Best TWAS P=3.69e-09 · Best GWAS P=3.94e-07 conditioned to 0.121
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | INTS4L2 | 0.07 | 0.07 | blup | 214 | 0.09 | 9.6e-11 | 3.9 | -5.2 | 2.3e-07 | 0.49 | 0.15 | 0.71 | FALSE |
2 | GTEx | Skin Sun Exposed Lower leg | KCTD7 | 0.04 | 0.03 | enet | 13 | 0.04 | 1.8e-04 | -3.7 | -5.3 | 1.3e-07 | 0.73 | 0.15 | 0.57 | FALSE |
3 | YFS | Blood | VKORC1L1 | 0.22 | 0.10 | enet | 50 | 0.18 | 1.6e-57 | -4.7 | -5.9 | 3.7e-09 | 0.66 | 0.02 | 0.97 | TRUE |