Best TWAS P=1.27e-14 · Best GWAS P=3.32e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP11-95P2.1 | 0.12 | 0.01 | lasso | 3 | 0.02 | 1.0e-02 | -6.6 | 6.5 | 8.2e-11 | -0.63 | 0.04 | 0.23 | FALSE |
| 2 | GTEx | Brain Nucleus accumbens basal ganglia | HMOX2 | 0.28 | -0.01 | lasso | 5 | -0.01 | 7.1e-01 | -4.8 | 5.2 | 2.0e-07 | 0.09 | 0.08 | 0.06 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | RP11-95P2.1 | 0.13 | 0.11 | lasso | 3 | 0.12 | 2.0e-09 | -6.7 | 7.2 | 7.4e-13 | -0.80 | 0.11 | 0.89 | FALSE |
| 4 | GTEx | Thyroid | RP11-95P2.1 | 0.15 | 0.10 | lasso | 5 | 0.10 | 3.9e-08 | -7.2 | 7.7 | 1.3e-14 | -0.96 | 0.03 | 0.97 | TRUE |