Best TWAS P=1.58e-21 · Best GWAS P=7.58e-37 conditioned to 1.88e-34
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | MRPS6 | 0.10 | 0.04 | enet | 4 | 0.00 | 1.2e-01 | -9.7 | -9.5 | 1.6e-21 | -0.02 | 0.11 | 0.08 | TRUE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | CLIC6 | 0.24 | 0.25 | lasso | 3 | 0.24 | 3.4e-09 | 5.2 | 5.4 | 6.0e-08 | -0.03 | 0.98 | 0.00 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | LINC00649 | 0.14 | 0.01 | enet | 14 | 0.03 | 5.5e-03 | -2.1 | -5.3 | 9.0e-08 | -0.34 | 0.13 | 0.36 | TRUE |
| 4 | METSIM | Adipose | LINC00310 | 0.05 | 0.01 | enet | 19 | 0.03 | 8.4e-06 | 1.6 | 5.7 | 1.5e-08 | -0.03 | 0.26 | 0.02 | TRUE |