Hub : Genes

FRAS1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.261	0.0520	2.7e-11	0.032	0.124	0.143	0.151	0.104	7.4e-05	7.8e-15	5.3e-17	5.1e-18	1.3e-12
2	GTEx	Artery Aorta	0.267	0.0860	7.5e-04	-0.003	NA	0.007	NA	0.005	5.4e-01	NA	1.3e-01	NA	1.6e-01
3	GTEx	Breast Mammary Tissue (Male)	0.219	0.1787	1.7e-01	-0.012	NA	-0.012	NA	-0.011	7.4e-01	NA	8.0e-01	NA	7.3e-01
4	GTEx	Cells Transformed fibroblasts	0.213	0.0640	2.8e-04	0.004	NA	0.011	NA	0.001	1.6e-01	NA	5.0e-02	NA	2.9e-01
5	GTEx	Colon Sigmoid	0.187	0.0870	7.3e-03	0.012	NA	0.005	NA	0.002	1.2e-01	NA	2.0e-01	NA	2.8e-01
6	GTEx	Heart Atrial Appendage	0.236	0.0690	7.5e-05	0.011	NA	0.048	NA	0.056	1.0e-01	NA	3.2e-03	NA	1.6e-03
7	GTEx	Muscle Skeletal	0.113	0.0384	1.3e-05	0.060	NA	0.076	NA	0.075	1.5e-06	NA	6.3e-08	NA	7.8e-08
8	GTEx	Nerve Tibial	0.361	0.0691	1.8e-14	0.178	NA	0.283	NA	0.272	1.2e-12	NA	2.8e-20	NA	1.9e-19
9	GTEx	Spleen	0.748	0.0730	1.2e-06	-0.010	NA	0.284	NA	0.239	7.4e-01	NA	5.6e-08	NA	8.1e-07
10	GTEx	Stomach	0.114	0.0530	5.2e-03	-0.005	NA	0.013	NA	0.007	7.4e-01	NA	7.7e-02	NA	1.5e-01
11	ROSMAP	Brain Pre-frontal Cortex	0.246	0.0475	1.2e-14	0.029	0.125	0.126	0.135	0.110	1.1e-04	9.2e-16	7.3e-16	5.1e-17	5.0e-14
12	TCGA	Brain Lower Grade Glioma	0.108	0.0348	1.9e-06	0.052	0.054	0.064	NA	0.046	1.5e-06	9.6e-07	8.7e-08	NA	5.5e-06
13	TCGA	Ovarian Serous Cystadenocarcinoma	0.092	0.0380	3.8e-04	0.042	0.036	0.029	NA	0.045	7.4e-04	1.8e-03	4.2e-03	NA	5.1e-04
14	TCGA	Prostate Adenocarcinoma	0.037	0.0179	7.8e-03	0.017	0.016	0.005	NA	0.028	6.1e-03	7.8e-03	9.4e-02	NA	5.2e-04
15	TCGA	Thyroid Carcinoma	0.132	0.0580	1.6e-03	0.051	0.024	0.034	NA	0.037	9.5e-06	2.1e-03	2.5e-04	NA	1.5e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	0.3	0.5	1.5	-0.4	0.7	0.9	0.3	0.8	-1.1	-0.5	0.8	-0.4	-0.7	-0.3	-0.6	-0.6	0.4	-1.2
Bipolar Disorder or Schizophrenia	0.4	1.0	3.3	1.8	0.5	0.9	-0.4	0.8	-0.7	-0.1	0.0	-0.1	-1.4	1.0	0.7	-1.7	-0.9	-1.4
Depressed Affect (Nagel 2018)	1.2	2.4	10.6	0.2	1.3	1.4	-0.1	3.3	0.4	-2.2	2.5	0.3	0.1	2.2	-0.8	2.2	0.6	-0.3
Depression (Nagel 2018)	0.3	0.5	2.3	-0.3	0.6	1.5	0.6	0.8	-0.3	-1.0	-0.1	0.2	0.2	-0.3	0.1	0.5	0.7	-1.4
Intelligence (Savage-Jansen 2018)	0.4	1.2	4.8	0.0	0.1	0.8	1.2	0.3	0.1	0.3	-0.5	-0.5	2.1	-0.5	-0.2	-1.4	1.9	2.2
Neuroticism (Nagel 2018)	0.7	1.7	5.8	0.4	1.2	1.8	-0.8	2.4	0.2	-1.5	2.1	0.9	-0.1	1.9	-0.4	1.6	0.4	-0.1
Schizophrenia (2018)	0.7	1.4	7.0	2.6	0.3	0.4	-0.9	0.4	-0.0	0.4	-0.7	0.3	-1.2	1.6	1.5	-1.7	-1.5	-0.8
Schizophrenia vs Biploar Disorder	0.8	1.1	4.7	1.4	-0.0	-2.2	-0.8	-0.2	-0.3	1.1	-0.7	1.0	-0.9	1.2	0.8	-0.6	-1.6	1.0
Worry (Nagel 2018)	0.3	0.6	3.0	1.5	0.9	0.9	-0.3	0.8	-0.4	-0.3	0.4	0.6	-0.9	1.7	0.2	0.3	-0.1	-0.6
Alzheimer’s Disease (in mother)	1.0	1.2	3.1	1.8	-1.2	0.9	-0.9	-0.1	1.5	0.3	-0.7	0.2	-1.4	1.6	0.4	0.1	-1.1	1.7
Alzheimer’s Disease (in father)	0.8	0.9	2.8	0.8	1.1	-1.7	1.2	0.5	1.0	0.1	0.6	-0.3	-0.3	0.4	-1.4	1.0	-0.4	1.4
Alzheimer’s Disease (including proxy)	0.4	0.7	2.2	1.3	-0.4	0.0	-0.4	0.5	0.9	-0.1	0.2	0.3	-1.2	1.1	-0.4	0.1	-1.5	1.2
Crohns Disease (2017)	1.1	2.4	9.9	-0.1	0.8	-0.4	-1.8	1.0	-0.2	-2.0	3.1	0.8	1.5	0.8	-1.7	2.3	1.2	-2.1
Irritable Bowel Disease (IBD)	0.7	1.6	5.0	0.0	0.3	-1.5	-0.5	1.4	-0.6	-1.0	2.2	0.9	1.8	1.6	-0.9	1.7	0.5	-1.7
Ulcerative Colitis (UC)	0.3	0.6	2.1	0.1	-0.2	-1.3	0.3	1.1	-0.8	-0.3	0.7	0.5	1.4	1.0	-0.2	0.4	-0.3	-0.9
Major Depression (MDD)	0.5	0.6	1.3	-0.8	0.6	-0.2	-0.6	0.4	0.9	0.2	1.1	-1.1	0.1	-1.0	1.0	-1.1	0.8	0.1
Reaction Time	0.4	0.7	1.8	0.9	-1.3	-0.1	-1.1	-1.2	0.6	1.0	0.1	0.8	-0.3	0.5	1.1	-1.1	-0.3	0.5
Verbal and Numeric Reasoning (VNR)	0.5	1.1	6.4	-1.0	-0.4	-0.0	0.9	1.4	-0.7	-0.4	0.3	-0.5	2.5	-0.5	-0.6	-0.5	1.9	0.9
Breast Cancer	0.4	0.9	3.4	1.2	0.9	0.8	-0.8	1.5	0.7	-1.8	0.6	0.6	0.2	1.0	-0.7	0.7	-0.6	0.8
Ovarian Cancer	0.9	1.2	3.7	-1.2	-0.6	1.2	1.4	-0.8	0.1	-1.0	1.4	-1.9	0.1	-0.1	-1.8	1.1	0.3	0.8
Prostate Cancer	0.8	1.1	7.1	-1.2	0.4	-0.8	0.2	-2.7	0.4	-0.3	-0.0	-0.8	-0.5	-1.7	-1.2	1.3	-0.6	0.5
Age at First Birth	0.4	0.7	2.2	-0.4	0.5	-0.6	0.7	0.4	1.5	-0.6	0.8	0.8	0.8	0.9	0.2	0.3	0.9	1.5
Bipolar Disorder (2011)	0.8	0.8	3.4	-1.4	0.8	0.6	0.2	1.2	-1.4	-0.3	0.3	-0.6	-0.7	-1.0	-0.4	-0.0	-0.1	-1.8
Body Mass Index (BMI) (2010)	0.1	0.2	1.1	-0.2	0.3	1.1	-0.1	-0.3	-0.6	0.4	-0.1	0.4	-0.3	-0.1	0.1	0.5	0.1	-0.7
Coronary Artery Disease (CAD)	0.5	0.6	2.5	1.6	-0.9	-0.3	0.8	-0.5	-0.7	0.2	-0.1	-0.9	0.3	0.1	-0.0	-1.1	1.1	-0.5
Crohns Disease (2012)	0.6	1.0	5.1	0.1	1.2	0.1	-1.0	0.0	1.6	-0.0	1.4	1.5	0.4	0.3	-0.9	2.3	0.3	-0.3
Mean Putamen Volume	1.2	1.4	5.6	0.8	-2.1	2.4	-0.8	-1.1	1.5	0.8	-0.8	-1.0	1.0	-1.1	0.1	-0.1	0.5	1.4
Fasting Glucose	0.8	1.0	3.5	-0.3	-0.4	-0.7	0.7	-0.5	1.4	1.7	-1.5	0.7	-0.4	-1.9	0.4	-0.6	-1.0	0.3
HbA1C	0.4	0.4	2.1	0.4	1.4	1.2	0.7	0.7	-0.3	0.2	-0.4	-0.8	0.6	0.6	-0.2	-0.5	0.2	0.2
HDL Cholesterol	0.2	0.4	1.7	-0.1	0.7	0.6	0.7	-0.6	0.7	-0.3	-0.0	-0.6	0.7	0.6	0.1	-0.4	0.6	1.3
LDL Cholesterol	1.8	2.8	14.4	-0.1	-1.3	0.9	1.5	-3.0	-1.1	1.2	-3.8	0.1	-0.9	-2.8	0.3	-1.1	-0.6	-0.9
Lupus	0.5	0.8	3.0	-0.5	0.4	0.8	-1.0	-0.1	-1.7	0.3	-1.0	0.5	-0.0	-1.0	-0.0	-0.7	1.1	-1.7
Neuroticism (2016)	0.6	0.8	3.4	-0.6	-1.8	0.1	-1.2	0.7	-0.7	1.3	-0.2	0.4	1.3	-1.5	-0.2	0.4	0.3	-0.6
Primary Biliary Cirrhosis	0.7	1.0	2.8	1.7	-0.8	1.6	-1.5	0.0	1.3	0.9	-0.7	0.7	-0.1	-0.2	0.3	-0.7	-0.1	1.7
Rheumatoid Arthritis	0.6	0.9	3.6	0.1	0.5	0.1	-0.0	-0.8	1.2	-1.8	0.2	-1.1	0.8	-0.3	-1.9	0.4	-0.2	1.4
Schizophrenia (2014)	0.8	1.8	8.5	2.9	0.0	1.1	-1.1	0.2	0.3	0.6	-0.5	1.6	-1.5	1.7	1.1	-1.2	-2.1	-0.5
Triglycerides	0.6	1.0	3.9	2.0	0.2	-0.7	-0.3	-0.8	0.9	2.0	-1.0	1.0	-1.4	-0.1	0.8	-0.5	-0.2	-0.0
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.3	-0.0	0.5	0.4	1.4	-0.7	1.1	-1.0	0.0	-1.5	-0.3	-1.1	-1.3	0.7	0.2	0.6
Ulcerative Colitis	0.6	0.8	5.1	0.7	-0.0	-0.1	0.1	0.7	0.3	0.2	-0.5	2.2	0.2	0.8	-0.5	1.5	-1.5	-0.4
Blood Eosinophil Count	0.1	1.1	4.9	0.3	-0.3	1.3	0.5	0.2	-1.0	-0.6	-0.6	0.7	2.2	-0.1	-1.1	0.9	1.6	-1.7
Blood Platelet Count	0.1	1.7	6.7	1.1	-0.2	0.2	-1.0	-0.5	2.3	-1.5	0.2	-1.7	-0.3	1.8	1.3	0.3	-2.6	0.0
Blood Red Count	0.7	7.0	16.5	1.4	-2.5	0.3	2.6	-4.1	2.5	3.9	-2.9	-2.5	-1.0	-2.6	2.7	-4.0	-0.7	2.5
Blood White Count	0.4	2.8	11.6	2.3	0.7	0.2	1.3	-3.4	1.5	-1.3	-0.3	-3.1	1.6	0.8	0.2	-1.2	1.8	0.8
Heel T-Score	0.4	3.0	12.0	-0.4	0.3	3.5	-0.3	1.1	-0.9	-1.6	1.6	1.3	3.2	-0.1	-2.6	1.1	2.1	-0.7
BMI	0.7	4.3	16.9	3.3	0.7	0.7	0.0	-0.9	-1.1	0.5	-1.6	-1.4	-4.1	2.5	3.2	-1.8	-2.0	-2.3
Height	0.1	2.5	7.5	1.8	-2.1	-2.1	-1.3	-0.0	1.3	1.9	-0.8	-0.1	-0.6	0.6	2.7	-2.5	-0.5	1.6
Waist Hip Ratio (WHR)	0.5	2.2	6.8	1.7	1.8	0.5	-0.8	-0.2	0.4	-0.6	-2.4	-1.3	-2.6	0.3	1.4	-0.4	-2.6	-1.6
Systolic Blood Pressure	0.6	2.9	8.2	0.5	0.8	-0.6	1.9	-2.5	2.7	-1.7	0.1	-2.6	-0.0	-1.9	-1.8	0.3	-0.5	2.9
Smoking Status	0.4	1.0	4.4	-0.8	1.4	0.3	-0.6	0.2	-0.9	-2.1	0.9	-1.6	-0.5	0.3	0.1	-0.7	0.8	-1.1
Allergy or Eczema	0.4	1.1	4.2	-1.8	0.3	2.1	0.6	0.2	0.1	-0.6	0.4	-0.4	0.3	-0.9	-1.1	1.5	0.5	-1.8
Cardiovascular Disease	0.2	0.7	2.9	0.9	0.6	1.7	0.1	-0.4	1.0	-1.2	0.8	-1.0	-0.2	1.2	-0.2	0.5	0.4	0.5
Hypothyroidism (self reported)	0.4	0.9	4.3	1.9	0.2	1.3	-0.1	0.4	1.1	0.3	0.3	0.7	-0.6	2.1	1.0	0.0	-0.2	0.8
Respiratory disease	0.6	1.3	4.0	0.1	-0.2	1.7	-1.9	0.8	2.0	-1.1	2.0	0.7	0.8	0.4	0.9	-0.5	-0.2	-0.3
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.8	1.2	1.6	-0.2	-0.5	-0.1	1.7	-0.3	-0.0	0.5	-0.3	1.4	-0.3	1.3	-0.4	0.3
Lung FEV1/FVC ratio	1.6	7.9	44.9	-0.0	-0.3	0.9	3.6	-3.8	-4.2	1.3	-1.6	-2.8	2.5	-1.6	0.8	-2.5	6.7	-1.3
Lung FVC	0.2	1.2	7.6	-1.2	1.0	-2.8	-0.3	0.5	-0.1	-1.2	-0.1	-0.4	-0.4	-1.8	-0.3	-0.5	1.4	0.8
Neuroticism	0.5	1.3	5.5	0.4	0.9	1.3	0.3	2.3	-0.9	-1.5	0.7	0.5	0.0	1.6	-0.8	1.7	0.5	-1.1
Chronotype (morning person)	0.4	1.0	3.3	-0.2	-0.9	0.1	-0.4	1.8	-0.6	-0.9	0.5	1.8	1.0	-0.4	-0.5	1.7	0.3	-1.0
Hair Pigment	2.0	57.7	237.2	-4.5	0.9	4.4	-7.0	10.5	0.8	-13.1	15.4	-1.8	7.0	4.3	-7.4	9.5	6.1	-1.8
Tanning	0.1	0.6	1.9	-0.1	0.8	-1.4	1.2	-0.0	1.0	-0.2	-0.6	-0.8	-1.4	-0.8	-0.2	-0.4	-0.3	-0.6
Hand grip strength (left)	0.2	0.5	2.0	-0.2	1.0	-1.4	-0.2	-0.8	0.0	-0.5	1.0	-1.0	0.1	-0.5	-1.2	-0.2	0.4	0.3
Number of treatments/medications taken	0.4	0.7	2.2	1.4	-0.5	0.7	-0.5	-0.2	1.5	-1.3	0.2	-0.6	0.3	1.2	0.9	0.1	-0.4	0.0
Average weekly spirits intake	1.2	1.5	7.1	1.0	0.0	1.2	0.3	-1.6	-0.9	-0.2	-2.7	-0.4	-1.3	-0.6	0.4	-0.6	-1.8	-1.8
Sensitivity / hurt feelings	0.7	1.1	4.8	0.7	0.3	1.4	-2.2	1.1	-0.3	-1.0	0.6	-0.1	-1.1	1.2	0.8	0.7	-0.1	-1.7
Frequency of depressed mood in last 2 weeks	0.5	0.7	5.2	-0.1	-0.7	2.3	0.9	0.5	-1.0	-0.2	-0.6	1.1	0.5	-0.4	0.8	0.0	0.5	-0.6
Hearing difficulty/problems: Yes	0.8	1.3	5.6	-0.8	0.2	0.0	1.3	2.4	-0.9	-1.9	1.1	0.5	-0.1	1.5	-0.1	0.8	-0.8	-1.4
Relative age of first facial hair	1.6	3.2	7.9	-0.3	-0.8	-2.3	2.3	-2.4	-0.2	2.6	-2.2	-0.2	-2.0	-2.8	0.2	-1.5	-2.4	0.4
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	7.7	1.7	0.0	-1.0	0.1	2.0	-0.1	-0.5	1.0	-0.2	-0.5	2.8	0.3	0.7	0.1	0.2
Ever used hormone-replacement therapy (HRT)	0.7	0.9	3.3	-1.4	0.8	-0.2	0.7	1.0	0.7	-1.8	0.6	-1.2	0.5	-0.3	0.3	1.5	-0.1	-1.0
Ever had hysterectomy (womb removed)	1.0	1.2	4.3	0.8	-1.8	-2.1	0.5	-0.3	0.4	0.5	-0.7	-1.3	-0.2	-0.2	1.1	-1.3	-1.8	0.4
Systolic blood pressure, automated reading	0.8	2.2	9.9	0.3	0.3	-0.7	1.4	-2.1	2.1	-1.2	-1.1	-3.1	-1.4	-1.9	-0.5	-0.4	-1.4	1.4
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	4.2	0.5	0.8	-1.6	1.5	-0.9	0.3	2.1	-1.7	1.3	-0.0	0.9	-0.2	0.5	-1.7	0.7
Angina	0.9	1.2	3.3	1.2	-1.8	1.1	0.2	0.0	1.1	0.1	0.8	-0.3	1.8	0.1	1.4	-1.4	1.2	1.0
Medication for hormone replacement therapy	1.8	2.1	8.7	-0.5	3.0	-0.9	1.3	-0.7	-0.6	-1.8	0.4	-2.1	-0.3	-0.3	-1.7	2.0	0.1	-1.9
Vitamin and mineral supplements	1.6	2.2	9.2	-0.3	1.5	-0.8	-1.0	-0.3	-0.8	-1.1	2.3	0.2	3.0	0.2	-2.5	1.1	2.3	-0.2
Supplements: Zinc	0.5	0.5	2.1	-0.0	-0.8	0.8	-0.6	1.5	0.2	-0.1	0.0	-0.3	-1.4	-0.5	0.5	-0.1	-1.1	0.6
Medication: Co-codamol	0.8	0.9	2.7	0.4	-0.8	0.7	-0.4	-1.1	-0.7	1.5	-1.1	0.9	1.0	0.5	1.1	-0.8	-0.2	-1.6
Medication: Metformin	0.9	1.3	6.3	1.0	1.2	0.7	-0.0	-0.8	0.7	0.1	-0.3	2.0	0.0	1.8	-1.2	2.5	-0.3	0.1
Diabetes (father)	1.3	1.6	6.6	-0.1	1.2	-0.5	0.6	0.5	-0.6	0.7	-0.8	2.6	-2.2	0.1	-0.2	1.3	-1.1	-2.4
Diabetes (mother)	1.5	1.9	8.9	3.0	1.2	-0.7	0.2	0.1	1.5	0.7	-0.6	-0.8	-1.7	1.5	2.4	-0.7	-1.5	-0.3
Severe depression (siblings)	1.3	1.5	5.9	-0.1	1.4	0.2	0.8	2.2	0.3	-1.7	0.6	2.4	-0.9	0.4	0.4	1.3	-0.3	-1.5
Pack years adult smoking proportion	0.4	0.7	3.3	0.5	1.8	1.2	0.6	0.2	0.4	-1.5	0.1	-0.4	-0.6	0.8	-0.3	0.0	0.8	0.7
Impedance of leg (right)	0.6	2.8	12.2	-3.5	-1.7	0.6	-0.3	-0.0	-1.6	2.7	0.1	-0.0	1.5	-3.3	0.6	-1.0	0.9	-1.3
Leg fat-free mass (left)	0.5	2.8	13.1	3.6	1.0	-1.8	-1.1	0.0	0.5	0.7	-0.9	0.6	-2.9	3.1	1.6	-0.4	-0.7	-0.3
Trunk fat percentage	0.9	3.7	16.3	0.6	-0.5	1.0	-2.0	0.0	-3.4	2.0	-1.2	0.0	-1.9	0.0	2.9	-2.0	-0.7	-4.0
Hand grip strength (right)	0.2	0.6	5.5	0.1	0.8	-2.3	-0.2	-0.6	-0.2	-0.0	-0.0	-0.7	-0.8	-0.4	-0.8	-0.7	0.1	0.3
Townsend deprivation index at recruitment	1.0	1.3	5.7	2.0	-1.0	0.1	-0.8	1.4	0.5	-0.7	1.3	1.3	0.4	2.4	0.2	1.5	-0.1	0.5
Current tobacco smoking	0.4	0.7	2.1	0.8	1.5	-0.1	-0.3	0.8	0.6	-1.3	0.8	-0.6	-1.4	1.2	0.5	-0.3	0.3	0.5
Average weekly fortified wine intake	0.7	0.8	3.2	1.3	-0.6	-0.7	-0.0	0.0	1.1	0.1	-1.8	0.3	-0.7	-0.5	0.7	-0.1	-1.1	1.5
Maternal smoking around birth	1.0	1.4	4.0	-1.1	-1.6	2.0	-0.2	1.6	-0.4	1.1	-0.6	-0.1	-0.6	-1.7	1.4	-0.8	0.8	-1.5
Fed-up feelings	0.5	0.8	2.6	1.6	-0.3	0.8	0.5	1.0	-0.6	-1.1	0.2	-0.5	-1.2	1.3	-0.2	1.5	-0.7	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	2.6	-0.2	-0.8	1.4	-0.2	0.7	-1.2	0.1	0.1	1.1	0.1	0.9	0.5	-0.1	0.1	-1.6
Relative age voice broke	1.3	1.9	6.8	-1.5	1.3	-2.0	1.4	-1.4	-1.1	0.2	-0.6	-1.1	-1.3	-2.6	-2.4	0.6	-0.1	-0.6
Taking other prescription medications	0.5	0.8	4.0	0.1	0.3	-0.5	-1.2	2.0	0.4	-1.4	0.7	0.3	0.1	0.5	0.7	-0.1	-1.2	-0.7
Age when periods started (menarche)	1.4	3.3	9.2	1.2	-1.9	-0.9	1.7	-2.2	0.9	3.0	-2.4	-0.1	-1.6	-0.7	1.5	-2.2	-1.6	2.6
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	2.9	-0.7	-1.7	0.3	0.6	0.5	-1.7	0.0	-0.4	-0.2	1.3	-1.6	-0.8	-0.6	0.1	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	6.2	-0.7	-0.9	2.3	0.0	-0.6	0.0	-0.5	1.4	-0.4	2.5	-0.2	-1.6	1.6	0.7	0.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	2.9	1.0	0.2	-0.1	-1.1	0.5	-0.3	0.5	-0.3	0.3	-1.7	0.6	-0.3	-0.3	-0.5	-0.0
Qualifications: CSEs or equivalent	1.4	1.9	9.9	1.2	1.7	-1.0	-3.1	1.2	0.6	-0.0	2.1	-0.0	-0.7	2.5	0.1	0.4	-0.5	-0.1
Serious illness, injury or assault to yourself	1.7	2.1	6.2	1.9	-1.7	0.7	0.6	-1.9	1.1	2.5	-1.1	-0.9	-1.1	0.5	2.1	-1.5	0.2	1.6
High blood pressure	0.1	0.4	1.5	0.3	-0.8	1.0	1.2	-0.6	-0.4	0.0	0.2	-0.8	0.3	0.4	0.5	-0.1	-0.1	-0.5
Hayfever, allergic rhinitis or eczema	0.5	1.1	6.1	-1.3	-0.3	2.5	0.1	0.0	0.0	-0.7	0.6	-0.5	1.1	-0.8	-1.4	1.1	1.3	-0.7
Multivitamins +/- minerals	0.8	1.0	3.4	0.1	-1.3	0.6	1.3	0.3	0.2	0.7	-1.2	-1.1	-1.8	-0.2	1.6	-1.2	-1.1	-0.0
Stomach or abdominal pain in last month	0.5	0.6	2.7	0.1	0.2	0.4	-1.4	0.2	-0.9	0.2	-0.1	0.6	-1.7	-0.5	0.0	0.4	0.0	-1.5
Supplements: Glucosamine	0.3	0.4	1.4	-0.2	-0.8	1.1	0.2	0.6	0.2	0.7	-0.7	-0.1	0.4	-0.6	1.2	-0.5	0.1	0.8
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	2.7	1.6	1.3	0.0	0.6	-1.4	1.0	0.2	-1.2	-0.9	-1.1	0.6	0.2	0.2	-1.5	1.3
Medication: Atenolol	0.5	0.6	2.5	-0.3	0.9	-1.3	1.4	-1.1	-1.6	-0.2	0.1	-0.0	-0.5	0.2	0.6	-0.3	-0.5	-0.4
Medication: Levothyroxine sodium	0.3	0.6	3.6	0.6	0.0	-0.5	-0.6	-0.2	0.7	0.7	-0.3	1.9	0.2	0.4	1.4	-0.6	-0.5	-0.5
Sitting height	0.2	1.6	5.8	-0.6	-0.8	-2.2	-1.5	-0.2	0.5	1.9	1.1	0.8	1.4	0.1	1.5	-0.7	2.4	-0.4
Chronic bronchitis/emphysema (father)	0.8	0.9	3.8	0.1	-0.2	0.3	1.2	0.7	0.1	-2.0	0.8	-1.2	1.4	0.4	-0.7	1.2	1.0	-0.5
High blood pressure (mother)	0.3	0.5	2.1	0.1	1.2	-0.4	-0.6	0.6	-0.4	-1.0	-0.2	0.5	0.7	0.2	-0.2	0.5	-0.1	-1.5
Body mass index (BMI)	0.7	2.9	8.9	3.0	1.2	0.7	-0.7	-0.5	-1.0	0.3	-1.4	0.1	-2.8	2.5	2.5	-0.9	-1.6	-2.2
Impedance of leg (left)	0.7	3.2	17.5	-4.2	-1.6	0.8	-0.5	0.3	-1.8	2.2	0.4	0.4	1.8	-3.5	0.6	-0.8	0.8	-1.4
Leg predicted mass (left)	0.5	2.8	13.4	3.7	1.0	-1.7	-1.1	-0.0	0.6	0.7	-0.8	0.6	-2.8	3.1	1.6	-0.4	-0.7	-0.1
Trunk fat mass	0.8	3.6	11.3	1.7	-0.3	0.6	-1.9	-0.1	-2.4	2.1	-1.5	0.2	-2.6	1.0	3.4	-1.9	-1.0	-3.3
Waist circumference	0.7	2.6	7.5	2.7	0.5	1.0	-1.1	-0.1	-0.7	0.3	-1.6	-0.4	-2.7	1.8	2.6	-1.2	-1.6	-2.1
Number of incorrect matches in round	0.4	0.6	2.2	0.7	0.3	-0.8	0.4	0.3	1.2	-1.5	0.4	1.3	1.2	0.7	0.4	0.1	-0.8	0.5
Past tobacco smoking	0.7	1.4	7.5	2.7	-0.8	-1.4	0.1	-0.7	1.3	1.7	-0.5	0.1	0.5	1.1	1.2	-1.0	0.2	1.0
Alcohol usually taken with meals	1.1	1.8	6.7	-0.9	-1.6	-1.0	1.7	-0.9	-1.6	1.0	-0.8	-1.9	0.6	-1.9	0.9	-2.6	0.4	0.4
Nervous feelings	0.2	0.4	1.3	1.1	0.0	-0.1	-0.6	0.1	0.5	-0.6	0.7	-0.0	-0.2	0.3	-1.1	0.8	0.3	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.0	0.4	-1.1	0.1	-0.7	1.4	-0.6	0.2	0.3	0.5	-1.1	0.7	-0.6	0.7	-1.4	0.5
Hearing difficulty/problems with background noise	1.0	1.6	7.4	1.1	-0.2	0.7	-1.0	1.9	1.1	-0.3	0.4	2.7	0.0	2.1	1.0	0.7	-1.2	0.6
Hair/balding pattern: Pattern 2	0.6	0.8	3.0	-1.1	1.6	-1.0	0.6	0.2	0.3	-0.8	0.4	0.5	-0.1	0.4	-1.7	1.2	0.2	-1.0
Had menopause	1.0	1.2	3.1	0.5	-0.3	-0.6	1.4	-0.8	0.7	0.9	-1.8	-1.7	0.6	-1.2	1.4	-1.6	-0.7	1.1
Had other major operations	0.5	0.6	1.8	0.1	0.9	-0.6	0.7	0.7	-0.6	0.8	-0.8	1.3	-0.4	0.5	-0.2	1.4	-1.0	-0.5
Forced vital capacity (FVC)	0.4	1.5	6.4	-1.8	-0.4	-2.5	-1.2	0.6	-0.2	0.4	0.1	-0.1	0.0	-2.1	0.6	-1.7	1.6	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	8.2	0.1	0.0	1.9	0.2	-0.8	0.8	-0.6	2.2	-0.8	2.9	0.4	-1.4	1.4	0.9	1.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	2.6	0.1	1.6	1.2	-0.8	1.5	-0.6	0.3	-0.0	1.4	-0.6	0.1	1.5	-0.7	-0.2	-0.4
Qualifications: None of the above	0.6	1.3	4.2	-1.2	0.2	-1.1	0.1	1.7	-0.9	-2.0	1.8	0.8	-0.1	0.9	0.7	0.4	-0.2	-2.0
Financial difficulties in last 2 years	0.7	0.9	5.8	0.8	0.1	0.3	0.3	-0.3	-0.5	0.1	-0.8	1.1	-2.4	1.1	0.3	0.8	-1.7	-0.4
Mouth/teeth dental problems	0.6	0.9	4.5	0.6	-1.1	-0.7	1.0	-0.3	0.6	1.4	-1.1	0.8	-1.0	0.5	-0.4	-0.4	-0.7	2.1
Heart attack	0.7	0.9	3.1	0.8	-0.5	0.2	-0.4	-0.0	-0.6	-0.4	1.5	0.1	-0.0	1.4	1.5	-1.8	1.5	0.1
Allergy	0.4	1.0	5.5	0.5	0.3	-2.4	0.5	0.3	-1.1	1.0	-0.8	-0.2	-2.0	0.6	0.8	-0.5	-0.9	-0.2
Pain all over the body in last month	1.5	1.6	4.8	-0.5	-0.1	1.7	0.3	-2.1	2.2	0.6	-1.7	0.8	-0.7	-1.5	1.5	0.3	-1.1	0.9
Diabetes (self-reported)	0.5	0.8	3.1	1.0	1.3	0.5	-0.5	-0.4	0.8	-1.0	-0.3	1.0	0.4	1.4	-1.2	1.7	-0.4	-0.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	3.1	-0.9	-0.2	1.8	0.7	0.2	1.0	0.1	0.4	0.7	0.7	-0.1	0.4	0.8	-0.3	-1.0
Medication: Ramipril	0.3	0.4	1.5	-0.2	0.3	-0.7	0.3	0.6	-0.7	0.4	0.4	1.2	-0.1	0.7	-0.1	0.7	-0.7	-1.1
Medication: Simvastatin	0.4	0.5	1.6	0.9	0.2	1.2	0.3	-0.8	0.8	-0.8	0.6	0.4	1.1	1.3	-0.6	0.3	0.1	0.4
Fluid intelligence score	0.5	1.0	3.6	-0.8	0.7	-0.1	1.6	0.8	-0.2	-0.8	-0.3	-0.3	1.9	-0.7	-1.1	0.5	1.1	1.6
Illnesses of siblings	0.2	0.2	1.2	0.5	0.0	0.5	-0.7	-0.6	-0.0	0.6	-0.0	-0.3	0.3	0.1	0.2	-1.1	0.2	0.5
Neuroticism score	0.4	0.8	3.2	1.4	0.2	1.1	-0.2	1.8	-0.3	-1.2	0.6	0.1	-1.1	1.4	-0.1	0.9	-0.4	-0.4
Weight	0.5	2.6	8.9	2.6	0.5	-0.4	-1.1	-0.3	-0.6	1.3	-1.4	0.6	-2.7	2.2	3.0	-1.1	-1.2	-1.7
Impedance of arm (right)	0.9	4.1	13.2	-3.4	-1.8	0.7	-1.8	1.8	-3.6	0.7	0.7	0.3	2.1	-3.5	-1.0	-1.1	1.7	-2.0
Arm fat percentage (right)	0.8	3.2	12.6	1.7	0.7	1.4	-2.0	0.2	-2.8	0.6	-1.2	0.3	-2.5	0.9	2.4	-1.3	-1.1	-3.5
Trunk fat-free mass	0.5	3.0	10.9	3.3	1.1	-1.8	-0.1	-0.4	2.1	0.8	-1.0	0.8	-3.0	2.9	1.9	-0.0	-1.3	0.9
Hip circumference	0.4	1.9	6.2	2.3	0.1	0.9	-1.4	0.3	-0.7	1.3	-0.5	0.9	-1.9	2.1	2.5	-0.8	-0.5	-1.5
Time employed in main current job	0.7	0.9	2.4	1.2	-0.4	0.1	-1.5	0.2	0.5	-1.3	1.4	-1.4	0.6	1.3	-0.3	0.4	0.7	-0.6
Alcohol intake versus 10 years previously	0.4	0.7	2.0	-0.7	0.1	-0.8	-1.2	0.8	-0.8	0.5	0.8	0.9	-0.8	1.4	0.2	1.1	0.4	-0.6
Father’s age at death	0.7	1.0	3.7	0.5	-1.3	0.4	-0.0	-0.0	0.2	1.9	-1.1	1.1	-0.5	-1.3	0.8	-1.6	-0.6	0.8
Worrier / anxious feelings	0.4	0.7	2.0	1.4	-0.5	1.4	-0.6	0.4	1.0	0.2	0.7	-0.4	-1.3	0.8	0.5	0.6	-0.8	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	4.3	0.9	-1.3	1.7	-0.5	0.2	-1.1	0.7	0.5	0.8	2.1	-0.1	0.6	-0.3	1.2	0.0
Falls in the last year	0.9	1.3	6.0	1.7	0.6	2.5	0.6	0.5	-0.2	-1.1	-1.3	0.4	-1.0	1.6	1.6	-0.3	0.1	-0.5
Hair/balding pattern: Pattern 3	0.6	0.9	2.8	1.1	-1.0	-0.1	0.2	0.6	1.7	0.6	0.3	0.2	-0.2	1.5	0.4	1.4	-1.3	0.9
Number of live births	0.6	0.9	3.0	0.7	-0.2	0.1	-0.2	-1.2	-0.3	1.7	-1.7	-0.2	-1.1	-0.9	0.9	-0.7	-1.0	-0.6
Forced expiratory volume in 1-second (FEV1)	0.7	2.2	11.7	-2.0	-0.3	-2.1	-0.3	-0.1	-1.2	0.3	0.5	-1.1	0.7	-2.1	0.6	-2.0	3.4	0.3
Pulse rate	0.3	0.6	2.6	1.6	0.6	0.3	-0.3	0.2	0.1	1.0	-1.6	0.7	-0.9	0.2	0.4	-0.3	0.1	-0.5
Happiness	1.6	1.9	5.3	1.9	2.3	-1.1	-1.8	2.0	0.4	-0.6	0.2	1.8	-1.2	1.9	0.4	0.1	-1.4	0.0
Noisy workplace	0.5	0.6	2.4	1.0	0.9	0.2	0.7	-0.1	0.3	0.1	-0.2	-1.5	-0.1	0.6	1.1	0.1	1.3	-1.1
Qualifications: A levels/AS levels or equivalent	0.7	1.4	6.4	2.5	-0.3	-0.6	1.1	-0.6	0.9	-0.0	-0.6	-1.7	-0.7	1.8	0.4	-1.9	-0.3	1.4
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.2	0.6	-1.8	-1.5	-0.3	1.3	0.6	1.0	-1.1	0.7	-0.7	-0.4	1.6	-1.3	-1.7	1.6
Mouth/teeth dental problems: Dentures	0.4	0.7	3.2	0.4	1.1	0.2	-0.2	0.6	0.1	-1.5	0.2	0.2	1.0	0.3	0.5	1.1	-0.4	-1.8
Asthma	0.5	1.0	4.8	-0.2	0.7	0.9	-1.3	0.5	1.1	-2.2	2.1	0.3	0.7	0.4	-0.2	0.3	0.1	0.0
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.1	6.4	0.7	1.1	2.5	-1.4	1.7	0.9	-2.3	1.7	0.5	1.2	2.2	-0.4	0.8	1.5	-0.2
Medication: Cholesterol lowering	0.4	0.6	1.7	1.3	-0.2	1.1	-0.4	0.4	1.0	-0.1	0.6	0.6	0.4	1.3	-0.5	0.4	-0.2	1.3
Depression (self-reported)	1.0	1.3	7.4	0.7	-0.0	-1.1	-0.1	0.6	-1.6	-0.6	-2.7	0.0	-1.5	-1.2	0.1	-0.9	-1.1	-0.8
Medication: Lansoprazole	1.5	1.8	5.6	2.4	-0.4	-1.6	-0.4	0.7	0.8	0.7	-0.9	-0.1	-2.3	1.6	1.7	-0.2	-2.2	0.2
Prospective memory result	0.7	0.9	2.8	1.4	-0.6	0.4	-1.5	0.2	-1.5	0.3	-0.2	0.5	0.3	1.6	0.2	-0.3	0.5	-1.7
Lung cancer (father)	1.0	1.2	5.3	1.1	1.0	1.4	-0.0	-0.7	-0.0	-0.3	0.1	0.2	0.5	2.2	-1.4	2.3	-0.4	-0.8
Illnesses of mother	0.5	0.7	2.6	-1.2	-0.8	0.8	1.1	-0.7	-0.5	-0.5	0.8	0.0	0.7	-0.9	-1.6	0.5	0.4	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	5.6	-0.5	0.9	-1.6	-0.7	1.0	-0.7	-0.0	0.6	-0.5	0.5	-0.5	0.6	-0.6	2.4	0.3
Pulse wave Arterial Stiffness index	1.3	1.5	6.0	0.6	-2.1	-1.2	0.8	-1.1	-0.1	0.0	-0.5	-2.2	-0.2	-0.6	-1.1	-1.2	-0.7	2.5
Impedance of arm (left)	0.8	3.9	15.1	-3.3	-1.5	0.3	-1.3	0.8	-3.4	0.9	0.4	-0.5	2.1	-3.9	-1.0	-1.5	1.9	-1.8
Arm fat mass (right)	0.7	3.0	7.9	2.4	0.7	0.6	-1.6	0.1	-1.9	0.9	-1.2	0.5	-2.8	1.9	2.7	-1.2	-1.1	-2.8
Trunk predicted mass	0.5	3.1	11.5	3.4	1.1	-1.9	-0.1	-0.4	2.1	0.8	-1.0	0.9	-3.1	2.9	1.8	-0.1	-1.3	1.0
Standing height	0.1	1.5	5.5	-0.6	-1.7	-2.2	-1.6	0.5	0.3	2.3	-0.3	1.3	-0.4	-0.6	1.5	-1.0	0.4	0.5
Length of working week for main job	1.4	1.6	5.3	-0.6	-0.7	-0.5	-2.2	2.3	1.1	-1.0	1.8	-0.3	-0.1	-0.3	1.8	-1.4	0.6	1.1
Exposure to tobacco smoke at home	1.3	1.5	5.7	-1.1	0.5	-0.4	-1.3	0.9	-0.2	0.1	-1.1	1.2	-2.4	0.1	1.1	0.2	-2.0	-2.1
Breastfed as a baby	1.7	2.1	8.0	-0.1	-1.6	-0.6	-0.1	-2.1	-0.4	2.3	-2.8	-0.2	-1.0	-1.5	0.8	-2.1	-1.4	-0.5
Tense / ‘highly strung’	1.0	1.6	5.0	1.6	1.9	-0.8	0.4	1.4	0.6	0.5	-0.4	2.2	-2.1	1.1	-0.0	0.7	-1.3	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.5	1.2	-0.4	0.9	-0.7	1.3	-1.2	0.6	-0.4	0.4	-1.6	0.9	0.2	-0.7	-0.2	0.1
Hair/balding pattern: Pattern 4	0.7	1.6	8.7	-0.6	-1.2	1.2	-0.5	-0.3	-1.2	0.5	-1.4	-1.6	0.4	-2.1	1.0	-2.9	0.7	0.4
Birth weight of first child	0.9	1.6	3.8	1.4	1.4	-1.9	0.3	-0.9	1.7	0.1	-0.3	1.3	-0.8	1.6	-1.4	1.8	-1.8	0.2
Peak expiratory flow (PEF)	1.2	2.7	15.3	-2.3	-0.1	-0.1	-0.1	-0.3	-0.7	-1.1	2.3	-1.2	2.9	-1.2	-1.1	-0.3	3.9	-0.2
Pulse wave reflection index	1.1	1.4	3.9	0.9	-1.8	0.0	0.8	-1.6	-0.6	0.5	-2.0	-1.5	0.1	-1.1	-0.1	-1.8	-0.1	1.6
Ever highly irritable/argumentative for 2 days	0.9	1.1	4.5	1.1	-0.7	1.3	-0.9	1.4	0.6	1.4	0.4	2.1	0.2	0.8	1.5	-0.5	-0.4	0.6
Loud music exposure frequency	1.6	1.8	4.5	-0.2	1.9	-1.0	-1.4	1.4	1.9	0.1	1.4	2.1	-1.6	1.2	-1.0	1.1	-0.6	1.2
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	3.2	1.6	-0.6	0.2	0.4	-0.7	0.9	1.0	-0.8	-1.1	-1.4	0.4	0.8	-0.9	-0.0	1.8
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	4.9	-0.3	-0.5	0.0	-1.3	0.5	-2.2	1.0	0.3	1.6	-0.9	0.5	1.1	-1.1	-0.3	-2.2
Blood clot in the leg (DVT)	0.4	0.5	2.3	-0.2	-0.3	0.4	0.5	-1.0	0.1	-1.2	0.5	-1.1	1.5	-0.1	0.5	-0.8	0.5	0.3
Medication: Paracetamol	0.6	1.0	4.4	-1.2	-1.5	0.4	0.0	1.2	-1.4	0.1	0.8	0.8	-0.0	-0.8	0.3	0.3	0.6	-2.1
Headache pain in last month	0.8	1.4	4.3	0.4	-0.1	-0.9	-1.5	2.1	-0.9	0.6	0.8	2.1	-0.8	0.8	1.2	0.1	0.1	-2.0
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.8	-1.3	0.3	-0.9	1.2	0.1	-0.5	0.2	-0.1	-0.3	0.3	-1.2	-0.8	-0.0	0.5	0.1
Glaucoma (self-reported)	0.4	0.5	3.6	1.9	-0.5	0.4	0.5	0.4	-0.4	-1.1	-0.6	0.9	-0.4	0.5	-0.0	-0.0	-0.3	-0.0
Gout (self-reported)	0.5	0.7	3.0	-0.3	0.9	-0.1	-0.9	0.3	1.0	-0.4	-0.7	0.4	-1.5	0.6	1.7	0.3	-0.3	-0.5
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	4.5	1.4	0.1	-0.3	-0.5	0.5	0.8	0.3	0.6	1.4	-0.4	2.1	1.1	0.4	-0.7	-0.0
Medication: Amlodipine	0.9	1.3	4.8	1.8	1.8	0.6	1.7	-0.2	0.2	-1.3	-0.1	-2.2	0.7	0.5	-0.8	0.2	0.9	0.6
Medication: Ventolin 100micrograms inhaler	1.1	1.5	6.3	-1.1	-0.4	2.2	-2.5	0.7	0.4	-0.2	1.0	1.7	1.9	-0.6	-0.5	-0.5	0.2	-0.7
Birth weight	0.6	1.2	3.5	1.7	0.6	-0.2	-0.9	0.1	-0.8	0.7	-1.9	0.0	-1.3	1.2	1.6	-0.9	-1.5	-0.7
Chronic bronchitis/emphysema (mother)	1.1	1.3	5.8	-0.2	0.4	-0.7	-1.0	0.8	-1.0	2.4	0.6	0.9	-2.0	0.9	1.8	-0.8	-0.7	-0.3
High blood pressure (siblings)	0.3	0.4	1.2	0.6	0.5	-0.1	0.7	-0.5	0.9	-0.5	-0.9	-1.1	-0.7	0.4	0.7	-0.3	-0.8	-0.0
Forced vital capacity (FVC), Best measure	0.2	0.7	2.7	-0.3	0.7	-1.6	-1.3	1.5	0.4	-0.5	0.5	0.2	0.3	-0.2	0.2	0.1	0.9	1.0
Body fat percentage	1.0	3.8	15.3	1.0	-0.3	1.1	-1.4	-0.3	-3.3	2.0	-1.6	-0.1	-2.4	0.1	3.1	-2.0	-1.2	-3.9
Leg fat percentage (right)	1.0	3.4	12.4	1.8	0.3	1.1	-0.5	-0.4	-2.1	1.5	-1.8	-0.1	-3.0	1.0	3.1	-1.1	-1.8	-3.5
Arm fat-free mass (right)	0.5	2.5	8.0	2.8	0.6	-1.9	-0.1	-1.0	1.6	1.5	-0.7	0.7	-2.3	2.7	2.3	-0.6	-0.9	0.4
Exposure to tobacco smoke outside home	0.6	0.8	2.4	1.1	0.5	1.4	0.5	0.4	-0.6	0.6	-1.1	-0.0	-0.4	1.6	1.4	-0.6	0.5	-0.7
Comparative body size at age 10	0.3	0.9	3.0	0.6	1.0	1.7	-0.5	-0.3	0.7	-0.9	-1.1	-0.9	-1.3	0.4	0.6	0.8	-1.5	1.1
Number of full brothers	0.5	0.6	3.7	-1.1	0.6	-0.2	0.5	-0.3	0.1	0.2	-0.5	0.3	-1.9	-0.2	1.4	0.3	-0.7	-0.8
Worry too long after embarrassment	0.8	1.4	7.0	1.4	-0.8	1.2	-2.6	0.8	0.3	0.4	0.2	0.2	-1.2	1.1	2.1	-1.2	-0.5	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	9.5	-0.4	0.8	-0.8	-0.7	1.3	0.1	0.5	-0.6	1.9	-3.1	-0.5	0.6	-0.8	-1.7	0.5
Wheeze or whistling in the chest in last year	0.5	0.8	3.1	1.0	0.7	1.5	0.3	1.2	-0.7	-1.8	0.5	0.0	-0.4	1.0	-0.7	0.5	-0.4	-1.3
Number of children fathered	1.5	1.7	6.5	-2.5	-1.2	1.2	0.2	1.3	-1.5	-0.4	1.2	0.3	1.5	-1.8	0.3	0.3	1.7	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	3.8	0.4	0.2	-0.5	-1.0	-1.0	0.7	-0.4	0.4	-2.0	-0.6	0.1	0.1	-0.5	-0.4	0.0
Age at first live birth	0.5	0.9	6.8	1.4	-0.2	-0.0	0.9	-0.6	0.1	1.5	-2.6	0.4	-0.3	-0.1	-0.3	-0.4	0.4	0.8
Pulse wave peak to peak time	1.3	1.6	5.7	-0.8	2.2	1.0	-0.8	1.1	0.3	0.0	0.4	2.3	0.2	0.5	1.1	1.3	0.8	-2.4
Health satisfaction	0.2	0.3	1.5	1.1	0.4	0.3	0.2	-0.5	0.0	-0.1	-0.4	0.3	-0.8	1.2	0.7	-0.1	-0.3	-0.2
Shortness of breath walking on level ground	1.0	1.2	7.6	0.2	-1.7	0.4	-0.4	-0.1	-0.9	-0.2	-0.0	1.2	-2.8	0.8	0.6	-0.1	-1.8	-1.0
Qualifications: College or University degree	0.4	1.2	4.0	0.5	0.3	0.6	0.8	-0.0	0.1	-0.4	-0.8	-1.8	1.2	-0.8	-0.3	-1.9	1.6	2.0
Eye problems/disorders: None of the above	0.7	0.8	2.4	-1.5	-0.9	0.6	-0.5	-0.0	0.4	0.2	-0.1	0.5	-1.3	-1.4	-0.3	1.5	-1.2	0.1
Mouth/teeth dental problems: Loose teeth	1.2	1.4	5.0	0.3	1.7	-0.5	0.7	0.1	2.2	-1.4	0.9	-1.3	-0.3	-0.1	-1.2	1.2	0.7	2.1
Emphysema/chronic bronchitis	1.1	1.2	3.1	0.1	-1.6	-0.3	-0.9	0.8	-0.3	1.2	1.0	0.9	1.8	0.5	1.4	-1.5	1.8	-0.5
Medication for pain relief, constipation, heartburn	0.7	1.2	7.1	0.9	1.5	-2.7	1.1	-1.2	0.3	0.1	-0.8	-0.7	-0.8	0.8	-0.8	0.1	-0.7	1.3
Neck or shoulder pain in last month	1.0	1.4	6.2	0.3	-0.8	1.2	-0.9	2.5	-0.6	-1.1	1.7	0.8	-0.0	1.5	1.3	-0.2	0.7	-1.8
Medication: Blood pressure	0.2	0.4	1.0	1.0	-0.2	0.6	-0.1	-0.6	-1.0	0.6	-0.3	0.2	-0.3	0.9	0.7	0.1	0.0	-0.9
Angina (self-reported)	1.0	1.4	3.1	1.5	-1.8	1.2	0.0	0.2	1.6	0.1	0.7	-0.1	1.7	0.4	1.6	-1.4	0.9	1.3
Migraine (self-reported)	0.2	0.2	0.7	0.3	-0.2	0.3	-0.1	-0.1	-0.1	0.6	0.2	0.4	-0.8	0.2	0.6	0.4	-0.2	-0.7
Medication: Ibuprofen	1.6	1.9	5.7	0.6	0.8	2.0	-0.8	2.0	1.2	-1.9	1.5	0.9	0.9	2.4	0.0	1.6	1.2	-0.7
Medication: Allopurinol	0.7	0.9	4.3	-0.6	1.4	0.3	0.7	-0.4	0.6	-0.5	-1.4	1.5	-2.1	0.3	0.6	0.9	-1.0	-0.1
Medication: Omeprazole	0.7	0.8	2.7	-0.8	-0.7	0.9	0.0	-0.4	1.2	-1.6	0.2	-1.4	1.3	-1.1	-0.6	0.3	-0.0	0.1
Medication: Seretide 50 evohaler	0.8	0.9	2.7	-1.1	-0.7	1.4	-0.1	-0.7	-0.9	0.5	0.2	0.7	1.4	-1.0	0.2	-1.3	1.6	0.6
Mean time to correctly identify matches	0.5	0.9	3.5	1.9	-1.1	0.1	-0.7	-0.6	1.5	0.1	-0.1	0.6	-0.4	0.9	0.8	-0.6	-1.1	1.5
Heart disease (mother)	0.6	0.7	2.3	0.9	-0.7	-0.8	-1.2	1.5	0.1	0.6	-0.1	-0.7	-1.1	-0.3	1.0	-1.4	0.1	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.7	-0.3	-0.7	0.3	-0.1	0.2	0.9	-0.4	-0.7	0.2	-0.9	-0.6	-0.7	0.5	-0.8	1.6
Whole body fat mass	0.8	3.3	10.4	1.7	0.1	0.4	-1.5	-0.2	-2.2	1.9	-1.5	0.2	-2.7	1.1	3.2	-1.7	-1.1	-3.2
Leg fat mass (right)	1.0	3.8	12.0	2.5	0.5	0.0	-1.0	-0.3	-1.6	1.6	-2.0	0.2	-3.5	1.9	3.4	-1.4	-1.6	-2.7
Arm predicted mass (right)	0.5	2.6	8.1	2.8	0.5	-1.8	-0.3	-0.9	1.7	1.5	-0.8	0.5	-2.4	2.6	2.4	-0.8	-1.0	0.3
Pulse rate, automated reading	0.3	0.9	2.8	1.2	1.1	-1.4	-0.5	-0.2	0.5	0.9	-0.8	-1.1	-1.7	0.2	0.2	-0.4	-1.2	-1.0
Alcohol intake frequency.	0.8	1.8	7.9	-0.1	-0.1	-1.0	-2.6	1.8	-0.9	0.6	1.8	2.8	0.1	0.8	0.3	1.2	0.0	-1.0
Comparative height size at age 10	0.1	0.6	2.0	-0.6	-0.9	-0.6	-1.3	0.9	-0.1	0.8	0.2	-0.2	0.3	-0.4	1.0	-1.4	-0.0	0.8
Number of full sisters	1.0	1.3	3.7	0.1	0.5	-1.9	-0.8	0.8	-0.9	1.4	0.2	0.1	-0.6	0.6	1.9	-1.8	-0.0	-1.9
Suffer from ‘nerves’	0.6	0.9	4.3	-0.6	1.3	0.1	-0.2	0.4	-2.0	-0.5	0.6	-1.0	-0.7	0.5	-0.4	0.4	0.2	-2.1
Overall health rating	0.4	0.8	3.8	-0.1	0.0	-0.6	0.1	1.0	-1.5	-1.2	0.8	-0.3	0.1	0.9	0.2	1.1	0.9	-2.0
Chest pain or discomfort	0.7	1.0	7.0	-0.1	0.8	2.6	-0.2	-1.1	-1.0	-1.0	-0.3	-0.3	0.3	-0.7	0.4	0.3	1.5	-1.0
Had major operations	0.5	0.6	2.1	0.1	-0.8	1.4	0.3	0.7	0.6	-0.4	-0.1	-0.2	-0.2	-0.4	1.4	-1.4	-0.2	0.7
Age at last live birth	1.7	2.5	16.6	1.0	0.3	0.9	1.3	-1.8	-1.0	2.5	-4.1	1.2	-0.4	-1.6	-0.7	-0.4	-1.1	0.6
Family relationship satisfaction	2.8	3.4	14.1	1.9	2.0	-2.6	-0.5	1.9	1.0	0.7	-0.7	1.3	-3.8	1.4	1.8	-0.9	-3.0	0.7
Leg pain on walking	0.9	1.1	4.7	1.2	-1.0	0.2	-0.5	0.6	0.6	0.7	0.5	2.2	-1.2	1.9	1.2	1.0	-0.2	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	5.7	0.2	0.3	0.2	-0.0	-2.4	0.7	2.0	-1.9	0.5	-0.8	-0.3	2.1	-0.8	-1.1	0.0
Commuting to job workplace: Car/motor vehicle	1.4	1.6	4.1	-1.9	-0.2	-1.8	0.0	-0.2	-0.2	0.9	-1.3	-0.6	-2.0	-1.7	1.5	-1.0	-2.0	-0.6
Illness, injury, bereavement, stress in last 2 years	1.1	1.4	4.1	-1.9	1.6	1.2	0.4	0.3	-0.7	-1.3	0.5	0.8	1.7	-0.6	-2.0	1.2	0.7	-0.4
Medication: Aspirin	0.4	0.5	1.4	-0.4	-1.1	1.2	0.5	1.0	-0.3	0.8	0.0	0.7	0.9	-0.2	0.7	0.2	0.4	-0.9
Supplements: Vitamin C	1.1	1.3	4.7	1.2	-1.2	0.4	-0.3	0.9	0.9	0.2	-0.7	1.6	-2.2	0.2	1.7	-0.3	-1.9	1.1
Knee pain experienced in last month	1.4	2.2	5.3	1.5	0.7	0.4	-1.7	0.3	2.3	-0.9	-0.6	1.5	-2.3	2.1	1.0	1.8	-1.4	1.6
Hypertension (Self-reported)	0.1	0.4	1.7	0.3	-0.3	1.0	1.3	-0.3	-0.5	-0.3	0.6	-1.0	0.4	0.9	0.3	0.1	0.3	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	3.7	0.5	-1.8	-0.3	-1.4	-0.7	0.5	0.0	-1.8	0.1	-0.4	-0.9	0.9	-0.4	-1.9	-0.2
Illnesses of father: Heart disease	1.0	1.4	6.6	-2.3	-0.4	-0.6	-0.3	1.3	-1.3	-1.3	1.1	-0.9	0.2	0.2	0.9	0.2	0.7	-2.6
Illnesses of siblings: Diabetes	0.6	0.7	2.9	0.5	-0.7	0.3	1.0	-0.0	-0.3	1.7	-1.4	0.8	-0.0	1.2	0.9	0.4	0.0	-0.8
Smoking status: Previous	0.9	1.3	8.4	-2.9	0.5	0.7	0.2	-0.4	-1.4	-1.3	0.0	-0.2	-0.3	-1.9	-1.4	0.5	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.7	-0.8	1.3	0.3	0.1	-0.3	0.3	0.4	-0.1	0.8	0.7	-0.4	-0.3	0.6	1.3	0.3
Whole body fat-free mass	0.5	3.0	11.8	3.4	1.0	-1.9	-0.5	-0.3	1.5	0.8	-0.9	0.8	-3.0	3.1	1.9	-0.2	-1.1	0.5
Leg fat-free mass (right)	0.5	2.5	11.3	3.4	1.1	-1.7	-1.2	0.1	0.6	0.3	-0.8	0.9	-2.6	3.0	1.4	-0.2	-0.7	-0.1
Arm fat percentage (left)	0.8	3.1	11.8	1.8	0.7	1.2	-1.8	-0.1	-2.7	0.8	-1.2	-0.1	-2.5	0.8	2.5	-1.6	-0.9	-3.4
Average weekly red wine intake	1.2	1.8	5.8	-0.1	-1.5	0.8	1.6	-2.4	-0.1	0.4	-1.4	-1.7	-1.0	-2.0	0.8	-2.0	-0.7	0.6
Handedness (chirality/laterality): Left-handed	1.8	2.2	6.0	0.1	1.8	-1.5	0.2	-2.5	-0.2	2.2	-0.9	-0.3	-2.3	0.3	1.7	-1.5	-2.1	0.8
Mood swings	1.0	1.7	6.4	0.5	0.5	2.1	-0.1	1.8	0.4	-1.4	1.8	1.1	0.6	1.6	-1.2	2.5	0.2	-0.3
Loneliness, isolation	0.9	1.2	5.0	-0.1	1.4	-0.3	-0.1	2.2	-0.5	-1.7	2.1	0.2	0.2	1.3	-0.7	0.7	0.4	-0.9
Long-standing illness, disability or infirmity	1.0	1.5	4.9	1.2	0.2	0.2	0.5	1.1	-0.4	-1.4	1.4	0.5	0.6	2.2	-1.4	2.2	1.4	-1.4
Ever had bowel cancer screening	2.2	2.6	6.3	-0.3	-2.5	-0.3	1.2	-1.8	2.4	1.2	-1.2	-1.9	-1.3	-1.5	2.0	0.2	-2.1	1.7
Diabetes diagnosed by doctor	0.6	1.0	3.6	0.9	1.6	0.5	-0.4	-0.2	0.1	-1.1	-0.3	1.1	0.1	1.5	-1.2	1.9	-0.6	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	4.4	0.8	-0.2	-0.9	-0.4	0.4	-1.7	2.1	-1.1	0.6	-1.5	0.9	1.2	-1.2	-0.5	-1.1
Friendships satisfaction	0.8	1.0	3.4	0.6	0.8	-0.4	-0.9	1.1	1.8	1.0	0.7	0.4	-0.8	-0.2	1.8	-1.2	-0.1	1.3
Qualifications: nursing, teaching	1.3	2.1	12.6	3.6	1.1	1.9	0.8	-1.7	0.7	0.8	-2.0	0.3	-0.3	1.8	-0.2	-0.3	-1.0	0.9
Commuting to job workplace: Walk	0.9	1.0	5.5	1.5	1.2	0.4	1.2	-0.3	-0.5	-1.1	-0.1	0.1	1.0	0.9	-2.4	0.9	0.3	0.2
Eye problems/disorders: Cataract	0.8	0.9	3.5	-0.8	-0.8	-0.2	-0.3	0.9	0.7	0.4	1.6	-1.9	0.4	-1.3	0.3	-1.5	0.6	0.4
Mouth/teeth dental problems: Mouth ulcers	1.2	1.8	5.6	-1.7	-0.8	1.9	-1.1	-1.0	-0.5	-0.7	0.6	-2.0	1.9	-2.4	-0.2	-0.3	1.8	-0.5
Medication for cholesterol	0.6	0.9	6.5	-0.8	-0.6	0.1	-1.2	1.4	-1.3	0.5	0.1	2.5	0.3	-0.0	0.1	-0.6	0.4	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.0	-0.1	-0.6	0.1	-1.3	0.3	1.4	1.2	-0.0	0.2	0.3	-1.4	1.2	0.4	-0.6	1.3
Back pain experienced in last month	0.7	1.0	3.8	0.6	-0.3	1.9	-0.8	1.4	-0.8	-0.4	0.4	1.5	0.5	1.7	0.1	0.6	0.6	-0.8
Mineral and other dietary supplements	0.7	1.0	5.1	0.8	2.3	0.0	0.5	-0.1	-0.3	-1.2	0.9	0.8	0.3	1.6	-0.9	1.2	0.9	-0.4
Breast cancer (self-reported)	0.9	1.0	4.3	0.4	-0.6	-0.1	-1.0	0.9	-2.1	-0.0	-1.2	1.5	0.4	0.8	-1.8	0.7	-0.4	0.6
Asthma (self-reported)	0.6	1.1	5.3	-0.0	1.0	0.6	-1.3	0.5	1.5	-2.3	2.0	0.6	0.7	0.5	-0.2	0.4	0.1	0.2
Osteoporosis (self-reported)	0.6	0.8	6.0	-0.3	-0.4	0.1	0.3	0.8	-1.1	-0.9	-0.2	-2.4	0.5	-0.5	0.1	-1.1	0.3	-0.8
Osteoarthritis (self-reported)	0.8	1.0	5.0	-0.8	-1.5	0.1	-0.9	1.9	-0.6	0.2	0.5	0.4	-0.9	0.4	1.0	0.6	0.0	-2.2
Medication: Aspirin	0.3	0.4	2.0	0.0	-0.4	1.4	0.3	1.3	0.0	0.1	0.2	0.0	0.9	0.3	0.6	0.4	0.2	-0.5
Medication: Gliclazide	0.5	0.6	3.1	0.2	-0.7	0.5	0.1	-0.7	-0.1	0.7	0.7	0.1	1.8	1.5	-0.1	0.9	0.2	0.2
Illnesses of father: None of the above (group 1)	0.3	0.4	1.2	0.1	0.3	-0.3	-0.3	-0.9	0.9	0.2	-0.3	0.9	0.1	0.3	-0.5	0.5	-1.1	1.0
Smoking status: Current	0.4	0.6	1.6	0.6	1.2	-0.0	-0.6	1.1	0.4	-1.1	1.1	-0.7	-1.0	1.3	0.5	-0.2	0.6	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	8.8	0.3	1.1	-1.7	1.0	0.5	-1.4	0.1	-0.3	-1.6	0.2	-0.1	0.9	-0.8	3.0	-1.1
Whole body water mass	0.5	2.8	11.0	3.3	0.9	-1.8	-0.5	-0.4	1.6	0.8	-0.9	0.8	-2.9	3.0	1.9	-0.2	-1.1	0.5
Leg predicted mass (right)	0.5	2.5	11.1	3.3	1.1	-1.8	-1.2	0.1	0.6	0.3	-0.8	1.1	-2.7	3.0	1.5	-0.2	-0.8	-0.1
Arm fat mass (left)	0.8	3.2	9.1	2.5	0.9	0.2	-1.6	-0.2	-1.7	1.2	-1.3	0.6	-3.0	1.8	2.9	-1.4	-1.3	-2.8
Number of self-reported non-cancer illnesses	0.3	0.5	1.8	1.0	-0.8	-0.7	-0.4	0.1	1.0	-0.5	0.0	0.1	-0.3	1.0	0.6	0.2	-1.3	-0.2
Average weekly champagne plus white wine intake	0.8	1.1	5.1	0.1	-0.4	-0.1	0.1	-2.3	-0.2	1.5	-1.4	-0.1	0.5	-0.5	1.7	-2.0	-0.3	-0.2
Miserableness	0.8	1.4	7.0	-0.0	0.6	1.9	-0.9	2.6	-1.2	-0.5	0.2	1.6	-1.0	0.7	0.6	1.2	0.1	-1.3
Guilty feelings	0.2	0.4	0.8	-0.8	0.4	0.8	0.0	0.9	-0.7	-0.4	0.6	0.4	-0.2	-0.1	-0.7	0.7	-0.8	-0.5
Wears glasses or contact lenses	1.2	1.4	6.2	-0.3	-2.0	0.6	0.4	-0.6	0.1	0.8	-1.5	-0.9	-0.1	-1.9	1.1	-2.5	-0.7	0.8
Ever taken oral contraceptive pill	0.5	0.5	1.6	1.1	-0.0	1.3	-1.3	0.8	1.0	0.3	-0.2	0.8	0.4	0.5	0.7	0.1	0.1	0.4
Hearing aid user	0.6	0.7	3.4	1.4	1.9	-0.2	0.6	0.2	0.8	-0.9	-0.4	0.5	0.4	1.4	0.5	-0.7	-0.3	-0.1
Mother’s age at death	0.8	1.0	4.3	0.4	-1.2	-0.6	-0.3	-0.3	2.1	0.4	0.2	1.2	0.6	0.3	-1.1	2.0	-0.3	1.1
Financial situation satisfaction	1.1	1.4	3.3	1.8	1.2	-1.0	-0.9	0.9	-0.5	-0.6	0.5	-0.4	-1.4	1.8	1.5	-1.7	-1.2	-0.6
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.8	-0.2	-0.5	-0.1	0.1	0.7	-0.6	-0.9	0.7	-1.3	0.5	-0.0	-0.2	-0.1	-0.3	-0.3
Commuting to job workplace: Public transport	1.0	1.1	4.3	0.1	-0.4	1.8	-1.1	1.0	-0.4	-0.9	1.0	2.1	0.3	0.4	-1.4	1.5	-0.2	-0.6
Eye problems/disorders: Glaucoma	0.6	0.7	4.1	2.0	-0.2	1.1	0.2	-0.1	-0.0	-0.8	-0.0	0.8	0.3	0.8	0.6	-1.1	1.3	-0.2
Medication: Blood pressure	0.6	1.1	3.3	0.5	-1.3	1.2	0.0	-0.2	1.8	-0.9	1.8	-1.4	1.4	0.6	-0.1	0.6	0.3	0.8
Pain type(s) experienced in last month: Hip pain	1.6	2.1	8.1	-0.7	-0.6	-0.5	-1.7	1.0	-2.1	-0.3	1.7	0.9	1.2	0.7	1.1	-1.2	2.3	-2.8
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.0	-0.4	-1.3	-1.4	-0.6	0.1	0.7	0.8	-0.3	-1.4	-1.0	-1.3	0.2	-1.1	-0.8	0.4
High cholesterol (Self-reported)	0.5	1.0	4.2	0.5	1.0	-0.5	-0.7	-1.1	1.5	-2.0	0.9	-1.5	-0.6	0.8	0.5	-0.1	-0.6	0.3
Medication: Bendroflumethiazide	0.8	1.3	6.3	-0.1	-1.4	2.1	1.2	-1.1	-0.2	0.5	1.4	-0.1	2.5	0.3	-0.8	0.3	0.6	-0.0
Medication: Paracetamol	0.5	0.8	3.8	-0.8	-1.2	0.4	-0.2	0.9	-1.2	0.3	0.4	1.3	-0.5	-0.3	0.7	0.3	0.3	-1.9
Medication: Lisinopril	1.2	1.5	5.4	2.3	1.8	-0.2	0.9	-1.8	1.6	0.2	-0.9	-2.2	0.1	1.0	0.5	-0.3	0.4	-0.1
Medication: Atorvastatin	0.9	1.1	7.8	0.6	1.5	-1.8	0.4	0.7	0.3	-1.3	0.9	-2.8	-0.0	0.3	-0.2	-0.1	0.0	-0.1
Illnesses of father: High blood pressure	0.3	0.3	1.9	0.1	-0.5	0.3	-0.8	0.7	0.1	-0.3	-0.1	0.5	-1.4	0.5	0.4	0.0	-0.9	-0.0
Alcohol drinker status: Never	0.6	0.8	4.7	-0.8	0.6	-1.8	0.4	0.0	-0.4	0.2	0.2	2.2	0.6	-0.0	-0.6	0.9	0.3	-0.4
Ever smoked	0.8	1.4	3.9	-2.0	1.2	1.1	-0.3	0.9	-0.8	-1.5	-0.4	1.0	-1.8	-0.4	-1.1	1.3	-1.7	-0.7
Basal metabolic rate	0.5	2.9	11.2	3.3	1.1	-1.6	-0.7	-0.2	1.0	1.0	-1.0	1.0	-2.9	3.0	2.2	-0.3	-1.0	-0.1
Leg fat percentage (left)	0.9	3.4	13.0	1.5	0.5	1.3	-0.6	-0.2	-2.1	1.0	-1.7	0.0	-3.0	1.1	3.2	-1.0	-2.0	-3.6
Arm fat-free mass (left)	0.5	2.5	8.8	2.7	0.8	-1.3	-0.3	-0.4	1.8	0.8	-0.4	0.9	-2.4	3.0	2.5	-0.4	-1.0	0.4
Number of operations (self-reported)	0.3	0.5	2.8	0.4	0.2	-0.1	0.9	-0.7	-0.0	1.0	-1.7	0.7	0.7	-0.2	0.2	-0.2	-0.6	0.7
Average weekly beer plus cider intake	0.6	0.9	2.9	0.4	1.7	-0.8	1.1	1.2	0.2	-0.9	-0.5	-0.6	-1.1	1.0	-0.7	1.2	-1.1	0.4
Irritability	0.9	1.5	4.6	0.1	0.8	1.5	0.2	2.1	0.5	-1.5	1.5	-0.3	0.4	0.5	-1.8	2.1	0.8	1.0
Risk taking	1.3	1.8	6.8	1.2	2.6	0.1	0.1	0.5	1.1	-1.3	-0.6	0.2	-2.6	1.8	-0.0	1.5	-1.4	-1.3
Ever had prostate specific antigen (PSA) test	1.0	1.1	6.4	-0.7	0.5	-0.2	1.5	-0.3	0.2	-0.7	-1.4	0.3	-1.8	-1.2	0.3	0.0	-2.5	0.1
Fractured/broken bones in last 5 years	0.7	0.9	2.9	0.9	-0.3	1.2	-0.5	-1.7	0.4	0.7	-1.5	-0.5	-1.3	0.2	1.0	-1.4	-1.0	-0.0
Age started oral contraceptive pill	1.4	1.8	4.6	-1.7	-1.7	0.2	0.7	-1.6	-0.8	1.6	-1.5	-1.4	0.3	-2.2	0.8	-2.1	-0.0	0.1
Diastolic blood pressure, automated reading	0.7	2.1	6.8	1.2	0.5	1.3	0.7	-2.1	1.9	-1.1	-1.4	-2.6	-1.8	-1.5	-0.6	-0.2	-1.5	1.3
Ever depressed for a whole week	0.7	0.9	3.1	0.9	0.6	1.5	-1.8	1.2	-0.0	0.1	0.8	1.3	0.1	0.2	1.3	-1.0	-0.1	-0.3
Unable to work because of sickness or disability	0.9	1.2	3.8	1.4	-0.2	-1.2	0.5	0.3	-0.7	1.5	-1.0	0.8	-1.4	1.7	1.9	-1.1	-0.3	0.3
Commuting to job workplace: Cycle	0.5	0.6	2.2	-0.1	0.8	-1.5	-1.3	-0.1	0.0	-0.2	0.2	1.5	-0.3	-0.1	-0.8	1.2	-0.7	-0.1
Myopia	0.9	1.4	5.8	1.4	-0.8	-1.0	1.8	-0.6	-0.6	0.4	-2.4	-0.8	-1.0	-0.5	0.1	-0.9	-1.2	1.6
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.3	-0.8	1.5	-1.2	-0.9	0.6	0.2	-0.2	-0.4	0.9	-0.7	-0.8	-0.8	0.4	-0.4	0.5
Cholesterol lowering medication	0.6	0.9	2.4	1.6	0.8	-1.2	1.4	-1.2	1.0	-0.9	-0.4	-1.3	-0.2	0.9	0.8	-0.6	-0.1	0.2
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.1	-0.5	-0.9	1.1	0.4	-0.2	1.2	-1.5	0.6	-1.5	1.8	-0.9	-0.6	0.7	0.7	0.2
Pain experienced in last month	0.8	1.3	6.1	-0.4	1.3	-1.1	1.1	-1.9	0.1	-0.1	0.6	-2.5	1.0	-0.6	-1.8	-0.1	0.1	1.0
Supplements: Calcium	1.1	1.3	4.6	-0.2	-2.1	1.3	0.8	1.2	0.1	-0.1	-0.1	-1.0	-0.1	0.5	2.0	-1.7	-1.1	1.0
Basal cell carcinoma (self-reported)	1.0	1.2	4.0	-1.9	-0.3	-1.2	0.8	1.3	-1.5	-0.6	0.1	0.4	2.0	-1.7	-0.3	-0.5	-0.0	0.3
Heart attack/myocardial infarction (self-reported)	0.7	0.9	3.3	0.9	-0.6	0.3	-0.1	-0.2	-0.7	-0.4	1.3	-0.1	-0.1	1.2	1.3	-1.8	1.7	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	3.0	-0.0	-0.1	0.5	0.5	-1.1	0.1	-1.5	0.6	-1.3	1.7	-0.4	0.5	-0.7	0.9	0.1
Heart disease (siblings)	1.7	2.1	7.6	-2.8	-0.5	-1.4	-1.0	0.4	-0.4	-0.9	1.3	2.6	0.1	-1.8	-1.9	2.0	0.0	-0.3
Alcohol drinker status: Previous	0.5	0.6	2.2	0.7	1.3	-1.2	0.0	0.5	-0.2	-0.4	0.3	0.4	0.8	1.2	0.3	0.4	-0.3	-1.5
Pack years of smoking	0.5	0.7	2.8	0.6	1.7	1.1	0.9	-0.1	0.5	-1.5	-0.0	-0.7	-0.7	0.8	-0.5	0.5	0.6	0.9
Impedance of whole body	0.8	4.2	16.7	-4.1	-2.0	1.0	-1.0	0.5	-2.8	1.7	0.4	-0.1	2.4	-4.1	-0.1	-1.3	1.5	-1.8
Leg fat mass (left)	0.9	3.7	12.3	2.4	0.5	0.1	-1.1	-0.2	-1.7	1.4	-1.8	0.3	-3.3	2.0	3.5	-1.4	-1.6	-2.8
Arm predicted mass (left)	0.5	2.4	8.9	2.7	0.8	-1.4	-0.3	-0.6	1.8	0.9	-0.3	1.0	-2.2	3.0	2.3	-0.2	-1.1	0.2