Hub : Genes

IL18R1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3130	0.0430	0.0e+00	0.378	0.337	0.377	0.381	0.380	1.8e-48	3.2e-42	2.1e-48	5.4e-49	6.9e-49
2	GTEx	Brain Caudate basal ganglia	0.1690	0.0650	5.1e-03	0.230	NA	0.175	NA	0.204	3.0e-07	NA	9.7e-06	NA	1.6e-06
3	GTEx	Brain Cerebellar Hemisphere	0.2450	0.0860	2.1e-03	0.252	NA	0.098	NA	0.033	3.7e-07	NA	1.8e-03	NA	4.8e-02
4	GTEx	Brain Cerebellum	0.2490	0.0660	2.5e-05	0.303	NA	0.256	NA	0.256	1.2e-09	NA	3.4e-08	NA	3.6e-08
5	GTEx	Brain Cortex	0.2140	0.0760	2.6e-03	0.119	NA	0.103	NA	0.132	3.6e-04	NA	8.7e-04	NA	1.7e-04
6	GTEx	Brain Hippocampus	0.2514	0.0820	5.4e-04	0.058	NA	0.032	NA	0.069	1.7e-02	NA	6.2e-02	NA	1.0e-02
7	GTEx	Brain Putamen basal ganglia	0.2960	0.0940	1.9e-03	0.225	NA	0.243	NA	0.211	4.6e-06	NA	1.8e-06	NA	9.6e-06
8	GTEx	Colon Transverse	0.1380	0.0550	5.4e-03	-0.002	NA	0.003	NA	-0.004	4.4e-01	NA	2.1e-01	NA	5.6e-01
9	GTEx	Lung	0.0600	0.0282	8.8e-03	0.009	NA	0.005	NA	0.019	5.8e-02	NA	1.2e-01	NA	1.2e-02
10	GTEx	Skin Sun Exposed Lower leg	0.0470	0.0220	9.2e-03	0.023	NA	0.003	NA	0.020	5.1e-03	NA	1.8e-01	NA	7.4e-03
11	GTEx	Thyroid	0.0830	0.0310	1.2e-03	-0.001	NA	0.000	NA	-0.002	4.3e-01	NA	3.5e-01	NA	5.6e-01
12	GTEx	Uterus	0.2610	0.1130	7.6e-03	0.079	NA	0.004	NA	0.025	1.1e-02	NA	2.6e-01	NA	1.0e-01
13	GTEx	Whole Blood	0.0650	0.0280	6.2e-03	-0.001	NA	0.013	NA	-0.001	3.8e-01	NA	2.1e-02	NA	3.9e-01
14	NTR	Blood	0.0534	0.0183	3.5e-05	0.023	0.016	0.018	0.019	0.018	4.3e-08	5.9e-06	1.1e-06	5.1e-07	1.1e-06
15	ROSMAP	Brain Pre-frontal Cortex	0.4167	0.0463	0.0e+00	0.517	0.451	0.508	0.506	0.518	1.4e-77	2.2e-64	1.2e-75	2.5e-75	6.2e-78
16	YFS	Blood	0.1874	0.0328	0.0e+00	0.096	0.169	0.167	0.167	0.154	8.1e-30	7.9e-53	3.3e-52	3.0e-52	4.4e-48
17	TCGA	Breast Invasive Carcinoma	0.0541	0.0224	1.2e-07	0.015	0.033	0.029	NA	0.030	3.7e-04	1.8e-07	1.2e-06	NA	5.7e-07
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.0636	0.0302	4.0e-04	0.010	0.040	0.020	NA	0.015	2.4e-02	2.6e-05	2.2e-03	NA	7.5e-03
19	TCGA	Brain Lower Grade Glioma	0.2484	0.0591	0.0e+00	0.292	0.308	0.304	NA	0.307	2.2e-33	1.6e-35	4.9e-35	NA	2.4e-35

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Bipolar Disorder (2018)	0.6	0.9	4.9	0.4	0.3	0.1	0.2	0.3	1.2	-0.3	2.2	0.4	0.7	1.9	-0.4	1.8	1.0	0.3	0.6	0.8	0.1	0.3
Bipolar Disorder or Schizophrenia	0.3	0.8	3.9	-0.7	-0.4	-0.5	-0.9	-0.6	-0.9	-0.7	0.1	-0.8	-0.4	1.6	-1.0	0.3	0.9	-0.4	2.0	-0.3	0.9	-1.0
Depressed Affect (Nagel 2018)	1.1	2.4	10.9	0.3	1.1	1.7	1.2	0.7	-0.6	1.5	-1.3	0.1	-1.3	-3.3	-1.1	-2.8	0.9	1.0	1.3	-2.4	-2.1	0.6
Depression (Nagel 2018)	0.9	1.3	7.5	0.3	1.0	1.2	0.1	0.3	0.0	1.0	-0.8	0.4	-0.3	-1.9	-2.7	-1.6	-0.5	1.0	0.8	-2.0	-0.3	0.4
Intelligence (Savage-Jansen 2018)	2.1	6.4	14.1	-3.3	-2.6	-2.5	-3.1	-2.7	-2.6	-2.5	-2.3	-3.4	-3.4	0.3	-0.3	-0.2	2.3	-2.5	3.7	0.5	0.6	-3.4
Neuroticism (Nagel 2018)	1.2	2.8	12.0	-0.1	0.6	0.7	0.3	-0.0	-1.4	1.0	-2.6	-0.2	-1.9	-3.0	-2.0	-3.5	0.0	0.5	1.2	-3.1	-1.6	0.0
Schizophrenia (2018)	0.7	1.5	4.8	-1.2	-0.8	-0.7	-1.3	-1.1	-2.2	-0.6	-1.6	-1.4	-1.1	0.5	-1.0	-1.1	0.5	-0.7	2.0	-1.0	1.0	-1.4
Schizophrenia vs Biploar Disorder	0.8	1.1	3.7	0.9	1.2	0.8	0.9	1.0	1.2	1.2	-1.9	0.8	0.5	-0.9	-0.5	-0.8	-1.3	1.2	0.1	-1.8	-0.1	0.8
Worry (Nagel 2018)	0.3	0.6	3.9	0.3	0.5	0.1	0.3	0.3	0.3	0.3	-2.0	0.1	0.2	-0.0	-0.3	-1.8	-0.5	0.4	0.4	-1.6	0.9	-0.1
Alzheimer’s Disease (in mother)	1.9	2.3	9.1	-2.0	-1.9	-1.3	-1.3	-1.8	-1.5	-3.0	1.0	-1.8	-1.6	0.6	0.5	1.0	0.9	-1.8	1.2	1.0	-0.6	-1.7
Alzheimer’s Disease (in father)	1.0	1.1	3.3	-1.2	-0.9	-0.3	-0.7	-0.8	-1.6	-0.6	-0.6	-1.5	-1.6	-0.8	0.2	-0.0	1.8	-0.9	1.4	0.7	-1.1	-0.9
Alzheimer’s Disease (including proxy)	2.6	3.7	9.4	-2.6	-2.2	-1.4	-1.7	-2.1	-2.0	-3.1	0.2	-2.8	-1.8	0.4	0.9	0.9	2.5	-2.3	2.0	1.9	-0.6	-2.1
Crohns Disease (2017)	11.2	24.6	51.4	6.7	6.7	5.8	6.2	6.7	6.5	6.3	0.6	5.8	7.2	1.3	-0.2	0.1	-1.0	6.7	-3.2	-1.3	1.7	5.6
Irritable Bowel Disease (IBD)	10.0	23.7	44.9	6.2	6.7	6.3	6.2	6.6	5.7	6.4	0.2	5.5	6.5	-0.3	-0.6	-1.0	-1.3	6.7	-3.4	-2.3	0.7	6.0
Ulcerative Colitis (UC)	4.5	8.4	16.1	3.4	4.0	4.0	3.6	3.7	2.4	4.0	-0.2	3.1	3.1	-1.6	-1.4	-1.5	-0.8	4.0	-2.5	-2.3	-0.6	3.9
Major Depression (MDD)	0.6	0.7	4.2	-0.2	0.4	0.4	1.0	0.6	0.6	0.6	-2.1	0.0	-0.3	-1.4	1.4	-0.5	-0.8	0.3	-0.5	-0.8	-0.9	-0.1
Reaction Time	0.6	1.2	7.2	1.0	1.0	1.0	0.2	0.5	0.4	1.5	-0.2	1.1	0.3	-1.2	-2.7	-0.4	-0.9	1.0	-1.3	-0.7	-0.5	1.3
Verbal and Numeric Reasoning (VNR)	1.2	2.9	6.0	-1.9	-1.5	-1.8	-2.2	-1.7	-2.0	-1.9	-1.9	-1.9	-2.4	0.3	-0.5	-1.4	0.7	-1.5	2.5	-1.1	0.9	-2.2
Breast Cancer	0.2	0.5	3.1	-0.3	-0.1	-0.2	-0.3	-0.1	-0.2	-0.3	-1.5	-0.6	0.5	1.3	0.0	-0.2	0.3	-0.1	0.6	0.6	1.8	-1.0
Ovarian Cancer	0.3	0.3	1.6	-0.5	-0.3	0.1	-0.3	-0.3	0.3	-0.6	-0.8	-0.4	0.1	0.5	0.0	1.3	1.0	-0.2	0.8	1.0	0.2	-0.3
Prostate Cancer	1.2	1.7	5.9	1.5	1.7	1.2	1.4	1.6	1.5	2.4	-0.3	1.2	1.5	-0.2	-0.7	-1.1	-1.3	1.7	-0.1	-1.5	0.6	1.2
Age at First Birth	0.4	0.6	2.6	-0.3	-0.5	-0.2	0.0	-0.3	0.0	0.1	0.4	0.2	-0.4	-0.8	0.8	0.9	1.4	-0.5	-1.5	0.9	-1.6	0.4
Bipolar Disorder (2011)	0.5	0.5	2.0	-0.5	-0.6	-0.6	-0.4	-0.4	0.7	-0.7	1.0	-0.4	0.9	1.4	0.6	1.0	0.3	-0.5	-0.0	0.7	1.1	-0.4
Body Mass Index (BMI) (2010)	0.6	0.8	1.8	1.0	1.0	0.8	0.9	1.0	0.9	1.4	-0.3	1.2	0.1	-0.5	-0.3	-0.9	-0.4	1.0	-0.6	-1.0	-1.0	1.2
Coronary Artery Disease (CAD)	1.9	2.3	5.1	1.9	1.5	1.8	2.2	1.9	1.3	1.3	-0.8	1.9	1.2	-0.8	0.5	-1.4	1.2	1.7	-0.4	0.1	-2.3	2.0
Crohns Disease (2012)	10.2	16.5	37.2	5.2	5.1	4.5	4.8	5.2	5.6	5.1	1.0	4.7	6.1	1.3	-0.1	1.0	-1.1	5.2	-4.0	-0.6	1.5	4.7
Mean Putamen Volume	0.4	0.5	1.9	0.5	0.2	0.6	0.2	0.3	0.2	0.8	0.3	0.8	1.2	-0.6	0.2	1.2	1.4	0.2	-0.9	0.8	0.1	0.7
Fasting Glucose	1.2	1.5	5.5	-1.1	-0.8	-0.3	-1.5	-1.4	-1.0	-0.9	0.4	-1.4	-0.8	0.8	-2.1	-0.3	2.3	-0.9	1.6	1.0	-0.1	-1.2
HbA1C	0.4	0.5	2.8	0.2	0.2	-0.4	0.2	0.5	-0.8	0.0	0.1	0.3	-1.4	0.7	1.3	-0.3	0.4	0.1	0.9	0.2	-1.7	0.3
HDL Cholesterol	0.3	0.5	4.7	-0.0	-0.4	-0.9	-0.8	-0.5	-0.3	0.1	0.4	0.3	0.1	0.8	-0.4	0.6	-2.2	-0.4	-1.2	0.3	0.1	0.0
LDL Cholesterol	0.5	0.8	3.6	1.1	1.1	0.7	0.7	0.9	0.8	0.8	0.2	0.9	-0.1	0.0	-0.9	-1.9	-0.1	1.2	0.1	-1.6	-0.6	0.9
Lupus	1.8	2.8	6.6	1.9	2.0	2.6	2.1	1.9	1.4	2.0	-0.5	1.3	1.4	-0.6	-0.2	-2.5	-0.3	2.1	0.6	-2.3	-0.2	1.9
Neuroticism (2016)	1.5	2.1	10.6	0.3	0.7	0.8	0.7	0.4	-0.7	1.1	-0.5	0.6	-1.6	-3.3	-1.8	-2.4	-1.0	0.7	-0.9	-2.2	-2.4	0.8
Primary Biliary Cirrhosis	1.2	1.7	4.8	1.0	1.6	2.1	1.1	1.3	0.9	1.4	-2.2	0.9	0.6	-1.1	-1.2	-0.9	1.3	1.6	0.1	-1.1	-0.7	1.6
Rheumatoid Arthritis	0.7	1.0	6.4	-1.1	-1.0	-1.3	-0.6	-0.5	0.4	-1.2	0.2	-1.0	0.1	0.7	2.5	0.7	-1.1	-1.0	-0.8	0.8	0.7	-0.9
Schizophrenia (2014)	0.2	0.4	1.7	-0.2	0.0	-0.2	-0.3	-0.1	-0.6	0.3	-0.8	-0.3	0.2	1.3	-0.3	0.3	0.3	0.1	1.0	-1.1	1.1	-0.6
Triglycerides	0.3	0.5	2.4	0.2	0.4	0.5	0.3	0.5	1.1	-0.2	-1.4	-0.2	1.6	0.4	0.4	-0.4	0.3	0.5	-0.4	0.4	1.2	0.1
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.8	-0.0	-0.1	-0.3	-0.4	-0.2	0.8	0.2	-0.2	-0.1	1.2	0.4	-0.2	0.7	-0.1	-0.0	-1.3	0.4	1.2	0.1
Ulcerative Colitis	5.2	7.5	13.9	3.2	3.7	3.7	2.9	3.4	3.1	3.7	-0.2	3.0	3.7	-1.1	-1.3	-0.9	-0.8	3.7	-2.7	-1.5	0.0	3.6
Blood Eosinophil Count	18.4	141.9	756.2	-1.1	-9.7	-7.7	-1.5	-6.6	-1.7	-8.6	27.5	2.6	1.6	9.6	8.8	22.3	14.4	-9.6	-0.3	24.0	-10.0	3.0
Blood Platelet Count	0.4	4.3	24.2	1.0	1.4	2.3	2.9	1.7	0.1	1.4	0.5	1.8	-1.2	-4.9	0.6	-0.0	0.1	1.5	-0.0	-1.2	-4.8	2.1
Blood Red Count	0.2	1.6	7.8	0.5	0.6	0.7	0.8	0.9	1.9	0.3	-1.6	0.0	2.4	1.9	1.5	0.6	-1.0	0.6	-0.7	0.3	2.8	-0.0
Blood White Count	0.3	2.5	18.4	-0.0	-0.4	0.4	1.5	0.1	-1.0	0.1	1.4	0.6	-2.0	-3.7	1.5	0.8	0.9	-0.2	-0.2	-0.0	-4.3	1.0
Heel T-Score	0.1	1.0	3.0	-0.7	-0.8	-1.4	-1.3	-0.6	0.4	-0.5	-0.9	-0.5	0.4	0.8	1.2	-0.5	-1.6	-0.8	-1.7	-0.2	1.5	-0.8
BMI	0.6	3.7	11.6	2.4	2.3	2.2	2.1	2.4	1.5	3.4	-1.8	2.3	1.3	-0.1	0.5	-0.5	-1.2	2.2	-1.9	-1.7	-0.0	2.4
Height	0.9	17.9	106.1	-4.0	-3.5	-3.4	-3.6	-3.7	-5.1	-4.7	-1.4	-5.1	-5.2	3.0	-0.3	-2.2	2.7	-3.6	10.3	0.5	1.2	-5.3
Waist Hip Ratio (WHR)	0.1	0.6	4.7	0.9	0.6	0.6	0.4	0.2	0.3	0.5	0.8	0.8	0.5	-0.6	-2.2	0.2	-1.1	0.6	-0.4	-0.0	-0.1	0.6
Systolic Blood Pressure	0.6	3.1	11.1	1.6	1.7	1.2	0.6	1.0	0.7	1.4	-0.6	2.4	0.9	-1.7	-3.2	-1.6	-2.2	1.7	-1.8	-3.3	-0.2	1.8
Smoking Status	0.9	2.0	8.1	-0.8	-1.2	-1.4	-1.3	-1.5	-1.2	-0.9	1.2	-1.4	-0.1	1.9	-0.8	1.6	0.5	-1.2	2.8	1.7	1.9	-1.5
Allergy or Eczema	11.9	31.2	130.0	4.9	1.4	3.0	4.8	2.2	4.1	2.8	11.4	6.0	4.1	0.1	0.6	8.4	7.1	1.6	-2.6	8.6	-8.3	7.0
Cardiovascular Disease	0.6	1.9	7.9	-1.4	-0.9	-0.8	-1.2	-1.2	-2.2	-0.2	-1.0	-1.0	-2.4	-2.8	-1.3	-1.2	-0.4	-0.9	-0.1	-0.8	-1.8	-0.6
Hypothyroidism (self reported)	0.9	2.1	4.3	1.8	1.8	1.7	1.7	1.6	1.0	2.0	1.3	2.1	0.5	-0.8	-1.1	-0.6	-1.3	1.9	-0.6	-1.7	-1.1	1.7
Respiratory disease	10.6	23.6	141.6	-0.3	-3.4	-1.4	-0.1	-2.7	-1.6	-1.7	11.9	1.4	-0.4	-0.8	0.9	8.2	6.7	-3.3	-0.9	9.1	-8.1	2.2
Type 2 Diabetes (T2D) (2018)	0.5	0.9	2.6	-1.1	-1.1	-0.7	-1.6	-1.2	-0.8	-0.9	0.1	-1.0	0.5	0.9	-0.2	0.7	-0.5	-1.1	-0.5	1.4	1.6	-0.8
Lung FEV1/FVC ratio	2.6	13.0	38.8	3.2	3.9	2.5	2.1	3.8	4.5	3.5	-5.7	1.9	4.6	4.7	0.7	-2.1	-3.9	3.8	-0.5	-3.0	6.2	1.2
Lung FVC	0.4	1.9	8.3	0.6	0.6	0.1	0.2	0.2	-1.6	-0.2	-1.2	0.0	-2.1	-0.8	-2.1	-2.9	0.2	0.6	2.6	-2.1	-1.3	-0.3
Neuroticism	0.9	2.2	8.9	0.5	1.2	1.6	1.5	1.0	-0.2	1.2	-1.9	0.3	-0.8	-2.6	-0.7	-3.0	1.0	1.2	1.4	-2.1	-1.7	0.6
Chronotype (morning person)	1.8	4.1	9.1	1.9	2.2	2.6	2.5	2.3	1.4	2.6	-0.6	1.8	-0.0	-2.7	-0.1	-3.0	-1.0	2.3	-0.1	-2.7	-2.0	2.4
Hair Pigment	0.2	7.1	16.0	2.9	2.8	2.8	3.3	2.9	2.7	4.0	-0.6	3.2	1.8	-3.4	0.2	-0.4	-2.2	2.8	-3.6	-1.9	-1.8	3.1
Tanning	0.7	8.3	21.4	-3.1	-3.5	-3.6	-3.6	-3.6	-4.3	-3.8	1.0	-2.7	-4.6	-0.4	-0.4	-0.6	0.6	-3.5	3.1	1.2	-1.4	-2.9
Hand grip strength (left)	0.4	1.0	2.3	-1.1	-1.2	-0.9	-0.7	-1.1	-0.7	-1.5	1.4	-1.3	-0.4	1.0	0.7	0.4	0.2	-1.2	1.3	0.5	0.7	-1.5
Number of treatments/medications taken	0.6	1.2	7.4	-0.7	-0.7	0.3	-0.3	-0.7	-0.5	0.3	0.7	0.1	-1.0	-2.7	-0.3	0.7	1.0	-0.6	-1.4	0.5	-2.7	0.4
Average weekly spirits intake	0.3	0.3	2.1	-0.5	-0.2	-0.2	-0.5	-0.4	0.5	0.1	0.0	-0.4	0.0	0.1	-1.3	0.8	-0.4	-0.1	1.4	0.3	0.1	-0.4
Sensitivity / hurt feelings	0.7	1.1	4.8	-1.3	-0.8	-0.7	-0.9	-0.9	-1.1	-0.4	-2.2	-0.8	-1.3	-1.9	0.1	-1.3	-0.2	-0.9	-0.2	-1.1	-0.4	-0.9
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.4	0.5	0.7	0.8	0.1	0.3	1.1	0.5	-1.0	0.6	0.8	-0.6	-1.6	-1.2	-0.4	0.7	-0.4	-0.3	0.5	0.4
Hearing difficulty/problems: Yes	0.7	1.1	6.0	-0.6	-0.4	-0.7	-1.3	-0.9	-0.2	-0.1	-1.1	-0.2	-1.7	-1.3	-2.4	-1.4	-1.0	-0.4	0.3	-0.8	-1.2	-0.6
Relative age of first facial hair	0.2	0.5	3.4	0.2	0.3	0.0	0.2	0.5	0.4	-0.1	0.2	0.4	0.9	0.4	0.5	0.9	-1.8	0.3	-1.2	-0.3	1.2	-0.0
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	2.4	1.1	1.2	1.3	1.5	1.5	1.2	1.1	0.7	1.2	0.6	-1.4	1.0	-0.2	-0.1	1.3	-1.2	0.0	-1.2	1.1
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.2	0.2	0.5	-0.2	-0.5	0.2	0.4	0.2	-0.7	0.1	0.2	0.4	-1.1	-0.1	-0.8	0.4	-0.1	-0.7	1.0	-0.3
Ever had hysterectomy (womb removed)	1.1	1.3	4.5	0.5	0.7	0.4	0.7	0.6	-0.3	1.4	-0.0	0.9	-1.2	-1.6	-0.9	-2.0	-1.5	0.7	-0.6	-1.7	-2.1	0.8
Systolic blood pressure, automated reading	0.3	0.8	3.8	0.9	0.9	0.2	0.4	0.6	0.8	1.1	-0.3	1.2	0.6	0.5	-0.7	-1.2	-1.4	0.8	-0.6	-2.0	0.7	0.7
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.8	-0.9	-0.6	-0.6	-0.3	-0.5	-1.2	0.2	-1.1	-0.4	-0.9	-1.3	0.5	-1.3	-0.7	-0.6	-0.4	-0.8	-0.1	-0.5
Angina	1.0	1.3	6.2	0.6	0.8	0.9	0.2	0.3	0.1	1.3	0.3	0.7	-0.9	-2.3	-2.5	-1.7	0.0	0.9	-0.2	-1.0	-1.8	1.0
Medication for hormone replacement therapy	0.2	0.2	1.3	0.1	0.2	-0.1	-0.3	0.0	-0.3	0.5	-0.6	0.0	-0.0	-0.3	-1.1	-0.6	-0.6	0.2	0.4	-0.3	0.2	-0.4
Vitamin and mineral supplements	0.9	1.3	4.8	-0.4	-0.6	-0.4	-0.7	-0.7	0.8	-0.9	0.7	-0.8	1.3	2.1	0.0	2.2	1.2	-0.6	0.8	1.5	2.0	-0.4
Supplements: Zinc	0.4	0.4	2.2	-0.5	-0.6	-0.5	-0.1	-0.4	0.1	-0.4	0.0	-0.2	1.1	-0.2	1.0	0.2	-0.3	-0.6	-1.5	1.0	0.9	-0.3
Medication: Co-codamol	2.0	2.3	4.2	-2.1	-1.7	-1.8	-2.0	-2.0	-1.5	-1.5	-0.6	-2.0	-2.0	-0.1	-0.8	-0.0	1.3	-1.8	1.6	0.7	0.2	-2.0
Medication: Metformin	0.1	0.2	0.8	-0.7	-0.6	0.3	0.0	-0.5	-0.2	-0.3	0.4	-0.5	0.5	-0.6	0.3	0.9	0.0	-0.5	-0.3	0.6	0.2	0.0
Diabetes (father)	1.5	1.8	5.1	1.5	1.5	0.5	1.2	1.4	0.1	1.8	-0.6	1.9	-0.0	-0.9	-0.8	-1.2	-2.0	1.5	-1.4	-2.3	-0.2	1.7
Diabetes (mother)	2.4	3.0	5.4	2.2	2.1	2.3	2.1	2.2	1.9	1.8	-1.6	2.2	1.5	-0.3	-0.3	-1.7	-0.5	2.2	-1.4	-1.3	-0.7	2.3
Severe depression (siblings)	2.6	2.9	5.1	1.8	2.2	2.2	2.0	2.1	0.6	1.9	0.1	1.7	0.7	-2.3	-0.5	-1.6	-1.6	2.2	-1.1	-2.3	-1.1	1.8
Pack years adult smoking proportion	0.5	0.7	1.9	0.8	0.9	0.3	0.0	0.6	1.4	1.0	-1.0	1.1	0.9	-0.2	-1.0	-0.3	-0.6	0.9	-0.9	-0.9	1.2	0.7
Impedance of leg (right)	0.1	0.7	5.1	0.4	0.2	0.5	0.1	-0.0	0.6	-0.9	2.2	0.4	0.6	-1.0	-1.6	-0.1	0.2	0.2	-0.3	0.4	-1.3	0.8
Leg fat-free mass (left)	0.2	1.0	4.6	0.2	0.0	-0.3	0.2	0.2	-1.6	1.0	-2.0	-0.2	-1.5	1.2	1.1	-1.0	0.3	-0.0	2.1	-0.5	0.2	-0.4
Trunk fat percentage	0.3	1.2	2.7	1.4	1.1	1.0	1.2	1.2	1.4	1.6	-0.9	1.2	1.6	0.9	0.7	-0.4	-0.3	1.1	-0.9	0.0	0.9	1.4
Hand grip strength (right)	0.7	1.9	4.8	-1.3	-1.5	-1.6	-1.2	-1.6	-1.8	-2.0	1.4	-1.6	-1.8	0.3	-0.4	-0.5	-0.4	-1.5	2.2	-0.2	-0.2	-1.7
Townsend deprivation index at recruitment	1.7	2.4	8.0	1.2	0.7	0.6	1.3	1.1	1.5	0.8	2.0	1.3	2.4	0.8	1.1	2.8	1.5	0.7	-2.0	2.8	0.1	1.4
Current tobacco smoking	0.4	0.7	2.5	0.0	-0.3	-0.5	-0.2	-0.7	-0.4	-0.2	1.0	-0.5	0.2	0.5	-1.5	1.6	1.1	-0.4	1.4	1.4	0.8	-0.6
Average weekly fortified wine intake	2.3	2.7	9.7	1.3	1.7	1.5	1.4	1.6	1.5	1.8	0.1	1.5	0.5	-1.5	-0.3	-2.6	-3.1	1.7	-1.0	-2.4	-0.9	1.2
Maternal smoking around birth	0.5	0.7	7.0	-0.6	-0.5	-0.2	-0.4	-0.5	-0.9	0.1	-1.1	-0.7	-0.3	-0.5	0.1	0.7	2.6	-0.5	-0.4	1.2	-0.6	-0.1
Fed-up feelings	0.8	1.5	7.3	-0.6	-0.1	0.7	0.3	-0.1	-1.1	-0.1	-0.9	-0.7	-1.5	-2.7	-0.3	-2.2	2.1	-0.0	1.3	-0.7	-1.8	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.9	4.0	1.4	1.7	2.0	1.4	1.3	0.7	1.9	0.3	1.6	0.2	-1.7	-1.7	-0.8	1.0	1.7	-0.1	-1.1	-1.4	1.6
Relative age voice broke	0.5	0.8	3.0	0.4	1.1	1.5	0.9	1.2	0.4	0.5	-1.7	0.3	0.3	-1.4	0.0	-0.8	-0.6	1.2	-0.8	-1.1	0.0	0.5
Taking other prescription medications	1.9	3.0	22.3	-0.3	-0.4	0.8	0.6	-0.5	-0.9	0.4	2.4	0.8	-1.4	-4.1	-0.5	1.0	1.5	-0.4	-1.0	0.7	-4.7	1.3
Age when periods started (menarche)	0.6	1.4	6.7	0.7	1.0	1.6	1.5	1.0	1.1	0.8	-2.6	0.2	0.2	-1.2	-0.3	-0.6	1.5	1.1	1.8	-0.5	-0.8	0.5
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	7.4	-1.3	-1.0	-1.0	-1.2	-1.3	-2.4	-0.5	-0.2	-1.0	-2.7	-0.7	-1.2	-1.2	0.3	-1.0	0.7	-1.3	-1.2	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.9	-0.2	-0.1	-0.4	-0.3	-0.0	-0.2	0.3	-0.0	0.2	0.0	-0.2	0.6	-0.7	-0.9	-0.2	-0.9	-0.6	0.1	0.1
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	2.5	0.6	0.3	0.6	0.7	0.5	1.4	-0.2	1.0	0.4	1.6	0.6	0.7	1.2	-1.0	0.4	-0.5	0.9	0.5	0.5
Qualifications: CSEs or equivalent	1.9	2.5	9.5	-0.3	-1.4	-1.9	-1.4	-1.0	-0.5	-1.1	2.5	-0.4	0.7	2.8	1.3	2.6	0.8	-1.4	-1.0	3.1	1.3	-0.3
Serious illness, injury or assault to yourself	2.2	2.7	5.6	1.7	2.0	1.4	1.7	2.1	1.7	2.1	0.2	2.4	1.3	-1.3	0.2	-0.3	-2.2	2.0	-2.2	-1.5	-0.0	1.9
High blood pressure	0.5	1.3	3.1	-1.4	-0.9	-1.1	-1.5	-1.2	-1.2	-0.2	-1.6	-1.1	-1.4	-1.8	-0.8	-1.5	-0.6	-1.0	-0.9	-0.8	-0.3	-0.9
Hayfever, allergic rhinitis or eczema	8.9	19.2	94.9	3.0	0.1	1.7	3.0	0.8	2.1	1.1	9.7	4.0	2.2	-0.3	0.4	6.8	6.3	0.2	-1.6	7.3	-7.5	4.9
Multivitamins +/- minerals	0.6	0.8	2.9	-0.6	-0.6	-0.4	-0.3	-0.5	-1.6	-0.1	-0.1	-0.2	-1.5	-1.3	-0.1	-1.7	-0.6	-0.5	0.6	-0.3	-1.7	-0.2
Stomach or abdominal pain in last month	0.3	0.4	1.8	0.2	0.2	-0.0	0.4	0.2	0.1	-0.2	-0.3	0.7	-0.3	-1.3	0.0	0.8	-0.9	0.1	-0.4	-0.4	-1.3	0.9
Supplements: Glucosamine	0.6	0.8	2.0	-1.1	-1.0	-1.0	-1.1	-0.7	-1.4	-0.8	-0.4	-1.2	-1.4	-0.0	1.0	-0.5	0.1	-1.0	-0.3	0.3	0.0	-1.3
Diverticular disease/diverticulitis (self-reported)	1.0	1.1	6.4	0.1	0.0	0.1	0.5	0.3	1.5	0.3	0.0	-0.0	1.8	1.2	1.4	2.5	0.3	-0.1	-0.5	2.2	1.0	-0.0
Medication: Atenolol	1.6	2.0	11.6	-1.1	-0.6	-0.8	-1.7	-1.1	-0.6	0.2	-3.4	-1.6	-0.7	0.5	-2.0	-1.1	-0.5	-0.5	0.6	-0.8	2.4	-1.8
Medication: Levothyroxine sodium	0.3	0.5	1.6	-0.5	-0.5	-1.2	-0.8	-0.8	-0.9	-0.1	0.9	-0.4	-0.9	0.7	-1.3	-0.0	-0.1	-0.5	0.7	0.4	0.0	-0.9
Sitting height	0.5	3.8	33.4	-1.0	-1.0	-1.1	-0.7	-0.9	-2.5	-0.9	-1.6	-1.8	-2.7	2.0	0.3	-1.0	1.8	-1.0	5.8	0.8	-0.4	-1.7
Chronic bronchitis/emphysema (father)	0.3	0.3	1.3	0.0	0.1	-1.0	-0.3	0.0	0.2	0.3	-1.1	0.2	-0.1	1.0	-0.6	0.6	-1.0	0.1	0.4	0.3	0.8	-0.4
High blood pressure (mother)	0.9	1.3	10.0	0.3	0.2	-0.1	0.6	0.8	1.2	0.1	-1.7	0.8	0.8	-0.2	2.5	-0.6	-0.9	0.2	-3.2	-0.2	0.6	0.7
Body mass index (BMI)	0.3	1.3	4.9	1.5	1.1	0.6	1.0	1.2	0.5	2.2	-1.1	1.6	0.4	0.4	0.6	-0.5	-1.0	1.1	-1.7	-0.8	-0.1	1.5
Impedance of leg (left)	0.1	0.7	5.0	0.4	0.3	0.6	0.3	0.1	0.8	-0.9	2.2	0.5	0.8	-0.8	-1.5	0.3	0.2	0.4	-0.2	0.5	-1.2	0.9
Leg predicted mass (left)	0.2	1.1	5.4	0.2	-0.0	-0.4	0.1	0.2	-1.6	0.9	-2.0	-0.2	-1.5	1.4	1.1	-0.9	0.3	-0.1	2.3	-0.4	0.3	-0.5
Trunk fat mass	0.1	0.5	1.8	0.9	0.5	0.3	0.7	0.7	0.3	1.2	-1.0	0.7	0.6	1.4	0.9	-0.5	-0.4	0.5	0.1	0.0	0.8	0.7
Waist circumference	0.1	0.4	1.7	0.9	0.5	-0.0	0.3	0.5	-0.2	1.3	-0.7	0.9	-0.4	0.6	0.0	-0.4	-1.3	0.4	-0.6	-0.6	0.0	0.7
Number of incorrect matches in round	0.8	1.4	6.6	-0.7	-1.1	-1.1	-1.3	-1.2	-0.6	-1.1	2.6	-0.5	0.8	0.5	-0.5	1.6	0.3	-1.0	-1.6	1.1	1.6	-0.8
Past tobacco smoking	0.7	1.2	3.7	0.7	1.0	1.4	1.3	1.1	1.4	1.1	-0.7	1.0	0.6	-1.7	0.1	-0.8	0.2	1.1	-1.9	-0.7	-1.0	1.4
Alcohol usually taken with meals	1.9	3.1	8.1	-2.1	-2.4	-2.3	-2.6	-2.1	-1.5	-2.8	0.6	-1.9	-0.5	1.2	0.9	-0.1	-1.2	-2.3	0.2	0.8	1.9	-2.4
Nervous feelings	0.4	0.7	4.1	-0.6	-0.4	-0.7	-0.9	-0.6	-1.0	-0.2	-2.0	-0.7	-0.3	0.8	-1.1	-0.1	0.4	-0.5	1.3	-0.4	1.1	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	4.1	0.4	0.6	0.8	0.6	0.4	-0.2	0.7	-1.4	0.7	-0.6	-2.0	-1.2	-1.1	0.2	0.6	-0.6	-0.8	-1.4	0.4
Hearing difficulty/problems with background noise	0.4	0.6	2.8	-0.6	-0.2	-0.7	-0.9	-0.5	-0.2	-0.6	-1.5	-0.2	-1.7	-0.2	-0.8	-0.6	-0.8	-0.3	1.0	-0.7	-0.7	-0.3
Hair/balding pattern: Pattern 2	0.5	0.6	2.2	-0.6	-0.8	-0.7	-0.8	-0.6	-0.0	-0.5	-0.6	-0.8	0.2	1.2	1.5	0.5	0.1	-0.8	0.1	0.9	1.4	-0.8
Had menopause	0.6	0.8	3.5	0.6	1.1	0.6	0.8	1.2	1.5	0.6	-1.9	0.5	0.8	0.0	1.0	-0.2	-1.1	0.9	-0.4	-0.6	0.5	0.2
Had other major operations	1.3	1.6	4.3	1.7	1.3	1.1	1.7	1.6	2.1	0.9	1.3	2.0	0.8	0.0	1.3	0.7	-1.0	1.3	-0.4	-0.1	-1.0	1.4
Forced vital capacity (FVC)	0.7	2.6	21.7	-0.1	-0.3	-0.7	-0.4	-0.6	-2.6	-1.4	-0.2	-0.7	-2.5	0.6	-1.6	-1.8	1.1	-0.4	4.7	-1.1	-1.0	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.5	0.1	0.3	0.5	0.1	0.4	-0.1	0.6	-0.2	0.3	0.1	-1.6	0.4	-1.3	-1.2	0.3	-1.0	-1.3	-0.4	0.6
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	4.3	-0.4	-1.0	-0.7	-0.6	-0.5	-0.6	-1.1	2.1	-0.4	-0.0	0.4	2.0	1.4	0.9	-1.1	-0.7	1.8	-0.0	-0.4
Qualifications: None of the above	0.3	0.7	2.0	0.9	1.0	0.8	0.8	0.7	1.3	0.4	-0.1	0.6	1.4	0.4	-1.1	0.5	0.1	1.0	0.8	0.1	0.8	0.7
Financial difficulties in last 2 years	0.8	1.0	2.3	0.9	0.8	1.2	1.1	0.7	0.7	1.3	-0.8	1.0	0.6	-0.7	-0.4	1.0	1.5	0.8	-0.9	1.2	-1.4	1.3
Mouth/teeth dental problems	0.8	1.3	2.6	-1.4	-1.4	-1.4	-1.3	-1.1	-0.7	-1.1	0.1	-1.5	-0.7	1.0	1.1	0.7	1.6	-1.3	0.6	0.8	0.7	-1.5
Heart attack	0.7	0.8	7.7	0.2	0.1	0.4	-0.5	-0.4	-0.9	-0.1	0.1	0.3	-1.0	-1.1	-2.8	-1.0	-1.0	0.2	0.2	-1.3	-0.8	0.1
Allergy	10.6	24.4	141.6	-1.9	1.6	-0.4	-1.8	0.7	-0.6	0.2	-11.9	-3.4	-1.2	0.0	-1.0	-8.2	-6.9	1.5	1.6	-9.2	8.8	-4.3
Pain all over the body in last month	0.2	0.2	1.1	0.3	0.3	0.2	0.2	0.3	0.5	-0.2	-0.6	0.6	0.3	-0.2	-0.0	-0.3	-0.1	0.3	-1.0	0.2	-0.6	0.6
Diabetes (self-reported)	0.3	0.4	1.9	-0.6	-0.4	0.3	-0.5	-0.5	-1.3	-0.0	-1.1	-0.1	-0.6	-1.4	-0.6	-0.8	0.1	-0.3	-0.2	-0.3	-0.4	-0.1
Hayfever/allergic rhinitis (self-reported)	6.7	8.8	42.9	-1.0	-2.9	-2.3	-1.3	-2.2	-0.1	-2.3	5.8	-0.3	0.2	2.0	2.5	5.1	3.7	-3.0	-0.4	6.6	-2.4	0.0
Medication: Ramipril	0.4	0.5	1.8	-0.7	-0.5	-0.3	-0.6	-0.5	-0.5	-0.7	-1.4	-0.6	0.4	-0.3	0.2	-0.6	-1.0	-0.4	-1.3	-0.3	0.9	-0.4
Medication: Simvastatin	0.7	1.1	5.0	0.6	1.1	1.6	1.0	0.9	0.8	0.9	-0.9	0.7	0.1	-1.1	-0.9	-1.2	-0.5	1.2	-1.1	-2.2	-0.5	0.7
Fluid intelligence score	2.0	4.2	8.9	-2.6	-2.1	-2.3	-3.0	-2.4	-2.8	-1.9	-1.5	-2.7	-2.3	0.4	-1.1	0.0	1.6	-2.1	2.1	0.3	1.3	-2.7
Illnesses of siblings	0.5	0.7	4.3	0.3	-0.3	-0.2	0.2	-0.0	0.2	0.1	1.8	0.1	0.3	0.7	0.7	2.1	1.5	-0.3	-0.1	1.4	0.3	0.1
Neuroticism score	0.7	1.4	7.8	-0.2	0.3	0.8	0.6	0.2	-0.8	0.5	-2.4	-0.2	-1.0	-2.2	-0.4	-2.8	0.7	0.3	0.6	-1.8	-0.9	-0.1
Weight	0.1	0.5	2.0	0.3	0.0	-0.5	-0.0	0.0	-1.2	0.8	-1.2	0.2	-1.2	1.3	0.6	-0.8	-0.4	-0.1	1.4	-0.3	0.1	0.0
Impedance of arm (right)	0.2	1.0	6.2	-0.2	0.1	0.7	0.3	0.2	1.9	-1.3	0.7	-0.4	2.5	0.6	0.3	0.8	0.7	0.2	0.3	1.5	1.4	0.1
Arm fat percentage (right)	0.4	1.7	3.9	1.7	1.3	1.1	1.3	1.4	1.4	2.0	-0.5	1.7	1.7	1.1	0.6	-0.0	-0.8	1.3	-1.6	-0.3	0.6	1.9
Trunk fat-free mass	0.5	2.7	13.1	-0.7	-1.1	-1.7	-1.2	-1.1	-3.2	-0.3	-0.7	-1.0	-3.4	1.4	0.3	-0.8	0.2	-1.2	3.6	-0.4	-0.7	-1.4
Hip circumference	0.1	0.4	2.7	0.2	0.0	-0.4	0.2	0.3	-0.6	0.3	-0.6	0.2	-0.9	1.2	1.6	-0.3	-0.9	-0.0	0.5	-0.5	0.1	0.1
Time employed in main current job	1.0	1.1	2.8	1.4	1.1	0.4	0.7	0.8	1.7	1.1	1.0	1.4	1.3	0.5	-0.9	0.9	-1.5	1.0	-1.3	0.4	0.2	1.0
Alcohol intake versus 10 years previously	0.5	0.7	1.7	-0.8	-0.6	-0.8	-1.0	-0.8	-1.2	-0.2	-0.3	-1.1	-1.1	-1.1	-1.0	-0.2	0.8	-0.5	0.9	-0.3	0.4	-1.3
Father’s age at death	0.5	0.7	4.5	-0.5	-0.1	-0.1	-0.0	-0.1	1.0	-0.1	-1.5	-0.2	0.0	-0.0	0.6	0.4	-2.1	-0.1	-1.1	-1.1	1.2	-0.8
Worrier / anxious feelings	0.2	0.4	2.3	-0.7	-0.5	-0.5	-0.4	-0.5	-0.6	-0.9	-1.5	-0.7	-0.3	0.4	0.2	-0.5	0.2	-0.6	0.8	-0.3	0.7	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.4	4.8	1.1	1.2	1.2	1.2	1.1	0.1	1.5	-1.6	1.2	-0.4	-2.2	-0.9	-0.8	-0.2	1.1	-0.8	-0.4	-1.8	1.1
Falls in the last year	0.9	1.2	2.8	1.3	1.3	1.5	0.7	1.0	0.7	1.3	0.0	1.4	0.4	-1.6	-1.7	-0.1	-0.0	1.4	-0.9	-1.3	-1.1	1.1
Hair/balding pattern: Pattern 3	0.8	1.1	3.5	-0.8	-1.0	-0.8	-0.8	-1.1	-0.6	-1.1	1.5	-1.0	0.6	1.5	-0.2	0.6	1.9	-1.0	0.0	1.6	1.1	-1.0
Number of live births	0.2	0.3	2.5	-0.2	0.1	-0.6	-0.5	-0.2	-0.0	-0.2	0.1	-0.4	-0.7	0.8	-0.8	-0.3	-0.6	-0.1	1.6	-0.1	-0.1	-0.3
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	12.3	1.4	1.3	0.4	0.8	1.1	-1.1	0.4	-2.2	0.6	-0.9	1.1	-1.1	-2.5	-0.3	1.3	3.5	-2.1	0.1	0.5
Pulse rate	0.3	0.5	6.0	0.0	-0.1	-0.4	0.5	0.5	0.4	0.5	-0.6	0.2	-0.1	0.5	2.5	1.3	0.4	-0.1	-0.2	0.8	-0.4	0.3
Happiness	0.2	0.2	1.9	-0.2	-0.4	-0.6	-0.4	-0.2	-0.3	0.2	0.3	-0.2	-0.5	0.3	0.9	-0.3	-0.3	-0.4	-1.4	0.1	-0.2	-0.4
Noisy workplace	1.3	1.7	4.0	1.5	1.2	0.9	1.7	1.3	1.6	1.6	1.0	2.0	0.9	-0.8	0.4	0.1	0.4	1.2	-1.9	0.1	-1.3	1.8
Qualifications: A levels/AS levels or equivalent	1.0	2.2	5.4	-2.1	-1.7	-0.9	-1.7	-1.5	-1.8	-1.5	0.2	-2.3	-1.1	0.5	0.9	1.1	1.6	-1.6	1.4	1.7	0.6	-2.1
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.2	0.2	0.3	-0.3	0.2	0.2	-0.0	0.9	-1.1	0.2	-1.0	-0.3	-0.6	0.3	0.0	0.3	0.1	-0.5	-0.6	-0.1
Mouth/teeth dental problems: Dentures	0.6	0.9	2.4	-1.2	-1.3	-1.5	-1.2	-1.3	-0.3	-1.4	0.3	-1.0	-0.9	0.4	0.2	0.4	-0.0	-1.3	0.6	1.3	-0.2	-1.0
Asthma	9.6	19.0	136.9	0.4	-2.5	-0.7	0.3	-1.8	-0.0	-1.5	11.7	2.0	0.7	-0.2	1.2	7.0	5.0	-2.5	-1.6	8.1	-7.0	2.8
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	3.0	-0.1	0.1	-0.3	0.1	0.4	-1.5	0.1	-1.3	0.1	-1.5	-1.7	0.4	-0.6	-1.5	0.1	-0.3	-0.7	-1.1	-0.2
Medication: Cholesterol lowering	0.5	0.7	3.2	-0.1	0.1	0.5	-0.3	-0.4	-0.8	0.4	-0.2	0.2	-1.0	-1.8	-1.8	-1.2	-0.4	0.1	-0.2	-1.6	-1.0	0.2
Depression (self-reported)	0.1	0.1	0.5	-0.2	-0.1	-0.0	-0.1	0.0	0.1	0.3	0.0	-0.2	-0.3	-0.4	0.7	-0.5	-0.6	-0.1	0.2	-0.5	0.1	-0.3
Medication: Lansoprazole	0.5	0.6	2.4	-0.1	-0.1	-0.4	-0.0	0.0	0.4	0.3	0.4	-0.1	1.3	0.7	0.8	1.1	-0.7	-0.2	-1.1	1.5	1.5	0.1
Prospective memory result	1.1	1.4	4.0	1.2	1.3	1.3	1.4	1.5	2.0	0.8	0.6	1.3	1.8	0.2	1.1	1.6	0.9	1.3	-0.0	0.2	0.3	1.4
Lung cancer (father)	0.7	0.8	2.3	-0.7	-1.0	-1.2	-0.8	-0.7	-1.0	-1.4	-0.2	-0.2	-1.5	-0.4	0.8	-0.6	-1.0	-1.0	-0.9	-0.1	-1.0	-0.6
Illnesses of mother	1.0	1.2	6.5	0.3	0.1	-0.3	-0.1	-0.3	-1.2	0.1	2.6	0.0	-0.8	0.7	-2.3	1.4	0.4	0.1	2.4	0.3	-0.7	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	9.9	0.8	0.9	-0.1	0.4	0.8	-0.6	0.2	-2.4	-0.1	-0.7	1.4	-0.5	-1.9	0.0	0.8	3.1	-0.9	0.3	-0.3
Pulse wave Arterial Stiffness index	0.2	0.2	1.3	0.2	-0.2	-0.4	-0.1	-0.2	-0.3	0.1	1.2	0.0	0.3	0.8	-0.5	1.0	-0.5	-0.2	0.3	-0.3	0.7	-0.3
Impedance of arm (left)	0.2	0.9	4.9	-0.3	0.1	0.5	0.3	0.1	1.5	-1.3	0.8	-0.6	2.2	0.4	0.1	0.5	1.0	0.1	0.8	1.6	1.4	-0.1
Arm fat mass (right)	0.3	1.0	3.6	1.5	1.1	0.8	1.0	1.2	0.5	1.9	-1.0	1.4	0.6	1.0	0.6	-0.5	-0.8	1.0	-0.6	-0.5	0.1	1.5
Trunk predicted mass	0.5	2.9	13.8	-0.8	-1.2	-1.8	-1.3	-1.2	-3.3	-0.4	-0.7	-1.1	-3.5	1.5	0.2	-0.8	0.2	-1.3	3.7	-0.3	-0.7	-1.4
Standing height	0.7	6.5	44.0	-2.0	-2.1	-2.3	-2.0	-2.1	-3.4	-2.6	-0.2	-2.7	-3.2	2.3	-0.1	-1.0	1.1	-2.2	6.6	0.7	0.5	-2.9
Length of working week for main job	0.2	0.2	0.8	0.3	-0.2	-0.4	0.1	-0.1	-0.9	0.4	0.6	0.5	-0.4	-0.4	0.2	0.4	0.9	-0.2	0.5	0.4	-0.9	0.5
Exposure to tobacco smoke at home	0.3	0.4	1.5	-0.4	-0.6	-0.9	-0.7	-0.7	-0.2	-0.7	0.2	-0.0	-1.2	0.3	-0.2	-0.7	-0.6	-0.6	0.6	-0.5	-0.2	-0.4
Breastfed as a baby	0.4	0.6	1.5	0.9	1.2	0.9	0.4	1.0	0.7	0.8	-0.7	0.6	0.5	-0.3	-1.0	0.4	1.0	1.1	0.5	-0.2	0.2	0.2
Tense / ‘highly strung’	0.4	0.6	3.7	0.6	0.3	-0.2	0.1	0.2	0.3	0.7	0.3	1.0	0.3	-0.2	0.1	-1.5	-1.9	0.3	-1.1	-1.1	0.4	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	4.3	-1.9	-1.7	-1.5	-1.6	-1.7	-1.2	-1.6	-2.1	-2.0	-0.8	-0.3	0.7	-1.0	0.0	-1.8	0.5	1.0	1.1	-1.9
Hair/balding pattern: Pattern 4	0.3	0.8	3.8	0.4	0.5	0.1	0.2	0.4	0.2	0.7	-1.3	0.4	0.6	-1.8	-0.6	-0.7	-2.0	0.6	-1.4	-0.8	0.5	0.3
Birth weight of first child	1.4	2.5	8.3	-1.5	-1.6	-1.2	-1.7	-1.8	-1.4	-2.0	0.2	-2.0	-1.3	1.9	-0.5	-0.0	1.9	-1.6	2.9	1.1	0.6	-1.8
Peak expiratory flow (PEF)	0.3	0.7	1.6	1.2	1.0	0.8	1.3	1.2	-0.0	0.8	0.2	0.9	-0.1	-0.3	0.1	-0.8	0.3	1.1	1.0	-1.1	-1.0	1.0
Pulse wave reflection index	1.4	1.7	8.0	1.8	1.4	1.5	1.5	1.2	0.9	1.1	2.8	1.3	2.1	0.9	-1.0	0.4	-0.5	1.4	0.1	0.0	0.8	1.1
Ever highly irritable/argumentative for 2 days	2.1	2.5	4.5	1.9	1.9	1.9	1.9	1.9	1.7	1.4	0.6	1.9	1.0	-2.0	0.1	-1.1	-1.0	1.9	-1.6	-0.7	-1.5	2.1
Loud music exposure frequency	0.6	0.6	3.7	0.1	-0.4	-0.5	0.1	-0.3	-0.1	-0.5	1.3	0.5	0.8	1.5	0.1	1.9	0.1	-0.3	0.1	1.5	0.4	0.0
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.6	-1.6	-1.4	-0.5	-1.3	-1.0	-0.9	-1.0	0.4	-1.6	-0.6	0.1	1.4	0.2	1.6	-1.3	0.3	1.0	0.1	-1.4
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.5	1.0	0.9	1.1	0.9	0.9	-0.3	0.8	0.9	0.9	0.3	-0.3	-0.0	-1.1	-0.9	0.9	0.5	-0.6	-0.7	1.2
Blood clot in the leg (DVT)	0.4	0.5	4.1	0.0	0.2	-0.5	-0.7	-0.1	-0.8	0.5	-0.2	0.2	-0.4	-0.2	-1.2	0.6	-2.0	0.2	-0.0	-1.1	0.5	-0.2
Medication: Paracetamol	1.2	2.0	6.7	1.1	1.3	0.9	1.3	1.3	-0.7	1.7	-0.5	1.6	-1.1	-2.6	-0.3	-1.8	-0.6	1.3	-1.4	-1.3	-2.2	1.5
Headache pain in last month	0.1	0.1	1.3	0.2	0.1	0.3	0.0	0.1	0.3	0.7	-0.3	0.2	0.2	-0.5	-0.3	-0.2	0.1	0.2	-1.1	0.4	-0.1	0.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	4.0	0.7	0.3	-0.1	0.7	0.7	0.5	-0.1	0.8	0.2	0.7	2.0	1.7	1.0	0.6	0.2	0.4	1.4	0.5	0.2
Glaucoma (self-reported)	0.9	1.1	6.7	0.5	0.5	0.7	0.9	0.7	0.5	1.2	0.3	1.0	0.6	-1.7	1.0	-0.9	-1.4	0.5	-2.6	-0.6	-0.7	0.8
Gout (self-reported)	0.5	0.7	4.4	-0.5	-0.0	-0.4	0.5	0.4	0.5	-0.5	-1.8	-0.5	0.6	0.4	2.1	-1.2	-0.4	-0.0	0.6	-0.0	1.4	-0.6
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	3.5	0.9	1.0	0.7	0.9	0.8	0.3	1.2	1.9	1.3	-0.3	-0.7	-1.2	-0.3	-0.5	1.1	-0.2	-1.0	-1.4	0.9
Medication: Amlodipine	0.1	0.2	1.7	-0.3	-0.3	-0.4	0.2	0.0	-0.1	0.2	-0.1	0.2	-0.2	-0.1	1.3	-0.3	-0.7	-0.3	-0.1	-0.5	-0.1	-0.0
Medication: Ventolin 100micrograms inhaler	5.9	7.6	42.1	0.0	-1.9	-0.9	-0.2	-1.4	0.3	-0.8	6.5	1.1	1.3	1.4	0.9	5.5	3.0	-1.8	-2.1	5.7	-2.8	1.5
Birth weight	1.6	3.5	18.7	-2.0	-1.7	-1.4	-1.7	-2.0	-2.5	-1.3	-0.7	-2.3	-1.5	1.1	-0.9	0.9	1.5	-1.7	4.3	0.5	1.1	-2.5
Chronic bronchitis/emphysema (mother)	1.3	1.5	4.1	1.2	1.2	1.2	1.3	1.2	0.6	1.4	-0.1	1.6	0.3	-2.0	-0.4	-0.7	1.3	1.2	-1.0	-0.7	-1.9	1.7
High blood pressure (siblings)	0.4	0.5	3.9	-0.1	0.4	0.8	0.1	0.4	0.3	0.3	-2.0	-0.1	0.8	-0.4	0.4	-1.3	-1.0	0.5	-0.8	-0.2	0.4	0.1
Forced vital capacity (FVC), Best measure	0.6	2.2	18.0	-0.5	-0.5	-1.0	-0.7	-0.8	-2.0	-1.2	-0.6	-1.1	-2.2	0.9	-1.4	-1.4	1.2	-0.6	4.2	-0.2	-0.8	-1.3
Body fat percentage	0.4	1.4	3.3	1.6	1.2	1.0	1.2	1.3	1.3	1.8	-0.3	1.6	1.4	0.7	0.8	-0.3	-0.7	1.1	-1.6	-0.2	0.5	1.7
Leg fat percentage (right)	0.4	1.4	5.1	1.6	1.0	0.6	1.1	1.1	1.0	1.9	0.3	1.8	0.7	0.3	0.4	-0.4	-1.3	1.0	-2.2	-0.6	-0.3	1.8
Arm fat-free mass (right)	0.4	2.1	9.9	-0.5	-0.8	-1.3	-0.8	-0.8	-3.0	0.2	-1.3	-0.7	-3.1	0.8	0.2	-1.3	0.1	-0.9	2.9	-0.6	-0.9	-1.0
Exposure to tobacco smoke outside home	0.3	0.3	1.1	0.4	0.3	1.0	0.8	0.4	-0.1	0.8	0.2	0.3	0.3	-0.5	0.9	0.6	0.3	0.3	-0.9	0.4	-0.8	0.7
Comparative body size at age 10	0.3	0.8	4.0	-0.5	-0.7	-0.7	-0.8	-0.5	-0.2	0.5	-2.0	-0.5	0.4	1.3	1.0	-1.3	-0.4	-0.7	-0.7	-0.1	1.6	-0.5
Number of full brothers	2.0	2.5	8.1	1.4	1.4	1.3	1.5	1.0	-0.1	1.9	0.8	1.7	-1.3	-2.2	-2.4	-1.2	-0.3	1.5	0.2	-2.2	-2.9	1.8
Worry too long after embarrassment	0.7	1.2	5.7	-0.4	-0.1	0.1	-0.1	-0.2	-1.4	-0.3	-2.4	-0.7	-1.3	-0.8	-0.7	-2.4	1.3	-0.1	1.6	-1.0	-0.6	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	1.7	-1.1	-0.9	-0.2	-0.5	-0.8	-0.6	-1.0	-1.3	-1.1	-0.2	-0.4	0.8	0.2	0.3	-0.9	0.8	0.9	0.2	-1.1
Wheeze or whistling in the chest in last year	5.2	9.3	49.7	-0.5	-2.3	-1.2	-0.5	-1.6	-0.5	-1.2	7.0	0.8	-0.5	-1.3	1.5	5.2	3.6	-2.2	-1.7	5.9	-5.1	1.2
Number of children fathered	0.7	0.8	4.8	-0.5	-0.4	-0.1	0.0	-0.0	1.2	-0.7	0.3	-0.5	0.8	0.8	2.1	-0.2	-2.2	-0.4	-0.5	-0.2	1.3	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.5	-1.2	-0.8	-0.0	-0.7	-0.7	-0.7	-1.6	-1.5	-1.4	0.3	-0.0	0.7	0.6	1.0	-0.7	1.1	1.0	1.0	-1.1
Age at first live birth	1.1	1.9	3.7	-1.9	-1.8	-1.1	-1.7	-1.7	-0.9	-1.9	-0.5	-1.8	-1.0	0.2	0.6	1.2	1.5	-1.8	1.5	1.0	0.5	-1.6
Pulse wave peak to peak time	0.2	0.2	1.2	-0.2	0.1	0.3	0.0	0.2	0.1	-0.2	-1.1	-0.1	-0.4	-0.6	0.4	-1.0	0.5	0.1	0.3	0.3	-0.7	0.1
Health satisfaction	0.9	1.2	4.0	-0.4	-0.5	-1.3	-0.6	-0.8	-1.4	0.0	1.2	0.4	-1.9	-1.3	-1.0	-0.7	-2.0	-0.5	-0.7	-1.7	-1.4	-0.1
Shortness of breath walking on level ground	1.4	1.7	9.3	0.6	0.4	-0.6	0.1	0.4	-0.0	0.2	1.2	1.2	-1.0	-2.0	-0.1	-1.7	-3.0	0.4	-2.2	-1.9	-1.2	0.6
Qualifications: College or University degree	1.5	4.7	12.8	-3.2	-2.8	-2.0	-2.6	-2.7	-2.5	-2.3	-1.0	-3.1	-1.9	0.0	0.6	-0.3	0.9	-2.7	1.8	1.0	1.5	-3.6
Eye problems/disorders: None of the above	0.9	1.0	7.5	1.3	1.0	0.7	0.1	0.5	0.6	0.4	0.3	0.8	1.3	0.7	-2.7	1.1	0.8	1.0	0.4	0.6	0.6	1.0
Mouth/teeth dental problems: Loose teeth	1.3	1.6	3.9	1.8	1.4	1.4	1.6	1.4	1.1	0.9	1.4	1.8	2.0	-0.3	-0.1	0.7	0.1	1.4	-0.8	1.2	-0.2	1.8
Emphysema/chronic bronchitis	2.3	2.6	6.7	-1.6	-2.0	-1.2	-1.5	-2.0	-1.8	-1.7	0.0	-1.5	-1.1	-0.1	-0.5	2.3	2.6	-1.9	1.3	2.4	-0.8	-1.4
Medication for pain relief, constipation, heartburn	1.2	2.1	10.7	-0.4	-0.7	-0.5	-0.1	-0.3	1.5	-1.1	1.7	-0.8	1.7	3.3	2.1	1.1	1.5	-0.7	1.6	1.7	2.1	-0.5
Neck or shoulder pain in last month	0.1	0.1	0.6	-0.3	-0.3	-0.2	-0.3	-0.2	0.4	0.0	-0.2	0.1	0.3	-0.1	0.8	-0.3	-0.4	-0.3	-0.3	0.7	-0.0	0.0
Medication: Blood pressure	0.1	0.2	1.2	-0.4	-0.3	-0.2	-0.6	-0.3	-0.1	-0.0	-0.6	0.0	-0.2	-1.1	-0.3	-0.7	-0.9	-0.2	-0.4	-0.6	0.1	-0.1
Angina (self-reported)	0.8	1.0	5.9	0.4	0.6	0.8	0.0	0.1	-0.1	1.0	0.6	0.5	-0.8	-2.0	-2.4	-1.3	0.1	0.6	-0.3	-0.8	-1.6	0.8
Migraine (self-reported)	0.5	0.6	1.9	-1.4	-0.9	-0.0	-0.7	-0.7	0.2	-0.5	-1.1	-1.3	-0.3	-0.8	1.1	0.4	0.5	-0.9	0.2	0.6	0.0	-1.2
Medication: Ibuprofen	1.2	1.4	5.6	0.5	1.0	0.5	0.4	1.1	-1.1	1.1	-2.4	0.5	-1.4	-2.0	-0.1	-1.3	-1.8	0.9	-0.3	-1.8	-1.1	0.4
Medication: Allopurinol	0.8	1.0	4.6	0.6	1.1	1.1	1.4	1.2	0.4	1.0	-2.1	0.5	0.2	-1.1	0.6	-1.6	1.0	1.1	0.1	-1.1	-0.6	0.6
Medication: Omeprazole	1.6	1.9	9.9	0.8	1.2	1.0	0.9	0.9	0.5	1.6	-1.6	1.1	-0.8	-3.1	-1.1	-1.2	-0.3	1.2	-0.5	-1.7	-2.2	1.1
Medication: Seretide 50 evohaler	4.2	4.8	24.1	-1.4	-2.5	-1.8	-1.2	-2.1	-0.3	-1.9	4.9	-0.8	0.6	0.2	1.2	3.8	1.7	-2.4	-1.7	4.1	-1.0	-0.6
Mean time to correctly identify matches	0.7	1.4	6.2	1.0	1.1	1.0	0.3	0.6	0.9	1.4	-0.5	1.0	0.8	-1.5	-2.5	-0.6	-1.4	1.1	-1.9	-1.1	0.3	1.0
Heart disease (mother)	0.8	1.0	5.4	0.3	0.4	0.3	0.2	0.4	0.9	1.1	-0.7	0.5	0.5	-1.4	0.6	-2.3	-1.2	0.4	-2.2	-0.9	0.6	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.1	2.5	5.5	2.2	2.1	1.6	1.5	1.8	0.8	1.5	1.1	2.1	0.8	-1.3	-1.6	-0.5	-1.4	2.1	-0.7	-1.9	-1.0	2.3
Whole body fat mass	0.1	0.6	2.2	1.1	0.7	0.5	0.8	0.9	0.2	1.5	-0.9	1.0	0.4	0.9	0.9	-0.6	-0.5	0.7	-0.4	-0.2	0.3	1.0
Leg fat mass (right)	0.2	0.7	3.0	1.1	0.7	0.4	0.8	0.9	0.3	1.7	-0.9	1.2	0.1	0.7	1.0	-0.7	-0.6	0.7	-0.9	-0.5	-0.0	1.1
Arm predicted mass (right)	0.3	1.7	8.4	-0.3	-0.7	-1.1	-0.6	-0.6	-2.8	0.4	-1.1	-0.5	-2.9	0.9	0.4	-1.1	0.2	-0.7	2.9	-0.5	-0.9	-0.8
Pulse rate, automated reading	0.2	0.5	2.8	-0.2	-0.3	-0.0	0.3	0.1	-0.4	-0.0	-0.1	-0.1	-1.0	-1.0	1.4	0.5	0.7	-0.3	1.0	1.2	-1.7	0.4
Alcohol intake frequency.	0.8	1.9	5.3	1.7	1.8	1.2	1.1	1.3	1.3	2.1	-0.0	1.8	0.5	-0.6	-2.3	-0.3	-0.7	1.8	-1.0	-1.1	-1.0	1.8
Comparative height size at age 10	0.1	0.7	4.8	0.6	0.3	0.4	0.4	0.1	-0.6	0.4	0.6	0.4	-1.0	0.2	-1.4	-1.2	0.1	0.3	2.2	-1.2	-1.0	0.1
Number of full sisters	0.4	0.5	1.6	0.3	0.6	0.6	0.4	0.4	-0.5	0.4	-0.9	-0.0	-0.9	-0.4	-1.2	-1.0	0.3	0.6	1.2	-0.8	-0.7	0.2
Suffer from ‘nerves’	0.5	0.7	2.3	-0.5	-0.5	-0.6	-0.4	-0.6	-1.4	-0.3	-1.4	-0.9	-0.7	0.8	0.1	-1.5	0.6	-0.6	1.0	-0.5	1.1	-0.8
Overall health rating	0.9	1.8	8.4	0.8	0.9	0.7	0.6	0.4	0.1	2.1	-0.5	1.2	-0.3	-2.9	-2.3	-0.7	-0.3	0.9	-2.2	-1.9	-1.2	1.0
Chest pain or discomfort	1.8	2.6	11.4	-0.8	-1.5	-1.0	-0.8	-1.5	-1.6	-1.5	3.4	-0.2	-1.9	-1.5	-1.0	1.2	1.0	-1.4	-0.6	1.7	-3.3	0.2
Had major operations	0.1	0.1	0.5	0.0	0.1	0.3	0.3	0.1	-0.2	0.5	-0.7	0.0	0.1	-0.6	-0.2	-0.3	-0.4	0.1	-0.2	0.1	-0.3	0.6
Age at last live birth	1.1	1.6	7.7	-1.5	-1.3	-0.4	-0.7	-1.1	-0.4	-1.3	0.4	-1.7	-0.6	0.9	1.2	0.6	2.8	-1.3	2.0	1.3	-0.1	-0.9
Family relationship satisfaction	0.5	0.7	4.0	0.4	0.2	0.3	0.9	0.7	0.4	0.6	0.4	0.6	-0.4	-0.6	2.0	-0.4	-0.6	0.2	-1.6	-0.0	-1.3	0.9
Leg pain on walking	0.5	0.6	2.3	0.0	-0.2	-0.5	-0.4	-0.2	-0.8	0.2	0.4	0.4	-1.2	-1.2	0.2	-1.1	-0.9	-0.2	-1.5	-1.3	-0.6	-0.0
Qualifications: NVQ or HND or HNC or equivalent	4.7	5.7	12.7	3.0	2.8	2.3	3.2	3.1	2.3	3.0	0.6	3.1	1.8	-0.8	0.9	0.1	-1.3	2.8	-3.6	-1.0	-1.8	3.2
Commuting to job workplace: Car/motor vehicle	0.2	0.3	2.2	-0.1	-0.1	-0.1	0.2	-0.1	0.1	-0.3	-0.4	0.1	-0.6	-0.7	-0.3	-1.5	-0.3	-0.0	0.7	-0.9	-0.6	0.1
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	4.7	-0.9	-0.9	-0.7	-0.7	-0.9	-1.1	-1.7	1.2	-1.0	-0.8	0.6	0.3	-2.2	-0.8	-0.9	1.9	-1.5	0.7	-1.0
Medication: Aspirin	0.7	0.9	2.8	1.1	1.0	1.2	0.6	0.7	0.6	1.1	-0.5	1.2	0.1	-0.9	-1.7	-0.5	-1.1	1.0	-1.0	-1.3	-0.4	0.8
Supplements: Vitamin C	2.7	3.2	8.7	1.6	1.9	1.5	1.9	2.0	1.5	1.7	0.1	2.0	0.7	-2.3	1.0	-1.4	-2.4	1.8	-3.0	-2.1	-1.2	1.9
Knee pain experienced in last month	1.0	1.6	4.8	1.1	1.2	1.5	1.8	1.7	1.3	1.1	-2.2	0.9	0.9	-1.0	2.0	-1.4	-0.1	1.2	-0.9	-0.1	-0.5	0.8
Hypertension (Self-reported)	0.5	1.4	3.1	-1.6	-1.1	-1.2	-1.6	-1.3	-1.4	-0.4	-1.8	-1.4	-1.5	-1.7	-0.4	-1.4	-0.3	-1.2	-0.6	-0.5	-0.2	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.3	0.6	0.4	0.5	0.8	0.6	0.2	0.6	0.3	0.6	0.8	0.4	0.9	0.4	-0.3	0.4	-1.2	0.2	0.1	0.7
Illnesses of father: Heart disease	0.4	0.5	4.4	0.4	0.6	0.3	-0.3	0.1	0.2	0.1	-1.5	0.4	0.0	-0.4	-2.1	-0.4	-0.2	0.6	0.2	-0.7	-0.3	0.5
Illnesses of siblings: Diabetes	0.2	0.3	2.9	-0.2	0.3	0.1	0.1	0.4	-0.4	-0.5	-1.7	-0.4	-0.6	-0.1	0.2	-0.6	0.1	0.3	0.9	-0.5	0.1	-0.4
Smoking status: Previous	0.5	0.7	5.2	-0.1	-0.5	-1.0	-0.7	-0.3	-0.4	-0.6	0.9	-0.4	0.1	2.3	0.9	0.3	-0.2	-0.6	1.3	0.9	0.9	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	4.4	1.2	0.8	1.0	1.3	1.0	0.3	1.3	0.9	1.0	-0.3	0.1	-0.2	-0.3	1.2	0.9	1.2	0.4	-2.1	1.0
Whole body fat-free mass	0.3	1.9	10.2	-0.4	-0.7	-1.2	-0.7	-0.6	-2.7	0.2	-1.3	-0.7	-2.8	1.3	0.6	-0.9	0.3	-0.8	3.2	-0.4	-0.5	-1.0
Leg fat-free mass (right)	0.2	1.1	6.7	0.1	-0.0	-0.3	0.2	0.2	-1.6	0.9	-2.1	-0.3	-1.6	1.3	1.1	-0.8	0.5	-0.1	2.6	-0.4	0.2	-0.5
Arm fat percentage (left)	0.3	1.4	3.5	1.6	1.2	0.9	1.2	1.2	1.1	1.9	-0.3	1.5	1.6	1.2	0.7	0.0	-0.7	1.1	-1.3	0.0	0.8	1.6
Average weekly red wine intake	1.3	2.0	4.3	-1.6	-1.6	-1.0	-1.6	-1.5	-1.9	-2.1	0.6	-2.0	-0.5	1.0	0.4	0.5	1.2	-1.5	1.7	0.9	1.3	-1.8
Handedness (chirality/laterality): Left-handed	0.9	1.0	4.2	-0.3	-0.3	0.4	-0.1	-0.3	1.3	-0.1	0.6	-0.2	2.1	1.8	0.4	2.0	0.8	-0.3	-1.3	0.8	1.5	-0.3
Mood swings	0.4	0.7	3.0	0.2	0.4	0.3	0.5	0.3	-0.8	1.1	-1.7	-0.0	-1.0	-1.4	-0.1	-1.5	0.4	0.3	0.3	-1.0	-0.5	-0.0
Loneliness, isolation	0.9	1.2	2.9	1.0	1.0	1.4	1.0	0.6	-0.2	1.2	-1.0	1.1	-0.0	-1.3	-1.4	-1.7	1.6	0.9	-0.4	-0.2	-1.7	1.3
Long-standing illness, disability or infirmity	0.8	1.2	6.9	-0.4	-0.3	0.3	0.7	-0.1	-0.7	0.6	1.6	0.1	-1.4	-2.6	0.9	-0.4	1.4	-0.3	-0.6	0.5	-2.6	0.4
Ever had bowel cancer screening	1.6	1.8	5.4	1.5	1.6	0.9	1.3	1.7	2.3	1.8	0.2	1.2	2.0	1.2	0.9	0.1	-1.2	1.5	-1.1	-0.7	1.4	1.0
Diabetes diagnosed by doctor	0.2	0.4	3.5	-0.6	-0.2	0.6	-0.2	-0.3	-1.1	0.1	-0.4	-0.1	-0.5	-1.9	-0.5	-0.2	0.2	-0.2	-0.5	-0.2	-0.9	0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	5.5	0.4	0.2	0.4	0.0	-0.2	-1.6	-0.2	1.4	0.6	-1.4	-1.2	-2.4	-0.5	-0.4	0.3	1.1	-1.1	-2.1	0.7
Friendships satisfaction	0.4	0.5	1.4	0.7	0.9	0.5	0.6	0.8	0.1	1.0	-1.2	0.3	-0.4	-0.1	-0.0	-1.0	-0.9	0.8	-0.4	-1.1	-0.4	0.3
Qualifications: nursing, teaching	0.3	0.5	3.0	-0.3	-0.3	0.7	0.4	0.2	-0.2	-0.3	1.2	-0.2	-0.2	-1.7	1.5	-0.4	0.3	-0.2	-0.4	-0.0	-0.8	0.1
Commuting to job workplace: Walk	0.3	0.3	1.0	0.6	0.5	0.2	0.6	0.8	-0.5	0.4	1.0	0.5	0.5	0.1	0.9	0.1	-0.4	0.5	-0.4	0.1	0.5	0.6
Eye problems/disorders: Cataract	0.7	0.8	3.5	-1.1	-0.9	-0.8	-0.6	-0.6	-0.5	-1.1	0.2	-0.9	-1.3	0.7	1.9	-0.4	-0.6	-1.0	1.1	-0.2	0.0	-1.4
Mouth/teeth dental problems: Mouth ulcers	6.0	9.6	14.9	3.7	3.8	3.6	3.0	3.0	2.1	3.8	-1.5	3.9	2.4	-2.6	-3.3	-0.8	-2.9	3.7	-3.6	-3.8	-0.6	3.5
Medication for cholesterol	1.0	1.6	6.4	-0.5	-0.9	-0.5	-0.2	-0.5	0.7	-1.4	1.2	-0.7	0.7	1.6	2.0	2.1	1.7	-0.9	1.0	2.5	0.9	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	3.0	0.9	0.5	0.0	0.7	0.6	1.0	1.1	1.1	1.1	0.6	0.6	0.2	1.4	1.7	0.4	-1.4	1.3	-1.3	0.9
Back pain experienced in last month	0.3	0.5	1.6	0.6	0.8	0.6	1.1	0.9	-0.3	0.5	-1.2	0.3	-0.3	-1.3	0.9	-0.4	-0.0	0.7	0.2	-0.1	-0.4	0.3
Mineral and other dietary supplements	0.8	1.1	2.8	1.4	1.2	1.0	0.9	0.8	1.1	1.6	0.3	1.6	0.7	-0.1	-1.4	0.7	0.3	1.1	-1.1	-1.0	-0.3	1.7
Breast cancer (self-reported)	1.1	1.3	3.4	0.8	0.7	0.9	1.5	1.1	1.8	1.1	1.3	1.2	0.9	-0.2	1.8	-0.6	-1.9	0.7	-0.5	-1.0	-1.0	0.9
Asthma (self-reported)	9.7	19.3	134.6	0.2	-2.8	-0.9	0.0	-2.1	-0.2	-1.7	11.6	1.8	0.7	-0.2	1.1	7.3	5.0	-2.8	-1.5	8.3	-6.9	2.5
Osteoporosis (self-reported)	0.9	1.2	10.0	-1.1	-0.9	-0.3	-0.7	-1.1	-0.4	-1.3	-0.1	-0.6	-1.2	-0.3	-0.5	0.8	3.2	-0.9	1.3	0.2	-0.8	-0.7
Osteoarthritis (self-reported)	0.7	1.0	7.1	0.1	0.4	0.4	-0.1	0.3	0.5	-0.4	-1.2	-0.1	0.3	-0.5	-0.3	-2.0	-2.7	0.4	-0.2	-1.6	1.2	-0.5
Medication: Aspirin	0.9	1.1	4.0	1.1	1.0	1.3	0.5	0.6	0.4	1.1	-0.4	1.3	0.1	-1.3	-2.0	-0.6	-1.0	1.1	-1.0	-1.7	-0.6	0.9
Medication: Gliclazide	0.7	0.8	3.3	0.9	0.8	1.1	1.1	0.9	0.9	1.3	0.3	0.7	1.0	-0.1	0.1	1.2	1.8	0.8	-0.3	0.9	-0.1	0.7
Illnesses of father: None of the above (group 1)	0.7	0.9	3.2	-0.5	-0.8	0.3	0.0	-0.5	1.3	-0.9	1.8	-0.7	1.4	1.1	1.5	1.1	0.5	-0.8	-0.3	1.1	0.8	-0.5
Smoking status: Current	0.5	0.8	3.0	-0.3	-0.6	-0.5	-0.4	-1.0	-0.6	-0.4	0.9	-0.7	0.1	0.2	-1.4	1.7	1.0	-0.6	1.2	1.4	0.7	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	14.7	1.1	1.3	0.5	0.9	1.3	0.3	2.2	-3.8	0.7	-0.6	0.4	-0.2	-2.0	0.3	1.3	0.5	-1.4	-0.4	0.1
Whole body water mass	0.3	1.8	9.7	-0.4	-0.8	-1.2	-0.7	-0.7	-2.7	0.2	-1.3	-0.7	-2.7	1.4	0.5	-0.7	0.2	-0.8	3.1	-0.3	-0.4	-1.0
Leg predicted mass (right)	0.2	1.1	6.8	0.1	-0.0	-0.4	0.2	0.2	-1.6	0.9	-2.0	-0.3	-1.6	1.4	1.2	-0.7	0.5	-0.1	2.6	-0.3	0.2	-0.5
Arm fat mass (left)	0.2	0.7	2.7	1.2	0.8	0.5	0.8	0.9	0.1	1.6	-0.9	1.1	0.4	1.0	0.6	-0.3	-0.7	0.8	-0.3	-0.2	0.2	1.2
Number of self-reported non-cancer illnesses	1.2	2.0	13.5	0.5	-0.2	0.4	0.7	-0.1	-0.1	0.7	2.8	1.1	-0.7	-2.4	-0.2	1.4	1.1	-0.1	-1.6	1.1	-3.7	1.3
Average weekly champagne plus white wine intake	1.2	1.6	4.3	-1.4	-1.6	-1.4	-0.7	-1.3	-1.3	-2.1	1.8	-1.1	-1.1	0.8	1.2	0.5	-0.1	-1.6	1.8	0.5	-0.2	-1.5
Miserableness	1.1	1.9	11.1	-0.3	0.4	1.0	0.6	0.1	-1.0	0.6	-1.7	-0.3	-1.6	-3.3	-1.0	-2.8	0.8	0.5	0.6	-1.9	-1.6	0.1
Guilty feelings	1.9	2.8	10.9	1.3	1.8	1.6	1.1	1.1	0.4	1.6	-0.9	1.6	-0.2	-3.3	-3.0	-1.8	-0.3	1.7	-0.7	-2.4	-1.7	1.4
Wears glasses or contact lenses	1.5	1.8	6.2	-1.8	-1.3	-1.3	-1.3	-1.4	-0.6	-0.7	-2.5	-1.9	-1.1	-0.4	0.3	-1.0	-0.7	-1.3	-0.6	-0.7	1.3	-2.2
Ever taken oral contraceptive pill	0.5	0.6	5.2	0.6	0.4	0.8	0.7	0.3	-0.7	0.6	0.2	0.3	-0.1	0.0	-0.7	0.0	2.3	0.5	0.4	0.4	-1.0	0.8
Hearing aid user	2.0	2.3	7.1	-1.9	-1.5	-0.8	-1.3	-1.3	-1.2	-1.6	-1.8	-1.6	-2.7	-2.0	0.6	-1.3	0.8	-1.5	1.2	-0.4	-1.6	-1.7
Mother’s age at death	3.4	4.3	13.2	-2.0	-2.0	-2.0	-1.9	-1.8	0.1	-2.4	0.1	-2.3	1.0	3.6	1.7	1.8	1.0	-2.0	1.2	2.7	3.3	-2.5
Financial situation satisfaction	1.5	1.8	4.4	1.9	1.6	2.1	2.0	1.5	0.9	1.4	1.0	1.8	1.2	-0.5	-0.5	-0.4	0.1	1.7	-0.6	-0.3	-1.2	1.9
Tinnitus: Yes, now most or all of the time	1.0	1.2	7.6	-0.6	-0.3	-0.5	-1.1	-1.0	-1.1	-0.3	-0.7	-0.6	-1.8	-1.6	-2.8	-0.8	0.3	-0.4	0.1	-1.4	-0.9	-0.7
Commuting to job workplace: Public transport	0.6	0.8	4.4	-0.7	-0.8	-0.5	-0.5	-0.4	0.1	-0.4	-0.5	-0.8	-0.4	-0.0	2.0	-0.2	0.8	-0.8	-2.1	0.6	0.2	-1.1
Eye problems/disorders: Glaucoma	0.9	1.1	5.7	-0.4	-0.4	0.2	0.4	0.2	0.3	0.3	0.4	0.2	0.0	-2.0	2.4	-1.4	-1.4	-0.3	-2.2	-0.3	-1.0	0.4
Medication: Blood pressure	0.3	0.6	3.4	-0.8	-0.2	-0.0	-0.5	-0.4	-0.6	-0.1	-1.8	-0.5	-0.8	-0.9	-0.4	-1.6	-0.6	-0.2	-0.8	-1.2	-0.5	-0.2
Pain type(s) experienced in last month: Hip pain	3.4	4.3	9.5	-2.6	-2.8	-3.1	-2.2	-2.5	-2.5	-1.7	0.2	-2.4	-2.0	0.7	1.8	1.5	-0.3	-2.8	0.6	2.5	0.5	-2.6
Supplements: Fish oil (including cod liver oil)	0.8	1.0	3.5	-1.0	-0.9	-0.3	-0.4	-0.6	-1.2	-1.2	0.4	-1.0	-1.3	-1.7	1.0	-1.9	-0.5	-0.8	0.6	-0.1	-1.5	-0.8
High cholesterol (Self-reported)	0.9	1.5	4.0	1.5	1.3	1.2	0.9	0.9	0.6	1.9	0.3	1.6	0.9	-0.2	-2.0	-0.4	-1.0	1.3	-1.9	-1.2	-0.2	1.5
Medication: Bendroflumethiazide	0.9	1.3	5.0	0.6	0.4	-0.4	0.1	0.4	1.4	0.4	-1.8	0.7	2.0	2.2	-0.3	0.6	-1.2	0.4	-1.6	0.6	2.1	0.5
Medication: Paracetamol	1.3	2.0	6.9	0.7	1.1	0.7	1.0	1.1	-1.0	1.7	-0.8	1.3	-1.6	-2.6	0.1	-2.1	-0.6	1.1	-1.3	-1.8	-2.3	1.2
Medication: Lisinopril	0.3	0.4	1.8	-0.2	-0.2	-0.0	-0.2	-0.1	-1.1	-1.0	-0.0	0.2	-0.8	-0.9	0.0	0.0	-0.6	-0.2	-0.7	-0.3	-1.3	0.3
Medication: Atorvastatin	1.0	1.3	3.5	-1.0	-1.3	-1.4	-1.9	-1.6	-1.9	-0.1	0.2	-0.9	-1.3	-0.3	-1.7	-0.2	0.8	-1.3	0.4	1.0	0.0	-1.1
Illnesses of father: High blood pressure	2.0	2.5	10.8	0.7	1.4	1.8	1.0	1.1	0.6	1.7	-1.4	0.6	-0.8	-2.7	-1.6	-3.3	1.0	1.5	-0.3	-2.2	-2.0	1.2
Alcohol drinker status: Never	2.6	3.1	13.7	1.8	1.8	1.7	1.8	1.8	1.4	2.4	0.1	2.0	1.3	-1.3	-0.5	-0.8	-1.6	1.9	-3.7	-1.3	-0.7	2.0
Ever smoked	0.8	1.4	6.3	-0.5	-0.8	-1.1	-1.2	-1.3	-1.3	-1.5	1.0	-0.7	-0.8	1.4	-1.6	1.4	-0.2	-0.9	2.5	0.4	0.7	-1.2
Basal metabolic rate	0.2	1.4	7.2	-0.1	-0.5	-0.9	-0.4	-0.4	-2.4	0.5	-1.3	-0.4	-2.4	1.3	0.5	-0.8	0.1	-0.5	2.7	-0.4	-0.4	-0.7
Leg fat percentage (left)	0.3	1.2	4.3	1.5	1.1	0.5	1.0	1.1	0.9	1.8	0.1	1.8	0.6	0.4	0.2	-0.2	-1.2	1.0	-2.1	-0.6	-0.3	1.8
Arm fat-free mass (left)	0.2	1.2	6.9	0.1	-0.3	-0.8	-0.3	-0.3	-2.3	0.6	-1.1	-0.0	-2.6	0.8	0.0	-0.8	-0.2	-0.4	2.1	-0.6	-1.2	-0.2
Number of operations (self-reported)	1.5	2.3	6.1	1.8	1.6	1.1	1.9	1.5	1.3	1.8	1.0	2.1	0.8	-0.9	-0.6	-0.8	-2.5	1.6	-1.5	-1.3	-1.1	1.8
Average weekly beer plus cider intake	1.2	1.8	4.6	1.8	1.7	1.8	2.1	1.8	0.5	1.5	-0.2	1.7	1.0	-0.8	0.4	-0.9	0.2	1.7	-0.5	-1.3	-0.4	1.7
Irritability	0.6	1.0	2.9	-1.2	-0.7	-1.1	-1.3	-0.6	-1.0	-0.1	-1.7	-1.0	-1.3	-1.1	0.7	-1.4	-1.1	-0.8	-0.4	-0.9	0.6	-1.2
Risk taking	1.5	2.2	7.1	1.6	1.6	1.9	1.6	1.4	0.3	1.1	-1.1	1.4	-0.0	-2.7	-1.1	-2.2	0.3	1.6	-0.0	-1.2	-2.2	1.4
Ever had prostate specific antigen (PSA) test	2.1	2.4	4.8	-1.7	-1.6	-2.1	-1.7	-1.9	-0.8	-1.6	0.4	-1.8	-1.4	2.2	-0.7	1.7	0.6	-1.7	2.0	0.8	1.0	-2.0
Fractured/broken bones in last 5 years	1.3	1.7	4.0	1.6	1.5	1.8	1.9	1.6	2.0	1.5	-0.3	1.3	1.8	-0.2	0.3	0.7	1.2	1.6	0.7	0.1	0.2	1.4
Age started oral contraceptive pill	0.4	0.5	2.3	-0.1	0.6	1.0	0.4	0.5	0.7	0.0	-1.0	-0.1	-0.2	-1.1	-0.5	-1.2	0.5	0.6	1.5	-0.8	-0.7	-0.1
Diastolic blood pressure, automated reading	1.1	3.4	10.7	2.2	2.3	1.7	1.6	1.8	0.6	2.6	-0.8	2.2	0.3	-1.2	-1.6	-2.3	-1.9	2.2	-0.8	-3.3	-0.8	2.0
Ever depressed for a whole week	0.5	0.6	2.0	-0.5	-0.9	-0.7	-0.6	-0.7	0.5	-0.9	1.0	-0.3	0.8	0.1	1.1	0.5	-0.7	-0.9	-1.4	1.0	0.8	-0.5
Unable to work because of sickness or disability	1.7	2.2	4.8	1.9	2.0	2.2	2.0	1.9	1.4	1.6	-0.1	2.1	1.4	-0.9	-0.6	0.7	0.6	2.0	-0.3	-0.2	-0.8	2.2
Commuting to job workplace: Cycle	0.4	0.5	1.9	-0.6	-0.3	-0.0	-0.1	0.1	-0.2	-1.1	-1.2	-0.5	-0.4	-0.2	1.4	0.6	1.3	-0.3	0.2	0.9	-0.1	-0.4
Myopia	0.8	1.1	3.9	-0.6	-1.2	-1.4	-0.9	-1.2	-0.4	-0.5	1.9	-0.4	0.2	1.3	-0.2	2.0	0.7	-1.2	-0.8	1.0	1.2	-0.6
Vascular/heart problems diagnosed by doctor	0.6	1.5	5.0	1.1	0.5	0.6	1.4	0.9	1.0	-0.1	2.2	0.9	1.5	2.2	1.6	1.8	0.9	0.5	1.0	1.3	0.5	0.7
Cholesterol lowering medication	1.0	1.5	5.8	1.3	1.3	0.8	0.9	1.1	1.3	1.6	-0.5	1.6	0.9	-0.3	-1.1	-0.2	-1.6	1.3	-2.4	-1.3	0.1	1.3
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	5.0	0.3	0.9	0.5	0.6	0.6	1.0	1.4	-1.5	0.7	-0.2	-2.2	-0.6	-1.1	-0.7	0.8	-1.2	-1.5	-1.0	0.7
Pain experienced in last month	0.2	0.3	1.8	-0.3	-0.2	-0.2	-0.2	-0.4	-0.3	-0.1	0.3	-0.3	-0.5	0.2	-1.1	-0.4	1.3	-0.2	1.0	-0.7	-0.5	0.1
Supplements: Calcium	0.9	1.0	3.1	1.1	1.2	0.9	1.0	1.0	1.3	1.3	-0.2	0.9	1.8	1.3	-0.3	0.3	-0.7	1.1	0.4	0.0	1.1	0.8
Basal cell carcinoma (self-reported)	2.7	3.2	6.0	-2.3	-2.3	-2.4	-2.5	-2.2	-1.5	-2.1	0.1	-2.3	-1.5	0.6	0.7	0.3	-0.0	-2.3	2.2	0.7	1.4	-2.4
Heart attack/myocardial infarction (self-reported)	0.9	1.1	8.6	0.2	0.2	0.4	-0.4	-0.4	-0.8	0.0	-0.1	0.4	-1.1	-1.4	-2.9	-1.3	-1.4	0.3	0.1	-1.7	-0.9	0.1
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.9	-0.2	-0.0	-0.6	-0.8	-0.4	-1.0	0.2	-0.2	-0.0	-0.6	-0.2	-1.3	0.5	-1.7	-0.1	0.3	-0.9	0.4	-0.4
Heart disease (siblings)	0.3	0.4	2.0	-0.3	-0.3	-0.4	-0.7	-0.6	0.8	-0.3	0.2	-0.3	0.8	0.7	-1.4	-0.6	-0.9	-0.2	-0.0	0.2	0.8	-0.4
Alcohol drinker status: Previous	0.9	1.0	3.3	0.6	1.1	1.2	0.8	0.8	0.2	1.0	-0.4	1.0	0.3	-1.2	-1.8	-0.8	-0.9	1.1	-0.4	-1.5	-1.0	1.1
Pack years of smoking	0.4	0.5	2.1	0.7	0.7	0.2	-0.0	0.5	1.4	0.8	-1.0	0.9	0.8	-0.3	-0.6	-0.3	-0.4	0.7	-0.9	-0.7	1.2	0.5
Impedance of whole body	0.1	0.7	3.9	0.3	0.5	0.8	0.5	0.4	1.8	-1.0	1.4	0.1	2.0	-0.3	-0.6	0.2	0.6	0.5	-0.0	1.1	0.3	0.6
Leg fat mass (left)	0.2	0.6	2.5	1.1	0.6	0.3	0.8	0.8	0.2	1.6	-0.9	1.1	0.1	0.8	0.9	-0.4	-0.4	0.6	-0.8	-0.3	-0.1	1.1
Arm predicted mass (left)	0.2	1.2	7.1	0.0	-0.4	-0.8	-0.4	-0.4	-2.4	0.5	-0.8	-0.0	-2.7	0.7	-0.1	-0.8	0.1	-0.4	2.3	-0.6	-1.3	-0.3