[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr6:55,625,041-58,206,146

Best TWAS P=5.18e-09 · Best GWAS P=1.81e-15 conditioned to 1.01e-08

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	KIAA1586	0.10	0.03	lasso	5	0.03	3.2e-02	4.7	-5.8	5.2e-09	-0.32	0.12	0.34	TRUE
3	GTEx	Pancreas	PRIM2	0.18	0.04	lasso	5	0.04	9.4e-03	5.7	-5.5	3.2e-08	-0.27	0.03	0.51	TRUE
4	GTEx	Testis	DST	0.17	0.12	lasso	7	0.12	4.9e-06	5.4	-5.8	8.9e-09	-0.35	0.85	0.02	FALSE
6	The Cancer Genome Atlas	Colon Adenocarcinoma	BEND6	0.12	0.12	blup	44	0.15	5.7e-09	4.8	-5.7	1.6e-08	-0.18	0.02	0.97	FALSE
2	GTEx	Brain Hypothalamus	ZNF451	0.17	0.18	lasso	2	0.14	3.1e-04	5.5	5.5	4.5e-08	0.33	0.05	0.82	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	BEND6	0.05	0.08	blup	44	0.09	6.1e-18	4.9	-5.5	4.6e-08	-0.19	0.03	0.96	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	BEND6	0.06	0.08	blup	44	0.07	1.7e-08	4.9	-5.4	7.5e-08	-0.19	0.02	0.97	FALSE
10	The Cancer Genome Atlas	Soft Tissue Sarcoma	BEND6	0.09	0.07	lasso	5	0.08	2.9e-05	4.8	-5.4	8.3e-08	-0.19	0.04	0.90	FALSE
9	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	BEND6	0.06	0.04	blup	44	0.05	1.1e-03	4.3	-5.2	1.8e-07	-0.19	0.04	0.89	FALSE
7	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BEND6	0.11	0.10	lasso	3	0.13	1.4e-14	4.4	-5.1	3.0e-07	-0.19	0.02	0.97	FALSE