Best TWAS P=3.95e-16 · Best GWAS P=3.58e-25 conditioned to 1.33e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | EFEMP1 | 0.19 | 0.10 | lasso | 8 | 0.08 | 3.7e-03 | 8.7 | 7.0 | 2.7e-12 | 0.48 | 0.12 | 0.09 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EFEMP1 | 0.02 | 0.01 | blup | 79 | 0.02 | 3.9e-05 | 9.6 | -8.1 | 4.0e-16 | -0.77 | 0.04 | 0.95 | TRUE |