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Lung FEV1/FVC ratio
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chr3:141,992,282-143,476,411
Best TWAS P=1.75e-07 · Best GWAS P=1.65e-07 conditioned to 0.296
142M
142.2M
142.4M
142.6M
142.8M
143M
143.2M
143.4M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
METSIM
Adipose
U2SURP
0.04
0.02
lasso
4
0.01
0.00546
5.2
5.2
1.7e-07
0.93
0.02
0.97
TRUE
1
GTEx
Skin Sun Exposed Lower leg
U2SURP
0.10
0.06
lasso
4
0.04
0.00015
5.2
5.2
2.0e-07
0.98
0.02
0.98
FALSE
2
METSIM
Adipose
RP11-91G21.1
0.05
0.03
lasso
5
0.03
0.00002
4.3
-5.2
2.1e-07
-0.94
0.02
0.97
FALSE