TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Lung FEV1/FVC ratio
:
←
→
chr5:120,708,748-122,110,593
Best TWAS P=1.91e-32 · Best GWAS P=7.3e-29 conditioned to 0.00925
120.8M
121M
121.2M
121.4M
121.6M
121.8M
122M
0
5
10
15
20
25
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Lung Adenocarcinoma
LOX
0.02
0.01
blup
35
0.02
9.3e-04
8.1
-11.9
1.9e-32
-0.83
0.02
0.37
TRUE
1
METSIM
Adipose
LOX
0.11
0.06
enet
15
0.07
2.7e-10
-1.5
6.8
1.0e-11
-0.09
0.10
0.90
TRUE
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
SNCAIP
0.04
0.00
blup
82
0.01
3.5e-02
-4.5
-5.7
1.5e-08
-0.09
0.01
0.51
TRUE