Best TWAS P=1.63e-16 · Best GWAS P=2.69e-15 conditioned to 0.00319
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | ZDHHC8 | 0.27 | 0.14 | lasso | 10 | 0.07 | 8.1e-03 | 7.3 | 7.5 | 4.7e-14 | 0.84 | 0.02 | 0.79 | FALSE |
| 2 | GTEx | Brain Cortex | ZDHHC8 | 0.30 | 0.04 | lasso | 4 | 0.03 | 6.1e-02 | 6.1 | 8.2 | 1.6e-16 | 0.61 | 0.05 | 0.34 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | ARVCF | 0.25 | 0.10 | enet | 23 | 0.16 | 4.3e-12 | -4.7 | -5.3 | 1.2e-07 | -0.11 | 1.00 | 0.00 | TRUE |