Best TWAS P=1.17e-26 · Best GWAS P=3.66e-27 conditioned to 0.000918
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | MICAL3 | 0.23 | 0.06 | lasso | 4 | 0.03 | 2.7e-02 | 9.3 | -10.0 | 1.7e-23 | 0.63 | 0.05 | 0.66 | FALSE |
| 2 | GTEx | Thyroid | MICAL3 | 0.18 | 0.13 | enet | 18 | 0.13 | 6.5e-10 | -10.7 | -10.7 | 1.2e-26 | 0.84 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MICAL3 | 0.10 | 0.06 | enet | 14 | 0.04 | 1.5e-03 | 9.5 | -7.8 | 5.1e-15 | 0.48 | 0.35 | 0.15 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MICAL3 | 0.10 | 0.09 | enet | 14 | 0.10 | 1.4e-09 | -10.7 | -9.9 | 2.8e-23 | 0.85 | 0.00 | 1.00 | FALSE |