.9	-0.3	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	3.7	1.3	0.2	1.2	0.1	1.0	0.4	0.8	0.4	-0.5	0.5	0.9	-0.1	1.9	1.7	0.1	1.2	-0.2	1.2
Age at first live birth	0.7	1.3	4.9	-0.6	-1.4	-0.6	-0.4	-0.6	-1.4	0.6	-1.5	2.2	-1.2	-0.5	-1.8	-1.2	-1.3	0.2	-1.0	-0.7	-1.2
Loneliness, isolation	0.7	0.9	4.8	-0.2	-0.6	-0.6	-0.4	-0.7	-1.5	1.1	-1.5	2.2	-1.2	0.1	-0.9	-0.7	-0.6	-0.2	-0.9	-0.9	-0.5
Long-standing illness, disability or infirmity	0.7	1.1	2.3	1.5	1.1	0.8	1.0	0.8	1.1	1.4	1.1	-0.3	1.3	1.2	1.0	0.9	1.0	1.0	0.9	0.9	1.3
Commuting to job workplace: Walk	0.7	0.8	3.1	0.6	-1.5	0.1	-0.8	0.4	-0.3	-0.8	-0.2	-0.4	0.1	0.4	-0.9	1.6	1.8	-1.1	0.1	-1.0	0.9
Eye problems/disorders: Cataract	0.7	0.8	1.8	0.5	1.1	0.7	0.6	0.8	1.3	-0.8	1.3	-1.2	0.4	0.5	0.9	1.1	1.1	-0.0	0.6	0.6	1.1
Medication: Gliclazide	0.7	0.8	2.3	-1.3	-0.5	-1.1	-0.5	-0.8	-0.0	-0.3	-0.1	0.9	-1.2	-0.7	1.1	-1.5	-1.4	0.6	-0.8	0.3	-0.8
Mother’s age at death	0.7	0.9	2.2	1.0	0.3	0.9	0.7	1.1	0.8	-1.1	1.0	-0.9	1.2	0.3	0.1	1.2	1.2	0.5	1.5	0.6	1.0
Average weekly beer plus cider intake	0.7	1.1	5.1	-0.0	0.6	0.8	0.7	0.1	-0.5	2.2	-0.3	2.3	0.4	-0.0	0.9	-1.2	-1.2	0.9	0.5	0.6	-1.5
Myopia	0.7	1.0	4.8	-1.2	-0.8	-1.1	-1.2	-1.4	-0.8	-2.2	-0.7	-0.2	-1.0	-1.2	-0.3	-0.2	-0.1	-0.9	-0.8	-0.9	0.3
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.3	-1.1	-0.4	-1.3	-0.8	-1.5	-0.7	-0.2	-0.8	1.1	-1.5	-0.5	-0.2	-1.2	-1.3	0.2	-0.8	-0.7	-1.0
Alcohol drinker status: Previous	0.7	0.8	4.1	-0.6	-0.5	-0.1	-0.8	-0.0	-1.1	-1.7	-0.8	0.0	0.0	-0.5	-0.8	0.5	0.6	-2.0	-0.8	-1.3	-0.6
Impedance of whole body	0.7	3.7	10.9	1.8	0.3	1.8	1.4	2.4	2.2	-0.7	2.6	-3.3	2.5	1.4	0.9	1.9	2.2	-0.0	1.1	1.8	2.6
Blood Eosinophil Count	0.6	4.3	8.1	-2.9	-2.0	-2.6	-2.5	-2.2	-1.5	-2.3	-1.6	-0.8	-1.9	-2.8	-0.8	-1.8	-1.7	-2.4	-2.8	-1.7	-1.4
Allergy or Eczema	0.6	1.5	9.8	0.1	1.1	1.0	1.0	1.2	1.5	-0.4	1.3	-3.1	1.5	-0.6	1.4	0.6	0.6	-0.8	0.5	1.3	0.5
Lung FVC	0.6	3.0	9.1	0.1	-3.0	-1.3	-2.3	-1.3	-2.0	-1.7	-2.0	0.9	-2.1	-0.0	-2.3	1.8	1.4	-0.6	-0.1	-2.8	0.7
Pack years adult smoking proportion	0.6	0.9	2.9	1.0	0.8	1.0	1.2	0.8	0.8	0.9	1.0	-0.6	0.3	1.3	1.7	0.9	1.0	0.3	0.6	0.7	1.1
Waist circumference	0.6	2.3	4.5	-1.9	-1.4	-2.1	-1.8	-2.1	-1.4	-1.7	-1.5	0.7	-1.3	-1.5	0.4	-1.2	-1.1	-1.2	-1.5	-1.7	-1.4
Falls in the last year	0.6	0.8	4.0	-0.7	-1.4	-1.0	-1.1	-1.1	0.1	-0.6	-0.1	-2.0	-1.0	0.2	0.3	-0.2	-0.3	-0.8	-1.0	-0.7	0.5
Forced expiratory volume in 1-second (FEV1)	0.6	2.2	6.0	-0.3	-1.8	-1.3	-1.8	-1.3	-1.5	-2.4	-1.6	0.8	-2.4	-0.4	-1.8	1.0	0.7	-1.0	-0.7	-2.4	0.0
Length of working week for main job	0.6	0.7	1.9	-0.1	-0.1	-1.0	-0.8	-1.2	-0.8	1.2	-1.1	0.9	-1.1	0.1	-1.4	-0.7	-0.8	0.9	-0.1	-0.5	0.0
Tense / ‘highly strung’	0.6	1.0	2.7	-0.6	-1.5	-0.8	-1.3	-0.4	-0.2	-0.9	-0.3	-1.5	-1.0	-0.4	-0.1	1.0	1.0	-1.7	-0.9	-1.2	0.7
Worry too long after embarrassment	0.6	1.0	3.2	-1.5	-0.9	-1.8	-1.3	-1.1	0.3	-0.5	0.1	-1.8	-1.4	-0.3	0.9	-0.5	-0.6	-0.7	-1.4	-0.3	0.4
Medication: Omeprazole	0.6	0.7	2.7	0.1	1.6	0.5	1.1	0.2	0.8	1.1	0.8	-1.2	0.2	-0.1	1.4	-0.6	-0.7	0.3	-0.0	1.2	-0.1
Mean time to correctly identify matches	0.6	1.1	2.7	-1.0	0.9	0.8	1.0	0.6	1.1	0.2	1.1	-0.9	1.1	-1.1	1.6	-1.5	-1.2	-0.3	0.1	1.6	-1.3
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.8	-1.0	0.0	-0.5	-0.1	-0.6	-0.6	0.1	-0.7	1.0	-0.3	-0.8	-0.2	-1.6	-1.7	-0.1	-1.0	-0.1	-1.4
Miserableness	0.6	1.1	4.2	-0.9	-1.0	-1.5	-0.8	-1.1	-0.3	-0.4	-0.4	1.3	-2.1	-0.1	1.8	-1.3	-1.0	0.9	-0.3	-0.4	-0.2
Medication: Paracetamol	0.6	1.0	2.4	0.5	0.9	0.8	0.9	0.7	1.5	1.5	1.2	-0.8	1.3	1.2	1.3	0.4	0.5	0.4	1.1	0.9	0.4
Neuroticism (Nagel 2018)	0.5	1.1	4.4	-0.9	-2.1	-1.7	-1.6	-1.2	0.1	-0.9	-0.1	-1.3	-1.6	-0.4	0.9	0.0	0.1	-0.5	-0.8	-0.5	1.0
Verbal and Numeric Reasoning (VNR)	0.5	1.1	2.3	-0.4	-0.7	-0.7	-0.4	-1.2	-1.3	1.2	-1.4	1.4	-0.4	-0.7	-1.4	-1.4	-1.5	0.0	-0.9	-0.8	-1.5
Body Mass Index (BMI) (2010)	0.5	0.7	2.5	-0.1	-1.1	-0.2	-1.0	-0.4	-1.1	-1.2	-1.1	0.1	-0.1	-0.4	-1.0	0.5	0.7	-1.2	-0.3	-1.6	-0.1
Fasting Glucose	0.5	0.6	4.3	-0.8	-0.8	-0.5	-0.8	-0.2	0.5	-0.8	0.3	-2.1	0.2	-0.6	0.2	0.2	0.3	-1.4	-0.7	-0.2	-0.1
HDL Cholesterol	0.5	0.8	2.0	0.2	0.9	0.8	0.7	1.3	1.0	-1.4	1.1	-1.3	1.1	0.4	1.0	0.4	0.4	-0.1	0.6	1.0	0.4
Neuroticism (2016)	0.5	0.7	3.0	-0.2	0.6	0.9	0.7	1.0	0.8	1.2	1.0	-1.3	0.7	-0.0	1.7	0.5	0.4	-0.3	0.4	1.0	-0.0
Triglycerides	0.5	0.8	2.1	1.3	1.1	0.9	0.9	0.8	0.8	0.7	0.8	-0.7	0.6	0.8	0.7	0.7	0.8	0.9	1.0	0.7	1.4
Type 2 Diabetes (T2D) (2012)	0.5	0.6	3.5	1.0	0.5	0.4	0.3	0.2	0.0	1.9	0.1	1.0	0.9	0.9	0.3	0.9	0.9	1.0	0.7	-0.0	0.8
Medication for hormone replacement therapy	0.5	0.6	1.7	-1.1	-1.0	-0.5	-0.8	-0.3	-0.8	-0.2	-0.8	-1.1	0.1	-0.9	-0.6	-0.3	-0.4	-1.3	-0.8	-0.7	-0.8
Trunk fat mass	0.5	2.1	4.9	-1.8	-1.6	-2.2	-1.6	-2.0	-1.1	-2.1	-1.2	0.8	-1.5	-1.6	0.5	-1.5	-1.4	-0.5	-1.3	-1.2	-1.0
Neuroticism score	0.5	1.0	3.5	-1.1	-1.9	-1.5	-1.4	-1.0	-0.1	-1.2	-0.2	-0.3	-1.5	-0.4	1.3	-0.3	-0.3	-0.6	-1.0	-0.7	0.3
Worrier / anxious feelings	0.5	0.9	4.7	-1.1	-1.1	-0.3	-0.6	0.2	0.6	-1.1	0.6	-2.2	0.8	-0.5	1.2	0.5	0.4	-1.8	-0.8	0.1	0.2
Pulse wave Arterial Stiffness index	0.5	0.6	3.6	-0.9	-0.2	-0.9	-0.6	-0.8	0.0	-1.9	-0.0	-0.1	-0.4	-0.5	0.2	-0.9	-0.9	-0.4	-1.3	-0.3	-0.3
Peak expiratory flow (PEF)	0.5	1.2	4.1	0.0	-0.9	-0.9	-1.3	-0.7	-0.7	-2.0	-0.8	-0.1	-1.7	0.2	-1.4	1.3	1.1	-0.9	-0.2	-1.7	0.6
Blood clot in the leg (DVT)	0.5	0.7	2.1	-0.9	-0.4	-1.3	-0.7	-1.5	-0.5	-0.1	-0.7	0.7	-1.4	-0.5	-0.1	-1.1	-1.1	0.2	-0.7	-0.6	-0.7
Headache pain in last month	0.5	0.8	2.6	-1.2	0.5	-0.2	0.2	-0.2	0.4	-0.5	0.2	-1.0	0.5	-1.0	1.3	-1.6	-1.5	-1.0	-1.1	0.6	-1.0
Medication: Amlodipine	0.5	0.7	1.8	0.6	0.6	0.6	0.9	0.5	1.1	1.2	1.0	-1.2	0.5	0.5	0.7	-0.2	-0.2	1.2	0.6	1.4	0.8
Leg pain on walking	0.5	0.6	2.3	-0.9	0.9	0.0	0.4	-0.1	0.9	-0.8	0.7	-0.4	-0.2	-0.7	1.2	-1.5	-1.2	-0.5	-1.0	0.5	-0.3
Knee pain experienced in last month	0.5	0.7	4.0	-0.1	1.4	0.3	0.5	0.0	1.4	-0.0	1.2	-2.0	0.4	0.4	1.6	-0.3	-0.2	-0.2	0.3	0.8	0.3
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	3.2	0.2	-1.8	-1.2	-1.3	-1.1	-0.5	-0.7	-0.6	0.5	-0.4	0.2	-1.2	0.2	0.4	-0.1	-0.6	-1.4	0.7
Osteoporosis (self-reported)	0.5	0.6	1.4	0.4	1.0	0.8	1.0	0.5	1.0	0.9	1.1	-1.1	0.6	0.5	1.2	0.3	0.1	0.2	1.0	1.0	-0.2
Ever smoked	0.5	0.9	2.7	-1.0	-1.4	-0.9	-1.2	-0.9	-0.8	-0.3	-0.9	0.7	-1.6	-1.3	-0.2	-0.7	-0.7	-0.4	-0.4	-1.1	-1.0
Irritability	0.5	0.8	3.8	-1.0	-0.9	-0.8	-0.2	-0.5	1.0	-0.8	0.9	-1.5	-0.5	-0.1	2.0	-0.6	-0.4	-0.7	-1.0	0.4	0.4
Fractured/broken bones in last 5 years	0.5	0.6	2.3	-0.1	-0.4	0.3	0.4	0.4	1.1	-0.2	1.1	-1.1	1.0	0.3	1.1	0.7	0.8	0.5	0.9	0.9	1.5
Commuting to job workplace: Cycle	0.5	0.6	2.0	0.7	1.4	1.0	1.2	0.9	0.7	1.1	0.6	0.4	-0.0	-0.5	0.2	0.1	0.2	0.9	0.9	0.8	0.7
Supplements: Calcium	0.5	0.6	1.9	0.1	0.9	0.3	0.9	0.3	1.4	0.1	1.2	-1.1	0.2	-0.3	1.1	-0.6	-0.5	0.6	0.8	1.2	-0.1
Leg fat mass (left)	0.5	2.1	4.7	-2.2	-0.9	-1.9	-1.3	-1.9	-1.2	-1.0	-1.3	1.0	-1.4	-1.8	0.7	-1.9	-1.8	-0.6	-1.3	-1.0	-1.7
Reaction Time	0.4	0.8	2.9	-1.5	0.1	0.2	0.5	0.0	0.9	-0.6	0.8	-0.5	0.3	-0.7	1.7	-1.4	-1.2	-0.4	-0.3	1.1	-1.1
Coronary Artery Disease (CAD)	0.4	0.5	1.6	0.3	0.6	0.5	0.8	0.3	0.8	0.0	1.0	-0.8	0.3	0.6	1.3	-0.3	-0.2	0.9	0.5	1.0	0.6
Crohns Disease (2012)	0.4	0.6	3.1	-0.8	0.7	0.0	0.4	0.3	1.1	-0.4	1.2	-0.9	-0.1	-0.6	1.8	-1.1	-0.8	0.2	-0.4	1.0	0.0
Rheumatoid Arthritis	0.4	0.5	1.4	-0.2	0.1	-0.7	-0.9	-0.8	-0.7	-1.0	-0.7	0.3	-1.2	-0.7	-0.9	0.1	0.2	-0.8	-0.6	-1.1	-0.1
Neuroticism	0.4	0.9	4.5	-0.6	-2.1	-1.2	-1.5	-0.7	0.1	-1.1	-0.1	-1.2	-1.0	-0.4	0.4	0.4	0.4	-0.7	-0.6	-0.7	0.8
Chronotype (morning person)	0.4	0.9	2.9	-1.7	-0.5	-0.0	0.1	0.3	0.2	-1.3	0.3	-1.0	0.1	-1.4	0.3	-1.0	-1.0	-1.6	-1.3	0.3	-1.1
Vitamin and mineral supplements	0.4	0.5	1.3	1.0	-0.6	1.1	0.4	0.9	-0.8	-0.1	-0.5	0.8	0.3	0.0	-0.9	1.0	0.8	0.3	0.8	-0.4	0.1
Average weekly fortified wine intake	0.4	0.5	2.1	-0.5	-0.6	-0.9	-0.2	-0.7	0.1	0.5	-0.1	1.5	-0.1	0.5	0.4	-1.0	-1.0	1.4	-0.2	0.0	-0.0
Fed-up feelings	0.4	0.8	4.6	-0.3	-0.6	-1.0	-0.1	-0.6	0.9	-0.8	0.9	-0.5	-1.4	0.9	2.1	-0.2	-0.2	1.3	0.5	0.5	0.8
Hayfever, allergic rhinitis or eczema	0.4	0.8	2.8	0.3	1.3	0.7	1.1	0.8	1.3	0.2	1.0	-1.7	1.0	-0.1	1.2	-0.0	0.1	0.2	0.4	1.3	0.3
Supplements: Glucosamine	0.4	0.6	2.3	-0.8	0.3	-0.4	-0.5	-0.5	-0.7	-0.4	-0.7	0.2	-0.5	-0.9	-0.3	-0.9	-0.7	-1.5	-1.3	-0.6	-1.0
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.6	-0.1	-0.1	-1.0	-0.3	-0.8	0.7	-0.8	0.5	0.5	-1.0	0.1	0.9	-0.1	-0.2	1.3	0.4	0.1	0.6
Body mass index (BMI)	0.4	1.8	4.8	-2.1	-0.0	-1.6	-0.7	-1.7	-0.9	-0.0	-1.0	1.2	-1.1	-1.4	1.2	-2.1	-2.2	0.0	-1.0	-0.3	-1.8
Nervous feelings	0.4	0.7	2.7	-0.5	-1.2	-1.0	-0.9	-0.7	0.8	-1.7	0.5	-1.0	-0.7	-0.1	0.9	0.4	0.5	-0.3	-0.3	-0.3	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	2.6	-1.3	-0.7	-0.6	-0.7	-0.5	-0.1	-0.9	-0.2	-1.0	-0.6	-1.2	0.5	-0.4	-0.3	-1.6	-0.9	-0.4	-0.6
Hair/balding pattern: Pattern 2	0.4	0.5	1.7	0.1	-1.2	-0.2	0.0	0.2	0.7	-1.3	1.0	-1.1	0.0	0.7	1.1	0.1	0.2	0.7	-0.0	0.6	1.1
Had other major operations	0.4	0.5	1.2	0.9	1.0	0.6	0.7	0.9	0.7	0.2	0.7	-0.2	1.1	0.2	0.8	0.4	0.5	0.7	1.1	0.4	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	2.9	-0.3	1.2	0.5	1.2	0.7	1.3	0.3	1.2	-0.8	1.7	0.2	1.4	-0.7	-0.6	-0.2	-0.3	1.3	-0.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.4	1.1	1.0	1.0	1.0	1.1	0.3	1.2	0.3	-0.1	0.9	0.3	-0.5	0.2	0.4	0.1	0.4	0.8	0.6
Medication: Ramipril	0.4	0.5	2.5	0.1	1.1	0.1	0.6	0.4	1.0	0.4	0.9	-1.6	0.4	0.4	0.8	0.3	0.2	0.3	0.3	1.1	0.8
Fluid intelligence score	0.4	0.8	3.3	-0.9	-0.2	-0.8	-0.1	-1.2	-0.5	1.1	-0.6	0.7	-0.1	-0.7	-0.4	-1.6	-1.8	0.3	-0.8	-0.1	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	4.0	-0.9	0.2	-0.8	-0.4	-0.3	0.2	-2.0	0.2	-0.6	-0.2	-0.3	0.4	-0.2	-0.1	-0.5	-0.6	-0.2	0.5
Illnesses of mother	0.4	0.5	1.2	1.1	0.3	1.0	0.5	0.9	0.5	0.3	0.5	-0.4	0.8	1.1	0.4	1.0	0.8	0.1	1.0	0.2	0.1
Impedance of arm (left)	0.4	1.9	5.5	1.3	0.2	1.4	1.0	1.8	1.6	-1.0	1.9	-2.3	2.0	0.8	0.7	1.1	1.5	-0.1	0.6	1.4	1.9
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.6	-0.1	0.4	-0.5	0.2	-0.3	1.0	0.7	0.9	-1.1	-0.3	0.5	1.6	-0.1	-0.0	0.9	0.6	0.8	0.9
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.0	0.8	1.0	1.0	1.1	0.5	0.4	1.1	0.3	1.4	0.4	1.0	0.1	-0.8	-0.6	0.9	0.5	0.7	-0.5
Birth weight	0.4	0.9	3.2	-0.2	-1.4	-0.0	-1.0	0.3	-0.6	-1.8	-0.6	-0.8	0.8	-0.4	-1.6	0.6	0.6	-1.6	-0.3	-1.2	-0.3
Medication: Blood pressure	0.4	0.7	2.7	-1.0	-0.8	-1.3	-0.9	-0.8	0.2	-1.0	0.1	-1.6	-0.9	-0.9	0.3	0.5	0.3	-0.3	-0.5	-0.3	0.8
Medication: Allopurinol	0.4	0.5	2.2	0.2	-0.1	1.0	0.0	0.7	-0.6	0.8	-0.2	-0.9	0.8	-0.4	-0.3	1.5	1.1	-1.2	0.4	-0.2	-0.4
Medication: Seretide 50 evohaler	0.4	0.4	1.1	0.4	0.3	0.4	0.4	0.6	1.1	0.5	0.9	-0.6	0.4	0.6	1.0	0.5	0.6	0.5	0.6	0.7	1.0
Whole body fat mass	0.4	1.8	4.0	-1.8	-1.1	-2.0	-1.2	-1.9	-0.9	-1.5	-1.0	0.9	-1.4	-1.5	0.8	-1.8	-1.6	-0.2	-1.2	-0.9	-1.2
Leg fat mass (right)	0.4	1.7	3.7	-1.9	-0.8	-1.8	-1.1	-1.7	-1.0	-1.1	-1.1	0.9	-1.3	-1.5	0.9	-1.7	-1.6	-0.4	-1.1	-0.8	-1.4
Alcohol intake frequency.	0.4	1.0	3.3	0.2	1.8	1.3	1.2	1.5	0.5	0.5	0.7	-1.3	1.5	-0.2	1.1	-0.1	0.0	-0.4	0.6	1.3	-0.3
Suffer from ‘nerves’	0.4	0.6	3.7	-0.5	-1.6	-1.0	-0.8	-0.6	0.0	-1.9	0.2	0.0	-0.7	-0.0	0.9	-0.2	-0.0	0.1	-0.3	-0.3	0.7
Overall health rating	0.4	0.9	4.3	-0.4	2.0	0.1	0.9	0.2	0.6	1.5	0.6	0.0	0.1	-0.2	2.1	-1.2	-1.1	0.3	-0.2	0.9	-0.8
Handedness (chirality/laterality): Left-handed	0.4	0.4	1.0	0.8	0.4	0.9	0.6	0.9	0.4	0.8	0.4	0.2	1.0	1.0	-0.2	1.0	0.9	-0.2	0.4	0.1	0.6
Illnesses of father: None of the above (group 1)	0.4	0.5	2.2	1.2	0.7	0.4	0.6	0.7	0.2	-0.0	0.2	0.9	-0.2	1.0	-0.2	0.2	0.5	1.5	1.1	0.4	0.7
Arm fat mass (left)	0.4	1.5	3.2	-1.8	-0.7	-1.7	-1.0	-1.8	-0.8	-1.0	-0.9	1.1	-1.2	-1.2	1.0	-1.8	-1.7	-0.1	-1.0	-0.6	-1.4
Number of self-reported non-cancer illnesses	0.4	0.7	2.2	0.7	1.0	0.0	0.5	-0.0	1.1	0.4	1.0	-1.1	0.1	0.5	1.5	0.2	0.3	1.1	0.5	1.0	1.5
High cholesterol (Self-reported)	0.4	0.8	4.5	0.3	0.2	0.7	0.7	0.8	0.9	0.4	0.9	-2.1	1.1	0.4	1.1	1.0	0.9	-0.7	0.5	0.8	0.4
Number of operations (self-reported)	0.4	0.5	2.4	-0.1	0.8	0.7	0.2	0.7	-0.6	0.7	-0.5	0.3	1.5	-1.2	-0.9	-0.0	0.0	-0.8	0.5	-0.2	-1.1
Age started oral contraceptive pill	0.4	0.5	3.0	-0.1	-1.0	0.1	-0.8	0.1	-0.5	-1.7	-0.3	-0.2	0.1	-0.8	0.1	0.9	1.0	-0.7	0.5	-0.6	0.4
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.6	-0.4	-0.6	-1.3	-1.1	-1.1	-0.9	0.3	-1.0	0.4	-0.6	-0.1	-1.1	0.1	0.0	-0.1	-0.5	-1.2	-0.1
Pack years of smoking	0.4	0.5	1.8	0.9	0.5	0.6	0.9	0.4	0.6	0.7	0.7	-0.4	-0.0	1.0	1.3	0.7	0.7	0.6	0.5	0.5	1.1
Intelligence (Savage-Jansen 2018)	0.3	1.0	4.9	1.2	1.0	0.7	1.2	0.3	0.7	2.2	0.6	0.4	1.1	1.6	0.2	-0.1	-0.2	1.6	1.1	1.0	-0.2
Worry (Nagel 2018)	0.3	0.7	3.2	-0.2	-1.3	-0.3	-0.8	0.2	0.6	-0.8	0.5	-1.8	0.1	0.0	0.5	1.0	1.0	-1.0	-0.4	-0.0	1.3
Alzheimer’s Disease (in father)	0.3	0.4	1.8	-0.7	0.4	0.4	0.2	0.4	0.3	0.5	0.3	-0.8	1.0	-0.5	0.8	-0.0	-0.0	-1.3	-0.8	0.3	-0.2
Age at First Birth	0.3	0.5	1.7	-0.3	-1.3	-1.3	-0.8	-0.9	-0.4	-0.7	-0.5	1.1	-0.6	0.7	-0.1	-0.4	-0.2	0.6	-0.7	-0.6	0.3
LDL Cholesterol	0.3	0.5	1.5	-0.1	-0.9	-0.8	-0.6	-0.9	-0.4	0.2	-0.4	1.0	-1.2	0.8	-0.0	-0.3	-0.3	1.1	-0.3	-0.2	0.8
Primary Biliary Cirrhosis	0.3	0.4	1.3	-0.7	0.9	0.7	0.6	0.6	0.3	0.4	0.1	-0.4	0.8	-1.2	0.6	-0.4	-0.6	-0.5	0.0	0.8	-1.0
Schizophrenia (2014)	0.3	0.6	1.7	-0.1	0.4	0.7	0.6	1.1	1.1	-0.4	1.1	-1.2	0.7	-0.0	1.3	0.3	0.3	0.0	0.5	1.1	0.6
Ulcerative Colitis	0.3	0.5	2.6	-0.5	0.5	-0.7	-0.1	-0.8	-0.5	-0.2	-0.5	0.2	-0.5	-0.2	-0.0	-1.3	-1.6	0.4	-0.8	-0.1	-1.3
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.3	-0.6	1.2	0.2	0.4	-0.1	-0.2	1.0	-0.2	0.7	0.3	-0.3	0.2	-1.2	-1.3	0.4	-0.2	0.5	-1.5
Systolic blood pressure, automated reading	0.3	1.0	5.8	-0.4	0.4	0.9	0.2	0.9	-0.4	0.8	-0.0	-1.0	2.0	-1.1	0.4	0.3	0.5	-2.4	-0.5	-0.2	-1.2
Hand grip strength (right)	0.3	0.9	3.5	-0.0	-1.6	-0.9	-0.7	-0.9	-0.7	-1.3	-0.7	1.5	-1.9	0.7	-1.4	0.2	-0.0	0.6	-0.4	-0.9	0.1
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.3	0.1	0.3	0.0	0.2	0.0	0.9	0.5	0.8	-1.1	0.7	0.1	0.8	0.8	0.7	0.1	0.7	0.2	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.1	-0.5	0.9	0.2	0.9	0.2	0.9	0.2	0.9	-0.7	1.4	-0.2	1.1	-0.9	-0.8	0.2	-0.4	1.2	-0.3
Serious illness, injury or assault to yourself	0.3	0.3	1.3	-0.3	1.1	0.6	0.4	0.6	0.1	1.1	0.2	-0.6	0.9	-0.5	0.4	0.2	0.3	-0.9	0.2	0.1	-0.5
High blood pressure	0.3	0.8	4.2	-1.2	0.4	-0.8	-0.4	-0.7	0.6	-0.8	0.6	-2.1	-0.8	-1.2	1.6	-0.5	-0.5	-0.5	-0.4	0.3	-0.1
Multivitamins +/- minerals	0.3	0.4	1.7	0.3	-0.4	-0.7	-0.4	-0.5	0.9	-1.3	0.7	-0.7	0.1	0.5	-0.2	0.1	0.4	0.4	-0.1	0.2	1.3
Number of incorrect matches in round	0.3	0.5	2.6	-0.1	-0.5	1.1	0.2	1.0	0.3	-0.3	0.4	-1.6	0.8	-0.6	-0.2	0.6	0.5	-1.0	0.4	0.5	-0.1
Had menopause	0.3	0.4	1.7	-0.5	-0.6	0.1	-0.5	0.1	-0.9	-0.5	-0.5	-0.4	0.4	-1.2	-0.2	0.1	0.2	-1.3	-0.2	-0.5	-0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.7	0.6	0.1	-0.8	-0.2	-0.6	0.3	1.3	0.1	0.1	-0.6	0.9	-0.0	-0.1	-0.1	1.2	0.2	-0.1	0.9
Heart attack	0.3	0.4	1.6	-0.4	-0.4	-1.3	-1.0	-1.0	-0.7	0.4	-0.8	0.3	-0.5	-0.0	-0.8	-0.1	-0.2	0.1	-0.5	-0.9	-0.2
Pain all over the body in last month	0.3	0.3	2.4	0.8	0.2	-0.4	-0.1	-0.3	0.1	1.0	0.1	0.3	-0.2	1.6	-0.2	0.3	0.2	0.6	-0.5	0.0	0.8
Medication: Simvastatin	0.3	0.4	3.0	-0.3	0.2	0.1	0.6	0.5	0.5	0.6	0.8	-1.7	0.0	-0.2	0.7	0.3	0.1	-0.1	-0.0	0.9	0.7
Number of live births	0.3	0.5	1.7	-0.6	0.5	-0.1	0.3	0.0	1.0	-0.3	0.8	-1.3	0.0	-0.9	0.9	-1.0	-0.8	0.1	-0.0	0.9	0.2
Pulse rate	0.3	0.4	2.9	1.1	0.7	-0.1	0.4	-0.4	0.1	-0.0	0.2	1.4	0.1	0.6	0.3	-0.2	-0.1	1.7	0.7	0.3	0.3
Prospective memory result	0.3	0.3	0.9	0.5	0.9	0.6	0.5	1.0	0.7	0.2	0.7	-0.3	0.2	0.1	0.5	0.1	0.3	0.6	0.9	0.6	0.2
Arm fat mass (right)	0.3	1.2	2.7	-1.6	-0.4	-1.5	-0.7	-1.5	-0.5	-0.8	-0.6	0.9	-1.0	-1.1	1.4	-1.6	-1.5	0.1	-0.8	-0.3	-1.2
High blood pressure (siblings)	0.3	0.4	1.5	0.3	-0.2	-0.1	-0.1	0.2	0.7	-0.4	0.8	0.2	0.8	1.2	0.9	0.6	0.7	0.8	0.5	0.5	0.8
Pulse wave peak to peak time	0.3	0.4	2.1	0.7	-0.5	0.5	0.2	0.4	-0.3	1.5	-0.4	0.4	-0.0	0.3	-0.6	0.9	0.9	0.3	1.1	-0.2	0.2
Health satisfaction	0.3	0.4	2.6	0.1	0.9	0.4	0.8	0.4	0.8	0.3	0.8	-0.7	1.0	0.0	1.6	-0.3	-0.2	-0.0	0.1	0.6	-0.1
Qualifications: College or University degree	0.3	1.0	3.1	-0.9	-0.3	-0.6	-0.9	-0.6	-1.0	-0.2	-1.1	0.6	-1.1	-1.3	-1.8	-0.3	-0.3	-1.5	-1.3	-1.3	-1.0
Hypertension (Self-reported)	0.3	0.8	3.2	-1.4	0.4	-0.9	-0.5	-0.8	0.5	-1.0	0.5	-1.8	-0.9	-1.3	1.5	-0.5	-0.5	-0.8	-0.6	0.1	-0.2
Diabetes diagnosed by doctor	0.3	0.6	1.7	-1.1	0.3	-0.5	-0.4	-0.6	-0.7	0.7	-0.7	0.3	-0.6	-1.0	0.0	-1.1	-1.3	-0.1	-0.8	-0.1	-1.3
Medication for cholesterol	0.3	0.5	1.5	0.3	0.7	0.6	0.9	0.6	0.9	-0.5	0.8	1.2	0.6	0.3	1.2	-0.3	-0.2	0.9	0.4	0.8	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.9	-0.1	0.4	-0.1	0.7	-0.1	0.6	0.8	0.4	0.6	-0.0	0.3	0.7	-0.9	-0.8	1.0	-0.3	0.8	0.1
Guilty feelings	0.3	0.5	1.6	-1.1	-0.5	-0.8	-0.8	-0.4	0.3	-0.9	0.1	-1.0	-0.6	-0.9	1.2	0.0	0.0	-1.0	-0.5	-0.0	0.0
Vascular/heart problems diagnosed by doctor	0.3	0.8	4.2	1.2	-0.7	0.7	0.2	0.6	-0.7	0.4	-0.7	2.1	0.7	0.9	-1.6	0.6	0.7	0.3	0.4	-0.6	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.4	-0.4	1.2	-0.4	0.3	-0.8	0.4	0.2	0.2	-0.4	-0.4	-0.6	0.9	-1.2	-1.2	0.6	-0.4	0.5	-0.1
Bipolar Disorder or Schizophrenia	0.2	0.5	1.4	0.7	0.8	0.5	0.8	0.7	0.8	0.8	0.8	0.7	0.3	1.0	0.4	0.2	0.2	1.2	0.7	0.9	0.5
Depression (Nagel 2018)	0.2	0.3	0.9	0.9	-0.9	0.5	-0.2	0.3	-0.5	-0.1	-0.3	0.4	0.2	0.6	-0.4	0.9	0.9	-0.1	0.5	-0.4	0.2
Mean Putamen Volume	0.2	0.2	0.8	-0.3	0.0	0.1	0.4	-0.1	0.0	0.5	0.0	0.7	0.9	-0.5	-0.0	-0.9	-0.8	0.5	-0.2	0.6	-0.1
HbA1C	0.2	0.2	0.7	-0.5	-0.6	-0.7	-0.6	-0.7	-0.2	-0.7	-0.2	0.2	-0.8	0.1	-0.1	-0.1	-0.1	-0.2	-0.2	-0.6	-0.7
Blood White Count	0.2	1.2	3.7	-1.9	-0.9	-1.8	-1.2	-1.4	-0.4	-1.0	-0.6	0.5	-1.5	-0.6	0.4	-1.1	-0.9	-0.6	-1.5	-0.6	-0.4
Heel T-Score	0.2	1.9	6.7	-0.8	2.4	0.9	1.6	1.1	1.5	0.9	1.5	-0.9	1.6	0.1	2.6	-1.4	-1.2	0.1	-0.1	2.0	-0.8
Cardiovascular Disease	0.2	0.5	4.6	-0.6	0.7	-0.1	0.1	-0.0	0.8	-0.2	0.8	-2.1	-0.3	-0.2	1.3	0.3	0.2	-0.4	0.0	0.5	0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.3	2.3	-0.1	0.1	-0.4	-0.1	-0.4	-0.2	1.5	-0.1	-0.6	-0.6	-0.8	-0.1	-0.4	-0.6	0.6	0.4	0.1	-0.4
Severe depression (siblings)	0.2	0.2	1.0	0.2	-0.8	-0.3	-0.1	-0.2	0.2	-0.4	0.1	-1.0	-0.6	-0.1	0.5	-0.5	-0.3	0.4	-0.1	0.5	0.6
Trunk fat percentage	0.2	0.8	2.5	-1.4	-0.4	-1.2	-0.5	-0.9	0.1	-1.4	0.1	-0.6	-0.2	-1.2	1.6	-1.3	-1.1	-0.3	-0.8	0.2	-0.5
Current tobacco smoking	0.2	0.3	1.3	-0.5	-0.7	-0.4	-0.6	-0.2	-0.5	-0.6	-0.4	0.5	-1.1	-0.0	0.6	-0.2	-0.0	-1.0	-0.9	-0.7	-0.1
Age when periods started (menarche)	0.2	0.6	2.9	-0.5	0.6	-0.1	0.1	0.0	-0.8	0.1	-0.7	1.0	-0.6	-0.6	0.6	-1.4	-1.4	0.1	-0.3	-0.2	-1.7
Qualifications: CSEs or equivalent	0.2	0.3	1.3	0.1	-0.7	0.5	0.2	0.7	0.4	-0.5	0.5	-0.3	1.1	0.6	0.8	0.6	0.7	-0.4	0.1	0.4	0.4
Past tobacco smoking	0.2	0.3	0.9	0.3	0.8	0.1	0.7	0.1	0.4	0.2	0.4	0.4	0.8	0.9	0.4	-0.1	-0.1	0.7	-0.2	0.9	0.9
Allergy	0.2	0.4	1.5	-0.1	-1.1	0.1	-0.6	0.2	-1.0	-0.4	-0.6	0.7	-0.2	-0.0	-1.2	0.4	0.3	-1.0	-0.2	-0.9	-0.5
Illnesses of siblings	0.2	0.3	1.0	0.7	0.6	0.8	1.0	0.5	0.4	0.9	0.2	0.7	0.4	0.7	-0.0	0.2	0.1	0.4	0.4	0.3	-0.1
Arm fat percentage (right)	0.2	0.9	6.7	-1.3	0.8	-0.4	0.5	-0.4	0.7	-0.4	0.7	-0.6	0.5	-0.9	2.6	-1.4	-1.2	0.1	-0.2	1.1	-0.7
Time employed in main current job	0.2	0.3	1.5	-0.0	-0.5	-0.4	-0.3	-0.4	-0.3	0.9	-0.4	-1.2	0.3	-0.2	-0.6	-0.4	-0.4	-0.1	-0.3	-0.2	-0.5
Father’s age at death	0.2	0.2	0.7	0.2	-0.3	-0.1	-0.3	-0.1	0.5	-0.8	0.3	-0.4	-0.7	-0.1	-0.7	0.4	0.6	-0.3	-0.1	-0.3	0.8
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.5	0.4	-0.9	-0.4	-0.4	-0.3	-0.6	-1.0	-0.4	-0.5	0.2	0.5	-1.0	1.2	1.1	-0.5	-0.3	-0.6	1.0
Asthma	0.2	0.4	1.9	0.8	0.6	-0.0	0.4	-0.0	0.6	0.6	0.4	0.5	0.5	0.6	0.9	-0.1	0.0	1.4	0.4	0.7	0.9
Medication: Cholesterol lowering	0.2	0.4	1.3	-0.1	-1.1	-0.2	-0.3	0.2	0.2	-0.7	0.2	-0.9	0.1	-0.3	0.2	1.1	1.0	-0.2	0.4	0.0	1.0
Lung cancer (father)	0.2	0.3	0.9	0.9	0.3	0.6	0.1	0.5	-0.8	-0.6	-0.7	0.9	0.2	0.6	-0.5	0.3	0.5	-0.2	0.2	-0.4	-0.3
Breastfed as a baby	0.2	0.2	1.2	0.0	0.5	-0.2	0.2	0.4	0.6	1.0	0.4	-1.1	-0.3	-0.2	0.0	0.3	0.4	-0.0	-0.0	0.3	0.6
Pulse wave reflection index	0.2	0.3	1.1	0.4	1.1	0.5	0.7	0.6	0.5	0.1	0.5	-0.1	0.3	0.7	0.4	0.2	-0.0	0.5	0.2	0.7	0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.7	0.2	0.5	0.2	0.6	0.5	0.6	-0.4	0.5	-0.2	0.1	0.8	0.0	-0.4	-0.1	0.3	-0.4	0.6	0.8
Gout (self-reported)	0.2	0.3	1.9	0.1	-0.1	-0.0	-0.0	-0.5	-0.9	1.4	-0.6	1.1	-0.5	-0.3	-0.5	-0.1	-0.4	0.6	0.3	-0.1	-0.6
Body fat percentage	0.2	0.7	3.6	-1.4	-0.1	-0.9	-0.2	-0.7	0.3	-1.1	0.3	-0.7	0.0	-1.1	1.9	-1.3	-1.1	-0.2	-0.5	0.4	-0.6
Leg fat percentage (right)	0.2	0.7	4.9	-0.8	0.6	-0.0	0.4	0.1	0.7	-0.2	0.7	-1.4	0.7	-0.6	2.2	-0.6	-0.5	-0.4	-0.0	0.9	-0.3
Comparative body size at age 10	0.2	0.6	3.5	-0.3	1.9	0.7	0.7	0.3	-0.1	1.1	-0.2	0.4	0.9	0.5	0.1	-0.2	-0.6	0.0	0.6	0.4	-1.5
Number of full brothers	0.2	0.3	0.6	0.8	-0.2	-0.3	-0.6	-0.4	-0.5	-0.3	-0.4	0.3	-0.5	0.6	-0.6	0.7	0.8	0.6	0.5	-0.7	0.7
Medication for pain relief, constipation, heartburn	0.2	0.3	1.2	0.4	-0.1	0.6	0.3	0.7	-0.8	-0.9	-0.3	1.1	0.4	-0.6	-0.7	0.2	0.1	0.3	0.4	0.0	-0.6
Pulse rate, automated reading	0.2	0.7	6.3	0.0	0.6	-0.2	0.2	-0.5	-0.9	0.5	-0.7	2.5	-0.2	0.5	-0.1	-1.0	-0.8	0.9	-0.3	-0.3	-0.8
Had major operations	0.2	0.3	1.4	-0.1	0.8	0.3	0.3	0.5	0.1	0.5	0.1	1.2	0.7	-0.7	-0.6	-0.2	-0.1	0.2	0.3	0.2	-0.6
Age at last live birth	0.2	0.3	1.6	0.8	-0.7	0.5	0.2	0.6	-0.5	0.3	-0.4	1.0	0.1	0.3	-1.3	0.2	0.2	0.2	0.3	-0.2	0.1
Illnesses of father: Heart disease	0.2	0.3	1.1	-0.6	-0.7	-0.1	-0.4	0.0	-0.4	0.5	-0.2	-0.6	0.7	-1.0	-0.2	-0.2	-0.3	-1.0	-0.5	-0.1	-0.7
Smoking status: Previous	0.2	0.2	0.8	0.0	-0.9	-0.0	-0.5	0.1	-0.0	-0.4	-0.2	-0.7	-0.3	-0.6	-0.9	0.4	0.4	-0.4	0.4	-0.7	-0.5
Arm fat percentage (left)	0.2	0.8	5.3	-1.3	0.5	-0.6	0.2	-0.6	0.5	-0.5	0.4	-0.2	0.3	-0.8	2.3	-1.4	-1.2	0.2	-0.2	0.8	-0.7
Ever had bowel cancer screening	0.2	0.2	0.6	-0.4	-0.1	-0.7	-0.7	-0.8	-0.2	-0.3	-0.4	0.0	-0.5	-0.5	-0.5	-0.8	-0.8	0.2	-0.3	-0.3	-0.1
Breast cancer (self-reported)	0.2	0.3	1.4	0.5	0.0	0.0	-0.4	-0.3	-0.1	-0.7	-0.1	-0.1	0.2	0.3	-0.6	1.2	1.1	-0.3	0.3	-0.9	0.4
Average weekly champagne plus white wine intake	0.2	0.3	1.2	-0.7	0.6	-0.1	0.2	0.3	0.4	-1.1	0.3	-0.1	-1.0	-0.9	-0.0	-0.2	-0.3	0.1	0.4	0.3	-0.4
Medication: Blood pressure	0.2	0.4	2.1	0.1	1.1	0.4	0.4	0.2	0.6	0.9	0.6	-1.4	-0.1	0.1	0.8	0.1	-0.0	-0.1	0.4	0.6	0.0
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.3	0.7	-0.1	-0.3	-0.2	-0.3	-0.3	0.4	-0.2	0.0	-0.2	0.5	-0.6	0.6	0.6	0.6	0.4	-0.6	1.1
Medication: Lisinopril	0.2	0.3	0.7	-0.3	-0.8	-0.8	-0.6	-0.4	-0.4	-0.8	-0.2	-0.5	0.0	-0.1	0.3	0.6	0.6	-0.0	-0.1	-0.5	0.8
Alcohol drinker status: Never	0.2	0.3	0.9	0.4	0.1	0.4	-0.3	0.4	-0.4	-0.1	-0.3	-0.3	0.6	-0.2	-1.0	0.9	0.7	-0.7	0.2	-0.5	-0.3
Leg fat percentage (left)	0.2	0.7	4.9	-1.1	0.6	-0.1	0.4	-0.0	0.6	-0.0	0.6	-1.4	0.7	-0.8	2.2	-0.8	-0.7	-0.5	-0.1	0.9	-0.6
Ever depressed for a whole week	0.2	0.3	2.1	0.6	0.8	0.3	0.5	0.4	0.2	1.5	0.2	0.1	0.4	0.7	-0.4	0.2	0.2	0.1	0.2	0.1	0.4
Cholesterol lowering medication	0.2	0.2	1.4	0.2	-0.2	0.2	-0.1	-0.0	-0.1	0.6	0.1	-1.2	0.4	0.5	0.2	0.9	0.7	-0.1	0.6	0.1	0.4
Schizophrenia (2018)	0.1	0.2	1.0	-0.4	-0.2	0.4	0.2	0.5	0.5	0.1	0.6	-1.0	0.5	0.1	0.7	0.1	0.0	-0.0	0.2	0.7	0.5
Blood Platelet Count	0.1	1.3	12.7	-0.7	0.0	-0.5	-0.6	-0.3	1.1	-1.3	1.0	-3.6	0.0	-0.1	0.7	0.7	0.8	-1.6	-0.5	-0.2	0.7
BMI	0.1	0.6	2.2	-1.4	0.3	-0.8	-0.3	-0.8	-0.4	0.1	-0.5	0.3	-0.1	-1.2	0.6	-0.9	-1.0	-0.4	-0.3	-0.2	-1.5
Systolic Blood Pressure	0.1	0.7	4.1	-0.3	0.6	0.5	0.3	0.6	0.6	0.4	0.8	-2.0	1.0	-0.5	0.2	0.4	0.6	-1.9	-0.6	0.2	-0.1
Smoking Status	0.1	0.1	0.8	0.2	-0.5	0.1	-0.4	0.2	-0.3	0.3	-0.3	0.1	-0.9	0.1	0.0	0.0	0.2	-0.4	0.2	-0.6	-0.4
Tanning	0.1	0.6	2.6	-0.2	-0.7	-0.8	-1.1	-0.7	-0.7	-1.2	-0.8	0.2	-0.9	-0.3	-1.6	-0.2	-0.2	-0.4	-0.8	-1.3	0.2
Relative age of first facial hair	0.1	0.3	1.0	0.8	-0.3	0.7	0.3	0.6	0.6	0.1	0.6	-0.6	1.0	0.1	0.2	0.4	0.5	0.3	0.5	0.3	0.5
Supplements: Zinc	0.1	0.1	1.2	-0.2	0.4	-0.3	-0.2	-0.5	0.1	1.1	-0.1	-0.0	-0.3	0.3	-0.1	-0.1	-0.3	-0.1	-0.6	-0.1	-0.1
Medication: Co-codamol	0.1	0.2	1.0	0.1	0.1	-0.4	-0.1	0.1	0.2	0.3	0.3	-0.3	-0.9	0.3	1.0	-0.0	-0.1	0.7	0.3	0.1	0.2
Maternal smoking around birth	0.1	0.2	1.4	-0.2	0.5	0.1	0.3	0.1	-0.3	1.2	-0.2	0.6	0.2	0.5	0.6	-0.0	-0.1	0.3	0.0	0.2	-0.2
Taking other prescription medications	0.1	0.1	0.6	0.0	-0.4	-0.5	-0.5	-0.5	0.0	-0.2	-0.0	-0.4	-0.1	-0.2	0.8	0.5	0.5	0.0	0.1	-0.3	0.5
Chronic bronchitis/emphysema (father)	0.1	0.2	0.5	-0.5	-0.3	-0.3	-0.3	-0.4	-0.2	-0.7	-0.2	-0.5	-0.0	-0.4	0.3	-0.5	-0.4	-0.6	-0.6	-0.3	-0.2
Hair/balding pattern: Pattern 4	0.1	0.3	1.3	-0.1	0.4	-0.2	-0.3	0.1	-0.5	0.0	-0.5	0.6	-0.2	-0.4	-1.1	-0.5	-0.3	-0.9	-0.7	-0.8	-0.7
Emphysema/chronic bronchitis	0.1	0.1	0.8	0.3	-0.2	0.2	0.0	0.1	0.2	-0.0	0.2	-0.5	0.9	0.4	0.4	0.1	0.2	-0.1	0.3	0.1	0.1
Asthma (self-reported)	0.1	0.3	1.3	0.6	0.2	-0.2	0.2	-0.1	0.6	0.4	0.4	0.3	0.3	0.6	0.6	-0.1	0.1	1.1	0.2	0.5	0.9
Smoking status: Current	0.1	0.2	0.8	-0.2	-0.1	0.1	-0.2	0.2	-0.3	-0.3	-0.2	0.4	-0.8	0.2	0.7	0.0	0.2	-0.9	-0.4	-0.4	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.5	0.3	0.6	0.1	0.1	0.1	0.3	-0.3	0.3	-1.2	-0.4	0.5	-0.3	0.6	0.4	-0.1	0.1	-0.0	0.8
Diastolic blood pressure, automated reading	0.1	0.4	2.9	-0.7	0.6	-0.1	-0.2	-0.2	0.1	0.2	0.3	-0.3	0.4	-1.0	0.6	-0.0	0.3	-1.7	-0.9	-0.5	-0.5
Heart disease (siblings)	0.1	0.2	1.4	0.1	1.2	-0.0	0.1	-0.0	0.1	-0.1	0.3	-0.6	-0.3	-0.5	0.3	0.1	0.1	0.3	0.5	0.4	0.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.4	3.9	-0.5	0.4	0.1	-0.0	-0.1	-1.1	-0.3	-0.7	2.0	-0.3	-0.7	-0.3	0.0	0.1	-0.4	0.0	-0.4	-0.6
Respiratory disease	0.0	0.1	0.4	0.2	0.7	-0.1	0.1	-0.1	0.4	-0.2	0.4	0.1	0.2	0.2	0.6	0.1	0.1	0.5	0.0	0.4	0.3
Hair Pigment	0.0	0.6	1.6	0.1	-0.9	-0.3	-1.0	-0.1	-1.0	-1.2	-0.7	-0.0	-0.8	-0.0	-0.3	1.1	1.3	-0.4	0.3	-1.3	0.7
Commuting to job workplace: Public transport	0.0	0.0	0.2	0.3	0.1	-0.1	-0.2	-0.3	-0.1	-0.1	-0.1	0.1	-0.3	0.1	-0.2	0.3	0.4	-0.0	0.0	-0.4	0.1

Hub : Genes

GNPTAB

Models

Trait associations