Hub : Genes

HMOX2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1270 0.0430 6.1e-05 0.047 NA 0.015 NA 0.042 9.9e-05 NA 1.9e-02 NA 2.2e-04
2 GTEx Artery Tibial 0.1860 0.0508 3.3e-06 0.135 NA 0.148 NA 0.138 1.0e-10 NA 1.1e-11 NA 5.8e-11
3 GTEx Brain Cerebellum 0.2140 0.0700 7.1e-04 0.147 NA 0.116 NA 0.138 4.2e-05 NA 2.8e-04 NA 7.2e-05
4 GTEx Brain Nucleus accumbens basal ganglia 0.2790 0.1110 3.2e-03 -0.011 NA -0.010 NA -0.010 9.5e-01 NA 7.7e-01 NA 7.1e-01
5 GTEx Muscle Skeletal 0.2518 0.0466 4.5e-10 0.090 NA 0.095 NA 0.116 4.0e-09 NA 1.3e-09 NA 1.8e-11
6 GTEx Nerve Tibial 0.2356 0.0600 4.5e-07 0.072 NA 0.042 NA 0.069 8.8e-06 NA 5.6e-04 NA 1.2e-05
7 GTEx Thyroid 0.1240 0.0440 6.9e-04 0.063 NA 0.031 NA 0.042 1.3e-05 NA 2.0e-03 NA 3.3e-04
8 TCGA Brain Lower Grade Glioma 0.0227 0.0138 8.4e-04 0.030 0.017 0.016 NA 0.017 1.9e-04 0.0043 5.1e-03 NA 3.9e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.8 2.2 -0.1 -1.5 -0.9 0.1 -1.3 0.4 -1.2 0.6
Bipolar Disorder or Schizophrenia 2.5 6.1 9.5 2.9 0.6 2.9 -2.3 -0.4 3.1 2.9 2.9
Depressed Affect (Nagel 2018) 0.8 1.7 3.6 1.3 1.8 0.0 -0.6 1.9 1.3 0.3 1.8
Depression (Nagel 2018) 0.4 0.6 1.6 0.9 0.7 0.3 -0.9 1.0 0.3 -0.2 1.2
Intelligence (Savage-Jansen 2018) 1.2 3.6 5.8 -2.4 -1.6 -2.0 2.0 -1.4 -2.2 -1.4 -1.9
Neuroticism (Nagel 2018) 0.5 1.1 3.5 0.5 1.6 -0.8 0.0 1.9 0.7 -0.6 1.2
Schizophrenia (2018) 5.6 11.6 22.5 3.8 2.0 4.4 -3.0 0.6 3.6 4.7 3.3
Schizophrenia vs Biploar Disorder 2.2 2.9 6.4 1.7 1.8 2.3 -1.3 1.0 1.2 2.5 1.2
Worry (Nagel 2018) 0.2 0.4 1.1 0.6 0.6 -0.1 -0.1 0.7 1.0 -0.4 1.0
Alzheimer’s Disease (in mother) 0.2 0.2 0.5 0.3 0.7 0.2 0.3 0.3 0.7 -0.2 0.5
Alzheimer’s Disease (in father) 1.1 1.2 2.4 -1.5 0.2 -0.9 1.4 0.0 -1.6 -1.0 -1.2
Alzheimer’s Disease (including proxy) 0.3 0.4 1.1 -0.6 0.8 -0.3 1.1 0.5 -0.3 -0.7 -0.3
Crohns Disease (2017) 0.6 1.3 2.6 1.3 -0.3 1.5 -1.6 -1.4 1.0 0.6 1.0
Irritable Bowel Disease (IBD) 0.3 0.7 1.6 0.9 -0.1 0.8 -1.3 -0.6 0.9 0.5 1.0
Ulcerative Colitis (UC) 0.1 0.1 0.3 0.1 -0.0 -0.3 -0.2 0.5 0.4 0.2 0.5
Major Depression (MDD) 0.8 1.0 3.5 1.2 0.7 0.1 -1.9 0.0 1.1 0.7 0.9
Reaction Time 2.0 3.8 7.6 2.4 -0.6 1.9 -2.6 -1.3 2.7 0.6 2.1
Verbal and Numeric Reasoning (VNR) 0.9 2.2 3.8 -1.9 -1.3 -1.4 1.5 -1.0 -1.6 -1.3 -1.6
Breast Cancer 0.3 0.6 1.5 0.5 1.2 0.5 -0.0 1.2 0.9 0.3 0.8
Ovarian Cancer 0.0 0.1 0.2 -0.2 0.1 -0.3 0.2 0.5 0.1 -0.1 -0.2
Prostate Cancer 3.0 4.2 12.6 1.1 3.5 0.9 -0.5 2.8 0.8 2.8 1.6
Age at First Birth 0.5 0.7 2.2 -0.5 -1.5 -0.3 0.2 -1.0 -0.9 -0.8 -0.8
Bipolar Disorder (2011) 1.4 1.3 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3
Body Mass Index (BMI) (2010) 0.6 0.8 2.7 1.1 0.0 1.0 -1.6 -0.3 0.2 0.8 0.9
Coronary Artery Disease (CAD) 0.1 0.1 0.2 0.1 0.5 -0.1 -0.3 0.3 0.3 -0.4 -0.2
Crohns Disease (2012) 0.8 1.3 4.2 1.3 -0.4 1.1 -2.1 -1.1 1.2 -0.2 0.6
Mean Putamen Volume 1.4 1.6 3.5 -1.7 -0.9 -1.0 1.9 -0.7 -1.5 -0.8 -1.1
Fasting Glucose 4.5 5.4 8.3 2.6 0.1 2.9 -2.7 -1.3 2.4 2.8 2.4
HbA1C 0.7 0.8 2.4 0.7 -1.1 0.4 -1.0 -1.6 0.6 0.7 0.3
HDL Cholesterol 1.6 2.6 5.4 -2.0 -0.7 -2.3 2.1 0.7 -1.1 -1.1 -1.9
LDL Cholesterol 0.7 1.1 2.4 -1.5 -0.6 -1.5 0.8 -0.4 -0.7 -0.2 -1.5
Lupus 1.1 1.7 3.5 -1.4 -1.9 -0.9 0.6 -1.9 -0.6 -1.0 -1.3
Neuroticism (2016) 0.4 0.5 2.2 0.3 0.9 -0.7 -0.3 1.5 -0.2 0.2 0.7
Primary Biliary Cirrhosis 0.9 1.3 2.9 1.3 -0.8 1.0 -1.4 -1.7 0.8 0.7 1.0
Rheumatoid Arthritis 0.7 0.9 2.5 -0.9 0.2 -1.6 0.7 0.8 -0.4 -1.5 -0.8
Schizophrenia (2014) 5.3 11.8 19.9 3.7 2.5 4.2 -2.7 1.2 3.8 4.5 3.6
Triglycerides 0.3 0.5 1.3 0.7 -0.5 0.8 -0.9 -1.1 0.4 0.2 0.4
Type 2 Diabetes (T2D) (2012) 1.5 1.7 4.0 1.7 0.3 1.5 -2.0 -0.7 1.6 0.1 1.1
Ulcerative Colitis 0.2 0.3 0.8 0.3 -0.9 0.1 -0.7 -0.8 0.7 0.1 0.4
Blood Eosinophil Count 2.7 21.1 31.1 5.6 2.7 5.0 -5.1 1.0 5.1 4.8 5.4
Blood Platelet Count 2.7 31.5 45.6 6.5 1.4 6.4 -6.3 -1.6 6.8 6.2 6.3
Blood Red Count 0.1 1.0 2.1 -0.5 -1.4 -0.7 -0.4 -1.2 -1.3 -1.4 -0.1
Blood White Count 2.6 19.0 29.9 5.0 1.0 5.1 -5.5 -1.0 4.6 5.0 4.7
Heel T-Score 1.8 14.4 22.9 4.8 1.6 4.3 -4.2 -0.2 4.8 3.2 4.5
BMI 0.2 1.0 3.7 -1.1 0.0 -1.0 0.1 0.6 -1.9 -1.1 -0.4
Height 0.3 5.8 13.5 -2.0 -2.5 -2.8 1.0 -2.5 -2.5 -3.7 -1.2
Waist Hip Ratio (WHR) 13.1 58.7 91.6 9.0 6.2 7.7 -7.5 3.2 9.6 7.4 8.8
Systolic Blood Pressure 2.5 12.6 26.4 3.6 0.4 5.1 -3.9 -1.0 3.5 5.1 2.5
Smoking Status 0.2 0.4 1.8 -0.1 1.0 -0.3 0.1 1.3 0.3 0.6 -0.3
Allergy or Eczema 0.4 1.1 2.2 -1.3 0.4 -1.5 0.9 1.0 -1.2 -0.7 -0.8
Cardiovascular Disease 2.0 6.8 13.8 2.6 1.9 3.7 -2.3 1.0 2.3 3.7 2.1
Hypothyroidism (self reported) 0.2 0.5 1.8 0.7 0.5 0.8 -0.6 0.0 1.3 -0.1 0.8
Respiratory disease 1.0 2.3 4.2 1.8 1.3 1.5 -1.8 0.4 1.5 1.1 2.1
Type 2 Diabetes (T2D) (2018) 0.7 1.3 2.3 1.2 0.1 1.4 -1.5 -0.5 1.1 1.5 1.0
Lung FEV1/FVC ratio 2.8 14.2 27.0 -4.8 -1.8 -4.4 5.2 -0.7 -3.1 -3.7 -4.1
Lung FVC 3.0 15.2 26.7 5.0 1.4 5.2 -4.7 -1.5 3.5 3.8 4.2
Neuroticism 0.9 2.1 5.0 1.8 1.0 0.5 -1.3 0.9 2.2 0.7 2.1
Chronotype (morning person) 1.4 3.3 6.2 -1.6 -2.4 -1.3 1.0 -2.5 -0.6 -2.1 -2.0
Hair Pigment 0.7 19.7 34.5 -5.7 -1.2 -4.5 5.9 0.9 -5.1 -3.7 -5.4
Tanning 1.1 13.4 22.9 4.4 0.5 4.8 -4.5 -1.5 4.0 3.8 3.4
Hand grip strength (left) 0.9 2.4 6.9 2.1 0.0 1.5 -2.6 -0.5 1.3 0.2 2.0
Number of treatments/medications taken 0.1 0.2 0.8 -0.2 0.1 0.1 -0.2 0.1 0.9 0.6 -0.5
Average weekly spirits intake 2.2 2.7 5.3 2.1 -0.1 2.0 -2.2 -0.6 2.3 0.9 1.5
Sensitivity / hurt feelings 3.9 6.6 10.9 2.8 3.2 1.9 -2.4 2.3 2.2 2.1 3.3
Frequency of depressed mood in last 2 weeks 0.3 0.4 1.1 0.7 -0.4 0.3 -1.0 0.3 0.1 -0.2 1.0
Hearing difficulty/problems: Yes 0.6 0.8 2.3 0.4 1.5 0.5 -0.1 1.3 0.7 1.1 0.8
Relative age of first facial hair 0.7 1.4 3.8 0.9 -1.3 1.4 -1.1 -2.0 1.0 0.6 0.8
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 1.0 -1.0 -0.5 -0.8 0.7 -0.1 -1.0 -0.1 -0.1
Ever used hormone-replacement therapy (HRT) 3.0 3.8 6.9 -2.6 -0.3 -2.1 2.4 1.1 -2.2 -1.6 -2.3
Ever had hysterectomy (womb removed) 1.8 2.0 5.2 0.9 -1.6 1.7 -1.2 -2.3 1.3 1.2 0.4
Systolic blood pressure, automated reading 2.1 6.0 16.2 2.2 0.2 3.7 -2.6 -0.8 2.1 4.0 1.2
Eye problems/disorders: Diabetes related eye disease 1.7 1.8 3.5 1.8 0.7 1.3 -1.5 0.3 1.1 1.4 1.9
Angina 0.5 0.7 2.4 0.6 0.1 1.1 -0.8 -0.4 0.6 1.6 0.6
Medication for hormone replacement therapy 2.3 2.5 3.9 -1.7 -2.0 -1.7 1.5 -0.7 -1.4 -1.6 -1.8
Vitamin and mineral supplements 0.3 0.4 1.0 -0.0 -1.0 -0.0 -0.7 -0.9 0.8 0.0 -0.1
Supplements: Zinc 0.4 0.4 1.9 0.1 -0.7 0.9 0.2 -0.4 -0.3 1.4 -0.4
Medication: Co-codamol 1.6 1.9 4.9 -1.0 -1.6 -1.2 0.7 -1.3 -1.4 -2.2 -1.1
Medication: Metformin 1.6 2.3 4.3 1.8 0.5 1.9 -1.5 -0.7 1.4 2.1 1.5
Diabetes (father) 0.8 1.0 3.2 -0.8 -1.8 -0.4 0.2 -1.4 0.0 -0.9 -1.0
Diabetes (mother) 0.5 0.6 1.8 1.0 -0.2 1.0 -1.3 0.0 0.7 0.4 0.6
Severe depression (siblings) 0.4 0.5 1.7 0.5 1.3 0.3 -0.4 0.7 0.3 0.7 0.8
Pack years adult smoking proportion 1.8 2.7 5.1 2.3 0.4 1.8 -2.1 -0.3 2.2 0.7 1.9
Impedance of leg (right) 0.4 1.9 3.0 1.6 1.1 1.7 -1.3 0.1 1.5 1.2 1.7
Leg fat-free mass (left) 1.1 5.7 10.8 -2.7 -1.3 -3.0 1.7 -0.2 -3.0 -3.3 -2.0
Trunk fat percentage 0.2 0.8 2.0 0.8 0.7 0.8 -1.4 0.6 -0.0 0.5 1.3
Hand grip strength (right) 0.6 1.6 4.0 1.5 -1.0 1.2 -2.0 -1.3 0.8 0.1 1.5
Townsend deprivation index at recruitment 2.1 3.0 6.0 2.1 0.9 1.1 -1.9 0.6 2.5 1.6 2.2
Current tobacco smoking 1.4 2.4 6.2 1.7 0.4 1.3 -2.5 -0.1 2.2 1.7 0.6
Average weekly fortified wine intake 1.2 1.4 2.9 1.3 0.5 0.7 -1.6 0.0 1.7 0.8 1.6
Maternal smoking around birth 0.2 0.2 1.1 -0.1 0.5 -0.3 0.2 1.1 0.0 -0.6 0.2
Fed-up feelings 0.5 0.8 2.1 1.2 0.6 0.3 -0.8 0.6 1.5 -0.4 1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 1.0 2.2 1.0 0.9 0.3 -1.2 1.3 0.6 0.3 1.5
Relative age voice broke 0.3 0.4 1.6 -0.6 -1.3 -0.1 0.3 -1.1 -0.1 -0.5 -0.2
Taking other prescription medications 0.4 0.7 1.7 0.7 -0.1 0.9 -1.3 -0.8 0.9 0.8 0.5
Age when periods started (menarche) 0.2 0.5 0.8 -0.8 -0.5 -0.7 0.9 -0.6 -0.4 0.3 -0.9
Bilateral oophorectomy (both ovaries removed) 0.9 1.0 1.8 0.8 -1.0 1.0 -1.3 -1.3 0.7 0.9 0.8
Heel bone mineral density (BMD) T-score, automated (left) 1.2 2.8 5.3 1.9 0.0 1.7 -2.3 -0.1 1.9 2.1 1.4
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 0.8 -0.8 0.8 -0.9 0.2 0.8 -0.4 -0.6 -0.8
Qualifications: CSEs or equivalent 2.0 2.6 5.5 1.2 2.2 1.2 -0.1 2.2 0.7 2.4 1.5
Serious illness, injury or assault to yourself 0.7 0.9 1.7 -1.1 -0.9 -1.1 0.7 0.1 -1.3 -1.0 -0.5
High blood pressure 0.6 1.7 7.4 0.8 0.7 1.7 -1.3 0.5 0.5 2.7 0.4
Hayfever, allergic rhinitis or eczema 0.3 0.6 1.4 -1.1 0.2 -1.2 1.0 0.5 -0.6 -0.7 -0.6
Multivitamins +/- minerals 0.1 0.2 0.8 0.1 0.9 0.1 0.5 0.3 -0.3 -0.3 0.2
Stomach or abdominal pain in last month 2.5 3.1 5.5 -2.1 -1.0 -2.3 1.6 0.1 -2.3 -1.8 -1.6
Supplements: Glucosamine 1.1 1.4 2.3 -1.5 0.6 -1.3 1.4 1.4 -1.4 -0.4 -1.1
Diverticular disease/diverticulitis (self-reported) 2.3 2.8 5.0 -1.8 -0.3 -2.2 1.7 0.2 -2.2 -2.2 -1.1
Medication: Atenolol 0.7 0.9 2.3 0.8 0.7 1.2 -1.1 0.6 0.2 1.5 0.8
Medication: Levothyroxine sodium 0.3 0.5 2.5 -0.0 1.6 0.1 -0.1 1.1 0.3 0.4 0.4
Sitting height 3.0 21.2 37.2 -5.2 -3.1 -6.1 4.0 -1.2 -5.7 -5.3 -4.1
Chronic bronchitis/emphysema (father) 2.7 3.2 6.3 1.8 1.3 1.9 -1.7 0.4 1.9 2.5 1.9
High blood pressure (mother) 0.4 0.6 1.3 0.6 0.9 0.9 -0.5 1.2 -0.2 1.1 0.4
Body mass index (BMI) 0.1 0.5 2.5 -0.7 0.3 -0.3 -0.2 0.6 -1.6 -0.1 -0.2
Impedance of leg (left) 0.3 1.5 3.1 1.5 0.5 1.8 -1.1 -0.3 1.5 1.0 1.4
Leg predicted mass (left) 1.1 6.1 11.5 -2.8 -1.4 -3.0 1.9 -0.3 -3.1 -3.4 -2.2
Trunk fat mass 0.1 0.4 1.6 -0.5 -0.1 -0.5 -0.4 0.3 -1.3 -0.8 0.3
Waist circumference 0.3 1.3 3.6 1.1 0.9 1.0 -1.5 0.5 0.6 0.7 1.9
Number of incorrect matches in round 0.4 0.7 1.4 0.8 -0.6 1.2 -1.0 -1.0 0.3 0.6 0.7
Past tobacco smoking 0.5 1.0 2.0 1.2 0.4 1.0 -1.4 -0.5 1.0 0.9 1.2
Alcohol usually taken with meals 1.0 1.5 2.7 -1.5 -1.0 -1.3 1.6 -0.3 -1.5 -1.1 -1.0
Nervous feelings 0.2 0.4 1.1 0.6 0.5 0.1 -0.4 0.8 0.5 0.1 1.1
Frequency of tenseness / restlessness in last 2 weeks 1.3 2.1 6.0 1.1 1.6 0.0 -1.4 2.4 1.4 0.1 1.6
Hearing difficulty/problems with background noise 0.1 0.1 0.3 0.1 -0.2 0.5 -0.2 -0.3 0.6 0.5 0.0
Hair/balding pattern: Pattern 2 0.9 1.2 3.9 -0.6 -2.0 -0.2 0.5 -1.5 -1.1 -0.8 -0.8
Had menopause 0.1 0.2 0.4 -0.6 0.2 -0.6 0.3 0.0 -0.3 -0.5 -0.6
Had other major operations 1.5 1.8 4.4 -1.5 -1.9 -0.8 0.6 -1.1 -0.6 -1.3 -2.1
Forced vital capacity (FVC) 0.2 0.6 1.8 0.8 -0.6 0.6 -0.9 -1.3 0.3 -0.2 0.9
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.2 4.8 1.6 -0.8 1.6 -2.2 -0.9 2.0 1.1 1.0
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 0.8 0.4 0.1 0.9 -0.7 -0.0 0.2 0.6 0.7
Qualifications: None of the above 0.5 1.1 4.0 -0.2 -1.9 0.3 -0.5 -2.0 0.7 -0.6 -0.7
Financial difficulties in last 2 years 5.8 7.8 12.0 3.4 2.5 2.5 -3.4 2.0 2.8 1.9 3.5
Mouth/teeth dental problems 0.6 0.9 2.5 1.1 -0.1 0.9 -1.6 -0.8 0.5 0.4 1.3
Heart attack 0.2 0.3 1.2 0.1 -0.4 0.6 -0.3 -0.8 0.2 1.1 -0.1
Allergy 0.1 0.2 0.6 0.5 -0.2 0.7 0.0 -0.4 0.0 0.8 0.1
Pain all over the body in last month 0.4 0.4 0.9 0.4 1.0 0.3 -0.3 0.7 0.8 0.5 0.5
Diabetes (self-reported) 0.8 1.2 1.8 1.2 -0.4 1.2 -1.3 -1.3 1.2 1.1 0.8
Hayfever/allergic rhinitis (self-reported) 0.5 0.6 1.2 0.3 -1.1 0.5 -0.9 -1.1 1.1 -0.3 -0.4
Medication: Ramipril 0.3 0.3 0.7 0.4 -0.6 0.8 -0.8 -0.8 0.2 0.3 0.1
Medication: Simvastatin 0.5 0.8 2.2 0.8 0.8 1.2 -0.5 0.1 0.8 1.5 0.9
Fluid intelligence score 2.0 4.1 7.3 -2.7 -1.5 -2.5 1.8 -0.4 -2.4 -1.5 -2.3
Illnesses of siblings 0.2 0.3 1.1 0.4 1.0 0.3 -0.0 0.9 0.5 0.0 0.5
Neuroticism score 0.7 1.5 3.1 1.3 1.3 0.2 -0.7 1.4 1.7 0.3 1.8
Weight 0.7 3.6 8.2 -2.2 -1.2 -2.2 1.0 -0.5 -2.9 -2.4 -1.5
Impedance of arm (right) 0.9 4.1 8.1 2.7 0.9 1.9 -2.4 -0.2 2.8 1.3 2.4
Arm fat percentage (right) 0.3 1.0 2.5 0.8 1.1 1.0 -1.6 0.8 -0.2 0.8 1.1
Trunk fat-free mass 2.3 13.4 20.1 -4.3 -2.7 -4.2 3.3 -1.5 -4.5 -4.2 -3.5
Hip circumference 1.4 6.0 13.2 -2.8 -2.2 -2.5 1.4 -1.3 -3.6 -3.0 -1.9
Time employed in main current job 0.3 0.4 0.9 0.6 0.4 0.8 -1.0 0.0 0.4 0.6 0.5
Alcohol intake versus 10 years previously 0.7 1.0 2.0 -1.1 -0.4 -1.3 1.4 -0.4 -1.0 -1.3 -0.3
Father’s age at death 0.6 0.9 3.3 -0.1 1.5 -0.4 0.5 1.8 -0.6 0.6 0.6
Worrier / anxious feelings 0.2 0.4 1.5 -0.1 1.0 -0.1 0.3 1.2 0.0 -0.4 0.4
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.2 0.9 0.0 0.4 -0.4 0.0 0.8 0.1 -0.9 0.3
Falls in the last year 0.4 0.6 1.9 0.8 0.7 0.3 -0.8 -0.1 0.8 0.4 1.4
Hair/balding pattern: Pattern 3 0.7 1.0 4.5 0.1 2.1 -0.2 0.1 1.7 0.5 0.4 0.7
Number of live births 5.9 8.4 15.2 3.6 -0.0 3.4 -3.9 -1.7 3.2 1.7 3.3
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 3.3 0.1 -1.1 0.1 0.1 -1.8 -0.1 -1.1 0.3
Pulse rate 0.2 0.3 2.2 0.6 0.3 0.4 -0.1 0.2 1.5 -0.2 -0.1
Happiness 0.4 0.4 1.8 0.0 1.4 -0.6 -0.4 0.8 -0.3 -0.3 0.6
Noisy workplace 0.1 0.2 0.7 -0.6 -0.4 -0.1 0.0 -0.5 0.0 -0.1 -0.9
Qualifications: A levels/AS levels or equivalent 0.5 1.0 2.2 -1.2 -0.2 -1.4 0.8 0.1 -1.1 -1.5 -0.9
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 1.0 -0.8 0.2 -1.0 0.2 0.7 -0.8 -0.6 -0.8
Mouth/teeth dental problems: Dentures 0.8 1.4 3.8 -0.6 1.8 -0.7 0.9 2.0 -1.3 -0.1 -0.6
Asthma 0.6 1.1 2.0 1.2 0.6 1.1 -1.4 -0.5 1.4 0.4 1.2
Medication: Ibuprofen (e.g. Nurofen) 2.5 3.2 6.3 -1.7 -1.9 -2.1 1.5 -1.2 -0.7 -2.5 -2.0
Medication: Cholesterol lowering 1.6 2.5 5.6 1.2 2.2 0.8 -1.0 1.9 1.1 2.4 1.4
Depression (self-reported) 0.7 0.9 2.2 -0.3 1.3 -1.0 -0.1 1.5 -1.3 -0.3 0.4
Medication: Lansoprazole 0.3 0.4 0.9 0.3 0.7 0.9 -0.0 0.4 0.8 0.9 0.2
Prospective memory result 1.0 1.2 2.1 1.0 -0.9 1.1 -0.9 -1.5 1.4 1.1 0.6
Lung cancer (father) 1.1 1.3 3.2 -1.0 0.8 -1.5 1.3 1.8 -0.8 -0.2 -0.8
Illnesses of mother 1.0 1.2 4.7 -0.8 -1.3 -0.4 0.8 -2.2 -0.7 -0.8 -0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.5 6.4 0.8 -1.6 0.6 -0.7 -2.5 0.4 -0.7 0.9
Pulse wave Arterial Stiffness index 0.2 0.3 0.7 -0.1 0.4 0.5 0.7 0.6 0.8 0.4 -0.3
Impedance of arm (left) 1.1 5.1 11.0 3.0 0.8 2.1 -2.4 -0.6 3.3 1.5 2.7
Arm fat mass (right) 0.1 0.6 2.7 -0.7 0.3 -0.6 -0.2 0.5 -1.6 -0.7 -0.2
Trunk predicted mass 2.4 13.8 20.9 -4.4 -2.7 -4.3 3.4 -1.5 -4.6 -4.3 -3.6
Standing height 1.2 11.7 24.3 -3.4 -3.2 -4.1 2.5 -2.6 -3.0 -4.9 -2.8
Length of working week for main job 1.5 1.7 3.2 -1.2 -1.7 -1.0 0.3 -0.9 -1.5 -1.8 -1.5
Exposure to tobacco smoke at home 1.5 1.6 3.1 1.5 0.3 1.7 -1.8 -0.4 0.9 1.2 1.5
Breastfed as a baby 0.2 0.3 0.6 -0.8 0.1 -0.6 0.7 0.2 0.2 -0.4 -0.6
Tense / ‘highly strung’ 0.8 1.3 2.1 1.2 -1.1 1.3 -1.0 -1.1 1.5 0.9 1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.5 2.3 4.4 -1.8 0.2 -2.1 1.5 1.2 -2.1 -0.6 -1.4
Hair/balding pattern: Pattern 4 0.0 0.1 0.3 0.3 -0.1 0.4 -0.2 -0.3 0.6 0.0 0.4
Birth weight of first child 0.4 0.8 2.2 -1.0 -0.4 -1.1 1.1 0.2 -0.5 -0.6 -1.5
Peak expiratory flow (PEF) 0.4 0.9 2.5 -1.0 -0.6 -1.0 1.0 -0.9 -0.8 -1.6 -0.6
Pulse wave reflection index 0.5 0.6 1.7 -1.1 -0.1 -0.4 1.3 0.4 -1.1 0.4 -0.7
Ever highly irritable/argumentative for 2 days 0.9 1.0 3.0 1.1 0.7 0.4 -0.7 0.3 1.2 1.3 1.7
Loud music exposure frequency 2.0 2.2 4.1 -1.6 -1.0 -1.6 1.8 -0.4 -1.1 -1.6 -2.0
Qualifications: O levels/GCSEs or equivalent 0.6 1.0 2.8 0.7 1.7 0.2 -0.9 1.5 -0.1 0.2 1.0
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 1.5 0.5 -0.4 0.8 -0.5 -0.1 1.1 1.2 0.3
Blood clot in the leg (DVT) 0.5 0.6 2.3 -0.2 -1.5 -0.6 -0.6 -1.1 0.2 -0.7 0.0
Medication: Paracetamol 0.1 0.2 0.7 -0.1 0.5 -0.3 0.2 0.8 0.3 -0.5 -0.2
Headache pain in last month 0.3 0.6 3.1 -0.3 0.4 -1.0 0.1 0.4 0.0 -1.7 -0.2
Medication for cholesterol, blood pressure or diabetes 0.9 1.5 4.8 -0.3 -2.2 -0.0 0.2 -2.0 -0.2 -1.6 -0.6
Glaucoma (self-reported) 0.1 0.1 0.6 -0.1 0.1 -0.3 0.0 0.1 -0.3 0.8 0.2
Gout (self-reported) 1.0 1.4 4.9 0.6 -1.4 1.4 -1.0 -2.2 0.8 0.7 0.4
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 1.4 0.6 0.9 0.7 -0.4 0.4 1.2 0.2 0.9
Medication: Amlodipine 1.1 1.6 6.1 1.0 0.6 2.0 -0.2 0.3 0.8 2.5 0.9
Medication: Ventolin 100micrograms inhaler 0.7 0.9 1.4 1.0 -0.4 1.2 -1.1 -1.2 1.1 0.4 0.7
Birth weight 3.8 8.3 11.6 -3.1 -3.2 -2.2 2.9 -2.1 -2.7 -3.4 -3.2
Chronic bronchitis/emphysema (mother) 0.7 0.8 2.5 -0.5 -1.6 -1.0 0.2 -0.8 -0.2 -1.3 -0.4
High blood pressure (siblings) 0.1 0.2 1.2 0.2 0.0 0.4 -0.2 -0.2 0.1 1.1 0.2
Forced vital capacity (FVC), Best measure 0.6 2.0 5.2 1.5 -1.2 1.0 -1.9 -2.3 0.9 -0.1 1.3
Body fat percentage 0.2 0.7 1.9 0.6 0.6 0.9 -1.4 0.6 -0.3 0.5 1.1
Leg fat percentage (right) 0.1 0.4 1.1 -0.1 0.7 0.4 -0.7 0.7 -1.0 0.3 0.7
Arm fat-free mass (right) 1.6 8.1 14.0 -3.4 -1.8 -3.2 2.5 -0.7 -3.7 -3.5 -2.6
Exposure to tobacco smoke outside home 1.4 1.8 3.2 1.8 1.1 1.6 -1.7 0.3 1.3 0.7 1.6
Comparative body size at age 10 0.2 0.7 2.6 -0.2 1.5 0.1 0.3 1.6 -0.5 -0.3 0.1
Number of full brothers 0.8 1.0 2.0 1.1 -0.4 1.0 -1.4 -0.9 1.1 1.1 0.8
Worry too long after embarrassment 1.5 2.6 5.0 -1.7 1.1 -2.2 1.7 2.1 -1.3 -1.1 -1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.2 1.6 2.9 -1.5 0.4 -1.7 1.6 1.0 -1.7 -0.6 -0.9
Wheeze or whistling in the chest in last year 0.2 0.3 1.1 -0.2 0.9 -0.7 0.1 1.0 -0.2 -0.4 -0.4
Number of children fathered 1.4 1.5 4.1 -1.0 -2.0 -0.2 0.8 -1.9 -0.8 -0.7 -1.4
Reason for reducing amount of alcohol drunk: Health precaution 3.2 3.7 7.5 -1.8 -2.7 -1.5 1.2 -2.1 -1.6 -1.8 -2.3
Age at first live birth 0.4 0.7 1.4 -1.0 0.2 -1.2 1.1 -0.2 -0.9 -0.2 -1.0
Pulse wave peak to peak time 0.6 0.7 1.7 -0.5 -0.8 -1.0 -0.2 -0.8 -1.3 -1.0 -0.2
Health satisfaction 0.4 0.5 1.0 0.7 0.3 0.9 -0.8 -0.0 0.7 0.4 1.0
Shortness of breath walking on level ground 1.4 1.7 3.6 1.2 -0.7 1.4 -1.4 -1.4 1.9 0.6 1.2
Qualifications: College or University degree 0.3 0.8 2.4 -0.8 -0.6 -1.5 0.2 -0.8 -0.8 -1.5 0.0
Eye problems/disorders: None of the above 0.1 0.1 0.3 -0.2 0.4 -0.3 -0.0 0.6 -0.0 -0.5 -0.6
Mouth/teeth dental problems: Loose teeth 0.4 0.5 0.9 -0.8 -0.9 -0.5 0.8 -0.4 -0.7 -0.6 -0.8
Emphysema/chronic bronchitis 1.3 1.5 2.8 1.1 1.4 1.2 -1.1 1.3 0.9 1.7 0.9
Medication for pain relief, constipation, heartburn 0.2 0.3 0.7 0.3 0.7 0.4 -0.5 0.5 -0.9 -0.2 0.4
Neck or shoulder pain in last month 0.8 1.1 3.1 -1.2 0.1 -1.2 1.0 0.2 -0.8 -1.0 -1.7
Medication: Blood pressure 1.0 1.7 3.8 0.8 1.8 0.8 -1.0 1.8 0.7 1.9 0.8
Angina (self-reported) 0.9 1.2 3.8 0.9 0.6 1.4 -1.0 -0.0 1.0 1.9 0.9
Migraine (self-reported) 5.6 6.9 12.7 2.8 2.9 1.7 -3.0 1.9 2.3 2.5 3.6
Medication: Ibuprofen 0.4 0.5 1.6 -0.2 -0.8 -0.4 0.2 -0.5 0.7 -1.3 -0.7
Medication: Allopurinol 0.4 0.6 3.2 -0.1 -1.1 0.4 -0.1 -1.8 -0.0 -0.1 -0.1
Medication: Omeprazole 0.1 0.1 0.3 -0.4 -0.2 -0.6 0.5 0.2 -0.2 -0.2 -0.1
Medication: Seretide 50 evohaler 0.2 0.2 0.7 -0.2 0.1 0.0 -0.3 -0.2 0.8 0.6 -0.5
Mean time to correctly identify matches 1.9 3.6 5.7 1.9 -1.8 2.2 -1.9 -2.3 2.4 0.7 1.3
Heart disease (mother) 0.6 0.7 1.3 0.6 1.1 0.4 -1.1 1.1 0.9 0.4 0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.4 1.6 0.1 -0.6 0.4 -0.3 -1.3 -0.5 0.6 -0.1
Whole body fat mass 0.1 0.5 2.2 -0.6 -0.0 -0.5 -0.4 0.3 -1.5 -1.0 0.1
Leg fat mass (right) 0.2 0.9 4.1 -1.1 0.3 -0.7 0.1 0.7 -2.0 -1.1 -0.2
Arm predicted mass (right) 1.7 8.7 14.4 -3.5 -1.9 -3.3 2.7 -0.7 -3.8 -3.5 -2.8
Pulse rate, automated reading 0.6 1.9 5.4 0.9 1.7 1.3 -0.2 1.2 2.3 1.7 0.3
Alcohol intake frequency. 0.4 0.9 2.5 1.3 0.6 0.9 -1.0 -0.9 0.4 -0.0 1.6
Comparative height size at age 10 0.7 4.1 7.2 -2.4 -1.3 -2.7 1.4 -0.6 -1.7 -2.7 -2.3
Number of full sisters 0.5 0.6 1.3 -0.9 -0.6 -0.7 1.1 -0.1 -0.5 -0.8 -1.0
Suffer from ‘nerves’ 0.4 0.7 2.2 0.7 0.9 -0.2 -0.8 0.8 0.6 0.6 1.5
Overall health rating 1.0 2.1 3.1 1.4 1.7 1.1 -1.3 1.2 1.5 1.4 1.8
Chest pain or discomfort 0.4 0.6 1.6 0.0 1.2 -0.5 -0.0 1.3 0.5 0.9 0.5
Had major operations 0.4 0.4 0.9 -0.0 0.9 -0.8 -0.5 1.0 -0.5 0.3 0.7
Age at last live birth 0.4 0.5 1.2 -0.8 -0.1 -0.8 0.9 -0.5 -0.7 -0.5 -1.1
Family relationship satisfaction 0.5 0.6 1.3 0.6 1.1 -0.1 -1.1 0.6 0.2 0.4 1.0
Leg pain on walking 2.3 2.9 5.8 -2.1 0.5 -2.1 1.7 1.3 -2.4 -0.9 -1.7
Qualifications: NVQ or HND or HNC or equivalent 6.2 7.4 14.5 2.9 3.1 2.5 -2.3 2.1 1.8 3.8 2.7
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.6 0.0 -0.3 0.8 0.2 -0.5 0.4 0.7 -0.2
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 1.9 -0.6 -1.0 -0.7 0.8 -1.4 -0.4 -1.2 -0.6
Medication: Aspirin 1.6 2.1 5.3 1.3 -0.0 1.6 -1.4 -1.0 1.5 2.3 1.3
Supplements: Vitamin C 1.5 1.8 3.7 -1.4 -0.9 -1.2 1.6 -0.6 -1.9 -1.5 -1.3
Knee pain experienced in last month 2.0 3.0 6.0 -2.1 -0.9 -2.3 1.3 -0.5 -2.4 -1.8 -1.7
Hypertension (Self-reported) 0.7 2.0 8.0 1.0 0.5 2.0 -1.4 0.2 0.7 2.8 0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 1.2 -0.5 -0.2 0.0 1.1 0.1 0.5 -0.5 -0.9
Illnesses of father: Heart disease 0.6 0.8 2.9 0.1 -1.4 0.2 -1.0 -1.7 -0.4 0.7 0.1
Illnesses of siblings: Diabetes 0.1 0.2 0.7 0.1 -0.8 -0.2 -0.3 -0.4 -0.4 0.3 0.3
Smoking status: Previous 2.7 4.0 7.3 -2.5 -0.5 -2.1 2.7 0.9 -2.5 -1.7 -1.9
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 4.0 -0.7 -1.2 -0.9 0.3 -1.5 -1.0 -2.0 -0.7
Whole body fat-free mass 1.8 10.2 15.7 -3.7 -2.3 -3.7 2.7 -1.1 -4.0 -3.9 -3.0
Leg fat-free mass (right) 1.2 6.2 11.7 -2.8 -1.8 -3.0 1.9 -0.7 -3.0 -3.4 -2.2
Arm fat percentage (left) 0.3 1.1 2.5 1.0 1.1 1.1 -1.6 0.8 0.0 0.9 1.3
Average weekly red wine intake 1.0 1.4 2.9 -1.0 -1.7 -0.4 0.5 -1.4 -1.0 -1.5 -1.3
Handedness (chirality/laterality): Left-handed 2.6 3.1 5.1 -1.8 -2.0 -1.8 1.6 -1.2 -1.0 -2.1 -2.3
Mood swings 0.2 0.4 1.0 0.4 1.0 -0.5 -0.2 1.0 0.5 -0.2 0.7
Loneliness, isolation 0.3 0.5 0.9 -0.1 0.7 -0.7 0.7 0.9 -0.4 -1.0 0.5
Long-standing illness, disability or infirmity 0.3 0.5 1.3 0.6 0.2 0.6 -1.1 -0.8 -0.1 0.5 0.9
Ever had bowel cancer screening 0.5 0.6 1.5 -1.0 0.2 -1.2 0.8 0.6 -0.9 -0.3 -0.8
Diabetes diagnosed by doctor 1.3 2.1 3.5 1.5 -0.7 1.7 -1.7 -1.9 1.3 1.4 0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.8 1.7 -0.8 0.3 -1.2 1.1 0.8 -0.3 -1.3 -0.5
Friendships satisfaction 0.8 1.0 3.4 0.6 1.9 -0.2 -0.5 1.1 0.1 0.8 1.4
Qualifications: nursing, teaching 0.3 0.5 1.5 -0.2 0.9 -0.4 0.1 1.2 -0.4 -1.2 0.4
Commuting to job workplace: Walk 4.2 4.6 8.9 -2.2 -2.4 -2.2 1.8 -1.1 -3.0 -2.3 -1.5
Eye problems/disorders: Cataract 0.4 0.4 0.6 -0.7 -0.5 -0.8 0.7 -0.7 -0.8 -0.4 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.7 1.1 2.9 -1.3 -0.8 -1.0 1.7 -0.4 -0.3 -0.4 -1.4
Medication for cholesterol 0.9 1.3 4.3 0.4 2.0 -0.6 -0.1 2.1 0.9 -0.3 0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.0 2.4 4.4 1.4 1.8 1.5 -0.5 2.0 2.1 1.2 1.2
Back pain experienced in last month 1.1 1.6 3.2 -1.5 -1.2 -0.7 1.8 -0.3 -1.3 -0.5 -1.7
Mineral and other dietary supplements 0.6 0.7 1.7 0.8 -0.7 0.4 -0.8 -1.1 0.8 -0.7 1.3
Breast cancer (self-reported) 0.3 0.4 1.2 -0.2 1.0 -0.5 0.5 1.1 -0.2 0.7 0.2
Asthma (self-reported) 0.7 1.3 2.1 1.4 1.1 1.3 -1.3 -0.0 1.3 0.7 1.4
Osteoporosis (self-reported) 1.0 1.2 3.0 -1.5 0.3 -0.7 1.5 0.7 -1.2 0.2 -1.7
Osteoarthritis (self-reported) 0.6 0.8 1.9 -1.4 -0.4 -0.9 1.1 -0.1 -0.6 -0.4 -1.4
Medication: Aspirin 1.1 1.5 4.6 1.0 -0.0 1.3 -1.2 -0.7 1.0 2.2 1.2
Medication: Gliclazide 0.4 0.5 1.8 -0.2 -1.2 0.2 0.3 -1.4 -0.4 0.4 -0.2
Illnesses of father: None of the above (group 1) 0.3 0.4 1.0 -0.4 0.7 -0.6 0.6 1.0 0.3 -0.6 -0.2
Smoking status: Current 1.9 3.0 6.8 1.9 0.3 1.7 -2.6 -0.4 2.5 1.8 0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.3 3.5 1.5 -0.9 1.5 -1.4 -1.9 1.3 1.7 1.8
Whole body water mass 1.9 10.8 17.1 -3.9 -2.3 -3.8 2.8 -1.0 -4.1 -4.0 -3.2
Leg predicted mass (right) 1.2 6.4 12.0 -2.8 -1.9 -3.0 1.9 -0.8 -3.0 -3.5 -2.3
Arm fat mass (left) 0.2 0.7 3.2 -0.9 0.2 -0.8 0.1 0.6 -1.8 -0.9 -0.2
Number of self-reported non-cancer illnesses 0.1 0.3 1.0 -0.1 0.4 0.3 -0.2 0.3 0.8 1.0 0.2
Average weekly champagne plus white wine intake 0.1 0.1 0.2 -0.2 -0.5 0.3 0.4 -0.4 -0.4 0.2 -0.2
Miserableness 1.5 2.5 6.2 1.5 2.2 0.4 -0.9 2.5 1.4 0.8 1.9
Guilty feelings 2.4 3.7 10.7 -2.0 -0.3 -3.3 1.7 0.9 -1.6 -2.6 -1.3
Wears glasses or contact lenses 0.2 0.2 0.7 0.2 0.1 0.6 0.4 -0.3 0.1 0.8 0.6
Ever taken oral contraceptive pill 0.4 0.4 1.3 -0.7 -0.2 -1.1 0.4 0.4 0.1 -0.9 -0.8
Hearing aid user 0.4 0.5 1.8 -0.7 -0.7 -0.5 0.6 -1.4 0.3 -0.5 -0.5
Mother’s age at death 0.8 1.1 2.1 0.8 1.4 1.0 -0.9 1.1 0.1 1.5 0.9
Financial situation satisfaction 5.3 6.6 8.4 2.7 2.6 2.5 -2.5 1.6 2.6 2.9 2.9
Tinnitus: Yes, now most or all of the time 0.5 0.6 1.4 -0.4 -1.1 -0.2 0.5 -1.2 -0.6 -0.3 -1.0
Commuting to job workplace: Public transport 0.2 0.2 0.9 -0.3 -0.2 -0.7 0.4 -0.2 -0.9 0.0 0.1
Eye problems/disorders: Glaucoma 0.2 0.2 0.6 0.3 0.5 0.1 -0.6 0.2 0.1 0.7 0.7
Medication: Blood pressure 1.3 2.4 6.2 1.4 -0.8 2.5 -1.7 -1.4 0.7 2.1 1.0
Pain type(s) experienced in last month: Hip pain 2.2 2.8 8.6 -1.2 -2.3 -0.8 0.3 -2.9 -0.4 -1.1 -2.1
Supplements: Fish oil (including cod liver oil) 0.2 0.3 0.8 -0.4 0.5 -0.0 0.4 0.2 -0.5 0.8 -0.9
High cholesterol (Self-reported) 0.8 1.4 3.8 0.9 1.1 0.9 -0.7 1.2 1.1 1.9 1.2
Medication: Bendroflumethiazide 0.3 0.4 1.6 0.2 -0.8 1.3 -0.7 -0.4 0.1 0.7 -0.2
Medication: Paracetamol 0.7 1.1 2.1 1.1 1.1 0.6 -1.4 1.1 1.5 0.2 0.6
Medication: Lisinopril 0.1 0.2 0.5 0.2 -0.5 0.4 -0.4 -0.7 -0.5 0.1 0.1
Medication: Atorvastatin 1.4 1.8 3.4 1.5 0.1 1.4 -1.8 -0.4 1.6 1.8 1.0
Illnesses of father: High blood pressure 0.3 0.4 1.7 -0.1 0.4 -0.8 -0.4 1.3 -0.5 -0.2 -0.1
Alcohol drinker status: Never 1.8 2.2 4.7 1.7 0.8 2.2 -1.5 -0.1 1.2 1.6 1.6
Ever smoked 0.1 0.2 0.5 -0.4 -0.4 -0.5 0.4 0.3 -0.1 -0.6 -0.7
Basal metabolic rate 1.6 8.9 14.8 -3.5 -2.1 -3.4 2.4 -1.0 -3.9 -3.8 -2.8
Leg fat percentage (left) 0.1 0.3 1.1 -0.2 0.4 0.5 -0.6 0.6 -1.1 0.2 0.6
Arm fat-free mass (left) 2.0 10.2 17.5 -3.9 -2.0 -3.5 2.8 -0.8 -4.2 -3.7 -3.2
Number of operations (self-reported) 0.8 1.2 2.3 -1.5 -1.1 -1.3 0.7 -0.2 -0.8 -1.3 -1.1
Average weekly beer plus cider intake 0.2 0.2 0.7 0.3 -0.8 0.3 -0.1 -0.5 0.7 0.4 -0.1
Irritability 0.8 1.3 2.8 -1.3 -0.2 -1.7 1.6 0.1 -0.8 -1.2 -1.0
Risk taking 0.5 0.7 1.5 1.0 -0.7 0.9 -0.9 -0.9 0.6 -0.1 1.2
Ever had prostate specific antigen (PSA) test 0.3 0.4 1.1 -0.4 0.4 -0.5 0.3 1.0 -0.9 -0.1 0.4
Fractured/broken bones in last 5 years 0.9 1.2 2.9 -1.0 -1.7 -0.5 0.6 -1.6 -1.2 -0.6 -0.9
Age started oral contraceptive pill 1.9 2.3 5.3 1.4 1.8 1.5 -1.1 0.8 1.4 2.3 1.5
Diastolic blood pressure, automated reading 0.2 0.5 1.9 -0.7 0.2 0.7 0.1 0.1 -0.1 1.4 -1.1
Ever depressed for a whole week 1.0 1.2 2.2 1.2 0.4 1.2 -1.4 0.2 0.7 1.3 1.5
Unable to work because of sickness or disability 0.2 0.2 1.2 0.3 -0.3 -0.0 0.0 -0.2 -0.2 -1.1 0.4
Commuting to job workplace: Cycle 0.2 0.3 0.9 0.2 0.7 0.2 0.6 0.9 -0.2 0.7 0.2
Myopia 0.6 0.9 2.5 -0.1 1.6 -0.7 0.7 1.5 -0.1 1.3 0.0
Vascular/heart problems diagnosed by doctor 0.6 1.7 7.6 -0.6 -0.3 -1.8 1.1 0.0 -0.8 -2.8 -0.1
Cholesterol lowering medication 0.7 1.1 4.8 -0.3 -1.7 0.2 0.1 -2.2 -0.4 -0.4 -0.8
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 0.9 -0.6 -0.6 -0.9 0.6 0.1 -0.5 -0.3 -0.1
Pain experienced in last month 3.7 6.2 10.1 2.8 2.3 2.6 -2.1 1.6 2.5 2.5 3.2
Supplements: Calcium 0.8 0.9 2.7 -0.9 -1.5 -0.1 0.6 -1.1 -0.3 -0.3 -1.6
Basal cell carcinoma (self-reported) 0.8 0.9 3.9 0.0 -2.0 0.8 -0.8 -1.3 0.6 0.2 -0.5
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.6 0.3 -0.6 0.9 -0.5 -1.0 0.4 1.2 -0.0
Deep venous thrombosis (DVT) (self-reported) 0.5 0.7 2.5 -0.4 -1.6 -0.7 -0.6 -1.2 -0.0 -0.7 -0.3
Heart disease (siblings) 1.2 1.5 2.0 -1.4 -1.4 -1.4 0.7 -1.0 -1.2 -1.1 -1.4
Alcohol drinker status: Previous 1.2 1.3 2.9 -0.7 -1.7 -1.0 0.2 -1.3 -1.0 -1.7 -0.8
Pack years of smoking 1.9 2.8 5.3 2.2 0.2 1.8 -2.2 -0.4 2.3 0.9 1.8
Impedance of whole body 1.0 4.9 9.5 2.9 1.1 2.4 -2.3 -0.2 3.1 1.6 2.7
Leg fat mass (left) 0.2 0.9 4.0 -1.0 0.0 -0.7 0.1 0.5 -2.0 -1.1 -0.3
Arm predicted mass (left) 2.1 10.5 17.6 -4.0 -2.2 -3.6 2.8 -0.8 -4.2 -3.8 -3.3