Best TWAS P=2.52e-21 · Best GWAS P=4.91e-19 conditioned to 0.00348
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SMG6 | 0.03 | 0.01 | blup | 144 | 0.01 | 0.00478 | -6.3 | -9.2 | 2.2e-20 | -0.65 | 0.16 | 0.34 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SMG6 | 0.08 | 0.05 | blup | 144 | 0.07 | 0.00013 | -7.6 | -9.5 | 2.5e-21 | -0.73 | 0.09 | 0.85 | TRUE |