[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr2:102,274,098-103,686,111

Best TWAS P=1.03e-19 · Best GWAS P=4.86e-21 conditioned to 9.11e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Colon Transverse IL18R1 0.14 0.00 enet 41 0.00 2.1e-01 -2.6 -5.7 1.0e-08 -0.17 0.07 0.04 FALSE
2 The Cancer Genome Atlas Bladder Urothelial Carcinoma IL1RL1 0.04 0.03 lasso 7 0.03 8.1e-04 3.8 5.3 1.0e-07 0.50 0.20 0.26 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma IL1RL1 0.02 0.01 blup 78 0.01 1.5e-03 -7.9 7.6 3.3e-14 0.70 0.03 0.84 FALSE
4 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma IL1RL1 0.04 0.04 lasso 8 0.04 1.7e-05 7.1 6.6 5.0e-11 0.43 0.38 0.13 FALSE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IL18R1 0.06 0.01 blup 108 0.04 2.6e-05 -2.0 6.2 4.5e-10 0.52 0.04 0.65 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IL1RL1 0.08 0.08 enet 9 0.08 1.2e-09 6.8 8.4 5.4e-17 0.60 0.98 0.02 FALSE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma IL1RL1 0.18 0.06 blup 78 0.15 3.7e-09 -7.9 9.1 1.0e-19 0.75 0.01 0.99 TRUE
8 The Cancer Genome Atlas Lung Adenocarcinoma IL1RL1 0.03 0.01 blup 78 0.02 4.7e-03 6.5 7.9 2.9e-15 0.61 0.05 0.65 FALSE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma IL1RL1 0.19 0.05 blup 78 0.10 7.1e-05 -8.1 7.6 2.8e-14 0.64 0.15 0.60 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma IL1RL1 0.05 0.03 enet 6 0.03 9.7e-04 6.8 6.8 8.3e-12 0.42 0.72 0.03 FALSE