[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr5:51,425,511-53,094,674

Best TWAS P=8.48e-16 · Best GWAS P=6.32e-58 conditioned to NaN

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Adipose Subcutaneous	ITGA1	0.11	0.00	enet	31	0.02	1.2e-02	-0.18	-8.1	8.5e-16	0.06	0.16	0.03	TRUE
9	GTEx	Lung	CTD-2366F13.2	0.07	0.12	lasso	1	0.09	3.7e-07	-7.86	-7.9	3.8e-15	0.02	1.00	0.00	TRUE
3	GTEx	Artery Aorta	ITGA2	0.15	0.00	enet	23	0.00	3.4e-01	-0.79	-7.0	3.3e-12	0.16	0.17	0.04	TRUE
8	GTEx	Lung	ITGA1	0.10	0.03	lasso	4	0.01	6.9e-02	-6.64	-7.0	3.3e-12	0.16	0.25	0.40	TRUE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ITGA1	0.05	0.03	blup	195	0.01	1.1e-02	-6.28	-6.8	7.9e-12	0.34	0.06	0.04	TRUE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	ITGA1	0.03	0.00	blup	196	0.01	1.0e-03	-6.05	6.6	5.4e-11	0.05	0.09	0.02	TRUE
14	YFS	Blood	ITGA2	0.03	0.03	lasso	4	0.03	1.0e-09	-5.42	6.4	1.3e-10	0.00	1.00	0.00	TRUE
4	GTEx	Artery Tibial	ITGA2	0.14	0.06	enet	18	0.08	1.5e-06	-6.99	-6.1	9.1e-10	-0.04	1.00	0.00	TRUE
13	METSIM	Adipose	MOCS2	0.04	0.01	enet	20	0.01	3.2e-03	-2.55	5.6	1.8e-08	0.09	0.11	0.03	TRUE
5	GTEx	Cells Transformed fibroblasts	ITGA2	0.07	0.01	lasso	9	0.02	1.2e-02	-5.37	5.4	8.5e-08	-0.08	0.26	0.13	TRUE
10	GTEx	Muscle Skeletal	ITGA1	0.13	0.00	enet	45	0.05	9.2e-06	3.78	-7.9	2.7e-15	0.12	0.35	0.03	FALSE
7	GTEx	Lung	ITGA2	0.17	0.21	lasso	2	0.20	2.8e-15	-7.86	-7.8	6.1e-15	0.01	1.00	0.00	FALSE
6	GTEx	Heart Left Ventricle	ITGA2	0.20	0.20	lasso	3	0.17	2.5e-09	-6.99	-7.0	3.4e-12	-0.03	1.00	0.00	FALSE
11	GTEx	Thyroid	ITGA1	0.11	0.02	lasso	12	0.03	4.7e-03	-5.37	-6.8	1.1e-11	0.02	0.46	0.02	FALSE
1	GTEx	Adipose Subcutaneous	ITGA2	0.11	0.09	lasso	1	0.07	1.7e-06	5.86	-5.9	4.6e-09	-0.14	0.86	0.00	FALSE
12	METSIM	Adipose	ITGA2	0.06	0.04	lasso	6	0.02	1.9e-04	5.86	-5.8	7.3e-09	-0.16	0.96	0.00	FALSE