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Lung FEV1/FVC ratio
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chr21:18,271,223-19,680,363
Best TWAS P=3.79e-10 · Best GWAS P=2.49e-10 conditioned to 1.69e-07
18.2M
18.4M
18.6M
18.8M
19M
19.2M
19.4M
19.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Lung
BTG3
0.17
0.16
lasso
3
0.18
1.1e-13
-5.6
6.3
3.8e-10
-0.19
0.02
0.98
TRUE
2
METSIM
Adipose
BTG3
0.09
0.05
lasso
3
0.05
1.6e-08
-6.1
6.1
9.0e-10
-0.19
0.01
0.99
FALSE