[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr5:97,434,545-99,024,399

Best TWAS P=1.15e-16 · Best GWAS P=6.8e-15 conditioned to 0.985

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RGMB-AS1 0.09 0.07 lasso 5 0.11 1.4e-09 -6.8 -7.4 1.5e-13 0.77 0.14 0.86 FALSE
2 GTEx Adipose Visceral Omentum CTD-2007H13.3 0.08 0.01 enet 17 0.03 8.8e-03 -4.6 -6.4 1.6e-10 0.81 0.05 0.79 FALSE
3 GTEx Artery Tibial CTD-2007H13.3 0.05 0.03 lasso 4 0.03 3.2e-03 -5.0 -6.2 6.1e-10 0.80 0.18 0.50 FALSE
4 GTEx Esophagus Mucosa RGMB-AS1 0.08 0.03 lasso 6 0.01 3.4e-02 -5.6 -6.1 8.5e-10 0.69 0.37 0.11 FALSE
5 GTEx Lung CTD-2007H13.3 0.05 0.04 lasso 2 0.03 3.9e-03 -7.8 -8.3 1.1e-16 0.94 0.01 0.97 TRUE
6 GTEx Nerve Tibial RGMB-AS1 0.08 0.09 enet 5 0.06 3.4e-05 -5.9 -6.1 9.7e-10 0.47 0.88 0.03 FALSE
7 GTEx Pancreas RGMB-AS1 0.28 0.07 lasso 6 0.05 5.1e-03 -5.9 -6.4 1.4e-10 0.59 0.07 0.58 FALSE
8 GTEx Testis CHD1 0.15 0.08 lasso 4 0.08 1.4e-04 -5.0 5.6 2.6e-08 -0.80 0.03 0.94 FALSE
9 GTEx Testis RGMB-AS1 0.44 0.50 enet 16 0.48 1.2e-23 -6.1 -6.0 2.0e-09 0.48 0.99 0.01 FALSE
10 GTEx Thyroid RGMB-AS1 0.19 0.16 lasso 5 0.16 4.2e-12 -6.5 -6.1 1.1e-09 0.55 0.94 0.06 FALSE
11 GTEx Whole Blood CTD-2007H13.3 0.04 0.03 lasso 4 0.02 1.1e-02 -6.7 -6.4 1.4e-10 0.91 0.04 0.92 FALSE
12 METSIM Adipose RGMB 0.03 0.01 blup 341 0.02 1.0e-03 -5.9 5.9 4.5e-09 -0.53 0.56 0.13 FALSE
13 ROSMAP Brain Pre-frontal Cortex RGMB-AS1 0.03 0.01 blup 336 0.01 1.2e-02 -6.1 -7.0 1.9e-12 0.61 0.15 0.25 FALSE