TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
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Lung FEV1/FVC ratio
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chr17:1,717,695-2,453,908
Best TWAS P=2.52e-21 · Best GWAS P=4.91e-19 conditioned to 0.00348
1.7M
1.8M
1.9M
2M
2.1M
2.2M
2.3M
2.4M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
SMG6
0.08
0.05
blup
144
0.07
0.00013
-7.6
-9.5
2.5e-21
-0.73
0.09
0.85
TRUE
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
SMG6
0.03
0.01
blup
144
0.01
0.00478
-6.3
-9.2
2.2e-20
-0.65
0.16
0.34
FALSE