[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr5:97,434,545-99,024,399

Best TWAS P=1.15e-16 · Best GWAS P=6.8e-15 conditioned to 0.985

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Lung	CTD-2007H13.3	0.05	0.04	lasso	2	0.03	3.9e-03	-7.8	-8.3	1.1e-16	0.94	0.01	0.97	TRUE
1	GTEx	Adipose Subcutaneous	RGMB-AS1	0.09	0.07	lasso	5	0.11	1.4e-09	-6.8	-7.4	1.5e-13	0.77	0.14	0.86	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	RGMB-AS1	0.03	0.01	blup	336	0.01	1.2e-02	-6.1	-7.0	1.9e-12	0.61	0.15	0.25	FALSE
7	GTEx	Pancreas	RGMB-AS1	0.28	0.07	lasso	6	0.05	5.1e-03	-5.9	-6.4	1.4e-10	0.59	0.07	0.58	FALSE
11	GTEx	Whole Blood	CTD-2007H13.3	0.04	0.03	lasso	4	0.02	1.1e-02	-6.7	-6.4	1.4e-10	0.91	0.04	0.92	FALSE
2	GTEx	Adipose Visceral Omentum	CTD-2007H13.3	0.08	0.01	enet	17	0.03	8.8e-03	-4.6	-6.4	1.6e-10	0.81	0.05	0.79	FALSE
3	GTEx	Artery Tibial	CTD-2007H13.3	0.05	0.03	lasso	4	0.03	3.2e-03	-5.0	-6.2	6.1e-10	0.80	0.18	0.50	FALSE
4	GTEx	Esophagus Mucosa	RGMB-AS1	0.08	0.03	lasso	6	0.01	3.4e-02	-5.6	-6.1	8.5e-10	0.69	0.37	0.11	FALSE
6	GTEx	Nerve Tibial	RGMB-AS1	0.08	0.09	enet	5	0.06	3.4e-05	-5.9	-6.1	9.7e-10	0.47	0.88	0.03	FALSE
10	GTEx	Thyroid	RGMB-AS1	0.19	0.16	lasso	5	0.16	4.2e-12	-6.5	-6.1	1.1e-09	0.55	0.94	0.06	FALSE
9	GTEx	Testis	RGMB-AS1	0.44	0.50	enet	16	0.48	1.2e-23	-6.1	-6.0	2.0e-09	0.48	0.99	0.01	FALSE
12	METSIM	Adipose	RGMB	0.03	0.01	blup	341	0.02	1.0e-03	-5.9	5.9	4.5e-09	-0.53	0.56	0.13	FALSE
8	GTEx	Testis	CHD1	0.15	0.08	lasso	4	0.08	1.4e-04	-5.0	5.6	2.6e-08	-0.80	0.03	0.94	FALSE