Best TWAS P=8.41e-10 · Best GWAS P=1.55e-08 conditioned to 0.263
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | SRPK2 | 0.02 | 0.01 | lasso | 8 | 0.02 | 3.7e-07 | -4.7 | -5.9 | 3.2e-09 | 0.55 | 0.11 | 0.87 | FALSE |
2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | LOC723809 | 0.05 | 0.05 | lasso | 2 | 0.05 | 3.4e-04 | -5.2 | 6.1 | 8.4e-10 | -0.82 | 0.01 | 0.69 | TRUE |