Best TWAS P=4.59e-09 · Best GWAS P=4.89e-11 conditioned to 0.000793
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | NID2 | 0.10 | 0.08 | lasso | 5 | 0.07 | 3.5e-06 | -5.9 | 5.2 | 1.7e-07 | -0.74 | 0.11 | 0.85 | FALSE |
| 2 | GTEx | Testis | NID2 | 0.28 | 0.13 | lasso | 5 | 0.10 | 5.2e-05 | 5.6 | 5.9 | 4.6e-09 | -0.73 | 0.05 | 0.91 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C14orf166 | 0.06 | 0.04 | lasso | 4 | 0.04 | 2.3e-05 | -5.5 | 5.2 | 2.3e-07 | -0.73 | 0.07 | 0.86 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C14orf166 | 0.08 | 0.04 | lasso | 2 | 0.05 | 3.4e-04 | -5.6 | 5.4 | 5.7e-08 | -0.78 | 0.05 | 0.61 | FALSE |