[Hub]/) : Traits : Lung FEV1/FVC ratio :

chr21:34,589,270-36,786,042

Best TWAS P=1.58e-21 · Best GWAS P=7.58e-37 conditioned to 1.88e-34

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial MRPS6 0.10 0.04 enet 4 0.00 1.2e-01 -9.7 -9.5 1.6e-21 -0.02 0.11 0.08 TRUE
2 GTEx Esophagus Gastroesophageal Junction CLIC6 0.24 0.25 lasso 3 0.24 3.4e-09 5.2 5.4 6.0e-08 -0.03 0.98 0.00 TRUE
3 GTEx Skin Not Sun Exposed Suprapubic LINC00649 0.14 0.01 enet 14 0.03 5.5e-03 -2.1 -5.3 9.0e-08 -0.34 0.13 0.36 TRUE
4 METSIM Adipose LINC00310 0.05 0.01 enet 19 0.03 8.4e-06 1.6 5.7 1.5e-08 -0.03 0.26 0.02 TRUE