TWAS
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About
Usage
Models
Genes
Traits
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Traits
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Lung FEV1/FVC ratio
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chr2:55,401,562-56,843,605
Best TWAS P=3.95e-16 · Best GWAS P=3.58e-25 conditioned to 1.33e-10
55.4M
55.6M
55.8M
56M
56.2M
56.4M
56.6M
56.8M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
EFEMP1
0.02
0.01
blup
79
0.02
3.9e-05
9.6
-8.1
4.0e-16
-0.77
0.04
0.95
TRUE
1
GTEx
Brain Frontal Cortex BA9
EFEMP1
0.19
0.10
lasso
8
0.08
3.7e-03
8.7
7.0
2.7e-12
0.48
0.12
0.09
FALSE