Best TWAS P=3.79e-10 · Best GWAS P=2.49e-10 conditioned to 1.69e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Lung | BTG3 | 0.17 | 0.16 | lasso | 3 | 0.18 | 1.1e-13 | -5.6 | 6.3 | 3.8e-10 | -0.19 | 0.02 | 0.98 | TRUE |
2 | METSIM | Adipose | BTG3 | 0.09 | 0.05 | lasso | 3 | 0.05 | 1.6e-08 | -6.1 | 6.1 | 9.0e-10 | -0.19 | 0.01 | 0.99 | FALSE |