TWAS hub - BTG3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Lung	0.1699	0.0477	3.6e-05	0.157	NA	0.150	NA	0.179	4.8e-12	NA	1.5e-11	NA	1.1e-13
2	METSIM	Adipose	0.0874	0.0264	5.5e-05	0.055	0.02	0.052	0.039	0.054	1.3e-08	0.00052	3.1e-08	1.3e-06	1.6e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Fluid intelligence score	11.7	24.3	27.2	-4.6	-5.2
Verbal and Numeric Reasoning (VNR)	10.3	24.7	27.0	-4.7	-5.2
Neuroticism (Nagel 2018)	10.1	23.7	24.4	4.8	4.9
Stomach or abdominal pain in last month	9.7	12.1	13.3	3.3	3.6
Neuroticism	9.0	21.7	22.6	4.5	4.8
Sensitivity / hurt feelings	8.7	14.9	15.1	3.8	3.9
Intelligence (Savage-Jansen 2018)	8.4	25.7	26.9	-4.9	-5.2
Medication: Omeprazole (e.g. Zanprol)	7.7	9.4	10.5	3.2	2.9
Lung FEV1/FVC ratio	7.6	38.4	39.2	6.3	6.1
Worry (Nagel 2018)	7.5	15.9	17.1	3.8	4.1
Medication: Omeprazole	7.4	8.8	9.9	3.1	2.8
Neuroticism score	6.5	13.6	14.2	3.6	3.8
Depressed Affect (Nagel 2018)	6.2	13.0	14.0	3.5	3.7
Mean Putamen Volume	5.8	6.7	6.7	2.6	2.6
Loneliness, isolation	5.7	7.9	8.9	2.6	3.0
HbA1C	5.4	6.0	6.1	2.4	2.5
Hearing difficulty/problems with background noise	5.4	8.6	8.9	2.9	3.0
Townsend deprivation index at recruitment	5.1	7.1	8.0	-2.5	-2.8
Number of live births	4.9	7.0	7.1	2.6	2.7
Nervous feelings	4.2	7.8	8.8	2.6	3.0
Overall health rating	4.2	9.0	9.5	3.1	2.9
Major Depression (MDD)	4.1	5.0	5.1	2.2	2.2
Prospective memory result	4.0	4.9	5.3	2.3	2.1
Forced vital capacity (FVC)	3.9	15.1	15.6	-3.8	-3.9
Worrier / anxious feelings	3.9	7.4	8.7	2.5	3.0
Worry too long after embarrassment	3.9	6.6	6.7	2.6	2.5
Qualifications: nursing, teaching	3.7	5.8	6.1	-2.5	-2.3
Lung FVC	3.5	17.7	19.1	-4.0	-4.4
Miserableness	3.5	6.0	6.1	2.4	2.5
Forced vital capacity (FVC), Best measure	3.3	12.2	13.1	-3.4	-3.6
Alcohol drinker status: Never	3.3	3.9	4.2	1.9	2.0
Fractured/broken bones in last 5 years	3.3	4.3	4.4	2.1	2.0
Diverticular disease/diverticulitis (self-reported)	3.2	3.8	3.9	2.0	1.9
Tense / ‘highly strung’	3.2	5.4	5.9	2.4	2.2
Basal cell carcinoma (self-reported)	3.2	3.8	3.9	-1.9	-2.0
Qualifications: NVQ or HND or HNC or equivalent	3.1	3.7	4.0	1.8	2.0
Frequency of tiredness / lethargy in last 2 weeks	3.0	4.9	4.9	2.2	2.2
Heart attack	2.9	3.7	3.8	-1.9	-1.9
Pain all over the body in last month	2.9	3.1	3.3	-1.7	-1.8
Commuting to job workplace: Walk	2.9	3.1	3.3	1.7	1.8
Medication: Atorvastatin	2.9	3.5	3.9	2.0	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.8	5.9	6.5	-2.3	-2.6
Severe depression (siblings)	2.7	3.0	3.3	-1.8	-1.7
Medication: Cholesterol lowering	2.6	4.1	4.6	-1.9	-2.1
Comparative body size at age 10	2.6	7.1	8.5	-2.4	-2.9
Knee pain experienced in last month	2.6	4.0	4.2	2.0	2.0
Guilty feelings	2.6	3.9	4.2	1.9	2.1
Supplements: Fish oil (including cod liver oil)	2.6	3.4	3.6	-1.9	-1.8
Alzheimer’s Disease (in father)	2.4	2.6	3.0	-1.5	-1.7
Ever unenthusiastic/disinterested for a whole week	2.4	2.9	3.4	1.6	1.8
Health satisfaction	2.3	3.0	3.5	1.9	1.6
Heart attack/myocardial infarction (self-reported)	2.3	3.0	3.1	-1.8	-1.7
Depression (Nagel 2018)	2.2	3.3	3.5	1.8	1.9
Allergy or Eczema	2.2	5.8	6.2	2.3	2.5
Length of working week for main job	2.2	2.4	2.7	-1.4	-1.7
Mineral and other dietary supplements	2.2	3.0	3.4	1.8	1.6
Crohns Disease (2017)	2.1	4.7	4.9	-2.2	-2.1
Systolic Blood Pressure	2.1	10.4	10.6	-3.2	-3.3
Frequency of tenseness / restlessness in last 2 weeks	2.1	3.3	3.5	1.9	1.8
Financial difficulties in last 2 years	2.1	2.8	3.0	1.7	1.6
Medication: Aspirin	2.1	2.7	2.9	-1.6	-1.7
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	2.7	1.6	1.7
Medication: Simvastatin	2.0	2.9	3.1	-1.6	-1.7
Birth weight	2.0	4.4	4.6	-2.1	-2.1
Number of full brothers	2.0	2.5	2.7	1.5	1.6
Wheeze or whistling in the chest in last year	2.0	3.7	4.0	1.8	2.0
Leg pain on walking	2.0	2.5	2.7	1.6	1.5
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	2.4	-1.3	-1.6
Qualifications: College or University degree	1.9	5.9	6.0	-2.4	-2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	2.3	1.5	1.5
Ever depressed for a whole week	1.9	2.3	2.6	1.4	1.6
Hearing difficulty/problems: Yes	1.8	2.7	3.0	1.7	1.6
Medication: Atenolol	1.8	2.2	2.4	-1.4	-1.6
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.2	2.3	1.4	1.5
Suffer from ‘nerves’	1.8	2.8	2.8	1.7	1.7
Mood swings	1.8	3.2	3.4	1.8	1.7
Hayfever, allergic rhinitis or eczema	1.7	3.6	3.7	1.9	1.9
Medication: Levothyroxine sodium	1.7	2.9	3.4	1.8	1.6
Headache pain in last month	1.7	2.9	3.3	1.6	1.8
Osteoarthritis (self-reported)	1.7	2.2	2.4	1.5	1.5
Impedance of arm (left)	1.6	7.3	8.0	-2.6	-2.8
Medication for pain relief, constipation, heartburn	1.6	2.7	3.0	-1.7	-1.5
Medication: Seretide 50 evohaler	1.6	1.9	2.2	1.5	1.2
Smoking status: Previous	1.6	2.4	2.4	-1.6	-1.5
Pain experienced in last month	1.6	2.7	3.2	-1.5	-1.8
Cardiovascular Disease	1.5	4.9	5.2	-2.3	-2.1
Allergy	1.5	3.6	3.8	-1.8	-2.0
Impedance of arm (right)	1.5	7.1	7.7	-2.6	-2.8
Shortness of breath walking on level ground	1.5	1.8	1.9	1.4	1.3
Medication: Aspirin	1.5	1.9	2.3	-1.3	-1.5
Ever had prostate specific antigen (PSA) test	1.5	1.8	1.9	-1.4	-1.3
Prostate Cancer	1.4	1.9	2.4	1.2	1.6
Crohns Disease (2012)	1.4	2.3	2.4	-1.5	-1.5
Neuroticism (2016)	1.4	2.0	2.2	1.5	1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.4	1.8	-1.0	-1.3
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	2.8	1.7	1.2
Medication: Lisinopril	1.4	1.8	1.9	-1.4	-1.3
Number of operations (self-reported)	1.4	2.1	2.2	1.4	1.5
Qualifications: None of the above	1.3	2.7	3.1	1.5	1.8
Depression (self-reported)	1.3	1.5	1.9	1.1	1.4
Medication: Paracetamol	1.3	2.2	2.3	1.5	1.4
Number of children fathered	1.3	1.5	1.7	-1.3	-1.1
Migraine (self-reported)	1.3	1.7	1.7	-1.3	-1.3
Unable to work because of sickness or disability	1.3	1.7	1.8	1.3	1.3
Body mass index (BMI)	1.2	5.2	5.3	2.3	2.3
Waist circumference	1.2	4.5	4.5	2.1	2.1
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	1.7	1.3	1.3
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	1.7	1.1	1.3
Medication: Blood pressure	1.2	2.0	2.4	-1.3	-1.6
Impedance of whole body	1.2	6.1	6.5	-2.4	-2.6
Reaction Time	1.1	2.1	2.4	1.4	1.5
Chronotype (morning person)	1.1	2.6	2.7	-1.6	-1.6
Chest pain or discomfort	1.1	1.5	1.6	1.2	1.3
Supplements: Calcium	1.1	1.2	1.5	-1.0	-1.2
Fasting Glucose	1.0	1.2	1.3	1.0	1.1
Lupus	1.0	1.6	1.8	1.3	1.2
Had menopause	1.0	1.3	1.3	1.2	1.1
Qualifications: A levels/AS levels or equivalent	1.0	2.2	2.6	-1.3	-1.6
Standing height	1.0	10.2	10.4	-3.2	-3.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	1.6	1.2	1.3
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	1.8	-1.1	-1.4
Leg fat percentage (right)	1.0	3.8	3.8	1.9	1.9
Neck or shoulder pain in last month	1.0	1.5	1.6	1.2	1.3
Irritable Bowel Disease (IBD)	0.9	2.2	2.5	-1.6	-1.4
BMI	0.9	5.4	5.9	2.2	2.4
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	2.1	1.4	1.4
High blood pressure (mother)	0.9	1.3	1.4	-1.0	-1.2
Number of incorrect matches in round	0.9	1.4	1.6	1.1	1.3
Mouth/teeth dental problems	0.9	1.4	1.8	-1.4	-1.0
Forced expiratory volume in 1-second (FEV1)	0.9	3.2	3.3	-1.7	-1.8
Hair/balding pattern: Pattern 4	0.9	2.2	2.3	-1.5	-1.4
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	2.0	1.1	1.4
Supplements: Vitamin C	0.9	1.1	1.4	-1.2	-0.9
Wears glasses or contact lenses	0.9	1.0	1.0	1.0	1.0
Age at First Birth	0.8	1.2	1.4	-1.0	-1.2
Type 2 Diabetes (T2D) (2018)	0.8	1.5	1.7	-1.2	-1.3
Supplements: Zinc	0.8	0.9	0.9	-0.9	-1.0
Serious illness, injury or assault to yourself	0.8	1.0	1.0	1.0	1.0
Father’s age at death	0.8	1.1	1.3	-0.9	-1.1
Leg fat mass (right)	0.8	3.1	3.1	1.8	1.7
Comparative height size at age 10	0.8	4.5	4.8	-2.0	-2.2
Illnesses of siblings: Diabetes	0.8	1.0	1.1	0.9	1.0
Ever had bowel cancer screening	0.8	1.0	1.0	-1.0	-1.0
Leg fat percentage (left)	0.8	2.7	2.8	1.6	1.7
Vascular/heart problems diagnosed by doctor	0.8	2.1	2.4	1.3	1.6
Pack years adult smoking proportion	0.7	1.0	1.1	1.1	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.0	0.9	1.0
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	0.8	-0.9	-0.9
Sitting height	0.7	5.1	5.1	-2.2	-2.2
Impedance of leg (left)	0.7	3.4	3.4	-1.9	-1.8
Past tobacco smoking	0.7	1.4	1.5	1.1	1.2
Happiness	0.7	0.9	0.9	-1.0	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	2.6	-1.4	-1.6
Pulse wave Arterial Stiffness index	0.7	0.8	0.8	-0.9	-0.9
Emphysema/chronic bronchitis	0.7	0.8	0.9	-0.9	-0.8
Medication: Ibuprofen	0.7	0.8	0.9	0.9	1.0
Medication: Allopurinol	0.7	1.0	1.0	-1.0	-0.9
Family relationship satisfaction	0.7	0.9	0.9	1.0	0.9
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	0.9	-0.9	-0.9
Back pain experienced in last month	0.7	1.1	1.2	1.1	1.0
Medication: Paracetamol	0.7	1.1	1.3	1.1	0.9
Illnesses of father: High blood pressure	0.7	0.9	1.0	1.0	0.9
Leg fat mass (left)	0.7	2.5	2.6	1.6	1.6
Alzheimer’s Disease (in mother)	0.6	0.7	0.8	0.9	0.8
Ulcerative Colitis (UC)	0.6	1.1	1.2	-1.1	-0.9
Blood White Count	0.6	4.4	4.5	-2.1	-2.1
Taking other prescription medications	0.6	0.9	0.9	0.9	0.9
Age when periods started (menarche)	0.6	1.3	1.6	1.0	1.3
Qualifications: CSEs or equivalent	0.6	0.8	1.1	0.7	1.1
High blood pressure	0.6	1.8	2.1	-1.2	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	1.6	1.2	1.1
Peak expiratory flow (PEF)	0.6	1.3	1.5	-1.1	-1.2
Illnesses of father: Heart disease	0.6	0.8	0.9	1.0	0.9
Average weekly red wine intake	0.6	0.9	1.0	1.0	0.9
Friendships satisfaction	0.6	0.8	0.9	0.9	0.8
Medication: Gliclazide	0.6	0.7	0.8	0.8	0.9
Diastolic blood pressure, automated reading	0.6	1.9	2.1	-1.5	-1.3
Coronary Artery Disease (CAD)	0.5	0.6	0.7	0.8	0.8
HDL Cholesterol	0.5	0.9	1.0	1.0	0.9
Heel T-Score	0.5	4.4	4.9	-2.0	-2.2
Number of treatments/medications taken	0.5	0.8	0.9	0.9	0.9
Ever used hormone-replacement therapy (HRT)	0.5	0.7	0.8	0.9	0.8
Ever had hysterectomy (womb removed)	0.5	0.5	0.6	0.7	0.7
Systolic blood pressure, automated reading	0.5	1.5	1.6	-1.3	-1.2
Arm fat percentage (right)	0.5	1.8	1.9	1.4	1.3
Pulse rate	0.5	0.9	1.2	-0.7	-1.1
Mouth/teeth dental problems: Dentures	0.5	0.9	1.1	1.0	0.9
Age at first live birth	0.5	0.8	1.1	-1.1	-0.7
Mean time to correctly identify matches	0.5	1.0	1.1	0.9	1.1
Arm fat mass (left)	0.5	1.9	2.0	1.4	1.4
Average weekly champagne plus white wine intake	0.5	0.7	0.8	-0.8	-0.9
Age started oral contraceptive pill	0.5	0.6	0.7	-0.8	-0.7
Myopia	0.5	0.7	0.7	-0.8	-0.9
Schizophrenia (2014)	0.4	1.0	1.2	0.9	1.1
Type 2 Diabetes (T2D) (2012)	0.4	0.4	0.5	-0.7	-0.6
Impedance of leg (right)	0.4	1.8	1.8	-1.3	-1.4
Diabetes (self-reported)	0.4	0.7	0.9	-0.7	-0.9
Arm fat mass (right)	0.4	1.7	1.7	1.3	1.3
Ever highly irritable/argumentative for 2 days	0.4	0.4	0.5	-0.7	-0.6
Loud music exposure frequency	0.4	0.4	0.4	0.7	0.6
Gout (self-reported)	0.4	0.6	0.7	-0.8	-0.7
Body fat percentage	0.4	1.7	1.9	1.4	1.3
Pulse wave peak to peak time	0.4	0.5	0.5	0.7	0.7
Diabetes diagnosed by doctor	0.4	0.7	1.0	-0.7	-1.0
Number of self-reported non-cancer illnesses	0.4	0.8	0.8	0.9	0.9
Commuting to job workplace: Public transport	0.4	0.5	0.6	-0.6	-0.8
High cholesterol (Self-reported)	0.4	0.8	0.8	-0.8	-0.9
Pack years of smoking	0.4	0.5	0.6	0.8	0.7
Bipolar Disorder or Schizophrenia	0.3	0.6	0.9	0.7	0.9
Triglycerides	0.3	0.4	0.6	-0.8	-0.5
Height	0.3	5.0	5.4	-2.1	-2.3
Frequency of depressed mood in last 2 weeks	0.3	0.5	0.5	0.7	0.7
Diabetes (father)	0.3	0.3	0.4	0.6	0.5
Medication: Ramipril	0.3	0.4	0.5	-0.6	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.5	-0.5	-0.7
Illnesses of mother	0.3	0.4	0.7	0.4	0.8
Medication: Amlodipine	0.3	0.4	0.5	-0.5	-0.7
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.5	0.6	0.7
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.3	0.6	0.6
Hypertension (Self-reported)	0.3	0.9	1.1	-0.8	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	0.6	0.7	0.8
Arm fat percentage (left)	0.3	1.3	1.5	1.2	1.1
Illnesses of father: None of the above (group 1)	0.3	0.3	0.6	0.3	0.8
Ever taken oral contraceptive pill	0.3	0.4	0.4	-0.6	-0.6
Mother’s age at death	0.3	0.4	0.4	-0.6	-0.7
Medication: Blood pressure	0.3	0.6	0.8	0.9	0.6
Bipolar Disorder (2018)	0.2	0.3	0.4	0.4	0.6
Schizophrenia (2018)	0.2	0.4	0.5	0.5	0.7
Breast Cancer	0.2	0.4	0.4	-0.6	-0.6
Primary Biliary Cirrhosis	0.2	0.2	0.3	0.6	0.4
Blood Platelet Count	0.2	2.4	2.4	-1.6	-1.5
Smoking Status	0.2	0.4	0.4	-0.7	-0.7
Hypothyroidism (self reported)	0.2	0.5	0.6	0.8	0.6
Trunk fat percentage	0.2	0.8	1.0	1.0	0.8
Supplements: Glucosamine	0.2	0.3	0.4	-0.6	-0.4
Weight	0.2	0.7	0.8	0.9	0.9
Hip circumference	0.2	0.7	0.8	0.9	0.8
Alcohol intake versus 10 years previously	0.2	0.3	0.3	-0.6	-0.5
Asthma	0.2	0.4	0.4	0.6	0.7
Pulse wave reflection index	0.2	0.2	0.3	-0.6	-0.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.4	-0.6	-0.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.5	0.7	0.5
High blood pressure (siblings)	0.2	0.3	0.3	-0.5	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.3	-0.5	-0.5
Whole body fat mass	0.2	1.0	1.1	1.0	0.9
Had major operations	0.2	0.2	0.2	0.5	0.5
Eye problems/disorders: Cataract	0.2	0.2	0.3	0.6	0.4
Breast cancer (self-reported)	0.2	0.3	0.3	0.5	0.6
Hearing aid user	0.2	0.3	0.4	0.6	0.3
Commuting to job workplace: Cycle	0.2	0.2	0.4	-0.6	-0.3
Arm predicted mass (left)	0.2	0.9	1.1	0.9	1.0
Schizophrenia vs Biploar Disorder	0.1	0.1	0.1	0.3	0.4
LDL Cholesterol	0.1	0.1	0.2	-0.4	-0.3
Rheumatoid Arthritis	0.1	0.1	0.1	0.3	0.2
Blood Red Count	0.1	0.7	0.9	-0.8	-0.9
Respiratory disease	0.1	0.2	0.2	-0.4	-0.4
Tanning	0.1	1.2	1.3	-1.0	-1.1
Relative age of first facial hair	0.1	0.3	0.3	-0.5	-0.6
Medication for hormone replacement therapy	0.1	0.1	0.1	0.3	0.3
Vitamin and mineral supplements	0.1	0.1	0.2	0.4	0.2
Medication: Metformin	0.1	0.1	0.2	0.4	0.2
Leg fat-free mass (left)	0.1	0.6	0.6	0.8	0.7
Relative age voice broke	0.1	0.2	0.3	-0.5	-0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.2	0.3	-0.5	-0.2
Multivitamins +/- minerals	0.1	0.1	0.2	-0.4	-0.2
Chronic bronchitis/emphysema (father)	0.1	0.1	0.1	-0.2	-0.4
Leg predicted mass (left)	0.1	0.6	0.6	0.8	0.7
Trunk fat mass	0.1	0.3	0.3	0.6	0.4
Illnesses of siblings	0.1	0.1	0.1	-0.4	-0.2
Time employed in main current job	0.1	0.1	0.1	0.1	0.3
Falls in the last year	0.1	0.1	0.1	0.3	0.3
Medication: Lansoprazole	0.1	0.1	0.2	0.4	0.4
Breastfed as a baby	0.1	0.1	0.2	0.4	0.2
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.1	-0.4	-0.3
Arm fat-free mass (right)	0.1	0.4	0.5	0.6	0.7
Exposure to tobacco smoke outside home	0.1	0.1	0.2	-0.4	-0.1
Heart disease (mother)	0.1	0.1	0.1	0.4	0.3
Arm predicted mass (right)	0.1	0.3	0.3	0.5	0.6
Number of full sisters	0.1	0.2	0.2	-0.4	-0.4
Leg fat-free mass (right)	0.1	0.3	0.3	0.6	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.2	-0.2	-0.4
Asthma (self-reported)	0.1	0.2	0.2	0.4	0.5
Leg predicted mass (right)	0.1	0.3	0.3	0.6	0.5
Financial situation satisfaction	0.1	0.1	0.1	0.4	0.1
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	-0.4	0.0
Arm fat-free mass (left)	0.1	0.7	0.7	0.8	0.9
Risk taking	0.1	0.1	0.1	0.3	0.3
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.1	-0.3	-0.3
Heart disease (siblings)	0.1	0.1	0.2	0.4	0.2
Alcohol drinker status: Previous	0.1	0.1	0.2	0.3	0.5
Alzheimer’s Disease (including proxy)	0.0	0.0	0.1	0.0	-0.2
Ovarian Cancer	0.0	0.0	0.1	-0.1	-0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	-0.2	-0.1
Body Mass Index (BMI) (2010)	0.0	0.0	0.1	-0.3	-0.1
Ulcerative Colitis	0.0	0.0	0.0	-0.1	-0.1
Blood Eosinophil Count	0.0	0.2	0.2	-0.5	-0.5
Waist Hip Ratio (WHR)	0.0	0.1	0.2	0.1	0.4
Hair Pigment	0.0	0.6	0.7	0.8	0.7
Hand grip strength (left)	0.0	0.0	0.0	-0.1	-0.1
Average weekly spirits intake	0.0	0.0	0.1	0.2	0.1
Angina	0.0	0.0	0.1	0.0	0.2
Medication: Co-codamol	0.0	0.0	0.0	-0.1	0.1
Diabetes (mother)	0.0	0.0	0.0	0.2	0.2
Hand grip strength (right)	0.0	0.0	0.0	-0.0	0.0
Current tobacco smoking	0.0	0.0	0.0	0.1	-0.1
Average weekly fortified wine intake	0.0	0.0	0.0	0.2	0.0
Maternal smoking around birth	0.0	0.1	0.1	0.3	0.2
Fed-up feelings	0.0	0.1	0.1	0.3	0.3
Alcohol usually taken with meals	0.0	0.0	0.1	0.1	0.3
Hair/balding pattern: Pattern 2	0.0	0.0	0.1	-0.1	-0.2
Had other major operations	0.0	0.0	0.1	0.0	0.2
Trunk fat-free mass	0.0	0.2	0.2	-0.5	-0.3
Hair/balding pattern: Pattern 3	0.0	0.0	0.1	-0.3	-0.1
Noisy workplace	0.0	0.0	0.0	-0.1	0.2
Lung cancer (father)	0.0	0.0	0.0	-0.2	0.0
Trunk predicted mass	0.0	0.1	0.2	-0.4	-0.3
Exposure to tobacco smoke at home	0.0	0.0	0.0	0.1	0.2
Birth weight of first child	0.0	0.0	0.0	0.2	0.0
Blood clot in the leg (DVT)	0.0	0.0	0.0	0.1	0.1
Glaucoma (self-reported)	0.0	0.0	0.0	-0.2	0.1
Eye problems/disorders: None of the above	0.0	0.0	0.1	-0.2	-0.0
Mouth/teeth dental problems: Loose teeth	0.0	0.0	0.0	-0.2	0.0
Angina (self-reported)	0.0	0.0	0.0	0.0	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.1	-0.1	-0.2
Pulse rate, automated reading	0.0	0.1	0.2	-0.2	-0.4
Alcohol intake frequency.	0.0	0.0	0.1	0.2	0.2
Age at last live birth	0.0	0.0	0.1	0.1	0.3
Whole body fat-free mass	0.0	0.0	0.0	0.2	0.2
Handedness (chirality/laterality): Left-handed	0.0	0.1	0.1	-0.2	-0.3
Long-standing illness, disability or infirmity	0.0	0.0	0.0	-0.0	-0.2
Medication for cholesterol	0.0	0.0	0.1	0.0	0.2
Osteoporosis (self-reported)	0.0	0.0	0.1	-0.2	-0.0
Smoking status: Current	0.0	0.0	0.0	0.2	-0.0
Whole body water mass	0.0	0.0	0.0	0.1	0.1
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.0	-0.2	-0.1
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.0	0.2	0.1
Medication: Bendroflumethiazide	0.0	0.1	0.1	0.3	-0.1
Ever smoked	0.0	0.1	0.1	-0.1	-0.3
Basal metabolic rate	0.0	0.3	0.3	0.5	0.5
Average weekly beer plus cider intake	0.0	0.0	0.0	0.1	-0.1
Irritability	0.0	0.0	0.1	0.2	0.2
Cholesterol lowering medication	0.0	0.1	0.1	0.3	0.2

Hub : Genes

BTG3

Models

Trait associations