[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr1:8,467,353-11,222,393

Best TWAS P=5.71e-09 · Best GWAS P=1.08e-16 conditioned to 5.15e-16

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Skin Sun Exposed Lower leg	GPR157	0.18	0.09	lasso	2	0.09	7.6e-08	5.9	5.8	5.7e-09	0.02	0.99	0.00	TRUE
6	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PGD	0.04	0.02	blup	52	0.03	2.6e-03	-5.0	-5.8	5.8e-09	-0.01	0.01	0.90	TRUE
3	GTEx	Esophagus Mucosa	GPR157	0.18	0.08	lasso	4	0.09	1.3e-06	5.5	5.7	1.6e-08	0.04	0.96	0.00	FALSE
4	GTEx	Lung	KIF1B	0.09	0.11	lasso	2	0.10	7.8e-08	-5.6	-5.5	3.2e-08	0.02	0.01	0.99	FALSE
1	GTEx	Adipose Subcutaneous	DFFA	0.11	0.08	enet	8	0.06	1.3e-05	-4.2	5.2	2.6e-07	0.03	0.40	0.51	FALSE
7	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PGD	0.09	0.02	blup	52	0.05	6.0e-03	-3.2	-5.1	2.7e-07	-0.01	0.01	0.49	FALSE
2	GTEx	Cells Transformed fibroblasts	PGD	0.47	0.56	enet	15	0.55	7.5e-49	-5.2	-5.1	2.8e-07	0.02	0.04	0.96	FALSE