[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr1:8,467,353-11,222,393

Best TWAS P=5.71e-09 · Best GWAS P=1.08e-16 conditioned to 5.15e-16

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous DFFA 0.11 0.08 enet 8 0.06 1.3e-05 -4.2 5.2 2.6e-07 0.03 0.40 0.51 FALSE
2 GTEx Cells Transformed fibroblasts PGD 0.47 0.56 enet 15 0.55 7.5e-49 -5.2 -5.1 2.8e-07 0.02 0.04 0.96 FALSE
3 GTEx Esophagus Mucosa GPR157 0.18 0.08 lasso 4 0.09 1.3e-06 5.5 5.7 1.6e-08 0.04 0.96 0.00 FALSE
4 GTEx Lung KIF1B 0.09 0.11 lasso 2 0.10 7.8e-08 -5.6 -5.5 3.2e-08 0.02 0.01 0.99 FALSE
5 GTEx Skin Sun Exposed Lower leg GPR157 0.18 0.09 lasso 2 0.09 7.6e-08 5.9 5.8 5.7e-09 0.02 0.99 0.00 TRUE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma PGD 0.04 0.02 blup 52 0.03 2.6e-03 -5.0 -5.8 5.8e-09 -0.01 0.01 0.90 TRUE
7 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PGD 0.09 0.02 blup 52 0.05 6.0e-03 -3.2 -5.1 2.7e-07 -0.01 0.01 0.49 FALSE