TWAS hub - BMP4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.095	0.03	6.1e-05	0.092	0.034	0.087	0.079	0.086	2.8e-11	4.3e-05	8.5e-11	7e-10	1.1e-10
2	GTEx	Brain Cerebellum	0.339	0.11	4.0e-03	0.134	NA	0.161	NA	0.116	9.1e-05	NA	1.8e-05	NA	2.7e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Heel T-Score	86.3	686.5	772.8	-24.5	-27.8
Heel bone mineral density (BMD) T-score, automated (left)	56.9	129.1	141.6	-10.8	-11.9
Heel bone mineral density (BMD) T-score, automated (right)	56.1	128.5	148.8	-10.4	-12.2
Lung FEV1/FVC ratio	24.3	123.2	159.6	9.3	12.6
Myopia	12.4	18.1	25.1	-3.3	-5.0
Bipolar Disorder (2011)	10.5	10.2	12.1	-3.5	-2.9
Number of operations (self-reported)	9.4	14.0	15.2	-3.6	-3.9
Eye problems/disorders: None of the above	9.2	10.7	11.6	3.1	3.4
Had major operations	7.4	8.7	9.5	-3.1	-2.8
Peak expiratory flow (PEF)	6.9	16.1	24.1	2.8	4.9
Illness, injury, bereavement, stress in last 2 years	6.5	8.0	8.8	3.0	2.7
Eye problems/disorders: Cataract	5.7	6.6	6.7	-2.6	-2.6
Loneliness, isolation	5.5	7.6	11.0	-2.1	-3.3
Medication for cholesterol	5.5	8.4	8.8	2.8	3.0
Allergy	5.4	12.4	13.0	3.4	3.6
Back pain experienced in last month	5.3	7.7	10.9	2.1	3.3
Ulcerative Colitis	4.9	7.2	10.0	-3.2	-2.1
Hayfever, allergic rhinitis or eczema	4.9	10.6	11.2	-3.3	-3.2
Lung FVC	4.8	24.4	26.7	-4.7	-5.2
Mouth/teeth dental problems: Bleeding gums	4.8	6.2	6.7	-2.4	-2.6
Medication for hormone replacement therapy	4.7	5.3	5.8	-2.2	-2.4
Pulse wave peak to peak time	4.4	5.1	6.2	2.5	2.0
Frequency of depressed mood in last 2 weeks	4.3	6.0	9.9	-1.4	-3.1
Number of full brothers	4.3	5.4	6.1	-2.2	-2.5
Systolic Blood Pressure	4.2	21.1	23.5	-4.3	-4.8
Diastolic blood pressure, automated reading	4.1	12.6	13.9	-3.4	-3.7
Asthma (self-reported)	4.0	8.0	8.4	-2.8	-2.9
Medication: Lisinopril	4.0	5.2	6.9	-2.6	-1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.9	4.6	5.7	1.9	2.4
Tinnitus: Yes, now most or all of the time	3.8	4.4	6.8	1.4	2.6
Type 2 Diabetes (T2D) (2012)	3.7	4.3	4.7	-2.0	-2.2
Systolic blood pressure, automated reading	3.7	10.6	13.6	-2.8	-3.7
Medication: Allopurinol	3.7	5.0	7.1	2.7	1.7
Medication: Ventolin 100micrograms inhaler	3.6	4.6	6.7	-1.6	-2.6
Ulcerative Colitis (UC)	3.5	6.6	7.5	-2.7	-2.4
Bilateral oophorectomy (both ovaries removed)	3.5	4.1	4.5	-1.9	-2.1
Shortness of breath walking on level ground	3.5	4.2	5.5	-1.7	-2.4
Pack years of smoking	3.5	5.1	5.9	-2.4	-2.1
Allergy or Eczema	3.4	9.1	9.1	-3.0	-3.0
Asthma	3.4	6.8	7.1	-2.5	-2.7
Medication: Lansoprazole	3.4	3.9	5.7	-1.4	-2.4
Medication: Bendroflumethiazide	3.4	5.1	5.4	-2.3	-2.2
Age at First Birth	3.2	4.7	5.8	2.4	1.9
Diabetes (mother)	3.2	4.1	6.1	-1.5	-2.5
Medication: Seretide 50 evohaler	3.2	3.7	4.5	-2.1	-1.7
Respiratory disease	3.1	6.9	7.3	-2.5	-2.7
Pulse wave Arterial Stiffness index	3.1	3.6	4.5	-2.1	-1.6
Alzheimer’s Disease (in father)	2.9	3.1	5.5	-0.9	-2.3
Hayfever/allergic rhinitis (self-reported)	2.9	3.8	4.1	-2.0	-1.9
Birth weight of first child	2.8	5.1	5.5	-2.3	-2.2
Depression (Nagel 2018)	2.7	4.1	6.6	-1.3	-2.6
Gout (self-reported)	2.7	3.8	5.7	2.4	1.3
Falls in the last year	2.6	3.5	4.0	-1.7	-2.0
Hypothyroidism/myxoedema (self-reported)	2.6	5.1	7.3	-1.7	-2.7
Medication: Blood pressure	2.6	4.7	4.8	-2.2	-2.1
Hypothyroidism (self reported)	2.5	5.6	7.6	-1.9	-2.8
Medication: Paracetamol	2.3	3.8	4.4	-1.8	-2.1
Mood swings	2.3	4.1	5.0	-1.8	-2.2
Pack years adult smoking proportion	2.2	3.3	4.3	-2.1	-1.5
High blood pressure	2.2	6.1	6.3	-2.4	-2.5
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.9	3.2	-1.6	-1.8
Financial difficulties in last 2 years	2.0	2.6	3.6	-1.9	-1.3
Father’s age at death	2.0	2.7	3.5	1.9	1.4
Number of children fathered	2.0	2.2	3.0	1.2	1.7
Migraine (self-reported)	2.0	2.5	2.9	1.7	1.4
Number of treatments/medications taken	1.9	3.4	5.4	-1.2	-2.3
Hypertension (Self-reported)	1.9	5.3	5.5	-2.4	-2.2
Number of self-reported non-cancer illnesses	1.9	3.3	5.4	-1.1	-2.3
Impedance of whole body	1.9	9.8	11.4	3.4	2.9
Chronotype (morning person)	1.8	4.1	5.1	1.8	2.3
Had menopause	1.8	2.2	2.8	1.7	1.3
Number of live births	1.8	2.6	2.8	1.5	1.7
Long-standing illness, disability or infirmity	1.8	2.7	3.9	-1.3	-2.0
Unable to work because of sickness or disability	1.8	2.3	2.3	-1.5	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	4.4	-0.5	-2.1
Prospective memory result	1.7	2.1	3.5	-1.9	-0.9
Worry too long after embarrassment	1.7	2.9	3.8	1.9	1.4
Pulse rate, automated reading	1.7	5.6	8.2	2.9	1.7
Alcohol drinker status: Never	1.7	2.0	2.0	1.4	1.4
Medication: Omeprazole (e.g. Zanprol)	1.7	2.0	2.9	-1.1	-1.7
Taking other prescription medications	1.6	2.5	4.2	-0.9	-2.0
Sitting height	1.6	11.1	12.6	3.5	3.1
Waist circumference	1.6	5.9	8.9	-1.7	-3.0
Noisy workplace	1.6	1.9	3.2	-0.8	-1.8
Impedance of arm (left)	1.6	7.6	11.8	3.4	1.8
Forced vital capacity (FVC), Best measure	1.6	5.7	6.0	-2.3	-2.5
Exposure to tobacco smoke outside home	1.6	2.1	2.4	-1.5	-1.3
Fractured/broken bones in last 5 years	1.6	2.0	2.3	1.3	1.5
Vascular/heart problems diagnosed by doctor	1.6	4.5	5.0	2.0	2.2
Waist Hip Ratio (WHR)	1.5	6.7	6.7	-2.6	-2.6
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.5	3.4	-1.2	-1.8
Hair/balding pattern: Pattern 3	1.5	2.3	3.5	1.0	1.9
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	1.8	1.4	1.3
Medication: Paracetamol	1.5	2.3	2.3	-1.5	-1.5
Irritable Bowel Disease (IBD)	1.4	3.3	4.4	-2.1	-1.5
Primary Biliary Cirrhosis	1.4	1.9	3.7	0.4	1.9
Supplements: Zinc	1.4	1.5	2.1	-1.4	-1.0
Mouth/teeth dental problems	1.4	2.2	2.2	1.5	1.5
Health satisfaction	1.4	1.8	2.4	-1.1	-1.6
Friendships satisfaction	1.4	1.7	2.1	-1.4	-1.2
Qualifications: nursing, teaching	1.4	2.2	2.4	1.4	1.6
LDL Cholesterol	1.3	2.1	2.3	1.5	1.4
Ever highly irritable/argumentative for 2 days	1.3	1.5	2.4	-1.5	-0.8
Number of full sisters	1.3	1.6	2.6	1.6	0.7
Medication: Blood pressure	1.3	2.4	2.5	-1.5	-1.6
Triglycerides	1.2	2.0	2.5	1.2	1.6
Diabetes (father)	1.2	1.5	1.6	-1.2	-1.3
Had other major operations	1.2	1.5	2.4	-0.7	-1.5
Diabetes (self-reported)	1.2	1.9	3.2	-0.7	-1.8
Qualifications: A levels/AS levels or equivalent	1.2	2.6	3.9	2.0	1.1
Cardiovascular Disease	1.1	3.7	4.8	-1.6	-2.2
Medication: Metformin	1.1	1.5	2.7	-0.6	-1.7
Hair/balding pattern: Pattern 2	1.1	1.4	2.4	1.6	0.7
Forced vital capacity (FVC)	1.1	4.2	4.2	-2.0	-2.1
Impedance of arm (right)	1.1	5.0	8.4	2.9	1.3
Medication: Cholesterol lowering	1.1	1.7	2.0	1.4	1.2
Length of working week for main job	1.1	1.2	1.7	-1.3	-0.8
Depressed Affect (Nagel 2018)	1.0	2.1	2.8	-1.2	-1.7
Height	1.0	18.5	23.5	4.8	3.7
Relative age of first facial hair	1.0	2.2	2.3	1.4	1.5
Diverticular disease/diverticulitis (self-reported)	1.0	1.1	1.4	1.2	0.9
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	1.7	-1.3	-0.8
Emphysema/chronic bronchitis	1.0	1.2	1.2	-1.1	-1.1
Diabetes diagnosed by doctor	1.0	1.7	2.9	-0.7	-1.7
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	1.7	-1.2	-1.3
Breast cancer (self-reported)	1.0	1.2	2.0	-0.6	-1.4
Average weekly champagne plus white wine intake	1.0	1.4	1.6	1.1	1.3
Bipolar Disorder (2018)	0.9	1.5	1.9	-1.4	-1.1
Coronary Artery Disease (CAD)	0.9	1.1	1.3	-1.1	-0.9
HDL Cholesterol	0.9	1.5	2.0	-1.0	-1.4
Townsend deprivation index at recruitment	0.9	1.3	2.1	-0.7	-1.5
Average weekly fortified wine intake	0.9	1.0	1.3	0.9	1.1
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	1.0	-0.9	-1.0
Impedance of leg (left)	0.9	4.2	5.8	1.6	2.4
High blood pressure (siblings)	0.9	1.3	2.0	-0.8	-1.4
Family relationship satisfaction	0.9	1.1	1.9	-1.4	-0.4
Leg pain on walking	0.9	1.2	1.8	-0.7	-1.3
Commuting to job workplace: Car/motor vehicle	0.9	1.1	1.3	-1.1	-0.9
Basal cell carcinoma (self-reported)	0.9	1.0	1.3	-0.8	-1.2
Severe depression (siblings)	0.8	0.9	1.7	-0.3	-1.3
Impedance of leg (right)	0.8	3.7	5.5	1.3	2.4
Fed-up feelings	0.8	1.5	2.7	-0.6	-1.6
Qualifications: CSEs or equivalent	0.8	1.1	1.4	-0.9	-1.2
Medication: Levothyroxine sodium	0.8	1.4	2.3	-0.6	-1.5
Illnesses of mother	0.8	1.0	1.7	0.6	1.3
Standing height	0.8	7.7	7.8	2.8	2.7
Smoking status: Previous	0.8	1.1	1.2	1.1	1.0
Medication: Aspirin	0.8	1.1	1.3	0.9	1.1
Illnesses of father: None of the above (group 1)	0.8	1.0	2.0	1.4	0.3
Medication: Atorvastatin	0.8	1.0	1.5	0.6	1.2
Worry (Nagel 2018)	0.7	1.5	2.3	-0.8	-1.5
Ovarian Cancer	0.7	0.9	1.2	-1.1	-0.8
Crohns Disease (2012)	0.7	1.2	2.1	-1.5	-0.5
Lupus	0.7	1.1	1.5	-0.8	-1.2
Hand grip strength (right)	0.7	1.9	3.8	0.3	1.9
Multivitamins +/- minerals	0.7	0.8	1.0	-0.8	-1.0
Hair/balding pattern: Pattern 4	0.7	1.8	2.1	1.2	1.4
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	1.6	0.8	1.3
Age at first live birth	0.7	1.2	1.3	1.1	1.0
Illnesses of siblings: Diabetes	0.7	0.9	1.7	0.2	-1.3
Age started oral contraceptive pill	0.7	0.9	1.8	1.4	0.1
Neuroticism (2016)	0.6	0.9	1.4	-0.6	-1.2
Hand grip strength (left)	0.6	1.5	2.6	0.5	1.6
Body mass index (BMI)	0.6	2.7	3.9	-1.2	-2.0
Illnesses of siblings	0.6	0.9	1.3	0.6	1.1
Mouth/teeth dental problems: Dentures	0.6	1.0	1.1	0.9	1.1
Wheeze or whistling in the chest in last year	0.6	1.1	1.9	-0.5	-1.4
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.3	0.3	1.1
Medication: Omeprazole	0.6	0.7	1.1	-0.6	-1.1
Chest pain or discomfort	0.6	0.9	1.0	-0.9	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	1.6	-1.0	-1.3
Ever had bowel cancer screening	0.6	0.7	1.4	0.2	-1.2
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.4	0.4	1.2
Alcohol drinker status: Previous	0.6	0.7	1.2	1.1	0.5
Bipolar Disorder or Schizophrenia	0.5	1.3	1.6	-1.3	-1.0
Schizophrenia vs Biploar Disorder	0.5	0.7	1.4	1.2	0.2
HbA1C	0.5	0.6	0.9	0.9	0.5
Rheumatoid Arthritis	0.5	0.7	0.8	-0.7	-0.9
Hearing difficulty/problems: Yes	0.5	0.8	1.3	-0.5	-1.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.3	-0.1	-1.2
Relative age voice broke	0.5	0.8	1.2	0.7	1.1
Stomach or abdominal pain in last month	0.5	0.6	1.2	-0.0	-1.1
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	0.7	0.8	0.7
Hip circumference	0.5	2.3	4.4	-0.4	-2.1
Alcohol intake versus 10 years previously	0.5	0.8	1.4	-0.3	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	2.5	0.8	1.6
Pulse wave reflection index	0.5	0.6	1.2	-1.1	-0.0
Qualifications: College or University degree	0.5	1.4	2.0	0.9	1.4
Medication: Ibuprofen	0.5	0.6	1.1	0.4	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.2	-1.1	0.3
Suffer from ‘nerves’	0.5	0.8	1.1	-0.8	-1.0
Knee pain experienced in last month	0.5	0.7	0.8	-0.8	-0.9
Medication: Gliclazide	0.5	0.5	0.9	0.4	-0.9
Guilty feelings	0.5	0.7	1.4	1.2	0.1
Hearing aid user	0.5	0.5	1.0	-0.2	-1.0
Mother’s age at death	0.5	0.7	1.4	-0.1	-1.2
Heart disease (siblings)	0.5	0.6	0.7	-0.8	-0.7
Reaction Time	0.4	0.7	1.1	-1.1	-0.5
Smoking Status	0.4	1.0	1.5	0.7	1.2
Medication: Co-codamol	0.4	0.4	0.7	-0.4	-0.8
Serious illness, injury or assault to yourself	0.4	0.5	0.9	-0.2	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.5	1.0	-0.3	-1.0
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	2.1	0.7	1.5
Happiness	0.4	0.4	0.8	-0.4	-0.9
Loud music exposure frequency	0.4	0.5	0.5	0.6	0.7
Comparative height size at age 10	0.4	2.3	3.1	1.3	1.8
Medication: Aspirin	0.4	0.5	0.5	0.7	0.7
Illnesses of father: Heart disease	0.4	0.5	1.0	-1.0	0.3
Commuting to job workplace: Public transport	0.4	0.4	0.6	0.8	-0.5
Supplements: Calcium	0.4	0.5	0.7	-0.5	-0.8
Alzheimer’s Disease (including proxy)	0.3	0.4	0.7	-0.3	-0.8
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.1	0.1	-1.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.6	0.8	0.5
Ever had hysterectomy (womb removed)	0.3	0.3	0.3	-0.5	-0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	0.7	-0.8	-0.2
Trunk fat percentage	0.3	1.3	2.7	1.6	-0.1
Current tobacco smoking	0.3	0.5	0.6	-0.8	-0.6
Medication: Atenolol	0.3	0.3	0.6	-0.7	-0.3
Past tobacco smoking	0.3	0.5	0.5	-0.7	-0.7
Pain all over the body in last month	0.3	0.3	0.5	0.2	-0.7
Fluid intelligence score	0.3	0.7	0.7	-0.9	-0.8
Neuroticism score	0.3	0.7	1.2	0.4	-1.1
Arm fat percentage (right)	0.3	1.3	2.7	-0.0	-1.6
Trunk fat-free mass	0.3	2.0	2.6	-1.6	-1.2
Pulse rate	0.3	0.5	0.8	0.9	0.3
Lung cancer (father)	0.3	0.4	0.5	-0.7	-0.5
Trunk predicted mass	0.3	1.8	2.3	-1.5	-1.1
Breastfed as a baby	0.3	0.4	0.7	-0.0	-0.8
Neck or shoulder pain in last month	0.3	0.4	0.5	0.6	0.7
Age at last live birth	0.3	0.4	0.4	0.6	0.6
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.5	-0.7	-0.4
Eye problems/disorders: Glaucoma	0.3	0.3	0.5	0.2	-0.7
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.5	0.4	0.7
Average weekly beer plus cider intake	0.3	0.5	0.9	0.9	-0.1
Pain experienced in last month	0.3	0.5	0.7	-0.6	-0.9
Neuroticism (Nagel 2018)	0.2	0.4	0.7	-0.3	-0.8
Alzheimer’s Disease (in mother)	0.2	0.2	0.3	0.3	0.6
Crohns Disease (2017)	0.2	0.4	0.8	-0.9	-0.3
Major Depression (MDD)	0.2	0.2	0.4	-0.1	0.6
Prostate Cancer	0.2	0.2	0.4	-0.7	-0.0
Fasting Glucose	0.2	0.3	0.5	-0.3	-0.7
Vitamin and mineral supplements	0.2	0.3	0.4	0.6	0.4
Trunk fat mass	0.2	1.0	1.9	1.4	-0.0
Nervous feelings	0.2	0.4	0.8	-0.3	-0.9
Hearing difficulty/problems with background noise	0.2	0.3	0.6	0.2	-0.8
Medication: Ramipril	0.2	0.3	0.6	-0.1	-0.8
Worrier / anxious feelings	0.2	0.4	0.8	-0.1	-0.9
Depression (self-reported)	0.2	0.2	0.4	0.6	0.3
Arm fat mass (right)	0.2	1.0	1.9	-0.2	-1.4
Tense / ‘highly strung’	0.2	0.3	0.6	-0.1	-0.8
Headache pain in last month	0.2	0.4	0.7	-0.8	-0.3
Glaucoma (self-reported)	0.2	0.2	0.5	-0.0	-0.7
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.4	-0.7	-0.3
Body fat percentage	0.2	0.7	1.2	1.1	-0.3
Leg fat percentage (right)	0.2	0.8	1.0	-0.8	-1.0
Medication for pain relief, constipation, heartburn	0.2	0.3	0.3	0.5	0.5
Whole body fat mass	0.2	0.7	1.3	1.1	-0.2
Alcohol intake frequency.	0.2	0.4	0.6	0.8	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.6	0.1	-0.8
Supplements: Vitamin C	0.2	0.3	0.5	-0.7	-0.1
Arm fat percentage (left)	0.2	0.9	1.7	0.4	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.4	-0.1	0.6
Mineral and other dietary supplements	0.2	0.2	0.5	0.7	0.0
Arm fat mass (left)	0.2	0.8	1.6	-0.0	-1.3
Wears glasses or contact lenses	0.2	0.2	0.4	0.7	0.1
Ever taken oral contraceptive pill	0.2	0.2	0.4	-0.6	-0.4
Leg fat percentage (left)	0.2	0.7	1.1	-0.6	-1.0
Arm fat-free mass (left)	0.2	1.1	1.4	-1.2	-0.9
Risk taking	0.2	0.3	0.5	-0.3	-0.7
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.3	-0.5	0.5
Ever depressed for a whole week	0.2	0.3	0.5	-0.2	0.7
Commuting to job workplace: Cycle	0.2	0.3	0.3	-0.5	-0.6
Cholesterol lowering medication	0.2	0.3	0.4	-0.4	-0.6
Schizophrenia (2018)	0.1	0.3	0.3	-0.5	-0.5
Breast Cancer	0.1	0.1	0.2	-0.2	0.5
Mean Putamen Volume	0.1	0.1	0.2	-0.3	-0.4
Blood Red Count	0.1	0.6	1.3	1.1	0.0
Blood White Count	0.1	0.5	1.0	-1.0	-0.2
BMI	0.1	0.6	1.1	0.2	-1.1
Neuroticism	0.1	0.1	0.1	0.4	-0.4
Average weekly spirits intake	0.1	0.2	0.3	-0.2	-0.5
Angina	0.1	0.1	0.3	0.1	-0.5
Leg fat-free mass (left)	0.1	0.4	0.7	0.1	-0.9
Maternal smoking around birth	0.1	0.1	0.1	-0.2	0.4
Age when periods started (menarche)	0.1	0.1	0.3	-0.0	-0.5
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	0.4	-0.1
High blood pressure (mother)	0.1	0.1	0.2	-0.2	-0.5
Leg predicted mass (left)	0.1	0.3	0.5	0.2	-0.7
Qualifications: None of the above	0.1	0.2	0.2	-0.4	-0.5
Heart attack	0.1	0.1	0.1	0.3	-0.3
Weight	0.1	0.3	0.5	0.1	-0.7
Time employed in main current job	0.1	0.1	0.2	-0.3	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.2	-0.2	0.4
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.3	0.5	0.0
Blood clot in the leg (DVT)	0.1	0.1	0.2	0.3	-0.4
Medication: Amlodipine	0.1	0.1	0.2	-0.4	-0.3
Angina (self-reported)	0.1	0.2	0.3	-0.1	-0.6
Heart disease (mother)	0.1	0.1	0.1	0.3	-0.2
Leg fat mass (right)	0.1	0.3	0.5	0.1	-0.7
Overall health rating	0.1	0.3	0.6	0.0	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.2	-0.3	-0.5
Whole body fat-free mass	0.1	0.8	0.9	-0.8	-1.0
Leg fat-free mass (right)	0.1	0.3	0.5	0.3	-0.7
Average weekly red wine intake	0.1	0.2	0.4	0.6	0.1
Commuting to job workplace: Walk	0.1	0.1	0.2	0.5	-0.2
Whole body water mass	0.1	0.8	0.9	-0.8	-1.0
Leg predicted mass (right)	0.1	0.4	0.6	0.3	-0.8
Miserableness	0.1	0.1	0.3	-0.0	-0.5
Illnesses of father: High blood pressure	0.1	0.2	0.3	0.6	-0.2
Basal metabolic rate	0.1	0.7	1.0	-0.7	-1.0
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.2	0.5	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	0.4	-0.3
Leg fat mass (left)	0.1	0.3	0.6	0.1	-0.8
Arm predicted mass (left)	0.1	0.6	0.8	-0.9	-0.7
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.1	-0.1	-0.3
Verbal and Numeric Reasoning (VNR)	0.0	0.0	0.0	-0.1	-0.1
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.1	0.2
Schizophrenia (2014)	0.0	0.0	0.0	-0.0	-0.2
Blood Eosinophil Count	0.0	0.2	0.3	-0.6	0.2
Blood Platelet Count	0.0	0.5	0.9	-0.4	0.9
Hair Pigment	0.0	0.1	0.1	-0.3	-0.3
Tanning	0.0	0.1	0.2	-0.4	-0.1
Sensitivity / hurt feelings	0.0	0.1	0.2	0.1	-0.4
Supplements: Glucosamine	0.0	0.0	0.0	0.2	-0.1
Number of incorrect matches in round	0.0	0.1	0.1	-0.3	-0.3
Alcohol usually taken with meals	0.0	0.1	0.1	-0.3	0.2
Medication: Simvastatin	0.0	0.0	0.0	-0.1	-0.1
Exposure to tobacco smoke at home	0.0	0.0	0.0	0.1	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.1	0.1	-0.1	-0.4
Birth weight	0.0	0.0	0.0	-0.2	0.1
Arm fat-free mass (right)	0.0	0.2	0.3	-0.5	-0.4
Comparative body size at age 10	0.0	0.1	0.1	0.3	0.3
Mean time to correctly identify matches	0.0	0.0	0.0	-0.1	-0.0
Arm predicted mass (right)	0.0	0.2	0.3	-0.6	-0.4
Osteoporosis (self-reported)	0.0	0.0	0.1	-0.3	-0.1
Osteoarthritis (self-reported)	0.0	0.1	0.1	0.1	-0.3
Smoking status: Current	0.0	0.0	0.1	-0.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.0	0.0	-0.1
Financial situation satisfaction	0.0	0.0	0.0	-0.0	0.2
High cholesterol (Self-reported)	0.0	0.0	0.0	0.1	0.1
Ever smoked	0.0	0.0	0.0	0.0	0.0
Irritability	0.0	0.1	0.1	0.4	-0.0

Hub : Genes

BMP4

Models

Trait associations