Best TWAS P=1.91e-32 · Best GWAS P=7.3e-29 conditioned to 0.00925
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | LOX | 0.11 | 0.06 | enet | 15 | 0.07 | 2.7e-10 | -1.5 | 6.8 | 1.0e-11 | -0.09 | 0.10 | 0.90 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SNCAIP | 0.04 | 0.00 | blup | 82 | 0.01 | 3.5e-02 | -4.5 | -5.7 | 1.5e-08 | -0.09 | 0.01 | 0.51 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | LOX | 0.02 | 0.01 | blup | 35 | 0.02 | 9.3e-04 | 8.1 | -11.9 | 1.9e-32 | -0.83 | 0.02 | 0.37 | TRUE |