[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr12:94,772,262-97,056,904

Best TWAS P=1.4e-28 · Best GWAS P=1.05e-60 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CCDC38	0.13	0.02	blup	123	0.05	2.1e-03	5.5	11.1	1.4e-28	0.64	0.06	0.16	TRUE
2	GTEx	Artery Aorta	FGD6	0.19	0.19	lasso	6	0.19	6.2e-11	8.0	-10.0	1.6e-23	-0.05	1.00	0.00	TRUE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	NTN4	0.04	0.02	blup	135	0.00	9.0e-02	6.6	-7.1	1.1e-12	-0.08	0.39	0.03	TRUE
10	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	AMDHD1	0.10	0.12	blup	93	0.06	1.5e-04	-3.4	5.7	1.1e-08	0.13	0.03	0.96	TRUE
12	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	AMDHD1	0.08	0.04	blup	93	0.02	4.4e-02	5.5	5.7	1.3e-08	0.41	0.05	0.03	TRUE
8	The Cancer Genome Atlas	Glioblastoma Multiforme	LTA4H	0.21	0.00	enet	11	0.00	3.0e-01	1.4	5.6	1.8e-08	0.02	0.03	0.26	TRUE
15	The Cancer Genome Atlas	Thyroid Carcinoma	SNRPF	0.09	0.02	lasso	2	0.01	8.4e-02	2.0	5.6	1.9e-08	0.11	0.01	0.04	TRUE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SNRPF	0.24	0.05	enet	10	0.08	3.6e-05	2.0	8.9	4.5e-19	0.17	0.09	0.05	FALSE
4	GTEx	Artery Tibial	FGD6	0.17	0.09	lasso	9	0.09	7.1e-08	8.0	-8.6	7.8e-18	-0.03	1.00	0.00	FALSE
5	GTEx	Cells Transformed fibroblasts	FGD6	0.19	0.22	lasso	5	0.20	2.4e-15	7.1	-7.3	2.6e-13	-0.01	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AMDHD1	0.13	0.06	bslmm	546	0.09	8.9e-11	-3.4	6.5	6.1e-11	0.36	1.00	0.00	FALSE
3	GTEx	Artery Tibial	AMDHD1	0.31	0.15	enet	10	0.26	4.3e-20	5.0	6.4	2.0e-10	0.27	1.00	0.00	FALSE
7	YFS	Blood	METAP2	0.07	0.05	enet	33	0.06	5.5e-18	-1.3	-5.6	2.3e-08	-0.12	1.00	0.00	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NTN4	0.07	0.05	enet	10	0.05	2.5e-06	-5.8	5.6	2.3e-08	0.02	0.97	0.00	FALSE
6	GTEx	Esophagus Muscularis	AMDHD1	0.33	0.23	enet	25	0.25	2.5e-15	-3.2	5.2	2.0e-07	0.26	1.00	0.00	FALSE