Best TWAS P=1.75e-07 · Best GWAS P=1.65e-07 conditioned to 0.296
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | U2SURP | 0.10 | 0.06 | lasso | 4 | 0.04 | 0.00015 | 5.2 | 5.2 | 2.0e-07 | 0.98 | 0.02 | 0.98 | FALSE |
| 2 | METSIM | Adipose | RP11-91G21.1 | 0.05 | 0.03 | lasso | 5 | 0.03 | 0.00002 | 4.3 | -5.2 | 2.1e-07 | -0.94 | 0.02 | 0.97 | FALSE |
| 3 | METSIM | Adipose | U2SURP | 0.04 | 0.02 | lasso | 4 | 0.01 | 0.00546 | 5.2 | 5.2 | 1.7e-07 | 0.93 | 0.02 | 0.97 | TRUE |