[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr2:102,274,098-103,686,111

Best TWAS P=1.03e-19 · Best GWAS P=4.86e-21 conditioned to 9.11e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IL1RL1	0.18	0.06	blup	78	0.15	3.7e-09	-7.9	9.1	1.0e-19	0.75	0.01	0.99	TRUE
6	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL1RL1	0.08	0.08	enet	9	0.08	1.2e-09	6.8	8.4	5.4e-17	0.60	0.98	0.02	FALSE
8	The Cancer Genome Atlas	Lung Adenocarcinoma	IL1RL1	0.03	0.01	blup	78	0.02	4.7e-03	6.5	7.9	2.9e-15	0.61	0.05	0.65	FALSE
9	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	IL1RL1	0.19	0.05	blup	78	0.10	7.1e-05	-8.1	7.6	2.8e-14	0.64	0.15	0.60	FALSE
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	IL1RL1	0.02	0.01	blup	78	0.01	1.5e-03	-7.9	7.6	3.3e-14	0.70	0.03	0.84	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	IL1RL1	0.05	0.03	enet	6	0.03	9.7e-04	6.8	6.8	8.3e-12	0.42	0.72	0.03	FALSE
4	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IL1RL1	0.04	0.04	lasso	8	0.04	1.7e-05	7.1	6.6	5.0e-11	0.43	0.38	0.13	FALSE
5	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL18R1	0.06	0.01	blup	108	0.04	2.6e-05	-2.0	6.2	4.5e-10	0.52	0.04	0.65	FALSE
1	GTEx	Colon Transverse	IL18R1	0.14	0.00	enet	41	0.00	2.1e-01	-2.6	-5.7	1.0e-08	-0.17	0.07	0.04	FALSE
2	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IL1RL1	0.04	0.03	lasso	7	0.03	8.1e-04	3.8	5.3	1.0e-07	0.50	0.20	0.26	FALSE