TWAS
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Traits
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Traits
:
Lung FEV1/FVC ratio
:
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chr3:54,802,351-56,217,454
Best TWAS P=2.94e-12 · Best GWAS P=1.65e-33 conditioned to 3.98e-36
54.8M
55M
55.2M
55.4M
55.6M
55.8M
56M
56.2M
0
10
20
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Pancreas
WNT5A
0.2
0.2
lasso
2
0.18
3.9e-08
-6.9
-7
2.9e-12
-0.07
0.96
0
TRUE