Best TWAS P=6.2e-09 · Best GWAS P=2.3e-10 conditioned to 0.157
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | ADAMTS5 | 0.13 | 0.00 | lasso | 7 | 0.02 | 0.0072 | -2.8 | -5.2 | 1.7e-07 | -0.33 | 0.20 | 0.28 | TRUE |
| 2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | ADAMTS5 | 0.11 | 0.05 | blup | 95 | 0.04 | 0.0156 | 6.1 | -5.8 | 6.2e-09 | -0.92 | 0.02 | 0.82 | TRUE |