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Lung FEV1/FVC ratio
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chr14:53,731,553-55,118,795
Best TWAS P=1.38e-36 · Best GWAS P=1.87e-30 conditioned to 0.000754
53.8M
54M
54.2M
54.4M
54.6M
54.8M
55M
55.2M
0
5
10
15
20
25
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Brain Cerebellum
BMP4
0.34
0.13
enet
21
0.16
1.7e-05
10
12.6
1.4e-36
-0.72
0.08
0.77
TRUE
1
CommonMind
Brain Pre-frontal Cortex
BMP4
0.09
0.09
enet
6
0.09
8.5e-11
10
9.3
1.3e-20
-0.55
0.99
0.01
FALSE