TWAS hub - ITPR1-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.080	0.0380	0.00700	0.022	NA	0.002	NA	0.014	0.0064	NA	0.2300	NA	0.02200
2	GTEx	Lung	0.131	0.0572	0.00960	-0.004	NA	0.031	NA	0.010	0.9500	NA	0.0021	NA	0.05100
3	GTEx	Testis	0.268	0.0890	0.00085	0.046	NA	0.054	NA	0.069	0.0041	NA	0.0021	NA	0.00054

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Medication: Gliclazide	4.1	4.6	7.7	2.8	1.5	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.3	3.9	6.7	-1.2	-1.9	2.6
Medication: Aspirin	3.0	3.9	8.7	2.9	1.1	-1.4
Lung FEV1/FVC ratio	2.8	14.3	34.3	-2.7	-1.1	5.9
Hayfever/allergic rhinitis (self-reported)	2.8	3.7	4.9	-2.2	-2.2	-1.3
Medication: Co-codamol	2.7	3.1	4.2	-1.2	-2.0	1.9
Diabetes (mother)	2.7	3.5	6.4	-1.3	-2.5	1.5
Medication: Lansoprazole	2.7	3.1	5.7	-0.8	-1.7	2.4
Breastfed as a baby	2.7	3.3	9.3	-3.1	-0.3	0.7
Qualifications: A levels/AS levels or equivalent	2.5	5.5	12.1	-3.5	0.2	2.1
Medication: Blood pressure	2.5	4.4	7.3	2.7	1.2	-2.1
Alcohol drinker status: Never	2.5	3.0	7.4	-0.5	-2.7	1.2
Medication: Seretide 50 evohaler	2.4	2.7	6.7	-0.7	-2.6	-1.0
Medication: Ventolin 100micrograms inhaler	2.3	2.9	6.4	-1.6	-2.5	-0.1
Medication: Aspirin	2.3	3.1	7.0	2.6	1.0	-1.1
Other serious medical condition/disability diagnosed by doctor	2.2	2.8	4.5	-2.1	-1.6	1.1
Medication for cholesterol, blood pressure or diabetes	2.2	3.7	7.4	-2.7	-0.8	1.7
Mother’s age at death	2.1	2.6	3.9	0.8	1.8	2.0
Ever had prostate specific antigen (PSA) test	2.1	2.5	5.2	-1.5	-0.0	2.3
HbA1C	2.0	2.2	3.9	1.7	-0.3	-2.0
Cardiovascular Disease	2.0	6.5	11.8	3.4	2.4	-1.5
High blood pressure	2.0	5.7	14.7	3.8	0.5	-1.4
Hypertension (Self-reported)	2.0	5.4	14.2	3.8	0.3	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.9	2.2	2.6	1.6	-1.5	-1.3
Average weekly spirits intake	1.8	2.3	4.1	-0.3	-1.6	2.0
Bipolar Disorder (2011)	1.7	1.7	3.0	0.1	-1.4	-1.7
Heel T-Score	1.7	13.8	21.0	3.7	2.6	-4.6
Current tobacco smoking	1.7	2.8	5.3	-0.9	-2.3	1.5
Financial difficulties in last 2 years	1.7	2.2	4.9	2.2	1.3	0.1
Number of treatments/medications taken	1.6	2.9	4.0	2.0	-1.9	-1.1
Taking other prescription medications	1.6	2.4	3.8	-1.0	-2.0	1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.7	7.4	1.6	1.1	-2.7
Mouth/teeth dental problems: Dentures	1.6	2.7	6.1	0.6	-2.5	-1.2
Vascular/heart problems diagnosed by doctor	1.6	4.4	12.0	-3.5	-0.1	1.1
Systolic Blood Pressure	1.5	7.5	13.5	3.7	2.4	-1.8
Type 2 Diabetes (T2D) (2018)	1.5	2.8	3.9	2.0	1.9	-1.0
Qualifications: nursing, teaching	1.5	2.3	6.4	-2.5	-0.4	0.7
Basal cell carcinoma (self-reported)	1.5	1.7	2.2	-1.2	-1.3	1.5
Heart disease (siblings)	1.5	1.8	5.2	2.3	-0.1	-0.4
Hearing difficulty/problems with background noise	1.4	2.3	6.8	0.1	0.2	2.6
Illnesses of mother	1.4	1.8	4.4	-2.1	-0.9	0.5
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	4.6	1.0	-0.0	-2.1
Age at last live birth	1.4	2.0	3.4	-1.6	-0.1	-1.8
Smoking status: Current	1.4	2.2	4.9	-0.7	-2.2	1.1
Hearing aid user	1.4	1.5	4.2	0.4	0.5	2.1
Pain experienced in last month	1.4	2.3	3.9	-0.6	1.6	-2.0
Mean Putamen Volume	1.3	1.5	2.7	1.4	1.6	0.2
High blood pressure (mother)	1.3	1.8	3.5	1.2	0.5	-1.9
Diabetes (self-reported)	1.3	2.1	2.5	1.5	1.2	-1.6
Alcohol intake versus 10 years previously	1.3	1.9	5.0	-0.8	-2.2	-0.1
Noisy workplace	1.3	1.6	2.9	-1.7	-1.4	0.0
Medication: Cholesterol lowering	1.3	2.0	4.4	2.1	0.5	-1.1
Ever highly irritable/argumentative for 2 days	1.3	1.6	3.0	-0.5	1.2	1.7
Alcohol intake frequency.	1.3	3.1	8.4	0.0	-2.9	-0.9
Commuting to job workplace: Car/motor vehicle	1.3	1.5	3.4	0.3	-1.0	1.8
Commuting to job workplace: Walk	1.3	1.4	2.7	0.2	1.7	-1.1
Illnesses of father: None of the above (group 1)	1.3	1.6	3.5	1.0	1.9	-0.6
Ever used hormone-replacement therapy (HRT)	1.2	1.5	3.3	-1.8	-1.1	0.3
Worrier / anxious feelings	1.2	2.3	7.0	2.6	-0.1	0.2
Pulse wave reflection index	1.2	1.5	3.8	-0.1	-0.8	1.9
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.5	1.7	1.0	-1.3	1.3
Eye problems/disorders: None of the above	1.2	1.4	2.1	-1.5	-1.4	-0.3
Medication: Atorvastatin	1.2	1.4	3.9	2.0	0.1	-0.7
Pack years of smoking	1.2	1.8	4.1	-0.9	-0.6	2.0
Systolic blood pressure, automated reading	1.1	3.1	8.4	2.9	0.1	-0.9
Average weekly fortified wine intake	1.1	1.3	2.5	-1.1	0.5	1.6
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	2.1	-1.2	-1.5	0.6
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	3.4	-1.8	0.1	1.8
Breast cancer (self-reported)	1.1	1.3	2.9	-1.7	0.8	0.7
Commuting to job workplace: Cycle	1.1	1.4	3.3	-0.9	1.8	0.1
Fasting Glucose	1.0	1.2	3.0	0.8	-1.7	0.0
Neuroticism (2016)	1.0	1.5	4.2	0.1	0.5	2.1
Primary Biliary Cirrhosis	1.0	1.5	3.0	-0.6	-1.7	-1.1
Qualifications: CSEs or equivalent	1.0	1.3	3.8	1.9	0.3	-0.4
Chronic bronchitis/emphysema (father)	1.0	1.1	2.8	0.2	-0.8	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	2.3	-0.4	1.5	1.4
Hair/balding pattern: Pattern 4	1.0	2.3	6.8	0.3	-2.6	-0.1
Age at first live birth	1.0	1.8	3.0	-1.7	1.5	0.4
Illnesses of father: Heart disease	1.0	1.3	3.9	-0.3	0.2	2.0
Average weekly red wine intake	1.0	1.5	3.3	-1.8	-1.0	0.6
Tinnitus: Yes, now most or all of the time	1.0	1.1	3.4	0.1	0.1	1.8
Alzheimer’s Disease (in mother)	0.9	1.1	1.8	-0.4	1.1	1.3
Medication for hormone replacement therapy	0.9	1.0	2.0	0.9	0.3	-1.4
Relative age voice broke	0.9	1.4	2.9	1.1	1.7	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	3.6	1.2	1.1	-1.9
Number of live births	0.9	1.3	2.9	-0.8	0.6	-1.7
Prospective memory result	0.9	1.1	2.1	-1.5	1.0	0.5
Length of working week for main job	0.9	1.0	2.7	0.5	-1.6	0.2
Qualifications: College or University degree	0.9	2.7	4.9	-2.2	0.9	1.6
Suffer from ‘nerves’	0.9	1.4	2.2	1.5	0.8	1.1
Overall health rating	0.9	1.9	2.5	-1.0	-1.6	1.5
Leg pain on walking	0.9	1.1	2.4	-0.2	-0.9	1.6
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	1.4	1.0	0.8	-1.2
Mineral and other dietary supplements	0.9	1.2	3.2	-0.4	-1.8	0.3
Number of self-reported non-cancer illnesses	0.9	1.5	3.2	-0.2	-1.8	1.1
Wears glasses or contact lenses	0.9	1.0	2.3	0.8	1.5	-0.3
Eye problems/disorders: Glaucoma	0.9	1.1	2.9	0.2	0.6	1.7
Fractured/broken bones in last 5 years	0.9	1.2	2.5	1.6	0.9	-0.4
Alzheimer’s Disease (including proxy)	0.8	1.2	2.9	0.5	1.7	0.6
Pack years adult smoking proportion	0.8	1.2	3.0	-0.6	-0.3	1.7
Time employed in main current job	0.8	1.0	2.7	1.6	0.4	-0.2
Headache pain in last month	0.8	1.3	2.8	0.7	0.9	-1.7
Glaucoma (self-reported)	0.8	0.9	1.4	-0.1	1.1	1.2
Ever had bowel cancer screening	0.8	1.0	1.8	-0.9	-1.4	0.6
Diabetes diagnosed by doctor	0.8	1.4	3.1	1.0	0.2	-1.8
Medication for cholesterol	0.8	1.2	3.2	-1.8	-0.5	0.0
Asthma (self-reported)	0.8	1.5	3.7	-0.9	-1.9	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	4.2	0.1	0.8	2.0
Medication: Lisinopril	0.8	1.0	2.4	0.6	1.6	-0.5
Unable to work because of sickness or disability	0.8	1.1	2.7	0.4	0.7	1.6
Reaction Time	0.7	1.3	1.6	1.1	1.0	1.3
Age at First Birth	0.7	1.1	1.5	-0.6	-1.2	1.2
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.6	-0.4	-0.6	1.3
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	1.9	-0.8	1.4	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	2.2	-0.8	-0.9	1.5
Happiness	0.7	0.9	2.3	0.2	1.5	-0.6
Depression (self-reported)	0.7	0.9	1.4	-1.0	-0.5	1.2
Number of full brothers	0.7	0.8	1.3	1.1	-0.4	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.8	-0.7	1.4	0.6
Medication: Allopurinol	0.7	1.0	2.5	0.7	-1.6	0.2
Heart disease (mother)	0.7	0.9	1.9	0.5	-1.4	0.7
Knee pain experienced in last month	0.7	1.1	1.8	0.2	-1.3	1.3
Back pain experienced in last month	0.7	1.0	1.8	-0.3	-1.4	1.1
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.5	0.4	1.6	-0.1
High cholesterol (Self-reported)	0.7	1.3	2.3	1.5	0.9	-0.8
Medication: Paracetamol	0.7	1.1	1.8	1.3	-0.7	-1.0
Average weekly beer plus cider intake	0.7	1.0	2.7	0.4	1.6	-0.2
Ever depressed for a whole week	0.7	0.8	1.1	-1.1	0.9	-0.7
Bipolar Disorder (2018)	0.6	0.9	1.4	-1.2	-1.2	0.3
Alzheimer’s Disease (in father)	0.6	0.7	1.7	-0.4	0.3	-1.3
Crohns Disease (2017)	0.6	1.4	2.8	0.1	-1.7	-1.1
Crohns Disease (2012)	0.6	0.9	1.8	-1.3	-1.0	0.2
Blood Eosinophil Count	0.6	4.4	8.7	2.0	0.8	-3.0
Respiratory disease	0.6	1.2	2.7	-0.9	-1.6	-0.4
Chronotype (morning person)	0.6	1.4	3.5	1.9	-0.8	0.1
Frequency of depressed mood in last 2 weeks	0.6	0.8	1.6	0.4	-0.9	1.3
Supplements: Zinc	0.6	0.7	1.4	0.8	-1.2	-0.2
Diabetes (father)	0.6	0.8	1.8	0.1	-0.8	-1.3
Fed-up feelings	0.6	1.1	1.5	1.0	-1.2	0.9
Serious illness, injury or assault to yourself	0.6	0.7	1.6	-1.3	-0.6	0.5
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.5	-0.8	-1.2	-0.1
Had menopause	0.6	0.7	1.5	-0.8	0.2	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	4.2	-0.4	1.2	2.0
Tense / ‘highly strung’	0.6	1.0	1.4	-1.2	-0.9	0.9
Loud music exposure frequency	0.6	0.7	1.4	0.2	-0.7	1.2
Worry too long after embarrassment	0.6	1.1	1.6	1.1	0.6	1.2
Number of children fathered	0.6	0.6	1.8	-0.1	-0.3	1.3
Medication for pain relief, constipation, heartburn	0.6	1.0	1.5	-1.2	1.1	0.6
Neck or shoulder pain in last month	0.6	0.8	1.8	-0.1	-0.8	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.7	0.3	1.3	-0.5
Osteoporosis (self-reported)	0.6	0.7	1.0	-0.8	-1.0	0.7
Commuting to job workplace: Public transport	0.6	0.7	1.4	0.2	-1.2	-0.8
Risk taking	0.6	0.9	1.1	-1.1	0.8	1.0
Age started oral contraceptive pill	0.6	0.8	2.4	-1.6	0.1	0.1
Diastolic blood pressure, automated reading	0.6	1.7	4.4	2.1	-0.1	-0.8
Bipolar Disorder or Schizophrenia	0.5	1.2	3.5	-1.9	-0.4	0.2
Prostate Cancer	0.5	0.7	1.1	1.0	0.9	-0.5
Body Mass Index (BMI) (2010)	0.5	0.6	1.4	1.2	-0.7	0.3
Coronary Artery Disease (CAD)	0.5	0.6	1.3	0.8	1.1	-0.1
Type 2 Diabetes (T2D) (2012)	0.5	0.5	0.9	1.0	0.1	-0.8
Hypothyroidism (self reported)	0.5	1.1	2.0	-1.4	-0.4	1.1
Supplements: Glucosamine	0.5	0.6	0.8	0.9	0.5	-0.9
Medication: Levothyroxine sodium	0.5	0.8	1.0	-1.0	0.9	0.8
Medication: Ramipril	0.5	0.7	0.8	0.9	0.9	-0.7
Medication: Simvastatin	0.5	0.7	1.6	1.3	0.5	-0.6
Fluid intelligence score	0.5	1.0	2.1	0.6	1.5	-0.7
Hair/balding pattern: Pattern 3	0.5	0.8	1.8	1.4	-0.7	-0.0
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	2.5	0.4	1.6	1.5
Asthma	0.5	1.0	2.5	-0.7	-1.6	-0.1
Medication: Amlodipine	0.5	0.7	1.6	1.3	0.5	0.5
Family relationship satisfaction	0.5	0.6	1.7	-1.3	0.2	-0.3
Average weekly champagne plus white wine intake	0.5	0.7	1.1	0.2	-1.1	1.0
Miserableness	0.5	0.9	1.0	-1.0	-0.7	1.0
Guilty feelings	0.5	0.8	1.9	1.4	0.6	-0.0
Number of operations (self-reported)	0.5	0.7	1.1	0.0	-1.0	1.1
Myopia	0.5	0.7	1.8	-1.3	0.6	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	0.8	-0.9	-0.6	0.8
Schizophrenia (2018)	0.4	0.8	2.1	-1.5	0.5	0.0
Breast Cancer	0.4	1.1	1.2	-1.1	1.0	1.0
Rheumatoid Arthritis	0.4	0.6	1.7	-0.1	-1.3	0.0
Triglycerides	0.4	0.6	1.5	1.2	0.5	-0.3
Medication: Metformin	0.4	0.6	1.3	0.5	-0.5	-1.2
Townsend deprivation index at recruitment	0.4	0.5	1.2	0.5	-0.2	1.1
Maternal smoking around birth	0.4	0.5	0.9	0.3	-0.7	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.3	1.1	0.3	-0.1
Number of incorrect matches in round	0.4	0.7	2.2	0.1	-1.5	0.0
Past tobacco smoking	0.4	0.7	1.4	-0.6	0.6	1.2
Qualifications: None of the above	0.4	1.0	2.3	0.5	-0.6	1.5
Pulse wave Arterial Stiffness index	0.4	0.4	0.8	0.9	-0.1	0.6
Birth weight	0.4	0.9	2.5	-0.3	1.6	-0.3
High blood pressure (siblings)	0.4	0.6	1.3	0.5	1.1	-0.4
Exposure to tobacco smoke outside home	0.4	0.5	0.7	0.7	0.7	-0.8
Pulse wave peak to peak time	0.4	0.4	0.9	-0.9	-0.0	-0.6
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.3	-0.3	-0.3	1.1
Medication: Omeprazole	0.4	0.5	0.7	-0.6	0.6	0.8
Mean time to correctly identify matches	0.4	0.8	1.5	0.9	-0.6	1.2
Number of full sisters	0.4	0.5	0.9	-0.2	-0.9	0.8
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	0.7	-0.5	-0.8	0.8
Supplements: Vitamin C	0.4	0.4	1.1	-1.1	-0.4	-0.1
Smoking status: Previous	0.4	0.7	1.1	1.0	-0.1	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.3	-0.3	0.8	1.1
Ever taken oral contraceptive pill	0.4	0.4	1.1	-1.0	-0.4	-0.1
Medication: Blood pressure	0.4	0.7	1.8	1.3	-0.5	-0.1
Ever smoked	0.4	0.7	1.5	-0.3	-1.2	-0.7
Irritability	0.4	0.7	1.6	-0.2	-1.2	-0.7
Cholesterol lowering medication	0.4	0.5	0.7	0.9	0.8	0.5
Depressed Affect (Nagel 2018)	0.3	0.7	1.5	-0.5	-1.2	0.4
Depression (Nagel 2018)	0.3	0.4	0.7	0.5	0.5	0.9
Worry (Nagel 2018)	0.3	0.7	1.3	1.2	0.5	0.7
Verbal and Numeric Reasoning (VNR)	0.3	0.8	2.5	-0.1	1.6	0.2
LDL Cholesterol	0.3	0.4	1.0	0.3	0.3	-1.0
Lupus	0.3	0.4	1.0	-0.3	1.0	-0.4
Schizophrenia (2014)	0.3	0.7	1.1	-1.1	0.4	-1.0
Smoking Status	0.3	0.6	1.8	0.2	-1.4	0.3
Sensitivity / hurt feelings	0.3	0.4	0.6	0.8	-0.7	0.5
Hearing difficulty/problems: Yes	0.3	0.5	1.0	0.4	0.5	1.0
Vitamin and mineral supplements	0.3	0.4	0.7	-0.5	0.4	0.8
Multivitamins +/- minerals	0.3	0.3	0.6	0.6	0.3	-0.8
Stomach or abdominal pain in last month	0.3	0.3	0.5	-0.7	0.6	0.2
Medication: Atenolol	0.3	0.4	0.9	-0.4	-0.9	-0.1
Nervous feelings	0.3	0.5	1.1	1.0	0.6	0.3
Had other major operations	0.3	0.4	0.5	-0.2	0.7	0.7
Mouth/teeth dental problems	0.3	0.5	0.9	-0.3	1.0	0.7
Neuroticism score	0.3	0.7	1.2	1.0	0.0	1.1
Impedance of arm (right)	0.3	1.4	2.7	0.1	1.6	-1.2
Father’s age at death	0.3	0.4	0.8	-0.9	0.5	-0.0
Lung cancer (father)	0.3	0.3	0.7	-0.8	-0.0	-0.5
Peak expiratory flow (PEF)	0.3	0.8	1.4	0.6	0.7	1.2
Gout (self-reported)	0.3	0.4	1.1	1.1	-0.0	-0.2
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.7	-0.7	0.0	0.8
Health satisfaction	0.3	0.3	1.0	0.0	-1.0	0.2
Migraine (self-reported)	0.3	0.3	0.7	-0.1	-0.5	-0.8
Loneliness, isolation	0.3	0.5	0.7	0.8	-0.0	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	0.6	0.3	-0.8	-0.6
Osteoarthritis (self-reported)	0.3	0.4	0.5	-0.6	-0.6	0.7
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.7	-0.9	-0.1	0.6
Schizophrenia vs Biploar Disorder	0.2	0.3	0.7	-0.3	0.2	-0.8
Ulcerative Colitis	0.2	0.3	0.6	-0.8	0.1	-0.5
Blood Platelet Count	0.2	2.2	3.6	1.8	-0.1	-1.9
Blood Red Count	0.2	1.9	3.1	-1.4	-1.8	0.7
Neuroticism	0.2	0.4	1.3	-0.2	-0.0	1.1
Ever had hysterectomy (womb removed)	0.2	0.3	0.6	0.4	0.3	-0.8
Impedance of leg (right)	0.2	0.8	1.8	0.1	0.8	-1.3
Hand grip strength (right)	0.2	0.6	0.7	-0.7	0.8	0.8
Age when periods started (menarche)	0.2	0.4	0.8	-0.9	0.6	0.1
Sitting height	0.2	1.2	1.6	1.1	0.9	-1.3
Impedance of leg (left)	0.2	0.8	1.5	-0.2	0.9	-1.2
Hair/balding pattern: Pattern 2	0.2	0.3	0.7	-0.2	0.8	0.4
Forced vital capacity (FVC)	0.2	0.7	1.1	0.3	1.0	1.1
Heart attack	0.2	0.3	0.5	-0.7	0.1	0.5
Allergy	0.2	0.5	0.9	0.9	0.6	-0.4
Pain all over the body in last month	0.2	0.2	0.3	0.6	-0.4	-0.3
Illnesses of siblings	0.2	0.3	0.5	0.3	0.7	0.6
Falls in the last year	0.2	0.3	0.6	-0.8	-0.6	0.1
Impedance of arm (left)	0.2	1.0	1.6	-0.6	1.3	-1.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.6	-0.8	0.5	0.4
Wheeze or whistling in the chest in last year	0.2	0.4	0.6	-0.4	-0.7	-0.8
Medication: Ibuprofen	0.2	0.2	0.4	0.5	-0.7	-0.1
Pulse rate, automated reading	0.2	0.8	1.7	0.4	-1.3	-0.7
Had major operations	0.2	0.2	0.4	0.2	0.6	0.4
Illnesses of siblings: Diabetes	0.2	0.3	0.8	0.2	-0.9	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.7	-0.7	0.9	-0.0
Mood swings	0.2	0.4	0.5	-0.7	-0.6	-0.5
Long-standing illness, disability or infirmity	0.2	0.4	0.7	0.6	-0.9	0.2
Friendships satisfaction	0.2	0.3	0.7	0.3	0.3	-0.8
Financial situation satisfaction	0.2	0.2	0.5	0.3	-0.2	-0.7
Medication: Bendroflumethiazide	0.2	0.2	0.5	0.7	-0.4	-0.1
Illnesses of father: High blood pressure	0.2	0.2	0.4	-0.5	0.0	0.6
Impedance of whole body	0.2	0.8	1.1	-0.6	1.1	-1.0
Intelligence (Savage-Jansen 2018)	0.1	0.5	0.7	0.9	0.8	-0.3
Neuroticism (Nagel 2018)	0.1	0.1	0.2	0.4	-0.3	0.4
Irritable Bowel Disease (IBD)	0.1	0.1	0.2	-0.3	-0.5	-0.3
Ulcerative Colitis (UC)	0.1	0.2	0.5	-0.4	0.7	0.0
Major Depression (MDD)	0.1	0.1	0.2	0.3	-0.4	0.4
HDL Cholesterol	0.1	0.2	0.3	-0.0	0.4	0.5
Height	0.1	1.2	2.7	-1.6	-0.3	0.8
Allergy or Eczema	0.1	0.2	0.3	-0.4	-0.5	-0.0
Lung FVC	0.1	0.3	0.6	0.1	-0.7	0.8
Relative age of first facial hair	0.1	0.3	0.7	-0.1	0.2	-0.9
Angina	0.1	0.1	0.3	0.5	-0.1	-0.1
Leg fat-free mass (left)	0.1	0.3	0.7	0.5	-0.0	0.9
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.4	-0.6	-0.3	-0.1
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.3	0.0	0.6	-0.5
Body mass index (BMI)	0.1	0.3	0.4	0.6	-0.2	0.7
Leg predicted mass (left)	0.1	0.3	0.7	0.5	-0.1	0.8
Waist circumference	0.1	0.5	1.3	-0.2	-0.5	1.1
Alcohol usually taken with meals	0.1	0.1	0.4	-0.6	0.1	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	0.6	-0.3	0.4
Weight	0.1	0.3	0.6	0.6	0.1	0.8
Arm fat percentage (right)	0.1	0.3	0.5	0.6	-0.2	0.7
Trunk fat-free mass	0.1	0.4	0.6	0.7	0.1	0.8
Hip circumference	0.1	0.5	1.3	0.5	0.2	1.1
Pulse rate	0.1	0.2	0.3	0.6	-0.4	-0.4
Arm fat mass (right)	0.1	0.4	0.7	0.9	-0.4	0.4
Trunk predicted mass	0.1	0.4	0.6	0.7	0.2	0.8
Birth weight of first child	0.1	0.3	0.6	-0.3	-0.8	-0.4
Blood clot in the leg (DVT)	0.1	0.1	0.2	0.5	0.0	0.1
Medication: Paracetamol	0.1	0.2	0.5	0.1	-0.7	-0.4
Forced vital capacity (FVC), Best measure	0.1	0.5	1.1	-0.1	0.7	1.0
Leg fat percentage (right)	0.1	0.3	0.4	0.6	-0.2	0.7
Arm fat-free mass (right)	0.1	0.3	0.6	0.4	-0.5	0.8
Comparative body size at age 10	0.1	0.4	1.0	0.2	0.0	1.0
Emphysema/chronic bronchitis	0.1	0.1	0.1	-0.3	-0.0	0.3
Leg fat mass (right)	0.1	0.3	0.5	0.7	-0.4	0.5
Arm predicted mass (right)	0.1	0.3	0.6	0.8	-0.1	0.6
Comparative height size at age 10	0.1	0.5	1.0	-0.3	-0.7	1.0
Chest pain or discomfort	0.1	0.2	0.5	0.2	-0.7	-0.2
Whole body fat-free mass	0.1	0.4	0.9	0.6	-0.1	1.0
Leg fat-free mass (right)	0.1	0.4	1.1	0.5	-0.0	1.0
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	-0.2	-0.5	-0.4
Eye problems/disorders: Cataract	0.1	0.1	0.3	0.3	0.5	-0.1
Whole body water mass	0.1	0.4	0.8	0.7	-0.0	0.9
Leg predicted mass (right)	0.1	0.4	0.9	0.5	-0.0	0.9
Arm fat mass (left)	0.1	0.2	0.5	0.7	-0.3	0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.1	0.2	-0.3	0.2
Basal metabolic rate	0.1	0.4	0.7	0.8	0.0	0.8
Leg fat percentage (left)	0.1	0.3	0.5	0.5	-0.1	0.7
Arm fat-free mass (left)	0.1	0.4	0.8	0.7	-0.3	0.9
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.4	0.6	0.1	0.1
Alcohol drinker status: Previous	0.1	0.1	0.2	0.4	-0.3	-0.5
Leg fat mass (left)	0.1	0.2	0.4	0.7	-0.3	0.5
Arm predicted mass (left)	0.1	0.4	0.7	0.8	-0.1	0.7
Ovarian Cancer	0.0	0.0	0.1	-0.2	0.2	-0.2
Blood White Count	0.0	0.4	0.8	-0.2	-0.9	-0.5
BMI	0.0	0.0	0.1	0.3	0.1	0.2
Waist Hip Ratio (WHR)	0.0	0.0	0.0	-0.1	0.2	-0.0
Hair Pigment	0.0	0.4	1.0	0.3	-1.0	0.5
Tanning	0.0	0.2	0.3	-0.4	-0.5	-0.4
Hand grip strength (left)	0.0	0.1	0.2	0.2	0.4	0.0
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.1	0.1	0.3	-0.1
Severe depression (siblings)	0.0	0.0	0.1	-0.1	-0.1	-0.4
Trunk fat percentage	0.0	0.1	0.2	0.2	0.1	0.4
Trunk fat mass	0.0	0.2	0.4	0.4	-0.1	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.1	0.0	-0.2	0.3
Standing height	0.0	0.2	0.6	0.3	0.8	0.2
Exposure to tobacco smoke at home	0.0	0.0	0.0	0.1	-0.0	-0.1
Body fat percentage	0.0	0.2	0.3	0.3	-0.3	0.6
Shortness of breath walking on level ground	0.0	0.0	0.0	-0.2	0.1	0.2
Angina (self-reported)	0.0	0.0	0.1	0.4	0.0	-0.1
Whole body fat mass	0.0	0.2	0.3	0.6	-0.1	0.4
Arm fat percentage (left)	0.0	0.2	0.2	0.4	-0.3	0.5
Supplements: Calcium	0.0	0.0	0.0	0.1	-0.0	-0.2

Hub : Genes

ITPR1-AS1

Models

Trait associations