Hub : Genes

EMB

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2590 0.0640 0.0e+00 0.269 0.293 0.279 0.29 0.273 1.1e-32 5.5e-36 4.3e-34 1.4e-35 2.8e-33
2 GTEx Adipose Subcutaneous 0.0500 0.0250 4.4e-04 0.055 NA 0.029 NA 0.045 2.8e-05 NA 1.9e-03 NA 1.3e-04
3 GTEx Adrenal Gland 0.2439 0.0930 2.5e-04 0.114 NA 0.097 NA 0.102 6.8e-05 NA 2.3e-04 NA 1.7e-04
4 GTEx Artery Aorta 0.0990 0.0430 3.0e-04 0.054 NA 0.038 NA 0.059 6.1e-04 NA 3.6e-03 NA 3.5e-04
5 GTEx Artery Coronary 0.1440 0.0700 5.5e-03 0.045 NA 0.029 NA 0.041 1.3e-02 NA 3.6e-02 NA 1.7e-02
6 GTEx Breast Mammary Tissue 0.0840 0.0450 2.1e-03 0.052 NA 0.042 NA 0.037 1.1e-03 NA 3.2e-03 NA 5.4e-03
7 GTEx Breast Mammary Tissue (Male) 0.0810 0.0569 4.0e-02 0.018 NA 0.025 NA 0.051 1.2e-01 NA 8.8e-02 NA 2.6e-02
8 GTEx Breast Mammary Tissue (Female) 0.0155 0.0306 3.3e-01 -0.010 NA 0.004 NA -0.010 9.0e-01 NA 2.4e-01 NA 9.7e-01
9 GTEx Cells EBV-transformed lymphocytes 0.2240 0.0820 4.6e-04 0.048 NA 0.070 NA 0.092 1.1e-02 NA 2.7e-03 NA 6.3e-04
10 GTEx Cells Transformed fibroblasts 0.0910 0.0540 7.9e-03 0.007 NA -0.001 NA 0.004 8.5e-02 NA 3.6e-01 NA 1.5e-01
11 GTEx Esophagus Muscularis 0.0520 0.0300 7.4e-03 0.045 NA 0.038 NA 0.031 9.4e-04 NA 2.4e-03 NA 5.7e-03
12 GTEx Heart Left Ventricle 0.1226 0.0424 2.7e-07 0.093 NA 0.106 NA 0.042 1.1e-05 NA 2.8e-06 NA 2.8e-03
13 GTEx Nerve Tibial 0.0565 0.0298 2.7e-03 0.005 NA 0.000 NA 0.004 1.2e-01 NA 3.1e-01 NA 1.7e-01
14 GTEx Skin Sun Exposed Lower leg 0.0790 0.0290 1.8e-08 0.117 NA 0.100 NA 0.091 6.5e-10 NA 1.1e-08 NA 5.9e-08
15 GTEx Thyroid 0.1290 0.0360 0.0e+00 0.248 NA 0.235 NA 0.230 5.5e-19 NA 6.1e-18 NA 1.4e-17
16 GTEx Whole Blood 0.0510 0.0250 1.1e-04 0.027 NA 0.034 NA 0.044 1.3e-03 NA 3.9e-04 NA 6.4e-05
17 TCGA Colon Adenocarcinoma 0.2850 0.1380 6.5e-03 0.001 0.024 0.065 NA 0.019 2.9e-01 1.4e-02 1.2e-04 NA 2.8e-02
18 TCGA Glioblastoma Multiforme 0.2670 0.1290 8.5e-05 0.143 0.156 0.158 NA 0.146 4.2e-05 1.8e-05 1.6e-05 NA 3.3e-05
19 TCGA Lung Adenocarcinoma 0.0359 0.0231 2.3e-04 0.037 0.031 0.025 NA 0.028 3.1e-05 1.4e-04 5.0e-04 NA 2.7e-04
20 TCGA Prostate Adenocarcinoma 0.0269 0.0175 3.6e-03 0.023 0.021 0.017 NA 0.016 1.6e-03 2.7e-03 5.4e-03 NA 7.0e-03
21 TCGA Thyroid Carcinoma 0.0410 0.0270 2.6e-04 0.032 0.037 0.042 NA 0.026 4.0e-04 1.4e-04 5.5e-05 NA 1.3e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bipolar Disorder (2018) 1.2 2.0 6.7 1.7 -1.3 -0.3 1.7 1.7 -1.8 -2.0 0.0 0.6 1.6 0.2 -1.6 -0.1 -1.4 -1.2 -0.6 0.1 -1.4 -1.4 -2.0 -2.6
Bipolar Disorder or Schizophrenia 3.2 7.9 20.8 4.1 -3.2 0.3 1.8 1.9 -3.7 -2.3 0.0 0.7 3.1 -1.5 -3.1 -1.7 -3.2 -3.1 -2.2 1.7 -3.1 -3.4 -4.3 -4.6
Depressed Affect (Nagel 2018) 3.7 7.8 17.1 -3.7 2.5 -0.9 -2.8 -2.9 3.6 1.2 0.0 -2.6 -2.8 1.6 4.1 2.3 3.0 3.1 2.3 -3.0 3.2 2.6 3.9 2.6
Depression (Nagel 2018) 1.6 2.4 6.5 -2.2 1.2 -0.4 -0.9 -1.0 2.2 0.4 0.0 -1.7 -1.4 1.0 2.6 1.3 1.5 1.5 1.2 -2.0 1.9 1.4 2.2 1.3
Intelligence (Savage-Jansen 2018) 0.5 1.5 3.9 1.3 -0.8 -0.3 1.8 1.7 -2.0 -1.1 0.0 1.1 0.9 -0.5 -1.6 -0.3 -1.3 -1.2 -0.6 1.1 -1.0 -1.0 -1.9 -1.4
Neuroticism (Nagel 2018) 4.2 9.9 24.2 -4.7 2.9 -0.3 -2.5 -2.8 4.3 1.4 0.0 -3.2 -3.2 1.1 4.5 2.1 3.2 3.2 2.2 -3.4 3.5 3.1 4.9 3.7
Schizophrenia (2018) 3.2 6.7 15.6 4.0 -3.1 0.7 0.9 1.1 -3.3 -1.3 0.0 0.5 2.7 -2.1 -2.7 -2.1 -3.0 -3.0 -2.4 2.1 -2.9 -3.3 -3.9 -3.8
Schizophrenia vs Biploar Disorder 0.7 1.0 8.4 -0.4 0.1 1.0 -1.7 -1.6 0.7 2.9 0.0 -0.5 -0.3 -1.3 0.9 -0.8 0.2 0.1 -0.5 0.5 -0.1 0.1 0.7 0.5
Worry (Nagel 2018) 2.2 4.6 13.0 -3.3 2.0 1.1 -1.5 -1.6 2.9 1.8 0.0 -1.8 -2.1 -0.3 3.1 0.4 2.1 2.0 0.8 -1.4 2.3 2.3 3.6 3.4
Alzheimer’s Disease (in mother) 0.4 0.5 1.9 -0.2 -0.6 -0.5 1.0 1.0 -1.4 -0.5 0.0 -0.8 1.0 0.4 -0.7 0.4 -0.4 -0.5 0.0 0.0 0.7 -0.7 -0.6 -0.8
Alzheimer’s Disease (in father) 2.7 2.9 7.7 2.4 -1.7 1.1 -1.4 -1.2 -1.5 0.0 0.0 1.3 0.5 -1.8 -1.0 -1.9 -1.8 -1.8 -1.8 2.8 -2.2 -1.9 -2.3 -2.0
Alzheimer’s Disease (including proxy) 0.5 0.8 4.5 0.8 -1.0 0.3 -0.3 -0.2 -1.3 0.2 0.0 0.3 1.0 -0.7 -0.6 -0.8 -1.0 -1.0 -0.9 2.1 -0.4 -1.2 -1.3 -0.7
Crohns Disease (2017) 0.4 0.9 3.1 0.7 -1.3 1.4 0.4 0.2 -0.4 -0.6 0.0 -1.2 1.3 -0.8 0.0 -1.0 -1.0 -0.9 -1.3 -0.4 -1.1 -1.2 0.0 -1.8
Irritable Bowel Disease (IBD) 0.1 0.2 1.0 0.1 -0.2 0.8 -0.4 -0.6 0.1 0.5 0.0 -0.7 1.0 -0.4 0.7 -0.4 -0.0 -0.1 -0.5 0.3 -0.5 -0.2 0.4 -0.5
Ulcerative Colitis (UC) 0.2 0.5 1.5 -0.3 0.9 0.1 -0.7 -0.9 0.9 1.2 0.0 0.6 0.6 -0.0 0.9 0.2 0.8 0.6 0.3 1.0 -0.2 0.9 0.5 0.7
Major Depression (MDD) 1.0 1.2 4.1 -0.9 0.4 0.1 -2.0 -2.0 0.8 0.2 0.0 -2.0 -0.2 0.6 1.5 0.4 0.9 0.6 0.4 -1.5 1.6 0.1 1.4 -0.2
Reaction Time 3.4 6.5 15.7 2.1 -2.9 3.8 -1.4 -1.3 -1.2 0.9 0.0 -0.2 1.7 -4.0 -1.3 -3.9 -2.8 -2.9 -3.7 3.0 -3.4 -2.8 -1.8 -2.3
Verbal and Numeric Reasoning (VNR) 0.3 0.8 4.2 0.1 -0.0 -1.3 2.1 2.0 -1.1 -0.9 0.0 0.4 0.6 0.5 -1.1 0.8 -0.3 -0.4 0.5 0.0 0.0 -0.2 -1.0 -0.7
Breast Cancer 4.8 11.5 24.2 -3.7 3.8 0.2 -4.0 -3.9 4.5 3.6 0.0 -0.6 -4.1 0.8 4.2 2.0 4.1 4.2 2.3 -2.8 2.5 4.0 4.9 4.1
Ovarian Cancer 0.1 0.1 0.5 -0.7 0.4 0.2 0.7 0.5 -0.3 0.4 0.0 0.4 0.1 -0.6 0.1 0.2 0.2 0.1 0.1 0.0 -0.6 0.4 0.3 -0.1
Prostate Cancer 0.6 0.9 3.9 0.7 0.6 -2.0 1.0 0.9 -0.7 -0.5 0.0 1.8 -0.8 1.0 -0.5 1.4 0.4 0.3 1.2 -1.3 -0.3 0.5 -1.0 -0.4
Age at First Birth 1.7 2.5 9.0 2.9 -0.3 -2.2 0.8 1.0 -2.7 -1.6 0.0 2.8 1.4 1.3 -1.3 1.0 -0.4 -0.2 0.6 0.6 -0.9 -0.5 -3.0 -1.6
Bipolar Disorder (2011) 1.2 1.1 3.9 2.0 -1.1 0.1 0.5 0.5 -1.9 -0.5 0.0 1.0 1.1 -0.6 -1.2 -0.8 -1.2 -1.2 -0.8 0.9 -1.2 -1.0 -1.8 -0.6
Body Mass Index (BMI) (2010) 0.2 0.3 1.2 1.0 -0.1 -0.0 0.2 0.0 -0.4 -0.1 0.0 0.8 1.1 -0.2 0.1 0.1 -0.2 -0.2 -0.2 0.1 -0.9 -0.2 -0.7 -1.1
Coronary Artery Disease (CAD) 0.6 0.7 4.8 -0.5 0.8 -1.0 -0.1 -0.0 0.9 2.2 0.0 0.6 -1.3 0.8 0.5 0.9 0.7 0.8 0.9 -0.1 0.2 0.8 0.3 0.8
Crohns Disease (2012) 0.8 1.3 4.9 0.5 -1.6 1.6 -0.0 -0.0 -0.7 -1.1 0.0 -2.2 1.4 -1.0 -0.2 -1.3 -1.2 -1.0 -1.5 0.3 -0.2 -1.6 0.1 -1.7
Mean Putamen Volume 1.3 1.5 6.0 -1.0 1.4 -1.0 -1.0 -1.1 1.5 1.1 0.0 0.3 -2.4 1.0 1.2 1.1 1.4 1.3 1.3 -0.4 1.3 1.3 0.9 1.5
Fasting Glucose 0.2 0.2 1.1 0.8 0.4 0.4 -0.4 -0.4 -0.1 0.3 0.0 1.1 -0.7 0.1 0.4 0.1 0.6 0.4 -0.1 0.4 0.3 0.5 -0.3 0.7
HbA1C 0.5 0.5 2.3 0.5 0.4 1.1 -0.7 -0.7 0.4 1.2 0.0 1.3 -0.6 -0.8 0.2 -0.7 0.0 -0.2 -0.8 1.5 -0.8 0.0 -0.6 0.2
HDL Cholesterol 1.6 2.6 7.1 1.0 -2.0 1.9 -0.3 -0.3 -1.7 -1.1 0.0 -1.0 1.1 -2.0 -1.5 -2.7 -2.0 -2.2 -2.2 2.3 -0.8 -2.1 -1.1 -0.8
LDL Cholesterol 0.6 1.0 3.2 -0.8 1.1 -1.6 1.0 1.0 0.4 0.1 0.0 0.4 -0.7 1.7 0.1 1.8 1.0 1.2 1.5 -0.9 0.7 1.1 0.4 0.0
Lupus 1.1 1.6 6.2 -0.5 -1.8 1.3 0.3 0.4 -1.0 -1.7 0.0 -2.5 2.2 -0.5 -1.3 -1.4 -1.4 -1.2 -1.4 -1.0 0.6 -1.7 0.2 -0.9
Neuroticism (2016) 2.8 4.1 13.0 -2.9 1.9 0.1 -2.0 -2.2 2.6 2.0 0.0 -0.9 -2.2 0.3 3.6 1.1 2.4 2.2 1.3 -0.8 1.6 2.1 3.3 2.0
Primary Biliary Cirrhosis 0.2 0.3 1.6 0.3 0.6 -0.8 -0.5 -0.4 -0.0 0.8 0.0 1.3 -0.7 0.9 0.1 0.4 0.6 0.6 0.6 0.3 0.5 0.4 -0.3 0.5
Rheumatoid Arthritis 0.2 0.2 1.3 0.0 -0.2 -0.3 0.1 0.0 0.5 -0.5 0.0 -1.0 0.9 0.5 0.2 0.5 0.0 0.2 0.1 -1.2 0.3 -0.2 0.5 -0.5
Schizophrenia (2014) 2.7 6.0 16.4 4.0 -2.7 0.2 1.3 1.3 -3.4 -1.0 0.0 0.8 2.5 -1.6 -2.8 -1.7 -2.7 -2.9 -1.9 2.0 -2.6 -2.9 -3.9 -3.6
Triglycerides 0.7 1.2 3.6 1.1 0.1 -1.1 1.7 1.6 -0.9 1.1 0.0 1.9 1.6 0.8 -0.8 0.9 -0.4 -0.2 0.4 -0.3 -1.4 -0.1 -1.5 -1.2
Type 2 Diabetes (T2D) (2012) 2.7 3.1 10.0 1.8 -1.8 1.5 1.3 1.2 -1.1 -1.4 0.0 0.4 2.6 -1.9 -2.0 -1.3 -2.0 -2.0 -2.0 -0.0 -2.8 -1.8 -1.5 -3.2
Ulcerative Colitis 0.7 1.0 5.7 -0.9 0.6 0.7 -1.6 -1.7 1.1 1.5 0.0 0.8 -2.4 -0.6 0.8 -0.3 0.6 0.5 -0.1 -0.0 -0.2 0.8 0.9 0.9
Blood Eosinophil Count 0.2 1.8 5.1 2.3 -0.7 2.1 -1.7 -2.1 0.2 1.8 0.0 0.1 0.5 -1.4 1.9 -1.9 -0.6 -0.7 -1.6 1.4 -1.3 -0.6 -0.3 -0.2
Blood Platelet Count 0.5 5.5 10.8 -2.8 3.3 -1.7 -0.3 -0.3 3.1 2.4 0.0 0.6 -3.0 1.5 2.2 2.8 3.0 3.0 2.8 -1.3 1.9 3.3 2.8 2.4
Blood Red Count 0.2 2.0 8.5 -0.0 2.2 0.4 0.5 0.4 0.9 2.6 0.0 2.9 -0.9 -0.8 0.8 0.1 1.1 1.3 0.6 2.0 -1.2 2.2 0.5 2.1
Blood White Count 0.9 7.0 21.6 1.9 -2.6 4.7 0.9 0.5 -0.9 1.7 0.0 -0.6 1.9 -4.6 -1.0 -4.3 -3.2 -3.3 -4.0 3.0 -3.0 -2.5 -1.0 -1.5
Heel T-Score 0.1 0.9 3.5 1.9 -0.5 0.6 -1.6 -1.7 0.8 0.6 0.0 0.6 0.6 -0.5 0.3 -1.2 -0.7 -0.8 -0.8 1.1 -1.4 -0.5 -0.6 0.0
BMI 0.1 0.4 2.0 0.5 0.2 0.3 -0.4 -0.3 1.2 0.7 0.0 -0.8 1.4 -0.2 -0.1 -0.5 0.2 0.1 -0.0 0.8 0.7 0.2 0.3 1.1
Height 0.1 1.8 11.7 2.3 -0.3 -1.1 0.7 0.4 -2.5 0.6 0.0 3.4 1.5 0.5 0.0 0.2 -0.4 -0.4 0.0 0.7 -1.9 -0.2 -2.4 0.2
Waist Hip Ratio (WHR) 0.9 4.2 11.7 1.8 -1.7 2.3 2.8 2.4 -1.1 -0.0 0.0 1.1 2.2 -2.1 -2.0 -2.4 -2.5 -2.5 -2.4 0.9 -3.4 -1.5 -1.6 -2.0
Systolic Blood Pressure 0.3 1.6 6.9 1.7 -0.1 0.1 1.6 1.7 -1.1 -2.0 0.0 2.6 -0.1 -0.8 -2.0 -0.5 -0.5 -0.6 -0.4 0.0 -2.3 -0.0 -1.4 -0.2
Smoking Status 1.1 2.7 7.4 1.5 -2.0 2.1 -0.0 -0.1 0.1 -2.0 0.0 -0.8 1.0 -1.9 -1.2 -2.3 -2.0 -2.2 -2.2 -0.9 -2.7 -1.8 -0.5 -2.1
Allergy or Eczema 1.0 2.6 7.2 2.5 -1.4 -0.8 2.3 2.4 -1.1 -1.5 0.0 0.9 1.2 0.4 -2.7 -0.2 -1.2 -1.4 -0.6 0.4 -1.9 -1.5 -2.4 -2.2
Cardiovascular Disease 0.5 1.7 5.1 1.0 -1.2 1.8 1.0 0.9 -0.5 -1.7 0.0 0.3 0.9 -2.3 -1.6 -2.1 -1.6 -1.7 -1.8 0.7 -1.3 -1.1 -0.8 -0.3
Hypothyroidism (self reported) 1.2 2.7 6.7 0.7 -2.4 2.1 -1.4 -1.3 -0.8 -1.4 0.0 -2.6 1.5 -2.0 -0.6 -2.4 -1.7 -1.8 -2.2 1.1 -0.2 -2.4 -0.4 -1.4
Respiratory disease 1.0 2.2 7.2 0.5 -0.8 2.4 -2.6 -2.7 0.6 1.9 0.0 -0.6 -0.1 -2.0 1.3 -2.1 -0.7 -0.7 -1.7 2.4 -0.5 -0.7 0.3 0.1
Type 2 Diabetes (T2D) (2018) 2.7 5.0 10.0 2.3 -2.6 1.8 1.8 1.6 -1.8 -1.6 0.0 0.0 3.2 -2.5 -3.0 -2.6 -2.9 -3.1 -2.6 1.7 -1.8 -2.6 -2.3 -1.8
Lung FEV1/FVC ratio 2.8 14.4 34.0 -4.3 5.7 -2.5 -0.4 -0.4 3.9 3.0 0.0 1.1 -0.3 3.0 3.8 4.3 4.9 5.0 4.5 -3.5 3.7 5.8 4.5 5.3
Lung FVC 0.3 1.7 6.2 0.0 -0.0 -2.2 2.5 2.4 -1.5 -0.1 0.0 0.8 -1.0 2.0 -0.9 1.8 -0.1 0.3 1.1 -0.7 0.4 -0.2 -1.1 -1.5
Neuroticism 3.2 7.7 18.8 -4.2 2.1 0.2 -2.9 -3.0 3.9 1.1 0.0 -3.0 -3.6 0.8 4.0 1.4 2.5 2.6 1.5 -2.9 3.1 2.3 4.3 2.7
Chronotype (morning person) 0.6 1.4 5.5 0.8 -0.5 0.1 2.3 2.3 -1.2 0.1 0.0 0.6 1.8 -0.6 -2.3 -0.3 -0.8 -0.9 -0.5 1.0 -0.8 -0.6 -1.2 -0.9
Hair Pigment 0.4 12.2 27.8 2.0 -4.8 4.7 -1.9 -2.0 -3.2 -1.0 0.0 -2.9 1.9 -4.9 -1.7 -5.3 -4.6 -4.6 -5.1 2.7 -2.8 -4.7 -1.9 -3.1
Tanning 0.1 0.9 7.2 -0.3 -0.7 0.2 1.3 1.5 0.1 -2.7 0.0 -0.6 -0.1 -0.2 -2.0 -0.3 -0.8 -0.6 -0.5 0.0 -0.2 -0.7 -0.4 -0.8
Hand grip strength (left) 3.2 8.3 23.0 -0.3 3.9 -4.8 1.7 1.5 1.8 1.5 0.0 4.5 -2.1 4.2 1.1 4.5 3.3 3.5 4.3 -1.0 1.2 3.6 0.0 2.3
Number of treatments/medications taken 0.9 1.6 5.2 1.2 -1.6 2.2 -0.8 -1.0 -0.1 0.6 0.0 -0.9 0.9 -1.8 -0.0 -2.3 -1.5 -1.6 -2.1 0.7 -0.4 -1.5 -0.5 -0.4
Average weekly spirits intake 0.8 1.0 5.1 0.3 -0.5 1.0 -2.2 -2.3 0.8 0.5 0.0 -1.2 -1.7 -0.8 1.1 -1.0 -0.3 -0.2 -0.8 0.4 -0.4 -0.4 0.4 0.2
Sensitivity / hurt feelings 2.4 4.0 8.9 -2.8 1.7 -1.2 -1.0 -0.9 2.5 0.3 0.0 -2.1 -3.0 1.6 2.0 2.0 2.0 2.1 1.9 -2.9 2.5 1.8 2.6 1.9
Frequency of depressed mood in last 2 weeks 1.4 2.0 6.4 -2.3 1.1 -0.5 -1.0 -1.0 1.7 0.7 0.0 -1.6 -1.2 1.0 2.5 1.2 1.3 1.4 1.2 -1.2 1.9 1.1 2.0 1.3
Hearing difficulty/problems: Yes 0.4 0.7 2.9 -0.2 -0.2 0.7 -1.1 -1.5 0.5 1.6 0.0 -1.2 -0.2 -0.7 1.7 0.2 -0.1 0.1 -0.3 -1.3 0.5 -0.0 0.6 -0.4
Relative age of first facial hair 0.3 0.7 2.9 -1.3 1.2 0.2 0.6 0.3 0.9 0.9 0.0 1.0 0.5 -0.3 0.9 0.3 0.7 0.7 0.5 0.5 0.3 1.3 1.0 1.7
Other serious medical condition/disability diagnosed by doctor 5.3 6.9 16.2 2.9 -4.0 2.1 -0.1 -0.1 -2.2 -1.9 0.0 -1.7 3.0 -2.3 -1.9 -3.0 -3.5 -3.4 -3.2 0.2 -2.7 -4.0 -2.3 -3.9
Ever used hormone-replacement therapy (HRT) 0.3 0.4 0.8 0.3 -0.9 0.7 -0.9 -0.8 -0.3 -0.3 0.0 -0.8 -0.2 -0.7 -0.5 -0.7 -0.7 -0.6 -0.8 0.2 -0.2 -0.9 -0.3 -0.9
Ever had hysterectomy (womb removed) 0.9 1.1 4.0 0.0 -1.6 1.0 0.5 0.6 -0.3 0.1 0.0 -2.0 0.5 -0.5 -1.1 -0.9 -1.2 -1.3 -1.3 0.4 0.3 -1.8 -0.1 -1.7
Systolic blood pressure, automated reading 1.0 2.8 6.9 2.1 -1.7 1.4 1.3 1.3 -1.6 -1.8 0.0 0.7 0.0 -2.2 -2.4 -1.9 -1.9 -2.0 -1.9 0.5 -2.6 -1.6 -1.8 -1.5
Eye problems/disorders: Diabetes related eye disease 3.1 3.4 8.0 1.7 -2.5 1.6 0.2 0.0 -2.6 -1.0 0.0 -0.8 2.0 -1.9 -1.9 -2.2 -2.5 -2.8 -2.3 1.0 -1.4 -2.5 -1.9 -2.1
Angina 0.9 1.2 9.9 -0.8 -1.3 1.4 -0.4 -0.4 -0.5 -0.6 0.0 -3.1 1.3 -0.6 -0.2 -1.1 -0.9 -0.9 -1.2 -0.6 0.5 -1.2 0.6 -0.9
Medication for hormone replacement therapy 1.6 1.7 5.8 2.1 -1.4 -1.8 -0.5 -0.2 -2.2 -2.4 0.0 0.5 0.6 1.4 -1.5 0.2 -0.8 -0.8 0.1 -0.8 0.8 -1.4 -2.4 -1.0
Vitamin and mineral supplements 0.4 0.6 1.7 0.5 -0.2 0.9 1.2 1.2 1.3 -0.4 0.0 0.2 1.1 -1.0 -0.8 -0.8 -0.4 -0.5 -0.7 0.8 -1.3 -0.2 0.2 -0.2
Supplements: Zinc 2.3 2.5 6.4 -1.6 1.3 -1.5 -0.6 -0.6 0.7 0.1 0.0 -1.1 -2.0 2.0 2.5 2.1 1.7 1.9 1.8 -2.1 2.3 1.3 1.5 1.1
Medication: Co-codamol 2.2 2.6 9.8 -0.8 -1.6 3.1 -1.8 -1.7 -0.3 0.8 0.0 -3.0 0.7 -2.6 0.3 -2.2 -1.4 -1.3 -2.3 0.4 -1.0 -1.4 0.9 -1.0
Medication: Metformin 3.3 4.7 10.1 0.9 -2.5 2.4 2.0 1.7 -2.5 -1.0 0.0 -0.6 3.2 -2.5 -2.3 -2.6 -2.9 -2.9 -2.7 1.3 -2.0 -2.4 -1.4 -2.3
Diabetes (father) 6.1 7.6 16.1 2.7 -3.7 3.1 0.5 0.1 -2.6 -2.0 0.0 -1.1 2.5 -3.1 -2.5 -3.7 -3.8 -4.0 -3.8 0.3 -3.2 -3.5 -2.3 -2.8
Diabetes (mother) 3.3 4.2 10.2 3.1 -1.4 -0.3 2.6 2.5 -2.8 -2.6 0.0 2.1 2.6 -0.8 -2.8 -0.8 -1.9 -2.0 -1.0 0.9 -1.9 -1.5 -3.2 -1.8
Severe depression (siblings) 0.5 0.6 4.2 -0.2 0.8 -0.6 -0.5 -0.4 0.8 2.1 0.0 0.1 -1.3 0.3 1.1 0.7 0.8 0.7 0.7 0.4 0.1 0.7 0.3 0.5
Pack years adult smoking proportion 0.8 1.3 7.3 -1.3 -1.3 1.6 -0.2 -0.2 -0.2 -1.5 0.0 -2.7 0.7 -1.0 -0.4 -1.3 -0.8 -1.0 -1.2 -0.8 0.9 -1.3 1.1 -0.7
Impedance of leg (right) 0.1 0.3 2.2 -0.8 0.3 0.5 -0.1 -0.2 0.5 -0.7 0.0 -0.2 0.2 -0.1 0.2 0.1 0.3 0.3 0.0 -1.5 -0.5 0.5 1.0 0.2
Leg fat-free mass (left) 0.2 1.0 4.2 0.1 1.5 -1.2 0.2 0.2 0.5 0.8 0.0 1.5 -0.1 1.0 0.5 0.8 1.2 1.0 1.3 1.1 1.0 1.4 -0.0 2.1
Trunk fat percentage 0.2 0.9 4.5 -0.3 1.4 -0.2 -0.2 -0.2 1.5 0.0 0.0 -0.2 0.1 0.4 0.8 0.4 1.2 1.2 0.9 -0.1 0.6 1.5 1.2 2.1
Hand grip strength (right) 2.3 6.2 22.4 -0.2 3.5 -4.0 1.6 1.4 1.1 1.1 0.0 4.7 -1.8 3.3 0.6 3.6 2.8 2.9 3.6 0.2 0.5 3.2 -0.3 2.1
Townsend deprivation index at recruitment 1.0 1.4 4.2 1.2 -1.6 0.9 -1.5 -1.4 -0.5 -0.7 0.0 -0.6 0.4 -1.2 -0.6 -1.3 -1.3 -1.2 -1.4 0.4 -1.6 -1.6 -1.1 -2.0
Current tobacco smoking 0.6 1.0 4.5 -1.0 0.3 0.8 -1.2 -1.4 1.5 -1.0 0.0 -0.9 -1.5 -0.2 1.3 -0.1 0.4 0.4 -0.1 -2.1 -0.5 0.6 1.7 -0.0
Average weekly fortified wine intake 0.2 0.3 1.2 0.7 -0.5 0.3 0.9 0.6 -1.1 0.4 0.0 0.4 0.2 -0.3 0.3 -0.2 -0.5 -0.5 -0.5 -0.5 -0.3 -0.5 -0.5 -0.4
Maternal smoking around birth 0.7 1.0 4.4 -0.7 -0.6 2.1 -0.4 -0.4 0.8 0.2 0.0 -2.1 0.6 -1.2 0.5 -1.5 -0.5 -0.5 -1.2 -0.8 -0.5 -0.3 1.6 0.2
Fed-up feelings 5.2 9.5 22.6 -3.9 2.7 -0.8 -3.5 -3.6 3.6 1.7 0.0 -2.6 -3.7 2.1 4.8 2.5 3.3 3.5 2.4 -3.0 3.1 2.9 4.2 2.7
Frequency of unenthusiasm / disinterest in last 2 weeks 1.2 1.6 4.7 -2.2 1.3 -0.4 -0.2 -0.2 1.7 0.8 0.0 -1.1 -0.9 0.9 1.8 1.2 1.3 1.4 1.2 -1.7 1.2 1.4 1.9 1.0
Relative age voice broke 0.3 0.5 2.8 -0.4 0.5 0.8 -0.5 -0.8 0.1 1.2 0.0 1.1 -1.7 -0.7 0.9 -0.5 0.0 0.1 -0.3 1.0 -0.4 0.5 0.2 0.8
Taking other prescription medications 0.8 1.2 5.3 -0.0 -1.0 2.3 -1.0 -1.1 0.6 0.7 0.0 -1.3 0.4 -1.9 0.3 -1.9 -0.9 -0.9 -1.7 0.8 0.0 -0.9 0.5 0.1
Age when periods started (menarche) 0.4 1.0 2.5 -0.8 0.7 -0.7 -1.5 -1.3 0.8 1.6 0.0 -0.1 -1.2 1.1 1.5 1.1 1.0 1.2 0.9 -0.3 0.9 0.7 0.8 -0.2
Bilateral oophorectomy (both ovaries removed) 0.6 0.6 3.4 -1.1 -0.4 1.4 0.2 0.4 -0.1 0.0 0.0 -1.8 0.9 -1.1 -0.9 -0.8 -0.2 -0.2 -0.8 1.0 0.6 -0.4 0.8 0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.8 4.4 1.3 -1.7 1.8 -1.3 -1.3 0.1 0.2 0.0 -1.0 1.4 -1.8 0.3 -2.1 -1.6 -1.6 -1.9 1.0 -1.1 -1.7 -0.4 -1.1
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 3.9 -0.3 0.7 0.4 0.3 0.2 2.0 0.9 0.0 0.2 -0.4 -0.5 0.3 -0.3 0.4 0.1 0.1 0.4 0.0 0.8 0.6 1.2
Qualifications: CSEs or equivalent 1.6 2.1 5.1 -0.8 2.2 -0.9 -0.3 -0.4 2.3 2.1 0.0 1.9 -2.0 0.4 1.5 1.4 1.8 1.7 1.5 0.0 0.2 2.1 1.0 1.6
Serious illness, injury or assault to yourself 2.4 2.9 10.3 0.6 -2.5 0.1 1.1 1.4 -2.4 -2.2 0.0 -2.9 1.1 0.0 -1.8 -0.7 -1.9 -1.8 -1.2 -1.0 -0.4 -2.6 -1.1 -3.2
High blood pressure 1.9 5.3 10.5 2.3 -2.5 1.9 2.1 2.1 -2.1 -2.0 0.0 0.8 2.0 -2.5 -3.2 -2.8 -3.0 -2.9 -2.7 1.5 -2.6 -2.5 -2.6 -1.8
Hayfever, allergic rhinitis or eczema 0.4 0.8 2.6 1.6 -0.5 -0.9 1.2 1.4 -0.2 -0.8 0.0 0.6 0.0 0.6 -1.5 0.2 -0.3 -0.6 0.0 0.7 -0.7 -0.7 -1.4 -1.2
Multivitamins +/- minerals 0.4 0.5 2.2 -0.1 -0.3 -0.8 -0.9 -1.0 -1.5 -0.8 0.0 -0.3 -0.6 0.6 0.4 0.6 0.0 0.1 0.4 -1.2 1.2 -0.3 -0.5 -0.3
Stomach or abdominal pain in last month 1.8 2.2 5.8 -2.4 1.7 -1.6 0.9 1.0 1.4 1.2 0.0 -0.3 0.2 1.9 0.8 1.8 1.7 1.7 2.0 -0.5 2.3 1.6 1.6 1.6
Supplements: Glucosamine 2.5 3.3 8.3 -0.8 2.2 -2.9 1.2 1.2 0.9 0.5 0.0 2.6 -0.9 2.6 0.1 2.6 2.0 2.0 2.7 -0.8 2.1 2.1 0.1 2.3
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 2.2 0.3 0.1 0.4 1.5 1.4 0.7 1.3 0.0 0.4 0.6 -0.1 -0.6 -0.2 -0.3 -0.3 -0.2 0.6 -0.6 0.1 -0.0 -0.1
Medication: Atenolol 0.6 0.7 2.0 -0.9 0.2 1.4 -1.1 -1.2 1.3 0.1 0.0 -1.4 -1.0 -0.5 1.0 -0.7 0.2 0.2 -0.5 -0.0 0.3 0.4 1.3 1.1
Medication: Levothyroxine sodium 1.9 3.2 8.0 0.8 -2.4 2.5 -0.9 -0.7 -1.2 -1.5 0.0 -2.5 1.8 -2.6 -1.2 -2.8 -2.1 -2.2 -2.6 0.9 -0.6 -2.4 -0.5 -1.1
Sitting height 0.3 2.0 8.0 1.4 -0.5 -0.1 2.2 2.0 -2.3 -0.7 0.0 2.8 1.9 -0.5 -1.4 -0.5 -1.0 -1.0 -0.6 1.0 -1.6 -0.6 -1.9 -0.7
Chronic bronchitis/emphysema (father) 0.3 0.3 1.8 -0.0 -0.1 0.1 -1.2 -1.3 1.0 0.2 0.0 -0.1 -0.0 0.7 0.9 -0.0 0.4 0.3 0.0 -0.6 0.2 0.1 0.6 0.3
High blood pressure (mother) 0.2 0.3 3.3 0.9 -0.1 -0.1 0.4 0.5 0.0 0.4 0.0 0.4 -0.0 -0.6 -0.5 -0.3 -0.4 -0.5 -0.2 1.8 -0.1 -0.3 -0.9 -0.0
Body mass index (BMI) 0.1 0.3 1.4 0.2 0.3 0.4 -0.1 -0.1 1.2 0.7 0.0 -0.8 0.2 -0.3 0.0 -0.6 0.1 -0.0 -0.1 1.1 0.4 0.3 0.3 1.1
Impedance of leg (left) 0.1 0.3 2.3 -0.5 0.5 -0.0 0.4 0.2 0.4 -0.5 0.0 0.4 0.3 0.2 0.4 0.5 0.3 0.4 0.3 -1.5 -0.7 0.6 0.8 -0.1
Leg predicted mass (left) 0.2 0.9 3.8 0.1 1.5 -1.2 0.3 0.3 0.5 0.7 0.0 1.5 -0.1 1.0 0.4 0.8 1.1 1.0 1.2 1.0 0.9 1.3 -0.1 1.9
Trunk fat mass 0.2 0.7 4.2 -0.1 1.4 -0.2 -0.0 -0.1 1.3 0.4 0.0 0.1 0.4 0.3 0.8 0.2 1.1 1.0 0.8 0.5 0.5 1.4 0.9 2.0
Waist circumference 0.1 0.5 2.8 0.6 -0.1 1.1 0.4 0.2 0.3 0.8 0.0 0.0 0.4 -1.1 -0.3 -1.2 -0.5 -0.7 -0.8 1.7 -0.6 -0.1 -0.3 0.6
Number of incorrect matches in round 0.2 0.3 2.6 0.2 -0.6 0.0 0.2 0.1 0.2 -1.0 0.0 -0.2 1.6 -0.0 -0.5 0.0 -0.5 -0.1 -0.2 -1.2 -0.1 -0.6 -0.2 -0.8
Past tobacco smoking 5.0 9.3 18.5 -3.7 3.8 -2.7 -1.2 -1.1 2.0 2.2 0.0 0.0 -3.0 3.1 3.4 3.7 4.0 4.3 3.8 -0.7 4.3 3.7 2.9 3.5
Alcohol usually taken with meals 0.8 1.3 5.2 1.4 0.5 -1.1 1.7 1.6 -2.0 -0.4 0.0 2.3 1.4 0.6 -0.4 0.5 0.0 0.1 0.5 1.1 -1.3 0.4 -1.4 -0.1
Nervous feelings 2.5 4.6 10.7 -3.3 2.4 0.0 -1.4 -1.6 2.6 2.6 0.0 -1.1 -2.4 0.7 3.0 1.2 2.3 2.4 1.5 -0.7 2.3 2.5 3.2 3.2
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.6 6.0 -1.6 0.7 0.3 -1.9 -2.0 1.3 1.2 0.0 -1.0 -1.5 0.3 2.4 0.3 0.8 0.9 0.5 -0.9 1.1 0.8 1.7 1.2
Hearing difficulty/problems with background noise 0.6 1.0 4.8 -0.5 -0.2 1.3 -1.6 -2.0 0.4 2.0 0.0 -1.0 -0.4 -0.7 2.2 -0.6 -0.2 0.1 -0.6 0.5 0.6 -0.1 0.7 0.1
Hair/balding pattern: Pattern 2 1.0 1.2 11.0 -1.5 0.8 0.4 0.3 0.2 0.6 0.4 0.0 -1.1 0.6 0.4 1.3 0.6 0.8 1.0 0.4 -3.3 0.5 1.2 1.8 0.8
Had menopause 0.8 1.0 2.6 1.6 -1.0 0.1 0.8 0.8 -1.0 -0.7 0.0 0.8 0.8 -0.5 -1.4 -0.9 -1.1 -1.1 -0.8 1.3 -0.7 -1.1 -1.6 -0.8
Had other major operations 0.6 0.7 2.9 -1.7 0.4 0.2 -1.0 -0.9 -0.3 -0.8 0.0 -0.9 -1.4 0.2 0.9 0.1 0.6 0.6 0.4 -0.9 0.7 0.6 1.4 0.9
Forced vital capacity (FVC) 0.4 1.4 4.3 -0.2 1.2 -2.1 1.2 1.0 -1.1 1.0 0.0 1.9 -1.2 2.0 0.3 1.8 0.9 1.0 1.6 0.3 0.5 1.0 -0.6 0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.9 2.2 4.3 1.7 -1.8 1.7 -1.7 -1.7 -0.5 -0.1 0.0 -0.5 1.5 -1.6 0.3 -2.1 -1.7 -1.6 -2.0 0.9 -1.8 -1.8 -1.0 -1.6
Ever unenthusiastic/disinterested for a whole week 0.1 0.1 0.4 0.2 0.2 -0.5 -0.6 -0.6 0.1 0.2 0.0 0.3 0.2 0.5 0.6 0.3 0.2 0.2 0.3 -0.1 -0.6 0.2 -0.1 -0.2
Qualifications: None of the above 1.4 2.9 14.6 -1.6 -1.2 2.4 -3.1 -3.1 0.9 1.4 0.0 -3.8 0.2 -1.2 1.0 -1.5 -0.5 -0.7 -1.4 -1.2 1.2 -0.9 1.8 -0.1
Financial difficulties in last 2 years 0.8 1.1 2.4 -0.8 -1.2 0.4 1.4 1.5 -1.6 -1.0 0.0 -1.5 1.4 -0.2 -1.2 -0.5 -1.0 -1.0 -0.7 -0.0 0.3 -1.3 -0.2 -1.4
Mouth/teeth dental problems 0.8 1.3 4.2 1.4 -1.4 -0.3 0.3 0.5 -2.0 -2.1 0.0 -0.2 1.2 -0.2 -1.7 -0.6 -0.9 -1.2 -0.6 0.5 -0.3 -1.5 -1.5 -1.1
Heart attack 1.6 2.1 8.5 0.2 -1.4 2.9 -1.2 -1.2 0.1 0.1 0.0 -1.8 0.8 -2.6 0.3 -2.4 -1.4 -1.4 -2.2 0.7 -1.4 -1.2 0.4 -0.7
Allergy 1.1 2.6 5.7 -2.4 2.0 -1.5 -0.4 -0.4 0.8 0.5 0.0 -0.2 -0.4 1.5 1.6 2.0 1.9 2.2 2.1 -1.6 2.3 2.0 1.8 2.2
Pain all over the body in last month 0.8 0.9 3.8 0.8 -1.1 0.5 0.2 0.2 -0.8 -1.2 0.0 -1.3 1.9 -0.5 -0.4 -0.6 -1.1 -0.9 -0.9 -1.5 0.2 -1.0 -0.6 -0.9
Diabetes (self-reported) 1.9 2.9 8.2 1.1 -1.9 2.0 0.9 0.7 -1.7 -0.8 0.0 -0.7 2.9 -2.4 -1.7 -2.3 -2.2 -2.4 -2.2 1.6 -1.0 -1.9 -1.2 -1.1
Hayfever/allergic rhinitis (self-reported) 1.3 1.7 6.9 1.8 -1.3 -0.4 1.3 1.7 -0.7 -1.6 0.0 0.7 0.6 0.0 -2.6 -0.6 -1.2 -1.3 -0.7 1.4 -1.2 -1.5 -2.0 -1.4
Medication: Ramipril 0.9 1.2 2.8 -0.6 1.7 -1.1 1.2 1.3 1.2 -0.2 0.0 1.1 -0.3 1.1 0.1 1.2 1.2 1.4 1.4 -0.5 0.6 1.7 0.7 1.7
Medication: Simvastatin 0.2 0.4 1.5 0.3 -0.2 1.1 -0.6 -0.7 -0.2 -1.2 0.0 -0.1 0.2 -1.1 0.1 -1.0 -0.4 -0.4 -0.8 -0.2 -0.7 -0.1 0.0 0.4
Fluid intelligence score 0.2 0.4 1.2 0.5 -0.7 0.2 1.1 1.0 -0.8 -0.7 0.0 -0.3 0.6 -0.6 -0.7 -0.4 -0.8 -0.8 -0.6 0.3 -0.6 -0.8 -0.8 -0.7
Illnesses of siblings 2.2 3.1 7.8 -2.1 1.9 -1.1 -2.2 -2.2 1.4 1.2 0.0 0.7 -2.8 1.0 2.3 1.6 2.1 2.1 1.8 -1.0 1.6 2.0 1.8 1.9
Neuroticism score 3.9 8.0 19.4 -3.8 2.1 -0.1 -3.5 -3.5 3.6 1.5 0.0 -2.7 -3.9 1.2 4.4 1.6 2.6 2.8 1.7 -2.9 2.8 2.4 4.1 2.7
Weight 0.1 0.5 2.7 0.3 1.0 -0.4 0.2 0.1 0.8 0.9 0.0 0.7 0.2 0.3 0.3 0.1 0.6 0.5 0.6 1.4 0.4 0.9 0.0 1.6
Impedance of arm (right) 0.4 1.7 5.0 -0.8 1.6 -1.7 0.1 0.2 0.7 -0.8 0.0 0.8 -1.4 1.6 0.5 2.1 1.7 1.8 1.8 -2.2 0.3 1.6 1.0 0.7
Arm fat percentage (right) 0.1 0.5 2.2 0.0 1.1 -0.3 -0.0 -0.0 1.4 0.4 0.0 -0.5 -0.1 0.3 0.4 0.3 0.9 0.8 0.8 0.2 0.5 1.1 0.7 1.5
Trunk fat-free mass 0.1 0.5 3.4 0.6 0.5 -0.7 0.8 0.7 -0.3 1.0 0.0 1.4 0.5 0.3 0.0 0.2 0.1 0.0 0.4 1.8 0.2 0.3 -0.9 0.5
Hip circumference 0.2 0.9 4.0 -0.1 1.1 -0.8 -1.2 -1.1 0.9 0.9 0.0 0.2 -0.9 0.6 0.9 0.4 1.1 0.9 1.0 1.2 1.2 1.0 0.4 2.0
Time employed in main current job 0.4 0.5 2.4 0.7 0.2 0.1 -1.2 -1.5 -0.7 0.2 0.0 1.3 -0.1 -0.2 1.5 -0.1 0.1 0.4 -0.0 0.7 0.4 0.2 -0.3 0.6
Alcohol intake versus 10 years previously 0.7 1.0 2.8 0.4 -1.6 0.9 -0.3 -0.2 -0.0 -0.3 0.0 -1.7 0.1 -0.5 -1.3 -1.1 -1.4 -1.3 -1.1 1.4 -0.3 -1.6 -0.6 -1.4
Father’s age at death 0.7 0.9 3.6 -0.1 -0.3 1.4 -1.6 -1.9 0.4 1.4 0.0 0.1 -1.3 -1.5 1.4 -0.7 -0.3 -0.2 -0.8 1.0 -0.1 -0.2 0.4 -0.2
Worrier / anxious feelings 3.7 7.0 15.9 -3.6 3.1 -0.4 -1.5 -1.6 3.3 2.3 0.0 -0.4 -2.3 1.1 3.8 1.8 3.1 3.2 2.2 -2.5 2.4 3.5 3.8 4.0
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 5.4 -0.7 -0.8 0.9 -2.3 -2.3 -0.1 0.4 0.0 -2.2 -0.1 -0.5 1.3 -0.6 -0.4 -0.3 -0.6 -1.3 0.3 -0.6 0.6 -0.4
Falls in the last year 0.2 0.3 1.0 0.6 -0.6 0.6 -0.8 -0.7 0.4 -0.3 0.0 -0.5 -0.3 -0.4 0.2 -0.7 -0.3 -0.6 -0.5 -1.0 -0.4 -0.4 0.1 -0.2
Hair/balding pattern: Pattern 3 1.6 2.4 8.2 2.2 -0.9 0.8 0.4 0.4 -0.8 -0.3 0.0 2.5 0.2 -1.9 -1.7 -1.5 -1.4 -1.4 -1.3 2.6 -2.9 -1.0 -2.1 -0.9
Number of live births 0.4 0.6 1.9 -1.0 0.5 -1.0 0.9 0.8 0.7 -0.1 0.0 -0.6 -1.4 1.3 -0.1 1.2 0.4 0.5 0.9 -0.7 0.2 0.5 0.4 -0.8
Forced expiratory volume in 1-second (FEV1) 1.0 3.4 7.2 -1.8 2.7 -2.3 0.5 0.3 0.2 1.9 0.0 1.6 -1.6 2.4 1.5 2.7 2.3 2.3 2.6 -0.3 1.6 2.5 1.0 1.9
Pulse rate 0.4 0.7 2.0 -0.7 0.9 -0.6 -0.4 -0.4 1.4 1.3 0.0 0.1 -1.2 0.5 1.1 1.1 1.0 1.0 0.9 0.0 0.8 0.9 0.8 0.8
Happiness 1.8 2.2 6.7 -0.9 2.3 -1.4 2.0 1.8 1.1 0.5 0.0 2.6 -0.8 0.9 0.6 1.5 1.3 1.5 1.8 -0.4 -0.4 2.4 0.6 2.3
Noisy workplace 1.1 1.3 6.6 1.6 -1.8 0.4 -0.2 -0.2 -0.6 -1.2 0.0 -0.5 0.8 -0.5 -0.9 -0.8 -1.4 -1.4 -1.1 -0.8 -1.3 -1.6 -1.1 -2.6
Qualifications: A levels/AS levels or equivalent 0.2 0.4 3.1 0.6 0.4 -0.4 0.1 0.1 0.1 0.5 0.0 1.1 -0.9 -0.2 0.4 0.0 0.4 0.3 0.3 1.8 0.0 0.3 -0.3 0.7
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 1.2 -0.1 0.0 -0.6 0.1 0.3 0.3 -0.5 0.0 -0.2 -1.1 0.7 -0.2 0.2 0.3 0.1 0.3 0.1 0.3 0.0 0.0 -0.1
Mouth/teeth dental problems: Dentures 0.2 0.4 3.8 -0.8 -0.1 0.7 -0.3 -0.4 0.9 0.2 0.0 -1.9 0.5 0.2 0.7 -0.2 -0.2 0.1 -0.2 -0.4 0.4 0.1 0.9 -0.0
Asthma 0.9 1.7 4.6 2.0 -1.1 1.4 -1.2 -1.3 -0.7 0.6 0.0 1.5 -0.2 -1.7 -0.3 -1.8 -1.3 -1.3 -1.6 2.1 -1.6 -1.1 -1.5 -0.8
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 2.0 0.6 -0.7 -0.1 -0.9 -1.0 -0.2 -0.6 0.0 -0.5 -1.3 0.2 0.4 -0.1 -0.6 -0.5 -0.3 -1.4 0.3 -0.7 -0.5 -1.1
Medication: Cholesterol lowering 0.6 1.0 2.9 1.0 -1.0 1.6 -0.9 -1.0 -0.6 -1.7 0.0 -0.7 0.6 -1.6 0.0 -1.7 -0.9 -1.0 -1.3 -0.5 -0.6 -0.8 -0.2 0.2
Depression (self-reported) 0.6 0.8 1.8 0.5 -1.3 1.3 -0.7 -0.7 -0.4 -0.1 0.0 -1.0 0.1 -1.1 0.2 -1.3 -1.1 -1.1 -1.3 -0.2 -1.0 -1.2 -0.2 -0.5
Medication: Lansoprazole 1.5 1.7 5.7 -0.3 -0.1 2.4 -2.2 -2.4 1.1 1.5 0.0 -0.4 -0.5 -1.9 1.0 -1.8 -0.0 -0.2 -1.3 2.0 0.1 -0.1 0.9 1.1
Prospective memory result 0.2 0.3 1.2 -1.1 0.1 -0.0 -0.5 -0.4 -0.1 -0.6 0.0 -0.9 0.3 0.1 0.3 0.3 0.3 0.4 0.2 -0.8 0.7 0.1 0.7 0.2
Lung cancer (father) 1.3 1.5 4.8 -0.5 1.8 -1.5 0.8 0.7 0.3 0.2 0.0 2.2 0.4 1.8 0.7 1.7 1.4 1.7 1.7 -0.4 0.5 1.8 0.3 1.5
Illnesses of mother 0.3 0.4 2.1 -0.9 0.3 0.0 -1.4 -1.4 0.1 0.2 0.0 0.3 -1.1 0.4 0.8 0.1 0.4 0.5 0.3 -0.3 0.6 0.4 0.5 0.7
Forced expiratory volume in 1-second (FEV1), Best measure 2.3 7.3 15.2 -2.5 3.9 -3.5 0.8 0.8 1.3 1.9 0.0 2.1 -2.6 3.8 1.8 3.9 3.4 3.5 3.8 -0.8 2.5 3.6 1.6 2.9
Pulse wave Arterial Stiffness index 0.6 0.7 2.9 0.8 -1.2 0.1 0.5 0.6 -0.6 -0.8 0.0 -0.9 0.1 0.2 -1.3 -0.4 -1.0 -1.1 -0.6 0.6 -0.5 -1.3 -0.9 -1.7
Impedance of arm (left) 0.4 1.6 4.6 -0.8 1.7 -1.6 0.0 0.2 0.3 -1.0 0.0 1.3 -1.1 1.7 0.4 1.9 1.6 1.7 1.7 -2.1 0.0 1.7 0.8 0.9
Arm fat mass (right) 0.1 0.4 2.2 0.3 0.9 -0.3 -0.1 -0.1 1.1 0.7 0.0 -0.1 0.2 0.2 0.4 0.1 0.7 0.5 0.6 0.7 0.4 0.9 0.4 1.5
Trunk predicted mass 0.1 0.5 3.4 0.7 0.5 -0.8 0.8 0.6 -0.3 1.0 0.0 1.4 0.4 0.3 0.0 0.3 0.1 0.0 0.4 1.9 0.2 0.3 -1.0 0.5
Standing height 0.2 1.6 12.9 0.8 1.5 -1.9 1.1 1.0 -1.2 0.1 0.0 3.6 0.6 1.3 0.1 1.3 1.0 0.9 1.3 0.9 -0.4 1.2 -1.1 0.9
Length of working week for main job 1.5 1.7 4.1 1.1 -1.4 1.9 -1.9 -1.7 0.1 -0.3 0.0 -0.4 0.9 -1.9 -0.0 -2.0 -1.2 -1.4 -1.8 0.8 -1.6 -1.3 -0.4 -0.9
Exposure to tobacco smoke at home 2.7 3.0 7.1 0.4 -2.3 1.6 1.0 1.2 -2.3 -2.0 0.0 -1.7 2.7 -1.2 -2.2 -1.9 -2.2 -2.1 -2.0 -0.6 -1.1 -2.2 -0.7 -1.9
Breastfed as a baby 0.5 0.6 3.9 0.7 -0.6 0.0 0.5 0.6 -2.0 0.7 0.0 0.0 0.8 -0.7 -0.7 -0.6 -0.7 -0.9 -0.4 1.7 -0.1 -0.7 -1.1 -0.2
Tense / ‘highly strung’ 1.3 2.1 8.8 -0.8 -0.6 1.8 -3.0 -3.0 1.4 0.3 0.0 -2.4 -2.2 -0.9 2.0 -1.1 0.0 -0.1 -0.9 -1.2 0.2 -0.3 1.5 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.7 2.6 6.3 -2.4 1.2 0.1 -0.8 -0.9 2.4 2.5 0.0 -1.9 -2.2 0.6 2.2 0.8 1.4 1.3 0.9 -1.6 1.7 1.4 2.4 1.6
Hair/balding pattern: Pattern 4 0.9 2.1 6.5 1.9 -1.9 -0.5 0.2 0.2 -2.6 -1.8 0.0 -0.6 1.2 0.5 -1.2 -0.6 -1.7 -1.6 -0.9 1.1 -0.5 -2.1 -2.3 -2.3
Birth weight of first child 0.8 1.5 10.1 0.4 1.4 -1.0 1.2 1.0 0.2 2.2 0.0 3.2 -0.6 0.3 -0.1 0.8 0.6 0.6 0.9 2.2 -0.4 1.2 -0.7 0.7
Peak expiratory flow (PEF) 2.4 5.5 12.3 -2.2 3.5 -2.6 0.3 0.2 1.9 0.2 0.0 1.5 -1.3 2.8 1.7 3.2 3.2 3.1 3.2 -2.3 1.6 3.5 2.2 2.7
Pulse wave reflection index 0.3 0.4 2.0 -0.1 -0.4 -0.3 1.1 1.0 -0.2 -0.8 0.0 -1.4 0.3 0.7 -0.9 0.2 -0.2 -0.4 0.2 -0.2 0.3 -0.4 0.0 -0.8
Ever highly irritable/argumentative for 2 days 1.0 1.2 4.1 -1.7 1.1 0.6 -0.0 0.1 1.9 1.3 0.0 -1.7 0.1 0.2 1.2 0.6 1.1 1.3 0.6 -1.0 0.7 1.3 2.0 0.7
Loud music exposure frequency 4.7 5.2 11.6 2.8 -3.0 0.3 1.0 1.0 -3.0 -3.4 0.0 -0.6 2.8 -0.4 -2.7 -1.5 -2.9 -2.9 -1.8 -0.3 -1.5 -3.0 -2.9 -3.2
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 2.1 -0.6 1.0 -1.1 1.0 1.0 0.4 0.2 0.0 -0.4 -0.9 0.7 0.6 1.1 1.0 1.1 1.2 -0.5 1.4 0.9 0.6 1.3
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 6.1 -0.5 1.2 -0.3 1.3 1.3 0.6 1.2 0.0 2.5 -1.1 0.1 -0.2 0.7 0.5 0.7 0.7 -0.5 -0.2 1.3 0.2 1.0
Blood clot in the leg (DVT) 0.8 1.0 6.1 -0.7 -0.9 1.3 -1.4 -1.4 -0.1 -0.7 0.0 -2.5 -1.5 -0.3 0.8 -0.9 -0.6 -0.4 -0.9 -1.1 0.2 -0.7 0.8 -0.7
Medication: Paracetamol 0.8 1.3 7.3 0.3 -0.2 0.6 -2.7 -2.7 1.4 1.7 0.0 -0.3 -1.9 -0.4 1.6 -0.2 0.1 0.2 -0.3 -0.7 0.2 -0.0 0.4 -0.1
Headache pain in last month 0.6 1.0 5.0 -1.2 -0.2 0.9 -1.5 -1.5 1.0 0.9 0.0 -2.2 -1.4 -0.3 1.2 -0.3 0.1 0.1 -0.4 -0.4 0.8 -0.2 1.3 -0.3
Medication for cholesterol, blood pressure or diabetes 0.7 1.2 4.1 -1.4 1.1 -1.6 -0.0 0.1 0.6 1.8 0.0 0.2 -0.4 2.0 0.6 1.7 1.1 1.3 1.5 -0.2 1.3 1.0 0.6 0.4
Glaucoma (self-reported) 0.3 0.4 1.0 -0.4 0.8 -0.9 0.0 0.0 0.7 0.6 0.0 -0.1 -0.3 0.9 0.5 1.0 1.0 0.7 0.9 -0.3 1.0 0.7 0.3 0.2
Gout (self-reported) 1.1 1.5 4.0 -0.3 1.6 -1.3 1.7 1.8 2.0 0.6 0.0 0.4 0.1 1.1 0.3 1.5 1.4 1.3 1.5 0.0 1.2 1.5 0.7 1.4
Hypothyroidism/myxoedema (self-reported) 1.2 2.3 5.3 0.7 -2.1 1.9 -1.8 -1.7 -0.9 -1.0 0.0 -2.1 1.1 -2.0 -0.7 -2.3 -1.6 -1.8 -2.1 1.1 -0.1 -2.1 -0.5 -1.0
Medication: Amlodipine 0.3 0.5 1.6 0.3 0.1 -1.3 0.7 1.0 -0.4 -0.7 0.0 0.7 -0.7 1.0 -1.0 0.6 0.2 0.0 0.6 0.7 1.2 -0.1 -0.8 0.2
Medication: Ventolin 100micrograms inhaler 0.9 1.2 3.2 1.7 -1.5 0.7 -0.4 -0.2 -0.9 -0.6 0.0 0.3 0.5 -0.7 -0.8 -1.1 -1.3 -1.1 -1.2 1.1 -1.2 -1.5 -1.5 -1.8
Birth weight 0.3 0.7 1.5 -0.9 1.2 -0.6 -0.2 -0.0 0.8 0.5 0.0 0.2 -0.4 0.8 0.7 0.9 1.1 1.2 0.9 -0.8 0.7 1.2 0.9 1.1
Chronic bronchitis/emphysema (mother) 3.0 3.5 11.9 -3.0 1.6 0.1 -1.6 -1.4 3.0 1.5 0.0 -2.3 -1.8 0.9 2.0 1.0 2.0 2.1 1.2 -1.5 1.4 1.7 3.4 1.6
High blood pressure (siblings) 0.9 1.2 8.2 0.9 -0.3 0.1 2.8 2.9 -0.1 -0.5 0.0 -0.5 1.9 0.3 -1.8 -0.2 -0.5 -0.7 -0.3 0.5 -0.3 -0.4 -0.6 -0.4
Forced vital capacity (FVC), Best measure 1.2 4.3 11.8 -0.8 2.7 -3.4 1.6 1.6 0.1 1.2 0.0 3.1 -2.1 3.4 0.6 3.2 2.2 2.4 3.0 -0.3 0.9 2.5 -0.1 1.4
Body fat percentage 0.2 0.7 3.4 -0.2 1.2 -0.0 -0.1 -0.1 1.7 0.3 0.0 -0.4 0.4 0.1 0.7 0.1 1.0 0.9 0.7 0.3 0.5 1.3 1.1 1.8
Leg fat percentage (right) 0.3 0.9 4.1 -0.5 0.8 0.9 -1.0 -1.0 2.0 0.7 0.0 -1.2 0.5 -0.4 0.9 -0.5 0.7 0.6 0.1 0.4 0.6 1.0 1.4 1.9
Arm fat-free mass (right) 0.1 0.5 2.7 -0.1 0.8 -0.2 0.4 0.3 0.1 1.2 0.0 0.6 0.8 -0.0 0.5 -0.0 0.4 0.3 0.3 1.6 0.8 0.6 -0.1 1.4
Exposure to tobacco smoke outside home 1.0 1.4 5.0 0.8 -1.5 0.5 -0.7 -0.7 -1.7 -2.2 0.0 -0.7 1.0 -0.6 -1.1 -1.3 -1.4 -1.4 -1.1 -0.4 -1.4 -1.4 -0.8 -1.4
Comparative body size at age 10 0.0 0.1 0.5 0.1 -0.1 -0.0 -0.1 -0.1 -0.1 -0.5 0.0 0.1 0.1 -0.3 -0.4 -0.3 -0.1 -0.1 -0.1 0.7 -0.2 -0.2 -0.2 0.3
Number of full brothers 1.5 1.8 6.8 -2.6 1.3 -0.2 0.2 0.0 1.5 1.6 0.0 -1.7 -0.9 1.2 1.3 1.4 1.3 1.4 1.1 -1.5 1.5 1.4 2.2 0.7
Worry too long after embarrassment 1.9 3.2 8.7 -2.9 1.7 -0.2 -1.1 -1.3 1.6 0.1 0.0 -1.5 -2.3 0.8 2.5 1.5 1.6 1.9 1.3 -2.5 1.9 1.9 2.7 2.0
Seen a psychiatrist for nerves, anxiety, tension or depression 1.3 1.7 3.6 1.2 -1.8 1.6 0.0 -0.0 -0.9 0.6 0.0 -0.8 0.8 -1.0 -0.5 -1.9 -1.8 -1.8 -1.8 1.8 -1.2 -1.8 -1.2 -1.2
Wheeze or whistling in the chest in last year 1.6 2.9 11.8 -0.1 -1.2 3.4 -2.3 -2.5 0.5 1.5 0.0 -1.3 -0.4 -2.9 0.9 -2.6 -1.1 -1.4 -2.3 1.9 -1.0 -1.1 0.8 -0.5
Number of children fathered 1.2 1.4 7.5 -1.8 -0.1 1.0 -1.4 -1.5 0.2 2.1 0.0 -2.7 0.6 -0.6 1.6 -0.1 0.2 0.3 -0.3 0.8 1.6 -0.2 1.5 0.0
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.2 4.6 1.2 -1.5 -0.3 -1.6 -1.4 -1.8 -2.1 0.0 -0.4 -0.2 0.3 -0.7 -0.8 -0.9 -1.0 -0.6 -1.0 -0.4 -1.4 -1.3 -0.6
Age at first live birth 0.6 1.1 7.5 0.4 1.1 -1.5 -0.6 -0.5 -0.8 0.1 0.0 2.7 -0.2 0.8 1.2 1.2 1.1 1.1 1.2 0.7 0.4 1.0 -0.5 1.0
Pulse wave peak to peak time 0.6 0.7 3.0 -0.9 1.2 -0.1 -0.5 -0.5 0.5 0.9 0.0 1.1 0.0 -0.2 1.3 0.4 1.0 1.1 0.6 -0.4 0.6 1.2 0.8 1.7
Health satisfaction 0.2 0.3 1.6 0.0 0.1 0.1 1.3 1.2 0.2 0.1 0.0 0.4 0.7 0.1 -0.6 0.1 -0.3 -0.3 -0.0 -0.7 -0.7 0.3 -0.2 0.1
Shortness of breath walking on level ground 2.1 2.5 9.7 -2.3 1.4 -0.5 -0.7 -0.5 2.2 1.0 0.0 -1.8 -0.5 1.2 1.1 0.9 1.8 1.5 1.4 -0.9 3.1 1.5 2.3 2.5
Qualifications: College or University degree 0.5 1.4 4.9 1.4 0.6 -2.1 1.8 1.9 -0.6 -0.9 0.0 2.2 0.6 1.2 -0.5 1.6 0.5 0.8 1.3 0.5 -0.9 0.4 -1.3 -0.7
Eye problems/disorders: None of the above 0.3 0.4 2.7 -0.5 -0.0 1.2 0.2 0.1 0.3 -0.2 0.0 -1.7 0.8 -0.0 0.2 -0.5 0.1 0.1 -0.4 -0.8 -0.2 0.2 1.1 0.3
Mouth/teeth dental problems: Loose teeth 1.3 1.5 4.1 1.0 -1.7 1.2 0.1 0.1 -0.7 -0.3 0.0 -1.0 -0.1 -1.9 -1.0 -1.4 -1.6 -1.7 -1.6 0.8 -1.6 -1.7 -0.8 -2.0
Emphysema/chronic bronchitis 1.3 1.5 3.6 0.1 -1.5 1.8 0.7 0.7 -0.5 -0.6 0.0 -0.6 1.8 -1.3 -1.4 -1.9 -1.6 -1.6 -1.8 0.9 -0.9 -1.5 -0.5 -0.8
Medication for pain relief, constipation, heartburn 1.1 1.8 5.0 -0.5 1.4 -2.2 2.2 2.2 -1.0 -1.1 0.0 1.5 1.0 2.0 -0.8 1.7 1.2 1.1 1.8 1.0 0.2 1.1 -0.2 0.8
Neck or shoulder pain in last month 0.3 0.4 2.1 0.1 -0.7 0.1 -0.8 -0.8 0.2 -0.9 0.0 -1.1 0.4 0.2 0.8 -0.1 -0.2 -0.2 -0.2 -1.4 -0.2 -0.6 0.2 -1.1
Medication: Blood pressure 1.7 2.9 5.3 2.0 -1.9 1.8 0.7 0.7 -1.9 -2.2 0.0 0.5 1.2 -2.2 -2.0 -2.3 -2.0 -2.2 -2.2 0.6 -2.1 -1.8 -1.7 -1.2
Angina (self-reported) 0.9 1.2 10.7 -0.9 -1.2 1.2 -0.2 -0.1 -0.4 -0.8 0.0 -3.3 1.2 -0.4 -0.3 -0.8 -0.8 -0.8 -1.1 -1.0 0.5 -1.2 0.7 -0.9
Migraine (self-reported) 1.0 1.3 3.0 -1.3 0.8 -0.1 -1.5 -1.6 1.2 0.9 0.0 -1.4 -1.5 0.6 1.7 0.8 1.1 1.2 0.7 -0.8 1.3 0.9 1.6 0.6
Medication: Ibuprofen 0.3 0.4 2.5 0.4 -0.5 -0.6 0.2 0.1 -0.1 -0.8 0.0 -0.8 -1.2 0.7 0.3 0.4 -0.3 -0.3 0.1 -1.6 0.4 -0.5 -0.3 -1.2
Medication: Allopurinol 0.4 0.6 3.0 -0.1 0.6 0.1 1.2 1.3 1.7 1.4 0.0 -0.6 0.2 -0.1 0.3 0.3 0.5 0.5 0.2 1.0 1.0 0.5 0.5 0.4
Medication: Omeprazole 0.5 0.6 1.5 0.6 -1.0 1.2 -0.8 -0.8 0.4 0.1 0.0 -0.9 -0.4 -1.0 -0.1 -1.0 -0.9 -0.8 -1.2 -0.7 -0.6 -1.0 -0.2 -0.9
Medication: Seretide 50 evohaler 2.9 3.4 7.0 2.1 -1.9 1.3 1.6 1.6 -2.1 -0.5 0.0 1.2 1.9 -1.8 -2.0 -1.8 -2.2 -2.2 -2.0 1.5 -2.6 -2.0 -2.1 -2.2
Mean time to correctly identify matches 3.9 7.4 18.7 1.8 -3.3 4.3 -1.4 -1.4 -1.8 1.3 0.0 -1.3 2.0 -4.3 -0.8 -4.0 -3.0 -3.0 -4.1 2.9 -3.1 -3.2 -1.4 -2.8
Heart disease (mother) 3.3 4.0 8.6 2.3 -2.4 2.0 0.6 0.5 -2.3 -1.8 0.0 0.2 1.4 -2.2 -1.9 -2.6 -2.5 -2.5 -2.7 1.1 -2.9 -2.4 -2.0 -2.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.0 1.1 3.8 0.1 -1.1 1.9 -0.5 -0.7 -0.7 0.6 0.0 -1.5 1.2 -1.5 -0.1 -1.4 -1.1 -1.3 -1.5 1.3 0.1 -1.1 0.0 -0.9
Whole body fat mass 0.1 0.5 2.8 0.2 1.0 0.0 0.0 -0.0 1.4 0.6 0.0 -0.1 0.6 0.1 0.6 -0.1 0.7 0.6 0.5 0.9 0.4 1.0 0.6 1.7
Leg fat mass (right) 0.2 0.9 4.5 -0.3 1.1 0.4 -0.5 -0.6 1.8 1.2 0.0 -0.5 0.4 -0.1 1.0 -0.3 0.8 0.8 0.4 0.8 0.6 1.2 1.1 2.1
Arm predicted mass (right) 0.1 0.5 2.3 -0.1 0.8 -0.4 0.4 0.2 0.2 1.1 0.0 0.8 0.6 0.3 0.6 0.1 0.5 0.4 0.5 1.5 0.9 0.7 -0.1 1.4
Pulse rate, automated reading 0.3 1.1 4.3 0.2 0.2 -2.1 1.9 1.8 -0.5 -0.4 0.0 0.7 0.5 1.6 -0.4 1.7 0.5 0.6 1.3 -0.8 0.2 0.2 -0.6 -0.9
Alcohol intake frequency. 1.7 3.9 8.0 -2.8 2.1 -0.9 -0.9 -0.9 2.6 1.3 0.0 -1.4 -1.2 2.2 2.2 1.9 2.2 2.6 1.9 -2.1 2.0 2.3 2.8 2.0
Comparative height size at age 10 0.1 0.4 1.6 0.6 -0.1 0.2 0.4 0.4 -0.6 -0.2 0.0 1.3 1.1 -0.5 -0.8 -0.5 -0.3 -0.5 -0.4 1.1 -0.7 -0.2 -0.7 0.2
Number of full sisters 2.7 3.3 8.6 1.8 -2.5 0.9 -0.0 0.0 -2.8 -2.2 0.0 -1.0 1.5 -0.8 -1.8 -1.7 -2.3 -2.4 -1.9 0.3 -1.6 -2.5 -2.2 -2.9
Suffer from ‘nerves’ 3.2 5.1 11.8 -3.4 2.3 -0.2 -1.4 -1.6 2.6 2.0 0.0 -2.1 -2.2 1.5 3.3 1.6 2.5 2.5 1.7 -1.3 2.7 2.4 3.4 2.7
Overall health rating 0.7 1.5 4.8 -1.5 0.1 1.8 -2.0 -2.2 1.6 1.9 0.0 -1.7 0.7 -1.0 1.7 -0.7 0.0 0.1 -0.7 -0.7 -0.0 0.3 1.5 0.4
Chest pain or discomfort 1.7 2.4 15.7 -1.8 -0.6 1.6 -2.6 -2.8 0.6 0.9 0.0 -4.0 -0.7 -0.4 2.1 -0.7 0.1 -0.0 -0.7 -0.6 1.4 -0.5 2.0 -0.2
Had major operations 0.3 0.4 2.3 -0.5 0.3 -0.3 0.5 0.4 1.2 -0.0 0.0 -1.2 0.3 0.6 0.2 0.8 0.3 0.5 0.4 -1.5 0.7 0.3 0.6 -0.2
Age at last live birth 0.6 0.8 5.3 0.6 0.7 -1.7 0.3 0.4 -0.4 -0.2 0.0 2.3 -0.6 1.4 0.4 1.3 0.7 0.8 1.2 0.1 0.2 0.6 -0.6 0.3
Family relationship satisfaction 0.2 0.2 1.1 0.1 -0.1 0.4 0.6 0.6 -0.0 -0.0 0.0 1.0 0.2 -0.5 -0.5 -0.5 -0.6 -0.4 -0.4 -0.4 -0.8 -0.0 -0.3 0.0
Leg pain on walking 0.7 0.9 3.0 -1.2 0.8 0.6 -1.7 -1.7 0.5 1.4 0.0 0.6 -1.1 -0.5 1.0 -0.1 0.8 0.6 0.2 0.3 0.5 0.9 1.0 1.1
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.9 -0.1 -0.1 0.1 0.9 1.0 0.0 -0.4 0.0 -0.1 0.9 -0.1 -0.9 -0.3 -0.3 -0.4 -0.1 0.2 0.2 -0.1 -0.2 0.2
Commuting to job workplace: Car/motor vehicle 1.9 2.2 5.6 0.3 -1.8 2.3 -1.0 -0.9 -0.9 -0.9 0.0 -1.2 1.9 -2.4 -1.4 -2.1 -1.9 -1.9 -2.2 -0.0 -0.8 -1.7 -0.6 -1.2
Illness, injury, bereavement, stress in last 2 years 1.5 1.9 5.2 -1.1 1.9 0.3 -0.9 -1.1 2.1 1.4 0.0 1.0 -1.2 -0.0 1.9 0.6 1.7 1.8 0.9 0.6 1.0 1.9 1.7 2.3
Medication: Aspirin 1.7 2.2 6.5 0.2 -2.0 2.6 -0.3 -0.1 -0.7 -1.0 0.0 -2.4 1.4 -2.3 -0.7 -2.1 -1.8 -1.7 -2.3 -0.3 -0.6 -1.9 0.0 -1.2
Supplements: Vitamin C 0.5 0.5 2.6 0.1 0.5 -1.5 0.5 0.6 -0.2 -0.2 0.0 0.5 -0.5 1.6 0.2 1.1 0.5 0.5 1.1 -0.8 0.8 0.5 -0.4 0.4
Knee pain experienced in last month 0.7 1.1 3.1 -0.5 1.1 -1.7 1.0 0.9 0.0 -0.5 0.0 1.3 -0.0 1.8 -0.1 1.6 0.9 0.9 1.5 -1.7 0.7 1.1 0.1 0.7
Hypertension (Self-reported) 1.5 4.2 9.3 2.0 -2.1 1.7 2.2 2.3 -1.6 -1.9 0.0 0.9 1.8 -2.2 -3.0 -2.5 -2.6 -2.6 -2.3 1.1 -2.2 -2.0 -2.2 -1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.1 1.3 6.8 -1.2 0.3 1.3 -2.6 -2.6 1.5 0.6 0.0 -1.0 -1.1 -1.0 1.2 -0.5 0.5 0.5 -0.4 -0.4 0.4 0.4 1.5 0.6
Illnesses of father: Heart disease 1.3 1.8 3.9 -1.7 1.9 -1.0 0.0 -0.1 1.1 0.8 0.0 0.1 -1.2 1.2 1.4 1.8 1.7 1.7 1.6 -1.1 1.2 2.0 1.5 1.9
Illnesses of siblings: Diabetes 4.1 5.1 9.2 1.8 -2.8 1.8 1.5 1.7 -2.6 -1.4 0.0 -0.4 2.0 -2.1 -3.0 -2.5 -3.0 -3.0 -2.6 2.2 -1.8 -3.0 -2.4 -2.5
Smoking status: Previous 7.6 11.3 22.4 4.0 -4.2 2.8 1.2 1.2 -3.0 -1.7 0.0 0.1 3.6 -3.6 -3.8 -4.0 -4.4 -4.7 -4.2 2.0 -4.0 -4.3 -3.6 -3.8
Forced expiratory volume in 1-second (FEV1), predicted 1.8 3.7 9.7 -0.8 2.7 -3.1 0.8 0.8 0.7 -0.2 0.0 2.7 -1.4 2.7 0.7 2.9 2.3 2.2 2.9 -1.3 1.2 2.5 0.4 2.0
Whole body fat-free mass 0.1 0.7 2.7 0.5 1.0 -1.0 0.8 0.7 0.1 1.0 0.0 1.6 0.3 0.6 0.2 0.5 0.6 0.5 0.8 1.6 0.5 0.8 -0.6 1.2
Leg fat-free mass (right) 0.2 1.0 3.5 0.5 1.4 -1.4 0.5 0.4 0.2 0.8 0.0 1.9 -0.1 1.0 0.4 0.9 1.0 0.9 1.2 1.2 0.7 1.2 -0.4 1.7
Arm fat percentage (left) 0.2 0.6 3.1 -0.2 1.3 -0.3 -0.1 -0.1 1.4 0.4 0.0 -0.5 -0.1 0.4 0.7 0.4 1.0 0.9 0.8 0.2 0.6 1.3 0.9 1.7
Average weekly red wine intake 1.1 1.6 4.3 2.0 -0.9 -0.1 1.7 1.6 -1.7 -1.1 0.0 0.9 1.8 -0.5 -1.3 -0.4 -1.3 -1.2 -0.8 0.1 -1.3 -1.0 -2.1 -1.3
Handedness (chirality/laterality): Left-handed 1.1 1.4 4.6 0.8 -0.9 1.7 -0.5 -0.7 -0.9 0.1 0.0 1.1 0.9 -2.1 -0.4 -2.0 -1.4 -1.2 -1.5 1.8 -1.2 -0.9 -0.9 0.1
Mood swings 2.6 4.7 10.3 -2.4 2.0 -1.2 -2.7 -2.6 2.4 1.0 0.0 -0.8 -3.2 1.6 2.9 1.9 2.3 2.3 2.0 -2.6 2.3 2.2 2.3 2.4
Loneliness, isolation 2.2 3.0 8.0 -2.6 1.1 -0.2 -1.4 -1.4 2.0 0.7 0.0 -2.3 -1.1 0.9 2.7 1.3 1.6 1.8 1.2 -2.7 2.3 1.2 2.8 1.0
Long-standing illness, disability or infirmity 7.0 10.7 24.1 2.4 -4.7 4.5 -0.8 -0.8 -2.4 -1.2 0.0 -2.7 2.6 -4.3 -2.0 -4.8 -4.3 -4.3 -4.9 2.1 -2.4 -4.6 -2.1 -3.5
Ever had bowel cancer screening 0.3 0.4 1.1 -0.4 0.5 -0.3 0.2 0.2 0.9 1.1 0.0 -0.5 -0.2 0.7 0.9 0.6 0.7 0.7 0.5 -0.3 0.9 0.5 0.6 0.5
Diabetes diagnosed by doctor 2.8 4.7 9.2 1.7 -2.4 2.6 0.9 0.7 -1.9 -1.0 0.0 -0.4 3.0 -3.0 -2.1 -3.0 -2.8 -3.0 -2.9 2.1 -1.8 -2.4 -1.7 -1.6
Ever had stillbirth, spontaneous miscarriage or termination 1.1 1.2 3.4 0.4 -1.8 1.1 -1.4 -1.2 -0.3 -0.7 0.0 -1.5 -0.5 -0.8 -0.4 -1.3 -1.3 -1.2 -1.3 -0.2 -0.8 -1.7 -0.1 -1.8
Friendships satisfaction 0.7 0.9 4.6 -0.4 0.7 -0.9 2.1 2.0 -0.4 0.3 0.0 1.4 0.4 0.8 -0.2 1.0 0.1 0.4 0.7 -1.7 -0.7 0.8 -0.2 0.0
Qualifications: nursing, teaching 0.3 0.5 5.6 0.3 -0.1 0.5 0.4 0.4 0.4 0.8 0.0 0.7 0.0 -1.2 -0.2 -0.4 -0.4 -0.2 -0.4 2.4 -0.9 -0.2 -0.3 -0.7
Commuting to job workplace: Walk 0.2 0.2 1.5 -0.3 -0.0 -0.3 0.3 0.5 0.2 -1.2 0.0 -0.4 -0.7 0.6 0.0 0.2 0.2 0.2 0.2 -1.0 0.3 0.0 0.4 0.2
Eye problems/disorders: Cataract 1.0 1.1 4.4 1.7 -0.7 -1.0 0.7 0.8 -1.1 -0.6 0.0 2.0 -0.4 -0.3 -1.5 -0.0 -0.9 -0.8 -0.1 0.7 -1.0 -0.9 -2.1 -1.2
Mouth/teeth dental problems: Mouth ulcers 3.0 4.8 12.2 -2.7 2.5 -0.3 -1.7 -1.9 2.7 2.7 0.0 0.2 -2.6 1.2 3.5 1.5 2.5 2.6 1.8 -1.0 1.7 2.6 2.9 2.9
Medication for cholesterol 1.3 1.9 4.2 -0.3 1.9 -1.7 0.7 0.6 1.5 1.5 0.0 2.0 -2.1 1.4 1.0 2.0 1.6 1.7 1.8 -0.4 -0.2 1.9 0.5 0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 1.7 -0.5 0.0 0.2 0.5 0.3 -0.3 -0.7 0.0 -0.8 -1.3 -0.5 0.2 -0.0 -0.1 -0.2 -0.0 -1.1 0.4 0.0 0.4 0.0
Back pain experienced in last month 1.1 1.6 9.3 -0.9 -0.7 1.4 -2.9 -3.1 0.6 0.3 0.0 -2.1 -0.0 -0.9 1.5 -0.9 -0.0 -0.3 -0.8 -1.2 0.8 -0.5 1.2 0.1
Mineral and other dietary supplements 1.4 1.8 5.7 0.4 -1.4 2.3 -0.0 0.0 -0.3 -0.5 0.0 -0.9 0.9 -2.4 -0.9 -2.2 -1.7 -1.7 -2.0 0.9 -1.9 -1.4 -0.3 -1.2
Breast cancer (self-reported) 2.6 3.1 10.9 3.3 -1.1 -0.7 1.7 1.9 -1.7 -0.7 0.0 2.4 0.9 0.2 -2.6 -1.0 -1.3 -1.6 -0.7 2.6 -2.0 -1.4 -3.1 -0.9
Asthma (self-reported) 1.0 2.0 4.9 1.8 -1.2 1.8 -1.6 -1.7 -0.6 0.9 0.0 1.2 -0.5 -2.0 -0.1 -2.0 -1.3 -1.3 -1.8 2.2 -1.5 -1.1 -1.2 -0.7
Osteoporosis (self-reported) 0.7 0.9 8.8 -1.1 -0.6 0.4 0.3 0.3 0.1 -0.8 0.0 -3.0 0.5 0.1 0.4 -0.1 -0.3 -0.2 -0.3 -1.9 1.0 -0.5 1.1 -0.2
Osteoarthritis (self-reported) 0.3 0.4 3.6 -0.2 0.3 0.9 -0.3 -0.5 0.1 1.9 0.0 0.6 0.6 -1.0 0.4 -0.4 -0.2 -0.0 -0.5 0.2 -0.9 0.3 0.2 0.1
Medication: Aspirin 1.6 2.0 4.5 0.6 -2.0 2.1 0.4 0.5 -0.8 -1.3 0.0 -1.9 1.7 -1.8 -1.2 -1.8 -1.8 -1.7 -2.1 -0.6 -0.5 -1.9 -0.4 -1.4
Medication: Gliclazide 1.5 1.7 3.6 0.7 -1.7 1.0 0.9 0.9 -1.4 -0.4 0.0 -0.2 1.9 -0.9 -1.6 -1.4 -1.9 -1.7 -1.5 1.6 -0.7 -1.9 -1.3 -1.5
Illnesses of father: None of the above (group 1) 0.9 1.1 3.3 -0.8 1.2 -1.8 0.1 0.2 0.2 0.2 0.0 0.2 -0.5 1.6 0.9 1.7 1.3 1.4 1.7 -0.9 1.2 1.2 0.5 0.6
Smoking status: Current 0.5 0.7 3.7 -0.7 0.3 0.7 -0.9 -1.1 1.4 -0.8 0.0 -0.7 -1.4 -0.1 1.0 -0.0 0.3 0.3 -0.0 -1.9 -0.7 0.5 1.4 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.8 1.7 5.3 -1.1 2.0 -1.1 1.1 1.1 0.3 2.3 0.0 1.6 -0.5 1.2 0.8 1.8 1.5 1.7 1.6 -0.3 0.5 1.9 0.6 1.2
Whole body water mass 0.1 0.6 2.6 0.5 0.9 -0.9 0.7 0.6 0.0 1.0 0.0 1.5 0.3 0.5 0.2 0.4 0.5 0.4 0.7 1.6 0.6 0.7 -0.6 1.2
Leg predicted mass (right) 0.2 1.0 3.5 0.4 1.4 -1.4 0.4 0.4 0.3 0.8 0.0 1.9 -0.2 1.0 0.5 0.9 1.1 1.0 1.3 1.1 0.8 1.3 -0.4 1.7
Arm fat mass (left) 0.1 0.6 3.0 -0.1 1.2 -0.5 0.0 0.0 1.2 0.7 0.0 -0.1 0.2 0.5 0.6 0.4 0.9 0.8 0.9 0.5 0.8 1.2 0.7 1.7
Number of self-reported non-cancer illnesses 4.0 6.9 15.9 2.2 -3.3 3.9 -1.0 -1.0 -1.5 -1.4 0.0 -1.6 2.0 -3.9 -1.2 -4.0 -3.2 -3.2 -4.0 2.0 -2.9 -3.2 -1.5 -2.7
Average weekly champagne plus white wine intake 3.9 5.3 11.4 2.8 -2.5 2.4 0.5 0.5 -2.9 -0.5 0.0 1.0 2.4 -2.9 -1.9 -3.0 -2.7 -2.7 -2.9 2.3 -3.4 -2.5 -2.4 -2.1
Miserableness 0.6 1.1 2.6 -0.7 1.4 -1.4 0.1 -0.1 1.3 0.3 0.0 0.2 -1.1 1.4 1.4 1.6 1.2 1.4 1.5 -0.8 0.5 1.4 0.6 0.9
Guilty feelings 1.2 1.9 5.6 -2.4 0.9 0.4 -1.0 -1.1 2.2 1.0 0.0 -2.1 -1.5 0.2 2.0 0.5 0.9 1.0 0.6 -1.2 1.4 1.0 2.3 1.2
Wears glasses or contact lenses 0.7 0.8 4.6 -0.2 -0.0 1.4 -0.4 -0.6 0.6 2.1 0.0 -1.4 0.3 -1.5 1.2 -0.7 -0.3 -0.2 -0.8 1.3 -0.6 -0.1 0.6 -0.3
Ever taken oral contraceptive pill 1.6 1.8 5.4 -0.0 1.1 -2.1 2.1 2.3 1.2 -0.0 0.0 0.9 1.2 1.8 -0.7 2.0 1.0 1.0 1.6 -2.0 0.7 1.0 0.1 0.1
Hearing aid user 0.4 0.4 1.5 0.0 0.6 -1.1 0.6 0.6 0.8 0.7 0.0 -0.3 0.6 1.2 0.1 1.0 0.6 0.5 0.9 -0.7 0.6 0.6 0.2 0.3
Mother’s age at death 0.2 0.3 1.3 0.3 0.0 -0.6 0.9 0.9 0.2 0.2 0.0 -0.3 1.2 0.5 0.0 0.5 0.2 0.2 0.4 1.0 0.2 -0.2 -0.1 -0.7
Financial situation satisfaction 0.5 0.7 2.8 -1.1 0.4 1.1 -0.1 -0.4 1.4 1.7 0.0 -0.6 -1.3 -0.8 0.9 -0.4 0.2 -0.0 -0.2 0.3 0.2 0.6 1.1 0.8
Tinnitus: Yes, now most or all of the time 0.6 0.7 3.3 0.3 1.0 -0.6 0.8 0.6 0.8 1.8 0.0 1.3 -0.9 0.7 0.8 0.9 0.7 1.0 0.8 0.5 0.1 1.0 0.2 0.2
Commuting to job workplace: Public transport 0.1 0.1 0.7 -0.0 -0.1 0.2 -0.1 -0.1 0.2 0.2 0.0 -0.8 -0.2 0.1 0.0 -0.3 0.1 -0.1 -0.1 0.5 0.2 -0.1 0.3 0.3
Eye problems/disorders: Glaucoma 1.3 1.5 3.8 -0.8 1.4 -1.8 0.7 0.8 1.1 0.8 0.0 -0.3 -0.1 1.7 0.9 2.0 1.7 1.5 1.8 -0.9 1.8 1.3 0.7 1.0
Medication: Blood pressure 1.3 2.4 5.6 0.3 -1.8 2.2 0.5 0.6 -1.1 -0.2 0.0 -1.0 1.6 -2.2 -1.8 -2.4 -2.1 -2.1 -2.2 2.1 -0.9 -1.8 -1.0 -1.0
Pain type(s) experienced in last month: Hip pain 0.4 0.5 2.5 -0.3 0.1 1.2 -0.8 -1.1 0.3 1.6 0.0 0.5 0.4 -0.9 1.2 -0.6 -0.1 -0.0 -0.6 0.5 -0.9 0.2 0.5 -0.4
Supplements: Fish oil (including cod liver oil) 0.5 0.6 1.7 -0.2 0.8 -1.0 -0.3 -0.5 -0.1 1.0 0.0 0.5 -0.9 1.2 1.1 1.1 1.1 1.0 1.0 0.1 1.3 0.7 0.3 0.6
High cholesterol (Self-reported) 0.5 0.9 2.4 -0.9 0.6 1.2 -1.4 -1.4 1.6 0.4 0.0 -0.7 -0.4 -1.0 1.2 -0.6 0.6 0.5 -0.2 -0.2 0.4 0.7 1.5 1.5
Medication: Bendroflumethiazide 1.5 2.3 5.1 1.4 -1.9 1.6 -0.8 -0.7 -2.1 -0.6 0.0 0.1 0.8 -1.8 -1.1 -2.2 -2.0 -2.1 -2.0 1.7 -1.1 -1.9 -1.7 -1.0
Medication: Paracetamol 1.2 1.8 11.2 0.3 -0.4 1.0 -3.3 -3.3 1.0 1.9 0.0 -0.6 -1.9 -0.5 1.8 -0.7 -0.0 0.0 -0.6 -0.7 0.4 -0.3 0.4 0.1
Medication: Lisinopril 0.7 0.9 2.6 1.6 -1.3 0.7 -0.8 -0.8 -0.7 -0.9 0.0 0.2 0.4 -1.2 -1.0 -1.4 -1.0 -1.4 -1.2 0.4 -0.2 -1.2 -1.0 -0.1
Medication: Atorvastatin 0.7 0.9 4.0 -0.5 -1.0 1.5 -0.9 -0.7 0.3 0.6 0.0 -2.0 0.3 -1.2 -0.1 -1.4 -0.7 -0.7 -1.1 1.4 0.9 -1.0 0.7 -0.0
Illnesses of father: High blood pressure 0.9 1.1 3.0 -1.0 0.9 -0.5 -0.0 0.1 1.7 0.9 0.0 -1.4 -0.3 1.0 1.2 1.3 1.2 1.2 1.0 -1.2 1.6 0.9 1.5 0.4
Alcohol drinker status: Never 0.9 1.1 2.4 0.8 -1.4 0.8 0.4 0.4 -1.2 -1.6 0.0 -0.4 0.7 -0.6 -1.6 -1.3 -1.3 -1.3 -1.2 0.9 -0.8 -1.4 -0.9 -0.9
Ever smoked 1.8 3.2 8.4 2.5 -2.3 1.4 0.2 0.1 -0.7 -2.1 0.0 0.1 1.1 -1.5 -1.9 -2.1 -2.2 -2.5 -2.2 -0.6 -2.9 -2.1 -1.6 -2.3
Basal metabolic rate 0.1 0.7 2.1 0.4 1.2 -1.0 0.5 0.4 0.3 1.0 0.0 1.4 0.2 0.7 0.3 0.6 0.8 0.6 1.0 1.4 0.6 1.0 -0.4 1.4
Leg fat percentage (left) 0.2 0.8 4.0 -0.4 1.0 0.5 -0.6 -0.7 2.0 0.9 0.0 -0.8 0.4 -0.1 1.1 -0.1 0.8 0.7 0.4 0.5 0.6 1.1 1.3 1.8
Arm fat-free mass (left) 0.1 0.5 2.0 0.3 0.8 -0.5 0.4 0.2 0.4 1.2 0.0 0.9 0.5 0.1 0.4 0.1 0.5 0.3 0.5 1.4 0.8 0.6 -0.3 1.4
Number of operations (self-reported) 0.6 1.0 6.1 -1.5 -0.2 0.5 -0.5 -0.4 0.9 -0.5 0.0 -2.4 -0.4 0.1 0.7 0.2 0.2 0.4 -0.1 -2.5 1.0 0.0 1.5 0.0
Average weekly beer plus cider intake 0.2 0.3 1.6 -1.2 0.0 0.2 0.6 0.5 0.7 0.4 0.0 -0.4 -0.5 -0.5 -0.7 0.3 0.1 -0.1 0.1 -1.2 0.9 0.1 0.6 -0.2
Irritability 5.1 8.6 26.7 -2.9 1.2 0.1 -5.2 -5.1 2.9 1.3 0.0 -4.1 -4.6 1.1 4.6 0.9 2.3 2.3 1.2 -2.4 3.1 1.4 3.7 2.2
Risk taking 6.1 9.0 22.8 2.8 -4.5 1.9 0.7 0.7 -3.2 -3.4 0.0 -1.7 2.2 -1.7 -2.9 -2.8 -4.2 -4.1 -3.5 -1.1 -2.9 -4.4 -3.1 -4.8
Ever had prostate specific antigen (PSA) test 0.7 0.8 4.7 -1.1 0.7 -0.6 0.5 0.5 0.9 -1.2 0.0 -0.5 -0.6 0.4 0.4 1.0 0.7 1.0 0.8 -2.2 0.7 0.9 1.1 0.9
Fractured/broken bones in last 5 years 2.3 3.0 7.1 1.6 -2.7 1.9 -1.6 -1.4 -1.2 -0.6 0.0 -2.1 0.5 -1.5 -0.9 -2.2 -2.2 -2.0 -2.4 0.5 -1.1 -2.6 -1.3 -2.4
Age started oral contraceptive pill 1.2 1.5 8.8 1.6 0.8 -1.1 1.4 1.1 -0.5 1.6 0.0 3.0 0.6 0.2 -0.3 0.7 0.3 0.5 0.6 2.5 -1.1 0.5 -1.4 -0.1
Diastolic blood pressure, automated reading 0.3 1.1 3.0 1.2 -1.0 1.0 0.8 0.7 -1.3 -0.2 0.0 0.6 0.7 -1.5 -1.0 -1.1 -1.1 -1.1 -1.1 1.1 -1.7 -0.9 -0.9 -1.1
Ever depressed for a whole week 0.3 0.4 1.9 1.0 0.2 -0.7 0.2 0.3 0.3 -0.6 0.0 1.1 -0.8 0.3 -0.7 0.3 -0.1 -0.1 0.3 0.4 -1.4 0.1 -1.0 -0.3
Unable to work because of sickness or disability 1.6 2.0 9.2 -1.5 -1.1 2.4 -2.0 -2.0 0.4 0.6 0.0 -3.0 -0.2 -1.5 0.9 -1.6 -0.9 -0.7 -1.5 -1.6 0.8 -0.8 1.5 -0.2
Commuting to job workplace: Cycle 0.9 1.1 5.0 1.0 -0.0 -2.2 1.2 1.5 -1.1 -1.3 0.0 1.2 -0.1 1.6 -1.1 1.4 0.1 0.2 1.1 -0.4 0.0 -0.2 -1.5 -0.6
Myopia 0.8 1.2 3.8 -0.6 1.3 -1.7 0.9 1.1 0.6 -0.2 0.0 0.2 -0.2 2.0 0.2 1.7 1.6 1.4 1.6 -0.0 1.4 1.2 0.5 0.8
Vascular/heart problems diagnosed by doctor 1.7 4.7 9.8 -1.9 2.6 -2.7 -0.9 -1.0 1.5 1.3 0.0 -0.2 -1.3 3.0 2.5 3.1 3.0 2.9 3.0 -1.5 2.6 2.5 2.0 1.9
Cholesterol lowering medication 0.4 0.5 1.6 -0.5 -0.1 1.3 -0.7 -0.7 0.9 0.7 0.0 -1.2 0.4 -1.1 0.3 -1.1 -0.0 -0.3 -0.7 1.0 0.5 -0.1 0.8 0.9
Medication: Omeprazole (e.g. Zanprol) 0.9 1.1 3.4 0.7 -1.3 1.8 -1.2 -1.3 0.5 0.2 0.0 -1.5 -0.2 -1.6 0.0 -1.6 -1.2 -1.1 -1.6 -0.3 -0.3 -1.2 -0.0 -0.7
Pain experienced in last month 0.3 0.5 2.8 0.8 0.1 -0.8 1.6 1.7 -0.4 -0.6 0.0 0.9 0.0 0.5 -0.9 0.5 -0.0 0.0 0.4 0.7 -0.9 0.1 -0.6 -0.3
Supplements: Calcium 1.5 1.6 6.7 -1.3 0.6 0.1 -2.6 -2.5 1.1 1.8 0.0 -0.5 -1.1 0.2 1.9 0.2 1.0 1.0 0.5 0.2 1.9 0.6 1.4 1.2
Basal cell carcinoma (self-reported) 1.1 1.3 3.2 -1.8 1.4 -0.4 -0.1 -0.1 1.3 1.4 0.0 -1.2 -0.4 0.6 0.8 1.2 1.5 1.4 1.0 -1.2 1.4 1.4 1.8 1.2
Heart attack/myocardial infarction (self-reported) 1.7 2.1 9.1 -0.0 -1.4 3.0 -1.0 -1.0 0.0 0.0 0.0 -2.1 0.8 -2.6 0.1 -2.4 -1.5 -1.4 -2.3 0.8 -1.3 -1.3 0.5 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.9 1.2 5.6 -0.8 -0.9 1.8 -1.6 -1.6 0.3 -0.2 0.0 -2.4 -1.4 -0.7 1.0 -1.2 -0.6 -0.5 -1.1 -0.9 -0.0 -0.7 1.1 -0.4
Heart disease (siblings) 0.4 0.5 1.3 0.6 -0.8 1.0 -0.7 -0.6 -0.7 -0.3 0.0 -0.4 1.2 -1.1 0.1 -0.8 -0.6 -0.5 -1.0 0.4 -0.4 -0.9 -0.3 -1.0
Alcohol drinker status: Previous 0.4 0.5 1.9 -1.0 0.1 1.1 -0.5 -0.7 0.4 0.6 0.0 -0.8 1.0 -1.1 0.7 -0.2 -0.2 0.1 -0.4 -1.4 -0.3 0.3 0.9 -0.1
Pack years of smoking 0.9 1.3 7.6 -1.2 -1.5 1.5 -0.1 -0.1 -0.4 -1.3 0.0 -2.8 0.7 -1.0 -0.5 -1.3 -0.9 -1.1 -1.2 -0.4 1.0 -1.4 0.9 -0.9
Impedance of whole body 0.2 1.2 5.1 -0.9 1.4 -1.1 0.2 0.2 0.5 -1.0 0.0 0.8 -0.7 1.1 0.6 1.5 1.4 1.4 1.3 -2.2 0.0 1.5 1.1 0.8
Leg fat mass (left) 0.3 1.1 5.1 -0.4 1.4 0.1 -0.5 -0.5 1.9 1.3 0.0 -0.2 0.1 0.2 1.2 0.1 1.1 1.0 0.7 0.8 0.8 1.4 1.2 2.3
Arm predicted mass (left) 0.1 0.4 1.8 0.3 0.7 -0.7 0.5 0.4 0.2 1.0 0.0 0.8 0.6 0.3 0.3 0.3 0.4 0.3 0.6 1.4 0.9 0.6 -0.3 1.1