[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr20:60,064,969-61,679,007

Best TWAS P=5.08e-17 · Best GWAS P=3.27e-15 conditioned to 2.65e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
16	The Cancer Genome Atlas	Lung Adenocarcinoma	CABLES2	0.10	0.07	enet	16	0.08	2.8e-09	4.16	8.4	5.1e-17	-0.25	0.99	0.01	TRUE
4	GTEx	Cells Transformed fibroblasts	RP11-157P1.5	0.15	0.12	enet	15	0.10	7.3e-08	3.37	-5.4	7.8e-08	0.17	0.99	0.00	TRUE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CABLES2	0.12	0.03	enet	19	0.07	2.3e-08	4.16	8.3	1.1e-16	-0.24	0.83	0.12	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	CABLES2	0.09	0.04	enet	10	0.07	4.5e-08	-5.93	7.3	2.3e-13	-0.41	0.81	0.18	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CABLES2	0.06	0.00	blup	79	0.02	3.7e-03	-0.71	6.8	1.2e-11	-0.21	0.03	0.13	FALSE
10	METSIM	Adipose	CABLES2	0.16	0.14	lasso	8	0.15	8.6e-22	-5.93	6.5	1.0e-10	-0.28	0.97	0.03	FALSE
8	GTEx	Prostate	CABLES2	0.31	0.10	lasso	8	0.14	2.1e-04	-5.93	6.2	5.8e-10	-0.22	0.12	0.06	FALSE
11	YFS	Blood	CABLES2	0.03	0.03	lasso	6	0.02	2.0e-08	6.74	6.0	1.9e-09	-0.36	0.26	0.74	FALSE
6	GTEx	Heart Left Ventricle	CABLES2	0.19	0.20	lasso	5	0.18	3.8e-10	-5.93	5.8	7.3e-09	-0.28	1.00	0.00	FALSE
2	GTEx	Artery Aorta	CABLES2	0.26	0.09	enet	28	0.16	3.6e-09	-2.88	5.7	9.0e-09	-0.20	0.99	0.00	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GATA5	0.04	0.01	blup	33	0.02	3.1e-03	-0.52	5.6	2.4e-08	-0.48	0.03	0.17	FALSE
9	GTEx	Thyroid	CABLES2	0.38	0.08	enet	34	0.19	3.0e-14	4.16	5.6	2.5e-08	-0.28	1.00	0.00	FALSE
7	GTEx	Nerve Tibial	CABLES2	0.30	0.15	enet	52	0.22	2.4e-15	-5.93	5.4	6.2e-08	-0.23	0.99	0.01	FALSE
3	GTEx	Artery Tibial	MTG2	0.37	0.12	enet	45	0.12	1.9e-09	-4.37	5.2	1.9e-07	-0.20	1.00	0.00	FALSE
5	GTEx	Colon Sigmoid	CABLES2	0.29	0.08	lasso	11	0.08	6.3e-04	-5.93	5.2	2.2e-07	-0.19	0.46	0.06	FALSE
1	GTEx	Adipose Subcutaneous	CABLES2	0.17	0.11	enet	11	0.14	2.3e-11	-3.07	5.2	2.6e-07	-0.27	0.95	0.05	FALSE